KEGG_PANTOTHENATE_AND_COA_BIOSYNTHESIS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 DPYS Dihydropyrimidinase [1] [2] [3] -15.73[4] -11.52[5] [6] 0.01[7]
2 VNN1 Pantetheinase [8] -3.16[9] -1.92[10] -7.07[11] -8.28[12] -1.37[13] -0.20[14]
3 UPB1 Beta-ureidopropionase [15] -7.17[16] -5.65[17] -4.24[18] -6.95[19] -12.56[20] -0.70[21]
4 PPCS Phosphopantothenate--cysteine ligase [22] -0.65[23] -1.23[24] -2.04[25] -0.75[26] -1.20[27] -1.92[28]
5 COASY Bifunctional coenzyme A synthase [29] 1.62[30] 1.76[31] 0.33[32] 0.45[33] 0.21[34] -1.14[35]
6 PANK2 Pantothenate kinase 2, mitochondrial [36] 1.43[37] 0.64[38] -0.50[39] 1.20[40] 0.48[41] -1.87[42]
7 ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 2.28[43] 2.48[44] 2.16[45] 1.28[46] -1.43[47] 2.15[48]
8 PANK3 Pantothenate kinase 3 [49] 1.36[50] 1.30[51] 3.42[52] 1.98[53] 1.21[54] 1.28[55]
9 PANK1 Pantothenate kinase 1 [56] 0.28[57] 1.54[58] -0.19[59] -0.27[60] -0.44[61] 1.74[62]
10 DPYD Dihydropyrimidine dehydrogenase [NADP(+)] [63] -3.69[64] -3.58[65] 1.78[66] 2.23[67] 1.11[68] 2.65[69]
11 BCAT2 Branched-chain-amino-acid aminotransferase, mitochondrial [70] -1.42[71] -1.30[72] 1.50[73] 2.41[74] 1.39[75] -0.50[76]
12 PANK4 Pantothenate kinase 4 [77] 1.72[78] 1.35[79] 0.54[80] 1.72[81] 1.58[82] -0.45[83]
13 ENPP3 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 1.35[84] 2.61[85] -3.04[86] -2.58[87] -5.15[88] -2.72[89]
14 PPCDC Phosphopantothenoylcysteine decarboxylase [90] 1.53[91] 1.25[92] -0.01[93] 1.63[94] 0.99[95] -1.04[96]
15 VNN2 Vascular non-inflammatory molecule 2 [97] -2.88[98] -2.35[99] 1.81[100] -4.11[101] -0.04[102] -0.26[103]
16 BCAT1 Branched-chain-amino-acid aminotransferase, cytosolic [104] 4.73[105] 3.63[106] 5.73[107] 5.71[108] 6.69[109] -0.69[110]
[1]
ref_hepatocyte DPYS
Mean 68
Standard deviation 1e+02
Values 0 3.8 96 1.4 2.4e+02
[2]
HepG2 DPYS
Mean 0
Standard deviation 0
Values 0 0
[3]
HepG2.C3A DPYS
Mean 0
Standard deviation 0
Values 0 0
[4]
HuH.7 DPYS
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[5]
SNU475 DPYS
Mean 0.0152
Standard deviation 0.022
Values 0 0.03
[6]
THLE DPYS
Mean 0
Standard deviation 0
Values 0 0
[7]
liver DPYS
Mean 161
Standard deviation 36
Values 2.1e+02 1.6e+02 1.2e+02 1.6e+02
[8]
ref_hepatocyte VNN1
Mean 38.6
Standard deviation 33
Values 0.67 57 24 86 25
[9]
HepG2 VNN1
Mean 3.91
Standard deviation 1.5
Values 2.9 4.9
[10]
HepG2.C3A VNN1
Mean 14.9
Standard deviation 9
Values 8.5 21
[11]
HuH.7 VNN1
Mean 0.492
Standard deviation 0.22
Values 0.36 0.75 0.37
[12]
SNU475 VNN1
Mean 0.0813
Standard deviation 0.043
Values 0.051 0.11
[13]
THLE VNN1
Mean 14.8
Standard deviation 3.6
Values 17 12
[14]
liver VNN1
Mean 79.3
Standard deviation 2.3
Values 78 82 81 77
[15]
ref_hepatocyte UPB1
Mean 34.1
Standard deviation 46
Values 0.23 4 52 8 1.1e+02
[16]
HepG2 UPB1
Mean 0.216
Standard deviation 0.0023
Values 0.22 0.21
[17]
HepG2.C3A UPB1
Mean 1
Standard deviation 0.041
Values 0.97 1
[18]
HuH.7 UPB1
Mean 3.08
Standard deviation 0.98
Values 3.2 2 4
[19]
SNU475 UPB1
Mean 0.181
Standard deviation 0.11
Values 0.26 0.1
[20]
THLE UPB1
Mean 0.00562
Standard deviation 0.00042
Values 0.0059 0.0053
[21]
liver UPB1
Mean 49.6
