KEGG_PENTOSE_PHOSPHATE_PATHWAY Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 ALDOB Fructose-bisphosphate aldolase B [1] -10.79[2] -10.40[3] -10.16[4] -14.77[5] -14.69[6] 0.20[7]
2 TALDO1 Transaldolase [8] -0.99[9] -1.52[10] -0.64[11] -0.45[12] -1.58[13] -1.81[14]
3 ALDOA Fructose-bisphosphate aldolase A [15] 2.55[16] 2.30[17] 1.62[18] 1.28[19] 1.90[20] -1.15[21]
4 PGD 6-phosphogluconate dehydrogenase, decarboxylating [22] -0.79[23] 0.52[24] 0.13[25] 0.82[26] -1.15[27] -1.67[28]
5 TKT Transketolase [29] 0.40[30] 0.80[31] 0.88[32] 1.06[33] 0.81[34] -2.12[35]
6 FBP1 Fructose-1,6-bisphosphatase 1 [36] -10.82[37] -9.27[38] -7.34[39] -12.30[40] -12.60[41] 0.69[42]
7 PGM1 Phosphoglucomutase-1 [43] -1.07[44] -0.13[45] 0.66[46] -1.04[47] -0.51[48] 0.75[49]
8 GPI Glucose-6-phosphate isomerase [50] 2.12[51] 1.50[52] 2.56[53] 1.82[54] 2.59[55] 1.86[56]
9 PFKL ATP-dependent 6-phosphofructokinase, liver type [57] 1.43[58] 1.62[59] 1.74[60] 0.70[61] 1.34[62] 0.73[63]
10 DERA Deoxyribose-phosphate aldolase [64] -1.01[65] -0.16[66] 0.46[67] -1.85[68] 0.13[69] -0.23[70]
11 RPE Ribulose-phosphate 3-epimerase [71] -0.71[72] -0.33[73] 0.09[74] -0.93[75] 0.27[76] -1.37[77]
12 PRPS1 Ribose-phosphate pyrophosphokinase 1 [78] [79] [80] [81] [82] [83] [84]
13 PGLS 6-phosphogluconolactonase [85] -0.43[86] 0.16[87] 1.01[88] -1.56[89] -0.57[90] -1.39[91]
14 ALDOC Fructose-bisphosphate aldolase C [92] -1.20[93] 0.45[94] 1.48[95] -0.85[96] -1.46[97] 0.37[98]
15 RBKS Ribokinase [99] -2.27[100] -1.25[101] -1.50[102] -4.79[103] -4.09[104] -0.98[105]
16 PFKP ATP-dependent 6-phosphofructokinase, platelet type [106] 0.15[107] -1.48[108] -5.87[109] 3.67[110] 3.40[111] -2.92[112]
17 RPIA Ribose-5-phosphate isomerase [113] -0.05[114] 0.12[115] -0.21[116] -0.97[117] -0.86[118] -3.91[119]
18 PRPS2 Ribose-phosphate pyrophosphokinase 2 [120] [121] [122] [123] [124] [125] [126]
19 G6PD Glucose-6-phosphate 1-dehydrogenase [127] 3.03[128] 1.19[129] 1.19[130] 4.64[131] 2.67[132] -2.51[133]
20 H6PD GDH/6PGL endoplasmic bifunctional protein [134] 1.76[135] 2.76[136] 2.11[137] 1.09[138] 2.43[139] 4.29[140]
21 PGM2 Phosphoglucomutase-2 [141] 1.11[142] 1.35[143] 1.80[144] 0.95[145] 3.04[146] 0.03[147]
22 PFKM ATP-dependent 6-phosphofructokinase, muscle type [148] -1.22[149] -0.50[150] 4.77[151] 3.47[152] 4.94[153] 0.93[154]
23 FBP2 Fructose-1,6-bisphosphatase isozyme 2 [155] -1.06[156] -0.06[157] 1.34[158] -3.01[159] -5.27[160] -2.54[161]
24 TKTL2 Transketolase-like protein 2 [162] [163] [164] [165] [166] [167] [168]
