KEGG_PANCREATIC_CANCER | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | CDC42 | Cell division control protein 42 homolog | [1] | -1.57[2] | -0.72[3] | -1.78[4] | -1.16[5] | -1.79[6] | -2.51[7] |
2 | RAC1 | Ras-related C3 botulinum toxin substrate 1 | [8] | -1.13[9] | -1.33[10] | -0.68[11] | -0.61[12] | -0.53[13] | -1.39[14] |
3 | AKT1 | RAC-alpha serine/threonine-protein kinase | [15] | -0.66[16] | -0.76[17] | -1.89[18] | -0.68[19] | -0.56[20] | -0.67[21] |
4 | RALB | Ras-related protein Ral-B | [22] | -1.97[23] | -1.86[24] | -2.75[25] | -1.96[26] | -2.19[27] | -2.41[28] |
5 | STAT3 | Signal transducer and activator of transcription 3 | [29] | -0.19[30] | -1.56[31] | -0.87[32] | -0.39[33] | -1.01[34] | 1.98[35] |
6 | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 | [36] | -1.67[37] | -1.87[38] | -1.34[39] | -1.17[40] | -0.57[41] | -1.62[42] |
7 | BCL2L1 | Bcl-2-like protein 1 | [43] | 1.40[44] | 0.92[45] | 1.82[46] | -1.24[47] | -0.76[48] | -1.24[49] |
8 | CCND1 | G1/S-specific cyclin-D1 | [50] | 2.31[51] | -0.06[52] | 0.72[53] | 1.25[54] | -0.13[55] | 0.63[56] |
9 | IKBKG | NF-kappa-B essential modulator | [57] | -1.63[58] | -1.35[59] | -3.65[60] | -1.48[61] | -2.59[62] | -1.03[63] |
10 | RALA | Ras-related protein Ral-A | [64] | -1.93[65] | -1.06[66] | -0.94[67] | -1.20[68] | -0.81[69] | -2.16[70] |
11 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | [71] | -0.81[72] | -1.60[73] | -0.55[74] | 1.90[75] | -0.27[76] | 0.52[77] |
12 | CDK4 | Cyclin-dependent kinase 4 | [78] | 0.59[79] | 1.30[80] | 0.88[81] | -0.45[82] | 0.30[83] | -1.26[84] |
13 | BAD | Bcl2-associated agonist of cell death | [85] | -2.41[86] | -2.15[87] | -3.15[88] | -1.69[89] | -1.19[90] | -1.85[91] |
14 | RELA | Transcription factor p65 | [92] | -0.61[93] | -0.98[94] | -0.90[95] | -0.68[96] | -0.68[97] | -1.31[98] |
15 | RAF1 | RAF proto-oncogene serine/threonine-protein kinase | [99] | -0.80[100] | -0.27[101] | 0.95[102] | -0.81[103] | 0.15[104] | 0.67[105] |
16 | VEGFA | Vascular endothelial growth factor A | [106] | 0.48[107] | 1.95[108] | 0.49[109] | -0.19[110] | 0.62[111] | 0.35[112] |
17 | JAK1 | Tyrosine-protein kinase JAK1 | [113] | -0.23[114] | -0.61[115] | -0.48[116] | 0.00[117] | 0.74[118] | 1.10[119] |
18 | RALBP1 | RalA-binding protein 1 | [120] | -0.84[121] | -0.29[122] | 0.67[123] | 0.19[124] | -0.31[125] | -0.45[126] |
19 | ARAF | Serine/threonine-protein kinase A-Raf | [127] | -1.20[128] | -1.37[129] | -1.15[130] | -0.72[131] | -0.59[132] | 0.45[133] |
20 | TGFBR2 | TGF-beta receptor type-2 | [134] | 2.08[135] | 1.67[136] | 1.28[137] | 0.44[138] | 2.25[139] | 1.08[140] |
21 | MAPK1 | Mitogen-activated protein kinase 1 | [141] | 0.97[142] | 1.24[143] | 1.01[144] | 1.22[145] | 0.97[146] | 1.35[147] |
22 | AKT2 | RAC-beta serine/threonine-protein kinase | [148] | 0.22[149] | 0.62[150] | 0.70[151] | 0.23[152] | 0.12[153] | 0.70[154] |
23 | KRAS | GTPase KRas | [155] | -1.25[156] | -1.15[157] | 0.40[158] | 0.17[159] | -0.07[160] | 0.25[161] |
24 | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha | [162] | -1.21[163] | -0.96[164] | 0.07[165] | 1.44[166] | 1.04[167] | 2.57[168] |
