KEGG_MTOR_SIGNALING_PATHWAY Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 RPS6 40S ribosomal protein S6 [1] [2] [3] [4] [5] [6] [7]
2 EIF4B Eukaryotic translation initiation factor 4B [8] 1.79[9] 2.36[10] 2.62[11] 1.00[12] 1.09[13] 1.14[14]
3 RHEB GTP-binding protein Rheb [15] -0.75[16] -0.83[17] -0.86[18] 0.02[19] -0.14[20] -0.01[21]
4 EIF4E2 Eukaryotic translation initiation factor 4E type 2 [22] -1.37[23] -2.06[24] -1.67[25] -1.19[26] -1.76[27] -1.32[28]
5 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 [29] 0.20[30] -0.77[31] -0.12[32] -2.18[33] -0.91[34] -0.51[35]
6 AKT1 RAC-alpha serine/threonine-protein kinase [36] 1.27[37] 0.39[38] -0.64[39] 1.07[40] 0.82[41] 0.84[42]
7 DDIT4 DNA damage-inducible transcript 4 protein [43] 2.05[44] 2.06[45] 0.63[46] -0.97[47] 1.73[48] 0.34[49]
8 HIF1A Hypoxia-inducible factor 1-alpha [50] 1.04[51] 0.05[52] 0.90[53] 3.41[54] 3.51[55] 0.28[56]
9 IGF1 Insulin-like growth factor I [57] -7.23[58] -8.82[59] -6.98[60] -0.42[61] -8.52[62] 2.01[63]
10 RPS6KB2 Ribosomal protein S6 kinase beta-2 [64] [65] [66] [67] [68] [69] [70]
11 VEGFA Vascular endothelial growth factor A [71] 2.41[72] 3.09[73] 1.74[74] 1.56[75] 2.00[76] 1.87[77]
12 EIF4E Eukaryotic translation initiation factor 4E [78] 1.33[79] 1.51[80] 0.92[81] 0.85[82] 1.60[83] 1.26[84]
13 CAB39 Calcium-binding protein 39 [85] 0.70[86] 0.42[87] 0.86[88] 1.33[89] 1.28[90] 1.15[91]
14 STK11 Serine/threonine-protein kinase STK11 [92] 1.11[93] 0.40[94] 0.69[95] 0.41[96] 0.49[97] 0.22[98]
15 MAPK1 Mitogen-activated protein kinase 1 [99] 2.90[100] 2.39[101] 2.26[102] 2.97[103] 2.34[104] 2.86[105]
16 AKT2 RAC-beta serine/threonine-protein kinase [106] 2.15[107] 1.77[108] 1.95[109] 1.98[110] 1.50[111] 2.22[112]
17 MLST8 Target of rapamycin complex subunit LST8 [113] 1.02[114] 0.69[115] 1.11[116] 0.14[117] 0.22[118] 0.52[119]
18 RPS6KA3 Ribosomal protein S6 kinase alpha-3 [120] [121] [122] [123] [124] [125] [126]
19 PRKAA1 5'-AMP-activated protein kinase catalytic subunit alpha-1 [127] 1.11[128] 1.74[129] 3.30[130] 2.58[131] 2.58[132] 3.15[133]
20 PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha [134] 0.72[135] 0.18[136] 1.32[137] 3.19[138] 2.41[139] 4.09[140]
21 PIK3R2 Phosphatidylinositol 3-kinase regulatory subunit beta [141] 3.07[142] 2.64[143] 3.29[144] 1.83[145] 2.11[146] 0.80[147]
22 VEGFB Vascular endothelial growth factor B [148] 1.14[149] 0.30[150] 0.39[151] 1.87[152] 1.29[153] -0.63[154]
23 RPS6KA1 Ribosomal protein S6 kinase alpha-1 [155] [156] [157] [158] [159] [160] [161]
24 MAPK3 Mitogen-activated protein kinase 3 [162] 3.04[163] 2.43[164] 2.52[165] 1.54[166] 1.29[167] 0.05[168]
25 PDPK1 3-phosphoinositide-dependent protein kinase 1 [169] 3.52[170] 4.06[171] 2.82[172] 2.56[173] 2.68[174] 3.59[175]
26 ULK3 Serine/threonine-protein kinase ULK3 [176] 1.40[177] 1.23[178] 0.59[179] 1.31[180] 1.42[181] 2.74[182]
27 MTOR Serine/threonine-protein kinase mTOR [183] 3.73[184] 4.09[185] 3.70[186] 3.80[187] 3.61[188] 4.54[189]
28 TSC2 Tuberin [190] 3.01[191] 1.88[192] 2.61[193] 2.32[194] 2.57[195] 3.17[196]
29 ULK1 Serine/threonine-protein kinase ULK1 [197] 2.50[198] 2.13[199] 3.38[200] 3.09[201] 2.17[202] 2.98[203]
30 RPS6KB1 Ribosomal protein S6 kinase beta-1 [204] [205] [206] [207] [208] [209] [210]
31 PIK3CB Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 2.40[211] 2.26[212] 2.47[213] 2.17[214] 2.05[215] 2.24[216]
32 STRADA STE20-related kinase adapter protein alpha [217] 2.15[218] 1.59[219] 1.44[220] 2.20[221] 1.72[222] 1.35[223]
33 RPTOR Regulatory-associated protein of mTOR [224] 4.28[225] 2.86[226] 3.01[227] 2.97[228] 2.93[229] 3.42[230]