25 RPEL1 Ribulose-phosphate 3-epimerase-like protein 1 [169] [170] [171] [172] [173] [174] [175]
26 TKTL1 Transketolase-like protein 1 [176] [177] [178] [179] [180] [181] [182]
27 PRPS1L1 Ribose-phosphate pyrophosphokinase 3 [183] [184] [185] [186] [187] [188] [189]
[1]
ref_hepatocyte ALDOB
Mean 487
Standard deviation 6.5e+02
Values 0.2 12 9.8e+02 61 1.4e+03
[2]
HepG2 ALDOB
Mean 0.48
Standard deviation 0.084
Values 0.54 0.42
[3]
HepG2.C3A ALDOB
Mean 0.511
Standard deviation 0.25
Values 0.69 0.33
[4]
HuH.7 ALDOB
Mean 0.481
Standard deviation 0.53
Values 0.22 1.1 0.13
[5]
SNU475 ALDOB
Mean 0.0293
Standard deviation 0.0087
Values 0.023 0.035
[6]
THLE ALDOB
Mean 0.0166
Standard deviation 0.0067
Values 0.012 0.021
[7]
liver ALDOB
Mean 780
Standard deviation 5.1e+02
Values 5.5e+02 1.5e+03 5.7e+02 4.6e+02
[8]
ref_hepatocyte TALDO1
Mean 126
Standard deviation 45
Values 1.2e+02 2.1e+02 94 1.1e+02 1.1e+02
[9]
HepG2 TALDO1
Mean 111
Standard deviation 26
Values 1.3e+02 92
[10]
HepG2.C3A TALDO1
Mean 62.4
Standard deviation 9
Values 56 69
[11]
HuH.7 TALDO1
Mean 91.8
Standard deviation 28
Values 1.1e+02 60 1.1e+02
[12]
SNU475 TALDO1
Mean 156
Standard deviation 34
Values 1.8e+02 1.3e+02
[13]
THLE TALDO1
Mean 37.9
Standard deviation 9.6
Values 31 45
[14]
liver TALDO1
Mean 50.3
Standard deviation 37
Values 23 73 91 14
[15]
ref_hepatocyte ALDOA
Mean 111
Standard deviation 69
Values 1.2e+02 99 72 2.2e+02 44
[16]
HepG2 ALDOA
Mean 1.13e+03
Standard deviation 3.1e+02
Values 1.4e+03 9.1e+02
[17]
HepG2.C3A ALDOA
Mean 778
Standard deviation 4.3
Values 7.7e+02 7.8e+02
[18]
HuH.7 ALDOA
Mean 387
Standard deviation 91
Values 4.7e+02 2.9e+02 4e+02
[19]
SNU475 ALDOA
Mean 456
Standard deviation 45
Values 4.9e+02 4.2e+02
[20]
THLE ALDOA
Mean 373
Standard deviation 79
Values 3.2e+02 4.3e+02
[21]
liver ALDOA
Mean 69.8
Standard deviation 59
Values 29 76 1.5e+02 23
[22]
ref_hepatocyte PGD
Mean 93.2
Standard deviation 55
Values 91 1.7e+02 52 1.1e+02 34
[23]
HepG2 PGD
Mean 93.5
Standard deviation 3.9
Values 96 91
[24]
HepG2.C3A PGD
Mean 190
Standard deviation 27
Values 2.1e+02 1.7e+02
[25]
HuH.7 PGD
Mean 115
Standard deviation 2
Values 1.2e+02 1.2e+02 1.1e+02
[26]
SNU475 PGD
Mean 277
Standard deviation 55
Values 3.2e+02 2.4e+02
[27]
THLE PGD
Mean 37.6
Standard deviation 7.3
Values 32 43
[28]
liver PGD
Mean 40.9
Standard deviation 18
Values 34 38 67 25
[29]
ref_hepatocyte TKT
Mean 86.7
Standard deviation 36
Values 74 92 1.1e+02 1.2e+02 31
[30]
HepG2 TKT
Mean 199
Standard deviation 1.1e+02
Values 2.8e+02 1.2e+02