25 | MAPK8 | Mitogen-activated protein kinase 8 | [169] | -2.18[170] | -0.64[171] | -1.83[172] | -1.53[173] | -1.58[174] | -0.94[175] |
26 | ERBB2 | Receptor tyrosine-protein kinase erbB-2 | [176] | 1.63[177] | 0.58[178] | 1.70[179] | 0.63[180] | 0.33[181] | -0.27[182] |
27 | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | [183] | -0.07[184] | -0.26[185] | -0.53[186] | -0.88[187] | 0.13[188] | 0.02[189] |
28 | SMAD3 | Mothers against decapentaplegic homolog 3 | [190] | 1.19[191] | 0.72[192] | 0.89[193] | 1.17[194] | 2.15[195] | -0.21[196] |
29 | EGFR | Epidermal growth factor receptor | [197] | -1.44[198] | -1.68[199] | 1.15[200] | -0.19[201] | 0.52[202] | 2.23[203] |
30 | TP53 | Cellular tumor antigen p53 | [204] | 0.90[205] | 0.59[206] | 1.30[207] | 0.66[208] | 0.43[209] | -0.47[210] |
31 | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta | [211] | 1.13[212] | 1.49[213] | 2.04[214] | 0.08[215] | 0.74[216] | -0.72[217] |
32 | VEGFB | Vascular endothelial growth factor B | [218] | -0.79[219] | -0.85[220] | -0.86[221] | 0.12[222] | -0.08[223] | -2.14[224] |
33 | RAD51 | DNA repair protein RAD51 homolog 1 | [225] | -0.99[226] | -1.05[227] | -1.00[228] | -0.81[229] | -0.75[230] | -4.37[231] |
34 | TGFBR1 | TGF-beta receptor type-1 | [232] | -0.41[233] | -0.05[234] | -0.61[235] | -0.29[236] | 0.92[237] | 0.91[238] |
35 | MAPK9 | Mitogen-activated protein kinase 9 | [239] | 0.49[240] | 0.84[241] | 0.85[242] | 1.09[243] | 0.64[244] | 0.08[245] |
36 | MAPK3 | Mitogen-activated protein kinase 3 | [246] | 1.11[247] | 1.29[248] | 1.27[249] | -0.20[250] | -0.09[251] | -1.47[252] |
37 | CDK6 | Cyclin-dependent kinase 6 | [253] | 1.31[254] | 2.14[255] | 0.48[256] | 0.29[257] | 1.19[258] | 1.65[259] |
38 | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha | [260] | 0.16[261] | 1.51[262] | 1.42[263] | 0.02[264] | 0.93[265] | 1.09[266] |
39 | RAC2 | Ras-related C3 botulinum toxin substrate 2 | [267] | -2.45[268] | -8.31[269] | -8.97[270] | -2.02[271] | 1.88[272] | -1.66[273] |
40 | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta | [274] | -0.22[275] | -0.03[276] | 0.02[277] | -0.37[278] | -0.18[279] | 0.76[280] |
41 | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 0.47[281] | 1.11[282] | 1.22[283] | 0.42[284] | 0.68[285] | 0.73[286] | |
42 | SMAD4 | Mothers against decapentaplegic homolog 4 | [287] | 0.65[288] | 1.41[289] | 1.33[290] | 1.28[291] | 1.75[292] | 2.36[293] |
43 | TGFB2 | Transforming growth factor beta-2 | [294] | -5.03[295] | -7.43[296] | -1.68[297] | 2.83[298] | 1.53[299] | -3.20[300] |
44 | RB1 | Retinoblastoma-associated protein | [301] | 0.48[302] | 1.11[303] | 1.62[304] | 1.65[305] | 2.07[306] | 1.05[307] |
45 | RAC3 | Ras-related C3 botulinum toxin substrate 3 | [308] | -1.11[309] | 2.08[310] | 0.86[311] | -0.52[312] | -1.90[313] | -3.90[314] |
46 | CASP9 | Caspase-9 | [315] | -0.58[316] | 0.51[317] | -0.43[318] | -0.38[319] | -0.97[320] | -0.96[321] |