Standard deviation 25
Values 30 75 67 26
[22]
ref_hepatocyte PPCS
Mean 31.6
Standard deviation 14
Values 37 26 34 12 50
[23]
HepG2 PPCS
Mean 18.3
Standard deviation 1.1
Values 18 19
[24]
HepG2.C3A PPCS
Mean 19.7
Standard deviation 3.6
Values 17 22
[25]
HuH.7 PPCS
Mean 13.2
Standard deviation 2.4
Values 12 12 16
[26]
SNU475 PPCS
Mean 12.3
Standard deviation 2.6
Values 14 11
[27]
THLE PPCS
Mean 13.7
Standard deviation 2.2
Values 12 15
[28]
liver PPCS
Mean 19.7
Standard deviation 17
Values 5.3 35 35 4.3
[29]
ref_hepatocyte COASY
Mean 27.4
Standard deviation 9.2
Values 27 14 40 28 27
[30]
HepG2 COASY
Mean 76.2
Standard deviation 9.1
Values 83 70
[31]
HepG2.C3A COASY
Mean 136
Standard deviation 28
Values 1.6e+02 1.2e+02
[32]
HuH.7 COASY
Mean 58.8
Standard deviation 12
Values 67 45 64
[33]
SNU475 COASY
Mean 24.4
Standard deviation 2.3
Values 26 23
[34]
THLE COASY
Mean 31.5
Standard deviation 0.16
Values 31 32
[35]
liver COASY
Mean 29.4
Standard deviation 24
Values 7.7 53 46 10
[36]
ref_hepatocyte PANK2
Mean 11.5
Standard deviation 9
Values 27 7.9 7.2 8.8 6.3
[37]
HepG2 PANK2
Mean 28.1
Standard deviation 4.2
Values 25 31
[38]
HepG2.C3A PANK2
Mean 26.3
Standard deviation 0.44
Values 26 27
[39]
HuH.7 PANK2
Mean 13.9
Standard deviation 3.5
Values 15 9.9 17
[40]
SNU475 PANK2
Mean 17.3
Standard deviation 0.65
Values 17 18
[41]
THLE PANK2
Mean 16
Standard deviation 2.4
Values 14 18
[42]
liver PANK2
Mean 7.46
Standard deviation 1.5
Values 8.9 6.6 5.8 8.4
[43]
ref_hepatocyte ENPP1
Mean 6.12
Standard deviation 3.9
Values 9.8 2.9 6.7 1.4 9.9
[44]
HepG2 ENPP1
Mean 27.1
Standard deviation 7.8
Values 22 33
[45]
HepG2.C3A ENPP1
Mean 50
Standard deviation 14
Values 60 40
[46]
HuH.7 ENPP1
Mean 46.7
Standard deviation 8.1
Values 46 55 39
[47]
SNU475 ENPP1
Mean 9.73
Standard deviation 5.5
Values 14 5.8
[48]
THLE ENPP1
Mean 2.26
Standard deviation 0.11
Values 2.2 2.3
[49]
liver ENPP1
Mean 64.2
Standard deviation 27
Values 56 1e+02 38 61
[50]
ref_hepatocyte PANK3
Mean 6.05
Standard deviation 2.6
Values 7.1 10 4.6 4.3 4
[51]
HepG2 PANK3
Mean 14.1
Standard deviation 7.5
Values 8.8 19
[52]
HepG2.C3A PANK3
Mean 21.9
Standard deviation 6.1
Values 18 26
[53]
HuH.7 PANK3
Mean 111
Standard deviation 53
Values 1e+02 1.7e+02 61
[54]
SNU475 PANK3
Mean 15.6
Standard deviation 2.6
Values 17 14
[55]
THLE PANK3
Mean 14
Standard deviation 2.7
Values 12 16
[56]
liver PANK3
Mean 34.8
Standard deviation 22
Values 47 19 14 59
[57]
ref_hepatocyte PANK1
Mean 5.48
Standard deviation 3.9
Values 7.9 1.8 7.2 0.88 9.7
[58]
HepG2 PANK1
Mean 6.06
Standard deviation 0.93
Values 5.4 6.7
[59]
HepG2.C3A PANK1
Mean 23.4
Standard deviation 1.4
Values 24 22
[60]
HuH.7 PANK1
Mean 8.2
Standard deviation 1.2
Values 7.3 9.5 7.7
[61]
SNU475 PANK1
Mean 2.98
Standard deviation 0.56
Values 3.4 2.6
[62]
THLE PANK1
Mean 4.02
Standard deviation 0.35
Values 3.8 4.3
[63]
liver PANK1
Mean 43.2
Standard deviation 8.1
Values 41 50 33 49
[64]
ref_hepatocyte DPYD
Mean 5.41
Standard deviation 7.8
Values 0.66 1.2 5.5 0.79 19
[65]
HepG2 DPYD
Mean 0.381
Standard deviation 0.23
Values 0.22 0.54
[66]
HepG2.C3A DPYD
Mean 0.663
Standard deviation 0.13
Values 0.76 0.57
[67]
HuH.7 DPYD
Mean 31.7
Standard deviation 5.8