[31]
HepG2.C3A TKT
Mean 213
Standard deviation 92
Values 2.8e+02 1.5e+02
[32]
HuH.7 TKT
Mean 181
Standard deviation 32
Values 1.8e+02 2.2e+02 1.5e+02
[33]
SNU475 TKT
Mean 303
Standard deviation 1e+02
Values 3.7e+02 2.3e+02
[34]
THLE TKT
Mean 136
Standard deviation 17
Values 1.2e+02 1.5e+02
[35]
liver TKT
Mean 27.9
Standard deviation 9
Values 36 15 32 28
[36]
ref_hepatocyte FBP1
Mean 79.5
Standard deviation 1e+02
Values 0 6.8 1.8e+02 10 2e+02
[37]
HepG2 FBP1
Mean 0.0766
Standard deviation 0.0052
Values 0.08 0.073
[38]
HepG2.C3A FBP1
Mean 0.183
Standard deviation 0.016
Values 0.19 0.17
[39]
HuH.7 FBP1
Mean 0.554
Standard deviation 0.26
Values 0.62 0.27 0.77
[40]
SNU475 FBP1
Mean 0.0266
Standard deviation 0.0018
Values 0.028 0.025
[41]
THLE FBP1
Mean 0.0115
Standard deviation 0.0088
Values 0.018 0.0053
[42]
liver FBP1
Mean 179
Standard deviation 1.4e+02
Values 54 2.6e+02 3.4e+02 60
[43]
ref_hepatocyte PGM1
Mean 48.7
Standard deviation 37
Values 17 38 81 13 94
[44]
HepG2 PGM1
Mean 40.3
Standard deviation 11
Values 32 48
[45]
HepG2.C3A PGM1
Mean 63.1
Standard deviation 8.8
Values 69 57
[46]
HuH.7 PGM1
Mean 87
Standard deviation 8.2
Values 96 80 84
[47]
SNU475 PGM1
Mean 39.9
Standard deviation 9.8
Values 47 33
[48]
THLE PGM1
Mean 30.8
Standard deviation 0.38
Values 31 31
[49]
liver PGM1
Mean 114
Standard deviation 21
Values 91 1.3e+02 1.3e+02 1e+02
[50]
ref_hepatocyte GPI
Mean 25.8
Standard deviation 12
Values 20 19 47 19 24
[51]
HepG2 GPI
Mean 195
Standard deviation 10
Values 2e+02 1.9e+02
[52]
HepG2.C3A GPI
Mean 103
Standard deviation 3.7
Values 1.1e+02 1e+02
[53]
HuH.7 GPI
Mean 172
Standard deviation 28
Values 2e+02 1.5e+02 1.6e+02
[54]
SNU475 GPI
Mean 153
Standard deviation 14
Values 1.6e+02 1.4e+02
[55]
THLE GPI
Mean 139
Standard deviation 15
Values 1.3e+02 1.5e+02
[56]
liver GPI
Mean 131
Standard deviation 58
Values 87 1.7e+02 1.9e+02 74
[57]
ref_hepatocyte PFKL
Mean 23.2
Standard deviation 11
Values 40 17 25 9.3 25
[58]
HepG2 PFKL
Mean 109
Standard deviation 8.2
Values 1.1e+02 1e+02
[59]
HepG2.C3A PFKL
Mean 101
Standard deviation 29
Values 1.2e+02 80
[60]
HuH.7 PFKL
Mean 87.4
Standard deviation 22
Values 1e+02 62 99
[61]
SNU475 PFKL
Mean 63.3
Standard deviation 25
Values 81 46
[62]
THLE PFKL
Mean 52.7
Standard deviation 1.5
Values 52 54
[63]
liver PFKL
Mean 53.7
Standard deviation 15
Values 40 55 73 47
[64]
ref_hepatocyte DERA
Mean 23
Standard deviation 10
Values 23 32 21 7 31
[65]
HepG2 DERA
Mean 19.8
Standard deviation 1.1
Values 19 21
[66]
HepG2.C3A DERA
Mean 29.2