34 PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 0.81[231] 1.80[232] 2.03[233] 2.25[234] 2.18[235] 3.00[236]
35 PIK3CD Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 3.08[237] 3.51[238] -0.25[239] 1.40[240] 1.89[241] 1.38[242]
36 TSC1 Hamartin [243] 3.08[244] 3.09[245] 3.28[246] 3.18[247] 3.11[248] 3.84[249]
37 RICTOR Rapamycin-insensitive companion of mTOR [250] 1.92[251] 3.35[252] 4.07[253] 3.48[254] 3.40[255] 4.60[256]
38 RPS6KA2 Ribosomal protein S6 kinase alpha-2 [257] [258] [259] [260] [261] [262] [263]
39 CAB39L Calcium-binding protein 39-like [264] 0.69[265] 0.55[266] 1.26[267] 0.28[268] 1.14[269] 1.63[270]
40 BRAF Serine/threonine-protein kinase B-raf [271] 1.44[272] 0.51[273] 2.60[274] 1.86[275] 1.28[276] 2.94[277]
41 PGF Placenta growth factor [278] 2.78[279] 2.89[280] 2.74[281] 0.00[282] 1.40[283] 0.46[284]
42 PRKAA2 5'-AMP-activated protein kinase catalytic subunit alpha-2 [285] 4.22[286] 4.02[287] 4.10[288] 4.16[289] 1.93[290] 2.94[291]
43 ULK2 Serine/threonine-protein kinase ULK2 [292] -1.91[293] -1.59[294] 1.38[295] 4.41[296] 3.44[297] 3.49[298]
44 PIK3R3 Phosphatidylinositol 3-kinase regulatory subunit gamma [299] 2.91[300] 2.27[301] 3.16[302] 4.29[303] 3.03[304] 3.76[305]
45 AKT3 RAC-gamma serine/threonine-protein kinase [306] -0.65[307] -3.86[308] -3.13[309] 6.96[310] 5.64[311] 4.69[312]
46 PIK3R5 Phosphoinositide 3-kinase regulatory subunit 5 [313] -5.98[314] [315] -1.95[316] -2.80[317] -2.73[318] 3.42[319]
47 RPS6KA6 Ribosomal protein S6 kinase alpha-6 [320] [321] [322] [323] [324] [325] [326]
48 PIK3CG Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform [327] [328] [329] 2.46[330] -2.70[331] 5.18[332]
49 VEGFC Vascular endothelial growth factor C [333] 0.76[334] -2.99[335] -3.85[336] 4.73[337] 8.09[338] 4.37[339]
50 EIF4E1B Eukaryotic translation initiation factor 4E type 1B [340] [341] [342] [343] [344] [345] [346]
51 INS Insulin [347] [348] [349] [350] [351] [352] [353]
52 VEGFD Vascular endothelial growth factor D [354] [355] [356] [357] [358] [359] [360]
[1]
ref_hepatocyte RPS6
Mean 819
Standard deviation 2.5e+02
Values 6.5e+02 6.1e+02 1.2e+03 9e+02 7.2e+02
[2]
HepG2 RPS6
Missing
[3]
HepG2.C3A RPS6
Missing
[4]
HuH.7 RPS6
Missing
[5]
SNU475 RPS6
Missing
[6]
THLE RPS6
Missing
[7]
liver RPS6
Missing
[8]
ref_hepatocyte EIF4B
Mean 76.3
Standard deviation 32
Values 1.2e+02 82 49 86 43
[9]
HepG2 EIF4B
Mean 255
Standard deviation 11
Values 2.6e+02 2.5e+02
[10]
HepG2.C3A EIF4B
Mean 530
Standard deviation 1.8e+02
Values 6.6e+02 4e+02
[11]
HuH.7 EIF4B
Mean 590
Standard deviation 80
Values 5.6e+02 6.8e+02 5.3e+02
[12]
SNU475 EIF4B
Mean 129
Standard deviation 20
Values 1.4e+02 1.1e+02
[13]
THLE EIF4B
Mean 186
Standard deviation 19
Values 1.7e+02 2e+02
[14]
liver EIF4B
Mean 113
Standard deviation 68
Values 1.9e+02 62 51 1.5e+02
[15]
ref_hepatocyte RHEB
Mean 67.3
Standard deviation 38
Values 64 96 29 1.1e+02 33
[16]
HepG2 RHEB
Mean 38.6
Standard deviation 1.7
Values 40 37
[17]
HepG2.C3A RHEB
Mean 51.2
Standard deviation 9.4
Values 45 58
[18]
HuH.7 RHEB
Mean 46.6
Standard deviation 5.3
Values 44 44 53
[19]
SNU475 RHEB
Mean 57.5
Standard deviation 1.9
Values 59 56
[20]
THLE RHEB
Mean 69.7
Standard deviation 5.7
Values 66 74
[21]
liver RHEB
Mean 44.9
Standard deviation 28
Values 25 77 59 18
[22]
ref_hepatocyte EIF4E2
Mean 49.1
Standard deviation 31
Values 28 1e+02 34 47 35
[23]
HepG2 EIF4E2
Mean 18.3
Standard deviation 1.3
Values 17 19
[24]
HepG2.C3A EIF4E2
Mean 15.9
Standard deviation 3
Values 14 18
[25]
HuH.7 EIF4E2
Mean 19.4
Standard deviation 4.2
Values 23 15 21
[26]
SNU475 EIF4E2
Mean 18.2
Standard deviation 3.3