Values 29 38 28
[68]
SNU475 DPYD
Mean 16.6
Standard deviation 0.43
Values 17 16
[69]
THLE DPYD
Mean 11.6
Standard deviation 1
Values 11 12
[70]
liver DPYD
Mean 80.3
Standard deviation 30
Values 93 69 45 1.1e+02
[71]
ref_hepatocyte BCAT2
Mean 3.91
Standard deviation 2.4
Values 0.36 6.6 4.6 2.9 5
[72]
HepG2 BCAT2
Mean 1.33
Standard deviation 0.16
Values 1.4 1.2
[73]
HepG2.C3A BCAT2
Mean 2.32
Standard deviation 0.055
Values 2.4 2.3
[74]
HuH.7 BCAT2
Mean 18.9
Standard deviation 8.7
Values 23 8.8 24
[75]
SNU475 BCAT2
Mean 13.6
Standard deviation 2.8
Values 16 12
[76]
THLE BCAT2
Mean 10.2
Standard deviation 1.4
Values 9.2 11
[77]
liver BCAT2
Mean 6.53
Standard deviation 4.8
Values 2.3 13 7.9 3.2
[78]
ref_hepatocyte PANK4
Mean 3.62
Standard deviation 0.96
Values 3.2 2.5 4 5.1 3.3
[79]
HepG2 PANK4
Mean 10.8
Standard deviation 2.4
Values 13 9.1
[80]
HepG2.C3A PANK4
Mean 13.5
Standard deviation 3.3
Values 16 11
[81]
HuH.7 PANK4
Mean 9.01
Standard deviation 1.4
Values 8.8 7.7 11
[82]
SNU475 PANK4
Mean 7.81
Standard deviation 0.89
Values 8.4 7.2
[83]
THLE PANK4
Mean 10.8
Standard deviation 0.68
Values 10 11
[84]
liver PANK4
Mean 6.26
Standard deviation 1.5
Values 5 5 7.8 7.3
[85]
ref_hepatocyte ENPP3
Mean 3.1
Standard deviation 5.7
Values 13 0.18 0.48 0 1.7
[86]
HepG2 ENPP3
Mean 7.2
Standard deviation 2.6
Values 5.4 9
[87]
HepG2.C3A ENPP3
Mean 27.8
Standard deviation 0.8
Values 28 27
[88]
HuH.7 ENPP3
Mean 0.644
Standard deviation 0.37
Values 0.5 1.1 0.37
[89]
SNU475 ENPP3
Mean 0.341
Standard deviation 0.03
Values 0.36 0.32
[90]
THLE ENPP3
Mean 0.0866
Standard deviation 0.0054
Values 0.083 0.09
[91]
liver ENPP3
Mean 1.12
Standard deviation 0.72
Values 1.2 2.1 0.69 0.46
[92]
ref_hepatocyte PPCDC
Mean 2.28
Standard deviation 1
Values 0.48 2.4 2.5 3.2 2.7
[93]
HepG2 PPCDC
Mean 5.99
Standard deviation 0.55
Values 5.6 6.4
[94]
HepG2.C3A PPCDC
Mean 7.96
Standard deviation 1.6
Values 6.8 9.1
[95]
HuH.7 PPCDC
Mean 3.86
Standard deviation 1.5
Values 3.9 2.3 5.4
[96]
SNU475 PPCDC
Mean 4.63
Standard deviation 0.87
Values 4 5.2
[97]
THLE PPCDC
Mean 4.51
Standard deviation 0.76
Values 4 5
[98]
liver PPCDC
Mean 2.62
Standard deviation 0.76
Values 2.3 3 3.5 1.8
[99]
ref_hepatocyte VNN2
Mean 1.2
Standard deviation 0.91
Values 0.44 1.9 1.9 0 1.7
[100]
HepG2 VNN2
Mean 0.147
Standard deviation 0.075
Values 0.2 0.094
[101]
HepG2.C3A VNN2
Mean 0.345
Standard deviation 0.063
Values 0.39 0.3
[102]
HuH.7 VNN2
Mean 7.15
Standard deviation 2.5
Values 5.4 10 6
[103]
SNU475 VNN2
Mean 0.0454
Standard deviation 0.021
Values 0.06 0.03
[104]
THLE VNN2
Mean 1.15
Standard deviation 0.19
Values 1.3 1
[105]
liver VNN2
Mean 2.36
Standard deviation 0.89
Values 2.9 1.3 2 3.3
[106]
ref_hepatocyte BCAT1
Mean 1.1
Standard deviation 1.6
Values 4 0.11 0.078 0.91 0.46
[107]
HepG2 BCAT1
Mean 26.7
Standard deviation 1
Values 27 26
[108]
HepG2.C3A BCAT1
Mean 20
Standard deviation 6.4
Values 25 16
[109]
HuH.7 BCAT1
Mean 100
Standard deviation 19
Values 1.2e+02 87 92
[110]
SNU475 BCAT1
Mean 37.8
Standard deviation 14
Values 48 28
[111]
THLE BCAT1
Mean 114
Standard deviation 20
Values 1.3e+02 99
[112]
liver BCAT1
Mean 1.62
Standard deviation 0.82
Values 2.5 0.59 1.4 2.1