Standard deviation 13
Values 20 38
[67]
HuH.7 DERA
Mean 35.6
Standard deviation 0.44
Values 35 36 36
[68]
SNU475 DERA
Mean 10.7
Standard deviation 2.6
Values 13 8.8
[69]
THLE DERA
Mean 22.5
Standard deviation 2.3
Values 21 24
[70]
liver DERA
Mean 27.3
Standard deviation 13
Values 16 42 35 16
[71]
ref_hepatocyte RPE
Mean 20
Standard deviation 15
Values 33 38 6.6 13 9.2
[72]
HepG2 RPE
Mean 21.2
Standard deviation 5.3
Values 17 25
[73]
HepG2.C3A RPE
Mean 22.5
Standard deviation 11
Values 15 30
[74]
HuH.7 RPE
Mean 24.1
Standard deviation 5.3
Values 29 18 25
[75]
SNU475 RPE
Mean 17.7
Standard deviation 1.8
Values 19 16
[76]
THLE RPE
Mean 21.7
Standard deviation 1.8
Values 20 23
[77]
liver RPE
Mean 10.8
Standard deviation 3.5
Values 16 7.6 11 9.4
[78]
ref_hepatocyte PRPS1
Mean 18.8
Standard deviation 5.2
Values 13 26 16 22 17
[79]
HepG2 PRPS1
Missing
[80]
HepG2.C3A PRPS1
Missing
[81]
HuH.7 PRPS1
Missing
[82]
SNU475 PRPS1
Missing
[83]
THLE PRPS1
Missing
[84]
liver PRPS1
Missing
[85]
ref_hepatocyte PGLS
Mean 16.8
Standard deviation 7.3
Values 9 12 27 16 20
[86]
HepG2 PGLS
Mean 21.7
Standard deviation 7.9
Values 27 16
[87]
HepG2.C3A PGLS
Mean 26.6
Standard deviation 11
Values 34 19
[88]
HuH.7 PGLS
Mean 38.1
Standard deviation 2.8
Values 39 35 41
[89]
SNU475 PGLS
Mean 9.59
Standard deviation 3.3
Values 12 7.2
[90]
THLE PGLS
Mean 10.1
Standard deviation 0.39
Values 9.9 10
[91]
liver PGLS
Mean 8.92
Standard deviation 7.1
Values 3.4 15 15 2.2
[92]
ref_hepatocyte ALDOC
Mean 16.2
Standard deviation 17
Values 6 2 37 3.5 32
[93]
HepG2 ALDOC
Mean 12.3
Standard deviation 1.4
Values 11 13
[94]
HepG2.C3A ALDOC
Mean 31.3
Standard deviation 5.9
Values 35 27
[95]
HuH.7 ALDOC
Mean 51.1
Standard deviation 17
Values 39 71 43
[96]
SNU475 ALDOC
Mean 15.1
Standard deviation 2.5
Values 13 17
[97]
THLE ALDOC
Mean 5.29
Standard deviation 2.2
Values 6.8 3.7
[98]
liver ALDOC
Mean 29.1
Standard deviation 10
Values 23 32 42 20
[99]
ref_hepatocyte RBKS
Mean 13.7
Standard deviation 8.4
Values 8.8 14 21 2.3 23
[100]
HepG2 RBKS
Mean 4.94
Standard deviation 0.87
Values 4.3 5.6
[101]
HepG2.C3A RBKS
Mean 8.2
Standard deviation 0.86
Values 7.6 8.8
[102]
HuH.7 RBKS
Mean 5.48
Standard deviation 0.83
Values 5.1 4.9 6.4
[103]
SNU475 RBKS
Mean 0.833
Standard deviation 0.32
Values 1.1 0.6
[104]
THLE RBKS
Mean 0.723
Standard deviation 0.0012
Values 0.72 0.72
[105]
liver RBKS
Mean 9.75
Standard deviation 5.9
Values 4.9 15 15 4.4
[106]
ref_hepatocyte PFKP
Mean 9.86
Standard deviation 17
Values 1 39 0.3 8.4 0.58
[107]