Values 21 16
[27]
THLE EIF4E2
Mean 16.6
Standard deviation 2.4
Values 15 18
[28]
liver EIF4E2
Mean 13.2
Standard deviation 7.8
Values 7.2 18 22 5.9
[29]
ref_hepatocyte EIF4EBP1
Mean 48.7
Standard deviation 38
Values 11 35 87 90 20
[30]
HepG2 EIF4EBP1
Mean 54.1
Standard deviation 26
Values 72 36
[31]
HepG2.C3A EIF4EBP1
Mean 38.6
Standard deviation 15
Values 49 28
[32]
HuH.7 EIF4EBP1
Mean 56.5
Standard deviation 22
Values 64 32 73
[33]
SNU475 EIF4EBP1
Mean 9.08
Standard deviation 1.3
Values 8.2 10
[34]
THLE EIF4EBP1
Mean 29.8
Standard deviation 5
Values 33 26
[35]
liver EIF4EBP1
Mean 22.9
Standard deviation 28
Values 3.1 62 22 4.4
[36]
ref_hepatocyte AKT1
Mean 37.6
Standard deviation 15
Values 55 50 31 19 32
[37]
HepG2 AKT1
Mean 87.8
Standard deviation 2.3
Values 89 86
[38]
HepG2.C3A AKT1
Mean 66.6
Standard deviation 2.4
Values 65 68
[39]
HuH.7 AKT1
Mean 30.2
Standard deviation 6.6
Values 33 23 35
[40]
SNU475 AKT1
Mean 66.6
Standard deviation 14
Values 76 57
[41]
THLE AKT1
Mean 75.8
Standard deviation 6.1
Values 72 80
[42]
liver AKT1
Mean 45.1
Standard deviation 25
Values 48 34 20 79
[43]
ref_hepatocyte DDIT4
Mean 32.1
Standard deviation 28
Values 9.8 25 77 41 8
[44]
HepG2 DDIT4
Mean 128
Standard deviation 49
Values 1.6e+02 93
[45]
HepG2.C3A DDIT4
Mean 181
Standard deviation 70
Values 2.3e+02 1.3e+02
[46]
HuH.7 DDIT4
Mean 62.5
Standard deviation 14
Values 60 50 77
[47]
SNU475 DDIT4
Mean 13.9
Standard deviation 1.7
Values 13 15
[48]
THLE DDIT4
Mean 122
Standard deviation 9.8
Values 1.3e+02 1.1e+02
[49]
liver DDIT4
Mean 27.2
Standard deviation 17
Values 19 50 28 12
[50]
ref_hepatocyte HIF1A
Mean 26.5
Standard deviation 22
Values 27 61 8.1 30 5.8
[51]
HepG2 HIF1A
Mean 52.5
Standard deviation 22
Values 37 68
[52]
HepG2.C3A HIF1A
Mean 37.2
Standard deviation 10
Values 30 44
[53]
HuH.7 HIF1A
Mean 62
Standard deviation 17
Values 81 55 49
[54]
SNU475 HIF1A
Mean 237
Standard deviation 65
Values 2.8e+02 1.9e+02
[55]
THLE HIF1A
Mean 346
Standard deviation 60
Values 3.9e+02 3e+02
[56]
liver HIF1A
Mean 21.5
Standard deviation 8.5
Values 25 12 18 31
[57]
ref_hepatocyte IGF1
Mean 17.2
Standard deviation 16
Values 0 18 24 5 39
[58]
HepG2 IGF1
Mean 0.111
Standard deviation 0.0052
Values 0.11 0.11
[59]
HepG2.C3A IGF1
Mean 0.0516
Standard deviation 0.018
Values 0.039 0.064
[60]
HuH.7 IGF1
Mean 0.171
Standard deviation 0.058
Values 0.11 0.22 0.19
[61]
SNU475 IGF1
Mean 10.9
Standard deviation 5.6
Values 15 6.9
[62]
THLE IGF1
Mean 0.0535
Standard deviation 0.008
Values 0.059 0.048
[63]
liver IGF1
Mean 46.3
Standard deviation 31
Values 24 92 31 39
[64]
ref_hepatocyte RPS6KB2
Mean 17
Standard deviation 4.8
Values 17 25 15 15 13
[65]
HepG2 RPS6KB2
Missing
[66]
HepG2.C3A RPS6KB2
Missing
[67]
HuH.7 RPS6KB2
Missing
[68]
SNU475 RPS6KB2
Missing
[69]
THLE RPS6KB2
Missing
[70]
liver RPS6KB2
Missing
[71]
ref_hepatocyte VEGFA
Mean 15.4
Standard deviation 8.3
Values 12 5.2 22 12 25
[72]
HepG2 VEGFA
Mean 78.9
Standard deviation 39
Values 1.1e+02 51
[73]
HepG2.C3A VEGFA
Mean 178
Standard deviation 91
Values 2.4e+02 1.1e+02
[74]
HuH.7 VEGFA
Mean 64.6
Standard deviation 7.4
Values 59 62 73
[75]
SNU475 VEGFA
Mean 38.2
Standard deviation 17
Values 26 50
[76]
THLE VEGFA
Mean 70.1
Standard deviation 17
Values 82 58
[77]
liver VEGFA
Mean 37.5
Standard deviation 27
Values 70 18 14 48
[78]
ref_hepatocyte EIF4E
Mean 15
Standard deviation 8.3
Values 17 28 7.1 13 10
[79]
HepG2 EIF4E
Mean 36.5
Standard deviation 7.8
Values 31 42
[80]
HepG2.C3A EIF4E
Mean 57.7
Standard deviation 21
Values 43 72
[81]
HuH.7 EIF4E
Mean 35.6
Standard deviation 9.2
Values 41 25 41
[82]
SNU475 EIF4E
Mean 22.8
Standard deviation 0.41