47 | SMAD2 | Mothers against decapentaplegic homolog 2 | [322] | 1.28[323] | 1.67[324] | 1.11[325] | 1.75[326] | 2.04[327] | 2.14[328] |
48 | E2F1 | Transcription factor E2F1 | [329] | 1.21[330] | 1.19[331] | 1.27[332] | 1.24[333] | 1.77[334] | -4.04[335] |
49 | TGFB1 | Transforming growth factor beta-1 | [336] | 2.73[337] | 1.82[338] | -0.98[339] | 3.21[340] | 2.54[341] | -1.66[342] |
50 | E2F3 | Transcription factor E2F3 | [343] | 0.97[344] | 0.94[345] | 0.14[346] | 2.00[347] | 1.55[348] | -0.59[349] |
51 | PLD1 | Phospholipase D1 | [350] | 1.68[351] | 2.52[352] | 2.96[353] | 0.42[354] | 1.11[355] | 1.63[356] |
52 | TGFA | Protransforming growth factor alpha | [357] | 1.05[358] | 2.24[359] | -8.86[360] | -1.59[361] | -2.72[362] | -0.82[363] |
53 | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | -1.12[364] | 0.65[365] | 0.78[366] | 0.50[367] | 0.80[368] | 1.49[369] | |
54 | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 1.15[370] | 2.36[371] | -1.50[372] | -0.35[373] | 0.52[374] | -0.13[375] | |
55 | TGFB3 | Transforming growth factor beta-3 | [376] | -2.28[377] | -3.03[378] | -3.32[379] | -0.46[380] | -1.42[381] | 0.03[382] |
56 | BRAF | Serine/threonine-protein kinase B-raf | [383] | -0.49[384] | -0.63[385] | 1.35[386] | 0.11[387] | -0.10[388] | 1.43[389] |
57 | PGF | Placenta growth factor | [390] | 0.85[391] | 1.74[392] | 1.49[393] | -1.75[394] | 0.02[395] | -1.05[396] |
58 | RALGDS | Ral guanine nucleotide dissociation stimulator | [397] | 2.31[398] | 2.09[399] | 0.83[400] | 2.15[401] | 1.82[402] | 0.85[403] |
59 | ARHGEF6 | Rho guanine nucleotide exchange factor 6 | [404] | -6.76[405] | -4.38[406] | -5.05[407] | 2.60[408] | 1.22[409] | 2.71[410] |
60 | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma | [411] | 0.98[412] | 1.12[413] | 1.91[414] | 2.54[415] | 1.66[416] | 2.25[417] |
61 | AKT3 | RAC-gamma serine/threonine-protein kinase | [418] | -2.58[419] | -5.01[420] | -4.38[421] | 5.21[422] | 4.27[423] | 3.18[424] |
62 | PIK3R5 | Phosphoinositide 3-kinase regulatory subunit 5 | [425] | -7.91[426] | [427] | -3.20[428] | -4.55[429] | -4.11[430] | 1.91[431] |
63 | CDKN2A | Cyclin-dependent kinase inhibitor 2A | [432] | 3.34[433] | 1.24[434] | 4.59[435] | 4.58[436] | 6.46[437] | -2.58[438] |
64 | E2F2 | Transcription factor E2F2 | [439] | 3.50[440] | 4.53[441] | 3.99[442] | 3.42[443] | 3.85[444] | 0.99[445] |
65 | BRCA2 | Breast cancer type 2 susceptibility protein | [446] | 2.06[447] | 4.68[448] | 4.80[449] | 3.84[450] | 4.10[451] | 3.01[452] |
66 | PIK3CG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | [453] | [454] | [455] | 0.71[456] | -4.07[457] | 3.67[458] | |
67 | VEGFC | Vascular endothelial growth factor C | [459] | -1.17[460] | -4.14[461] | -5.11[462] | 2.98[463] | 6.72[464] | 2.86[465] |
68 | EGF | Pro-epidermal growth factor | [466] | 1.23[467] | 3.15[468] | 6.71[469] | 8.40[470] | 5.91[471] | 1.15[472] |
69 | MAPK10 | Mitogen-activated protein kinase 10 | [473] | -2.22[474] | [475] | [476] | 8.28[477] | 4.11[478] | 6.82[479] |
70 | VEGFD | Vascular endothelial growth factor D | [480] | [481] | [482] | [483] | [484] | [485] | [486] |