HepG2 PFKP
Mean 19
Standard deviation 13
Values 28 9.8
[108]
HepG2.C3A PFKP
Mean 5.02
Standard deviation 1
Values 4.3 5.8
[109]
HuH.7 PFKP
Mean 0.191
Standard deviation 0.11
Values 0.24 0.27 0.066
[110]
SNU475 PFKP
Mean 212
Standard deviation 73
Values 2.6e+02 1.6e+02
[111]
THLE PFKP
Mean 93.5
Standard deviation 18
Values 81 1.1e+02
[112]
liver PFKP
Mean 1.82
Standard deviation 0.73
Values 2 1.1 2.8 1.4
[113]
ref_hepatocyte RPIA
Mean 9.8
Standard deviation 9.8
Values 25 14 3.2 4.6 2.1
[114]
HepG2 RPIA
Mean 16.5
Standard deviation 0.34
Values 17 16
[115]
HepG2.C3A RPIA
Mean 15.1
Standard deviation 2
Values 14 17
[116]
HuH.7 RPIA
Mean 9.56
Standard deviation 4.3
Values 11 4.8 13
[117]
SNU475 RPIA
Mean 8.38
Standard deviation 0.35
Values 8.6 8.1
[118]
THLE RPIA
Mean 4.86
Standard deviation 1.1
Values 4.1 5.6
[119]
liver RPIA
Mean 0.91
Standard deviation 0.15
Values 1.1 0.71 0.95 0.91
[120]
ref_hepatocyte PRPS2
Mean 7.85
Standard deviation 4.2
Values 6.8 14 5.9 2.7 10
[121]
HepG2 PRPS2
Missing
[122]
HepG2.C3A PRPS2
Missing
[123]
HuH.7 PRPS2
Missing
[124]
SNU475 PRPS2
Missing
[125]
THLE PRPS2
Missing
[126]
liver PRPS2
Missing
[127]
ref_hepatocyte G6PD
Mean 7
Standard deviation 9.9
Values 24 7.7 1.1 1.2 1.1
[128]
HepG2 G6PD
Mean 99.6
Standard deviation 38
Values 1.3e+02 73
[129]
HepG2.C3A G6PD
Mean 22.6
Standard deviation 2
Values 24 21
[130]
HuH.7 G6PD
Mean 18.1
Standard deviation 6.7
Values 24 11 19
[131]
SNU475 G6PD
Mean 293
Standard deviation 1.9e+02
Values 4.3e+02 1.6e+02
[132]
THLE G6PD
Mean 39.9
Standard deviation 6.1
Values 36 44
[133]
liver G6PD
Mean 1.72
Standard deviation 0.72
Values 1 1.6 2.7 1.6
[134]
ref_hepatocyte H6PD
Mean 6.55
Standard deviation 4.5
Values 2.6 4 12 3.3 11
[135]
HepG2 H6PD
Mean 38.6
Standard deviation 6.9
Values 44 34
[136]
HepG2.C3A H6PD
Mean 63
Standard deviation 17
Values 75 51
[137]
HuH.7 H6PD
Mean 31.9
Standard deviation 5.4
Values 33 36 26
[138]
SNU475 H6PD
Mean 23.5
Standard deviation 15
Values 34 13
[139]
THLE H6PD
Mean 31.8
Standard deviation 0.33
Values 32 32
[140]
liver H6PD
Mean 179
Standard deviation 61
Values 2.2e+02 1e+02 1.6e+02 2.3e+02
[141]
ref_hepatocyte PGM2
Mean 4.67
Standard deviation 2.7
Values 6.5 8.2 1.3 4.4 2.9
[142]
HepG2 PGM2
Mean 17.6
Standard deviation 5.6
Values 14 22
[143]
HepG2.C3A PGM2
Mean 16.8
Standard deviation 7.6
Values 11 22
[144]
HuH.7 PGM2
Mean 18.4
Standard deviation 3.6
Values 20 14 20
[145]
SNU475 PGM2
Mean 15.2
Standard deviation 0.74
Values 16 15
[146]
THLE PGM2
Mean 34.5
Standard deviation 5.3