Values 23 22
[83]
THLE EIF4E
Mean 52.1
Standard deviation 2.8
Values 50 54
[84]
liver EIF4E
Mean 24
Standard deviation 12
Values 16 33 36 12
[85]
ref_hepatocyte CAB39
Mean 14.2
Standard deviation 6
Values 21 19 7.1 14 9.4
[86]
HepG2 CAB39
Mean 22.3
Standard deviation 3.9
Values 20 25
[87]
HepG2.C3A CAB39
Mean 25.8
Standard deviation 5
Values 22 29
[88]
HuH.7 CAB39
Mean 32.4
Standard deviation 8.1
Values 29 42 27
[89]
SNU475 CAB39
Mean 30.3
Standard deviation 2.8
Values 28 32
[90]
THLE CAB39
Mean 39.4
Standard deviation 2.2
Values 38 41
[91]
liver CAB39
Mean 21.1
Standard deviation 9.2
Values 32 16 12 25
[92]
ref_hepatocyte STK11
Mean 12.8
Standard deviation 5.7
Values 22 15 10 8 8.8
[93]
HepG2 STK11
Mean 26.5
Standard deviation 9.5
Values 33 20
[94]
HepG2.C3A STK11
Mean 22.8
Standard deviation 6.5
Values 27 18
[95]
HuH.7 STK11
Mean 25.9
Standard deviation 2.8
Values 26 23 29
[96]
SNU475 STK11
Mean 14.3
Standard deviation 1.5
Values 15 13
[97]
THLE STK11
Mean 20.5
Standard deviation 0.22
Values 21 20
[98]
liver STK11
Mean 9.97
Standard deviation 7.5
Values 17 3.6 3.3 16
[99]
ref_hepatocyte MAPK1
Mean 10.7
Standard deviation 3.7
Values 14 13 6.1 13 7.4
[100]
HepG2 MAPK1
Mean 77.6
Standard deviation 22
Values 62 93
[101]
HepG2.C3A MAPK1
Mean 76.1
Standard deviation 7.2
Values 71 81
[102]
HuH.7 MAPK1
Mean 64.8
Standard deviation 7.4
Values 73 60 61
[103]
SNU475 MAPK1
Mean 71.1
Standard deviation 8
Values 77 65
[104]
THLE MAPK1
Mean 62.4
Standard deviation 14
Values 53 72
[105]
liver MAPK1
Mean 52.3
Standard deviation 14
Values 68 39 41 61
[106]
ref_hepatocyte AKT2
Mean 10.6
Standard deviation 2.8
Values 7.2 8.4 13 11 14
[107]
HepG2 AKT2
Mean 45.6
Standard deviation 3.3
Values 48 43
[108]
HepG2.C3A AKT2
Mean 49.1
Standard deviation 8.9
Values 55 43
[109]
HuH.7 AKT2
Mean 51.5
Standard deviation 9.8
Values 59 41 55
[110]
SNU475 AKT2
Mean 35.3
Standard deviation 5.9
Values 39 31
[111]
THLE AKT2
Mean 34.2
Standard deviation 3.5
Values 32 37
[112]
liver AKT2
Mean 33
Standard deviation 9.4
Values 36 24 27 45
[113]
ref_hepatocyte MLST8
Mean 10
Standard deviation 3.8
Values 7 5.5 14 14 10
[114]
HepG2 MLST8
Mean 19.6
Standard deviation 1.4
Values 21 19
[115]
HepG2.C3A MLST8
Mean 22
Standard deviation 3.6
Values 24 19
[116]
HuH.7 MLST8
Mean 27.2
Standard deviation 3.6
Values 28 23 30
[117]
SNU475 MLST8
Mean 9.36
Standard deviation 0.84
Values 9.9 8.8
[118]
THLE MLST8
Mean 13.3
Standard deviation 1.9
Values 12 15
[119]
liver MLST8
Mean 9.64
Standard deviation 7.6
Values 2.5 17 15 3.8
[120]
ref_hepatocyte RPS6KA3
Mean 9.94
Standard deviation 10
Values 28 6.9 4.1 4.8 6.3
[121]
HepG2 RPS6KA3
Missing
[122]
HepG2.C3A RPS6KA3
Missing
[123]
HuH.7 RPS6KA3
Missing
[124]
SNU475 RPS6KA3
Missing
[125]
THLE RPS6KA3
Missing
[126]
liver RPS6KA3
Missing
[127]
ref_hepatocyte PRKAA1
Mean 8.04
Standard deviation 3.4
Values 5.4 7.6 7.2 6.1 14
[128]
HepG2 PRKAA1
Mean 16.8
Standard deviation 2.1
Values 15 18
[129]
HepG2.C3A PRKAA1
Mean 36.3
Standard deviation 5.5
Values 32 40
[130]
HuH.7 PRKAA1
Mean 99.5
Standard deviation 14
Values 1.1e+02 1e+02 84
[131]
SNU475 PRKAA1
Mean 40.7
Standard deviation 4.8
Values 44 37
[132]
THLE PRKAA1
Mean 55.1
Standard deviation 6.9
Values 60 50
[133]
liver PRKAA1
Mean 47.6
Standard deviation 7.3
Values 58 40 45 47
[134]
ref_hepatocyte PIK3R1
Mean 7.45
Standard deviation 3.9
Values 4.1 7.4 8.1 4.2 14
[135]
HepG2 PIK3R1
Mean 11.9
Standard deviation 3
Values 9.8 14
[136]
HepG2.C3A PIK3R1
Mean 11.5
Standard deviation 2.6
Values 9.6 13
[137]
HuH.7 PIK3R1
Mean 23.4
Standard deviation 8.6
Values 23 32 15
[138]
SNU475 PIK3R1
Mean 57.3
Standard deviation 32