Values 31 38
[147]
liver PGM2
Mean 6.66
Standard deviation 1.3
Values 8.6 5.5 6 6.5
[148]
ref_hepatocyte PFKM
Mean 1.41
Standard deviation 1.5
Values 0.15 4 1.1 0.38 1.5
[149]
HepG2 PFKM
Mean 1.05
Standard deviation 0.053
Values 1.1 1
[150]
HepG2.C3A PFKM
Mean 1.41
Standard deviation 0.22
Values 1.3 1.6
[151]
HuH.7 PFKM
Mean 43.4
Standard deviation 9.4
Values 48 33 49
[152]
SNU475 PFKM
Mean 26.2
Standard deviation 3.8
Values 29 23
[153]
THLE PFKM
Mean 38.8
Standard deviation 5.8
Values 35 43
[154]
liver PFKM
Mean 3.75
Standard deviation 0.6
Values 4 3.9 4.2 2.9
[155]
ref_hepatocyte FBP2
Mean 0.127
Standard deviation 0.25
Values 0 0 0 0.57 0.065
[156]
HepG2 FBP2
Mean 0.105
Standard deviation 0.0029
Values 0.1 0.11
[157]
HepG2.C3A FBP2
Mean 0.172
Standard deviation 0.046
Values 0.2 0.14
[158]
HuH.7 FBP2
Mean 0.363
Standard deviation 0.14
Values 0.4 0.48 0.21
[159]
SNU475 FBP2
Mean 0.0264
Standard deviation 0.0086
Values 0.032 0.02
[160]
THLE FBP2
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[161]
liver FBP2
Mean 0.0304
Standard deviation 0.023
Values 0.043 0 0.026 0.053
[162]
ref_hepatocyte TKTL2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[163]
HepG2 TKTL2
Mean 0
Standard deviation 0
Values 0 0
[164]
HepG2.C3A TKTL2
Mean 0
Standard deviation 0
Values 0 0
[165]
HuH.7 TKTL2
Mean 0
Standard deviation 0
Values 0 0 0
[166]
SNU475 TKTL2
Mean 0.0148
Standard deviation 0.0078
Values 0.0093 0.02
[167]
THLE TKTL2
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[168]
liver TKTL2
Mean 0.00357
Standard deviation 0.0071
Values 0.014 0 0 0
[169]
ref_hepatocyte RPEL1
Missing
[170]
HepG2 RPEL1
Missing
[171]
HepG2.C3A RPEL1
Missing
[172]
HuH.7 RPEL1
Missing
[173]
SNU475 RPEL1
Missing
[174]
THLE RPEL1
Missing
[175]
liver RPEL1
Missing
[176]
ref_hepatocyte TKTL1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[177]
HepG2 TKTL1
Mean 0.00429
Standard deviation 0.0061
Values 0 0.0086
[178]
HepG2.C3A TKTL1
Mean 0
Standard deviation 0
Values 0 0
[179]
HuH.7 TKTL1
Mean 0
Standard deviation 0
Values 0 0 0
[180]
SNU475 TKTL1
Mean 0.408
Standard deviation 0.046
Values 0.38 0.44
[181]
THLE TKTL1
Mean 0.0136
Standard deviation 0.011
Values 0.0059 0.021
[182]
liver TKTL1
Mean 0.0284
Standard deviation 0.034
Values 0 0.024 0.077 0.013
[183]
ref_hepatocyte PRPS1L1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[184]
HepG2 PRPS1L1
Missing
[185]
HepG2.C3A PRPS1L1
Missing
[186]
HuH.7 PRPS1L1
Missing
[187]
SNU475 PRPS1L1
Missing
[188]
THLE PRPS1L1
Missing
[189]
liver PRPS1L1
Missing