Values 80 35
[139]
THLE PIK3R1
Mean 45.5
Standard deviation 1.5
Values 44 47
[140]
liver PIK3R1
Mean 84.8
Standard deviation 47
Values 1e+02 64 32 1.4e+02
[141]
ref_hepatocyte PIK3R2
Mean 5.25
Standard deviation 3.4
Values 11 3.2 4.9 3.1 3.8
[142]
HepG2 PIK3R2
Mean 42.5
Standard deviation 2.8
Values 44 41
[143]
HepG2.C3A PIK3R2
Mean 44.2
Standard deviation 13
Values 53 35
[144]
HuH.7 PIK3R2
Mean 64.7
Standard deviation 10
Values 75 55 64
[145]
SNU475 PIK3R2
Mean 15.7
Standard deviation 3.3
Values 18 13
[146]
THLE PIK3R2
Mean 26
Standard deviation 2.8
Values 24 28
[147]
liver PIK3R2
Mean 6.1
Standard deviation 1.7
Values 6 7.6 3.8 6.9
[148]
ref_hepatocyte VEGFB
Mean 5.17
Standard deviation 3.9
Values 4.6 0.9 11 2.7 6.4
[149]
HepG2 VEGFB
Mean 11
Standard deviation 3.1
Values 13 8.8
[150]
HepG2.C3A VEGFB
Mean 8.63
Standard deviation 2.7
Values 11 6.7
[151]
HuH.7 VEGFB
Mean 8.48
Standard deviation 0.47
Values 8.4 8.1 9
[152]
SNU475 VEGFB
Mean 15.9
Standard deviation 6.5
Values 21 11
[153]
THLE VEGFB
Mean 14.5
Standard deviation 2.1
Values 13 16
[154]
liver VEGFB
Mean 2.24
Standard deviation 1.9
Values 1.2 4.8 2.4 0.62
[155]
ref_hepatocyte RPS6KA1
Mean 4.78
Standard deviation 3.4
Values 10 5.6 2.9 3.5 1.5
[156]
HepG2 RPS6KA1
Missing
[157]
HepG2.C3A RPS6KA1
Missing
[158]
HuH.7 RPS6KA1
Missing
[159]
SNU475 RPS6KA1
Missing
[160]
THLE RPS6KA1
Missing
[161]
liver RPS6KA1
Missing
[162]
ref_hepatocyte MAPK3
Mean 4.16
Standard deviation 1.3
Values 5.1 2.8 6 3.6 3.3
[163]
HepG2 MAPK3
Mean 33.1
Standard deviation 5.2
Values 37 29
[164]
HepG2.C3A MAPK3
Mean 30.4
Standard deviation 12
Values 39 22
[165]
HuH.7 MAPK3
Mean 30
Standard deviation 4.8
Values 34 25 32
[166]
SNU475 MAPK3
Mean 10.2
Standard deviation 2.4
Values 12 8.5
[167]
THLE MAPK3
Mean 11.6
Standard deviation 1.1
Values 11 12
[168]
liver MAPK3
Mean 2.87
Standard deviation 2.4
Values 0.81 5 4.8 0.82
[169]
ref_hepatocyte PDPK1
Mean 3.54
Standard deviation 2
Values 6.9 3.4 1.8 3.6 2
[170]
HepG2 PDPK1
Mean 39.4
Standard deviation 5.6
Values 35 43
[171]
HepG2.C3A PDPK1
Mean 80.1
Standard deviation 13
Values 89 71
[172]
HuH.7 PDPK1
Mean 31.4
Standard deviation 4.5
Values 35 33 26
[173]
SNU475 PDPK1
Mean 17.6
Standard deviation 0.21
Values 17 18
[174]
THLE PDPK1
Mean 25.9
Standard deviation 4.6
Values 23 29
[175]
liver PDPK1
Mean 28.5
Standard deviation 5.1
Values 27 34 22 31
[176]
ref_hepatocyte ULK3
Mean 3.34
Standard deviation 1.3
Values 1.4 3 4.1 3.3 4.9
[177]
HepG2 ULK3
Mean 8.54
Standard deviation 0.31
Values 8.8 8.3
[178]
HepG2.C3A ULK3
Mean 10.6
Standard deviation 0.14
Values 11 10
[179]
HuH.7 ULK3
Mean 6.32
Standard deviation 2.1
Values 7 4 8
[180]
SNU475 ULK3
Mean 6.99
Standard deviation 1.2
Values 7.8 6.1
[181]
THLE ULK3
Mean 10.2
Standard deviation 1.4
Values 11 9.3
[182]
liver ULK3
Mean 15
Standard deviation 8.4
Values 7.3 26 16 10
[183]
ref_hepatocyte MTOR
Mean 3.34
Standard deviation 0.62
Values 2.6 3.1 3.5 4.3 3.2
[184]
HepG2 MTOR
Mean 42.7
Standard deviation 6.3
Values 38 47
[185]
HepG2.C3A MTOR
Mean 76.8
Standard deviation 17
Values 89 65
[186]
HuH.7 MTOR
Mean 54.5
Standard deviation 17
Values 73 50 41
[187]
SNU475 MTOR
Mean 39.4
Standard deviation 0.66
Values 39 40
[188]
THLE MTOR
Mean 46.6
Standard deviation 4.9
Values 43 50
[189]
liver MTOR
Mean 51.8
Standard deviation 18
Values 72 34 39 62
[190]
ref_hepatocyte TSC2
Mean 3.2
Standard deviation 0.13
Values 3.1 3.1 3.2 3.2 3.4
[191]
HepG2 TSC2
Mean 24.9
Standard deviation 3.4
Values 27 22
[192]
HepG2.C3A TSC2
Mean 16
Standard deviation 4.7
Values 19 13
[193]
HuH.7 TSC2
Mean 24.6
Standard deviation 4
Values 29 24 21
[194]
SNU475 TSC2
Mean 13.5
Standard deviation 5
Values 17 10
[195]
THLE TSC2
Mean 21.8
Standard deviation 1.7
Values 21 23
[196]
liver TSC2
Mean 19.2
Standard deviation 2.2
Values 19 17 18 22
[197]
ref_hepatocyte ULK1
Mean 3.19
Standard deviation 0.97
Values 2.2 2.6 4.6 3.8 2.7
[198]
HepG2 ULK1
Mean 17.5
Standard deviation 3
Values 20 15
[199]
HepG2.C3A ULK1
Mean 18.9
Standard deviation 12
Values 27 10
[200]
HuH.7 ULK1
Mean 41.8
Standard deviation 6.6
Values 38 49 38
[201]
SNU475 ULK1
Mean 23
Standard deviation 7.3
Values 28 18
[202]
THLE ULK1
Mean 16.5
Standard deviation 0.85
Values 16 17
[203]
liver ULK1
Mean 16.8
Standard deviation 11
Values 7.2 29 8.9 22
[204]
ref_hepatocyte RPS6KB1
Mean 3.19
Standard deviation 1.6
Values 5.1 4.9 2 1.9 2.1
[205]
HepG2 RPS6KB1
Missing
[206]
HepG2.C3A RPS6KB1
Missing
[207]
HuH.7 RPS6KB1
Missing
[208]
SNU475 RPS6KB1
Missing
[209]
THLE RPS6KB1
Missing
[210]
liver RPS6KB1
Missing
[211]
ref_hepatocyte PIK3CB
Mean 3.18
Standard deviation 1.5
Values 5.2 4.2 1.8 2.6 2.1
[212]
HepG2 PIK3CB
Mean 16.3
Standard deviation 2.1
Values 15 18
[213]
HepG2.C3A PIK3CB
Mean 20.6
Standard deviation 2.7
Values 23 19
[214]
HuH.7 PIK3CB
Mean 22.1
Standard deviation 2.1
Values 24 23 20
[215]
SNU475 PIK3CB
Mean 12.1
Standard deviation 2.7
Values 14 10
[216]
THLE PIK3CB
Mean 15.1
Standard deviation 0.94
Values 14 16
[217]
liver PIK3CB
Mean 10.1
Standard deviation 3.7
Values 15 6.4 7.9 11
[218]
ref_hepatocyte STRADA
Mean 2.3
Standard deviation 0.78
Values 2.2 1.1 2.9 2.2 3.1
[219]
HepG2 STRADA
Mean 9.85
Standard deviation 1.6
Values 8.7 11
[220]
HepG2.C3A STRADA
Mean 9.38
Standard deviation 0.76
Values 8.8 9.9
[221]
HuH.7 STRADA
Mean 7.84
Standard deviation 2.2
Values 8.7 5.3 9.5
[222]
SNU475 STRADA
Mean 8.92
Standard deviation 1.6
Values 10 7.8
[223]
THLE STRADA
Mean 8.66
Standard deviation 0.55
Values 8.3 9
[224]
liver STRADA
Mean 3.93
Standard deviation 2
Values 2.3 5.1 6.1 2.3
[225]
ref_hepatocyte RPTOR
Mean 1.96
Standard deviation 0.72
Values 2.5 2.4 1.1 2.6 1.2
[226]
HepG2 RPTOR
Mean 36.8
Standard deviation 1
Values 36 38
[227]
HepG2.C3A RPTOR
Mean 19.3
Standard deviation 0.98
Values 20 19
[228]
HuH.7 RPTOR
Mean 19.8
Standard deviation 7.4
Values 28 14 17
[229]
SNU475 RPTOR
Mean 13
Standard deviation 0.49
Values 13 13
[230]
THLE RPTOR
Mean 17.1
Standard deviation 3.1
Values 15 19
[231]
liver RPTOR
Mean 14.1
Standard deviation 7.6
Values 20 7.5 7.6 21
[232]
ref_hepatocyte PIK3CA
Mean 1.87
Standard deviation 0.73
Values 2.3 2.6 1.2 2.3 0.94
[233]
HepG2 PIK3CA
Mean 3.17
Standard deviation 1.6
Values 2.1 4.3
[234]
HepG2.C3A PIK3CA
Mean 8.78
Standard deviation 1.1
Values 8 9.6
[235]
HuH.7 PIK3CA
Mean 9.59
Standard deviation 2.4
Values 10 12 7
[236]
SNU475 PIK3CA
Mean 7.49
Standard deviation 0.93
Values 8.1 6.8
[237]
THLE PIK3CA
Mean 9.67
Standard deviation 0.66
Values 10 9.2
[238]
liver PIK3CA
Mean 9.99
Standard deviation 4.7
Values 15 6.1 6 13
[239]
ref_hepatocyte PIK3CD
Mean 1.86
Standard deviation 1.7
Values 4.1 0.94 0.38 3.3 0.66
[240]
HepG2 PIK3CD
Mean 15.2
Standard deviation 3.8
Values 18 13
[241]
HepG2.C3A PIK3CD
Mean 28.8
Standard deviation 2.6
Values 31 27
[242]
HuH.7 PIK3CD
Mean 1.97
Standard deviation 0.32
Values 2 2.3 1.6
[243]
SNU475 PIK3CD
Mean 4.15
Standard deviation 0.57
Values 4.6 3.7
[244]
THLE PIK3CD
Mean 7.91
Standard deviation 1.1
Values 7.1 8.7
[245]
liver PIK3CD
Mean 3.25
Standard deviation 1.3
Values 3 2.4 2.6 5.1
[246]
ref_hepatocyte TSC1
Mean 1.81
Standard deviation 0.96
Values 3.1 2.1 0.7 2.1 1.1
[247]
HepG2 TSC1
Mean 14.8
Standard deviation 1.6
Values 14 16
[248]
HepG2.C3A TSC1
Mean 20.9
Standard deviation 3.3
Values 23 19
[249]
HuH.7 TSC1
Mean 22.2
Standard deviation 4.3
Values 22 26 18
[250]
SNU475 TSC1
Mean 13.9
Standard deviation 2.8
Values 16 12
[251]
THLE TSC1
Mean 18
Standard deviation 3.2
Values 16 20
[252]
liver TSC1
Mean 17.4
Standard deviation 1.8
Values 20 17 16 17
[253]
ref_hepatocyte RICTOR
Mean 1.67
Standard deviation 0.88
Values 2.2 2.1 0.49 2.6 1
[254]
HepG2 RICTOR
Mean 6.11
Standard deviation 1
Values 5.4 6.8
[255]
HepG2.C3A RICTOR
Mean 23
Standard deviation 1
Values 22 24
[256]
HuH.7 RICTOR
Mean 35.2
Standard deviation 17
Values 31 54 21
[257]
SNU475 RICTOR
Mean 15.7
Standard deviation 0.97
Values 16 15
[258]
THLE RICTOR
Mean 20.3
Standard deviation 7.9
Values 26 15
[259]
liver RICTOR
Mean 27.1
Standard deviation 8.5
Values 35 24 17 33
[260]
ref_hepatocyte RPS6KA2
Mean 1.31
Standard deviation 0.89
Values 0 1.8 1.1 2.4 1.3
[261]
HepG2 RPS6KA2
Missing
[262]
HepG2.C3A RPS6KA2
Missing
[263]
HuH.7 RPS6KA2
Missing
[264]
SNU475 RPS6KA2
Missing
[265]
THLE RPS6KA2
Missing
[266]
liver RPS6KA2
Missing
[267]
ref_hepatocyte CAB39L
Mean 1.2
Standard deviation 0.24
Values 1.2 1.6 0.95 1.1 1.1
[268]
HepG2 CAB39L
Mean 1.88
Standard deviation 0.59
Values 1.5 2.3
[269]
HepG2.C3A CAB39L
Mean 2.38
Standard deviation 0.34
Values 2.1 2.6
[270]
HuH.7 CAB39L
Mean 3.63
Standard deviation 0.81
Values 4.5 3.5 2.9
[271]
SNU475 CAB39L
Mean 1.23
Standard deviation 0.012
Values 1.2 1.2
[272]
THLE CAB39L
Mean 3.03
Standard deviation 0.77
Values 2.5 3.6
[273]
liver CAB39L
Mean 2.49
Standard deviation 0.25
Values 2.4 2.3 2.4 2.8
[274]
ref_hepatocyte BRAF
Mean 1.07
Standard deviation 0.72
Values 0.56 1.2 0.67 2.3 0.67
[275]
HepG2 BRAF
Mean 2.8
Standard deviation 0.62
Values 2.4 3.2
[276]
HepG2.C3A BRAF
Mean 2.07
Standard deviation 0.66
Values 1.6 2.5
[277]
HuH.7 BRAF
Mean 8.12
Standard deviation 5.8
Values 6.4 15 3.4
[278]
SNU475 BRAF
Mean 3.28
Standard deviation 0.16
Values 3.2 3.4
[279]
THLE BRAF
Mean 2.97
Standard deviation 0.38
Values 2.7 3.2
[280]
liver BRAF
Mean 5.48
Standard deviation 2.9
Values 8 3.1 2.9 7.9
[281]
ref_hepatocyte PGF
Mean 0.983
Standard deviation 1.7
Values 4.1 0.19 0.22 0.34 0.089
[282]
HepG2 PGF
Mean 6.53
Standard deviation 2.4
Values 8.2 4.8
[283]
HepG2.C3A PGF
Mean 9.87
Standard deviation 4.2
Values 13 6.9
[284]
HuH.7 PGF
Mean 8.24
Standard deviation 1.3
Values 7.6 7.4 9.8
[285]
SNU475 PGF
Mean 0.828
Standard deviation 0.62
Values 0.39 1.3
[286]
THLE PGF
Mean 2.97
Standard deviation 0.17
Values 3.1 2.8
[287]
liver PGF
Mean 0.907
Standard deviation 0.89
Values 0.13 2.2 0.46 0.87
[288]
ref_hepatocyte PRKAA2
Mean 0.754
Standard deviation 0.84
Values 2 1.2 0.1 0.23 0.24
[289]
HepG2 PRKAA2
Mean 13.6
Standard deviation 4
Values 11 16
[290]
HepG2.C3A PRKAA2
Mean 16.6
Standard deviation 1.4
Values 16 18
[291]
HuH.7 PRKAA2
Mean 16.2
Standard deviation 6.6
Values 16 23 9.7
[292]
SNU475 PRKAA2
Mean 11.4
Standard deviation 0.77
Values 12 11
[293]
THLE PRKAA2
Mean 3.29
Standard deviation 0.6
Values 3.7 2.9
[294]
liver PRKAA2
Mean 3.87
Standard deviation 1.2
Values 4 4.3 2.2 5
[295]
ref_hepatocyte ULK2
Mean 0.556
Standard deviation 0.3
Values 0.026 0.66 0.65 0.76 0.69
[296]
HepG2 ULK2
Mean 0.143
Standard deviation 0.033
Values 0.17 0.12
[297]
HepG2.C3A ULK2
Mean 0.25
Standard deviation 0.01
Values 0.24 0.26
[298]
HuH.7 ULK2
Mean 1.82
Standard deviation 0.22
Values 1.7 2.1 1.7
[299]
SNU475 ULK2
Mean 9.97
Standard deviation 5.4
Values 14 6.1
[300]
THLE ULK2
Mean 6.93
Standard deviation 0.73
Values 7.4 6.4
[301]
liver ULK2
Mean 4.19
Standard deviation 1.7
Values 6.1 2.3 3.3 5.1
[302]
ref_hepatocyte PIK3R3
Mean 0.405
Standard deviation 0.3
Values 0.52 0.81 0.078 0.47 0.15
[303]
HepG2 PIK3R3
Mean 2.95
Standard deviation 2.5
Values 1.2 4.7
[304]
HepG2.C3A PIK3R3
Mean 2.65
Standard deviation 1.6
Values 1.5 3.8
[305]
HuH.7 PIK3R3
Mean 4.56
Standard deviation 1.3
Values 5.7 3.1 5
[306]
SNU475 PIK3R3
Mean 6.68
Standard deviation 0.22
Values 6.5 6.8
[307]
THLE PIK3R3
Mean 3.8
Standard deviation 0.9
Values 3.2 4.4
[308]
liver PIK3R3
Mean 3.68
Standard deviation 0.27
Values 3.8 3.7 3.3 4
[309]
ref_hepatocyte AKT3
Mean 0.387
Standard deviation 0.32
Values 0 0.53 0.16 0.83 0.41
[310]
HepG2 AKT3
Mean 0.238
Standard deviation 0.15
Values 0.34 0.13
[311]
HepG2.C3A AKT3
Mean 0.036
Standard deviation 0.0097
Values 0.029 0.043
[312]
HuH.7 AKT3
Mean 0.0557
Standard deviation 0.031
Values 0.049 0.09 0.028
[313]
SNU475 AKT3
Mean 40.8
Standard deviation 10
Values 48 34
[314]
THLE AKT3
Mean 22.1
Standard deviation 4.4
Values 25 19
[315]
liver AKT3
Mean 6.71
Standard deviation 4.9
Values 12 2.8 2.3 9.4
[316]
ref_hepatocyte PIK3R5
Mean 0.373
Standard deviation 0.52
Values 0 0 0.29 1.3 0.3
[317]
HepG2 PIK3R5
Mean 0.00573
Standard deviation 0.0081
Values 0.011 0
[318]
HepG2.C3A PIK3R5
Mean 0
Standard deviation 0
Values 0 0
[319]
HuH.7 PIK3R5
Mean 0.122
Standard deviation 0.035
Values 0.09 0.12 0.16
[320]
SNU475 PIK3R5
Mean 0.0452
Standard deviation 0.051
Values 0.0093 0.081
[321]
THLE PIK3R5
Mean 0.0642
Standard deviation 0.068
Values 0.11 0.016
[322]
liver PIK3R5
Mean 2.68
Standard deviation 0.95
Values 2.9 1.9 2 3.9
[323]
ref_hepatocyte RPS6KA6
Mean 0.219
Standard deviation 0.15
Values 0.11 0.36 0.043 0.4 0.18
[324]
HepG2 RPS6KA6
Missing
[325]
HepG2.C3A RPS6KA6
Missing
[326]
HuH.7 RPS6KA6
Missing
[327]
SNU475 RPS6KA6
Missing
[328]
THLE RPS6KA6
Missing
[329]
liver RPS6KA6
Missing
[330]
ref_hepatocyte PIK3CG
Mean 0.0637
Standard deviation 0.13
Values 0 0 0.026 0 0.29
[331]
HepG2 PIK3CG
Mean 0
Standard deviation 0
Values 0 0
[332]
HepG2.C3A PIK3CG
Mean 0
Standard deviation 0
Values 0 0
[333]
HuH.7 PIK3CG
Mean 0
Standard deviation 0
Values 0 0 0
[334]
SNU475 PIK3CG
Mean 0.296
Standard deviation 0.1
Values 0.22 0.37
[335]
THLE PIK3CG
Mean 0.0112
Standard deviation 0.00084
Values 0.012 0.011
[336]
liver PIK3CG
Mean 1.55
Standard deviation 0.43
Values 1.9 0.94 1.7 1.6
[337]
ref_hepatocyte VEGFC
Mean 0.0315
Standard deviation 0.043
Values 0 0 0 0.076 0.081
[338]
HepG2 VEGFC
Mean 0.0516
Standard deviation 0.073
Values 0.1 0
[339]
HepG2.C3A VEGFC
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[340]
HuH.7 VEGFC
Mean 0.00273
Standard deviation 0.0047
Values 0.0082 0 0
[341]
SNU475 VEGFC
Mean 0.706
Standard deviation 0.42
Values 0.41 1
[342]
THLE VEGFC
Mean 9.83
Standard deviation 0.041
Values 9.9 9.8
[343]
liver VEGFC
Mean 0.435
Standard deviation 0.18
Values 0.66 0.21 0.46 0.41
[344]
ref_hepatocyte EIF4E1B
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[345]
HepG2 EIF4E1B
Missing
[346]
HepG2.C3A EIF4E1B
Missing
[347]
HuH.7 EIF4E1B
Missing
[348]
SNU475 EIF4E1B
Missing
[349]
THLE EIF4E1B
Missing
[350]
liver EIF4E1B
Missing
[351]
ref_hepatocyte INS
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[352]
HepG2 INS
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[353]
HepG2.C3A INS
Mean 0
Standard deviation 0
Values 0 0
[354]
HuH.7 INS
Mean 0
Standard deviation 0
Values 0 0 0
[355]
SNU475 INS
Mean 0
Standard deviation 0
Values 0 0
[356]
THLE INS
Mean 0
Standard deviation 0
Values 0 0
[357]
liver INS
Mean 0.0838
Standard deviation 0.13
Values 0.057 0 0 0.28
[358]
ref_hepatocyte VEGFD
Missing
[359]
HepG2 VEGFD
Missing
[360]
HepG2.C3A VEGFD
Missing
[361]
HuH.7 VEGFD
Missing
[362]
SNU475 VEGFD
Missing
[363]
THLE VEGFD
Missing
[364]
liver VEGFD
Missing