KEGG_MISMATCH_REPAIR Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 SSBP1 Single-stranded DNA-binding protein, mitochondrial [1] -1.78[2] -2.36[3] -2.09[4] -2.27[5] -2.20[6] -1.26[7]
2 PCNA Proliferating cell nuclear antigen [8] 1.06[9] 0.79[10] -0.83[11] -0.45[12] -0.04[13] -2.41[14]
3 POLD2 DNA polymerase delta subunit 2 [15] -0.43[16] -0.51[17] -0.21[18] -1.10[19] -0.60[20] 0.54[21]
4 POLD4 DNA polymerase delta subunit 4 [22] -1.96[23] -2.56[24] -0.69[25] 1.21[26] -2.25[27] 0.19[28]
5 RPA2 Replication protein A 32 kDa subunit [29] -1.29[30] -1.47[31] -1.12[32] -0.97[33] -0.77[34] -1.73[35]
6 RFC4 Replication factor C subunit 4 [36] -0.80[37] -0.42[38] -0.05[39] -1.20[40] 0.26[41] -2.09[42]
7 MSH6 DNA mismatch repair protein Msh6 [43] 0.49[44] 0.72[45] 0.72[46] 0.67[47] 1.21[48] 0.96[49]
8 RFC1 Replication factor C subunit 1 [50] 0.31[51] 1.35[52] 1.52[53] 0.09[54] 1.06[55] 1.44[56]
9 RFC2 Replication factor C subunit 2 [57] -0.09[58] -0.49[59] -0.66[60] -0.05[61] 0.53[62] -0.11[63]
10 RPA1 Replication protein A 70 kDa DNA-binding subunit [64] 1.48[65] 0.97[66] 1.03[67] 1.62[68] 1.76[69] 0.67[70]
11 RPA3 Replication protein A 14 kDa subunit [71] -0.20[72] 0.35[73] 0.86[74] -1.13[75] -0.73[76] -0.03[77]
12 MLH1 DNA mismatch repair protein Mlh1 [78] 1.02[79] 0.89[80] 1.43[81] -0.09[82] 0.69[83] 1.09[84]
13 RFC5 Replication factor C subunit 5 [85] 0.30[86] 0.51[87] 0.49[88] 0.04[89] 0.69[90] -0.21[91]
14 PMS2 Mismatch repair endonuclease PMS2 [92] -1.24[93] -1.76[94] -1.07[95] -0.82[96] -1.01[97] -0.75[98]
15 MSH2 DNA mismatch repair protein Msh2 [99] 0.99[100] 2.03[101] 1.26[102] 1.91[103] 1.39[104] -0.03[105]
16 RFC3 Replication factor C subunit 3 [106] 1.35[107] 1.96[108] 1.89[109] 1.02[110] 1.74[111] -0.20[112]
17 LIG1 DNA ligase 1 [113] 1.80[114] 1.57[115] 1.99[116] 0.28[117] 1.14[118] 0.30[119]
18 POLD1 DNA polymerase delta catalytic subunit [120] 2.03[121] 2.00[122] 2.61[123] 1.59[124] 2.48[125] 1.33[126]
19 MSH3 DNA mismatch repair protein Msh3 [127] 0.92[128] 1.28[129] 0.85[130] 1.25[131] 1.26[132] 3.09[133]
20 POLD3 DNA polymerase delta subunit 3 [134] 1.34[135] 0.96[136] 1.73[137] 1.89[138] 2.49[139] 1.65[140]
21 MLH3 DNA mismatch repair protein Mlh3 [141] 1.46[142] 2.41[143] 1.40[144] 2.02[145] 1.78[146] 4.06[147]
22 EXO1 Exonuclease 1 [148] 2.08[149] 2.11[150] 3.07[151] 3.55[152] 2.95[153] -0.81[154]
23 RPA4 Replication protein A 30 kDa subunit [155] -5.04[156] -5.03[157] [158] -1.96[159] -1.85[160] 2.51[161]
[1]
ref_hepatocyte SSBP1
Mean 63.6
Standard deviation 29
Values 32 1.1e+02 63 52 60
[2]
HepG2 SSBP1
Mean 36.3
Standard deviation 0.23
Values 36 37
[3]
HepG2.C3A SSBP1
Mean 25.9
Standard deviation 10
Values 19 33
[4]
HuH.7 SSBP1
Mean 34.6
Standard deviation 14
Values 39 19 46
[5]
SNU475 SSBP1
Mean 28.4
Standard deviation 0.55
Values 29 28
[6]
THLE SSBP1
Mean 30.7
Standard deviation 4.1
Values 28 34
[7]
liver SSBP1
Mean 23.8
Standard deviation 20
Values 7.5 41 41 6.1
[8]
ref_hepatocyte PCNA
Mean 36
Standard deviation 33
Values 92 37 19 14 17
[9]
HepG2 PCNA
Mean 147
Standard deviation 54
Values 1.1e+02 1.9e+02
[10]
HepG2.C3A PCNA
Mean 130
Standard deviation 86
Values 69 1.9e+02
[11]
HuH.7 PCNA
Mean 46.8
Standard deviation 33
Values 53 10 76
[12]
SNU475 PCNA
Mean 56.8
Standard deviation 7.7
Values 51 62
[13]
THLE PCNA
Mean 77.4
Standard deviation 13
Values 68 86
[14]
liver PCNA
Mean 6.07
Standard deviation 2.5
Values 5.2 7.3 8.8 3
[15]
ref_hepatocyte POLD2
Mean 32.3
Standard deviation 18
Values 10 23 58 30 40
[16]
HepG2 POLD2
Mean 47
Standard deviation 5.6
Values 51 43
[17]
HepG2.C3A POLD2
Mean 47.2
Standard deviation 5.4
Values 43 51
[18]
HuH.7 POLD2
Mean 64.5
Standard deviation 25
Values 79 36 79
[19]
SNU475 POLD2
Mean 32.5
Standard deviation 4.3
Values 29 35
[20]
THLE POLD2
Mean 47.1
Standard deviation 7.9
Values 41 53
[21]
liver POLD2
Mean 42.1
Standard deviation 24
Values 21 67 57 23
[22]
ref_hepatocyte POLD4
Mean 31.5
Standard deviation 27
Values 1.6 16 64 19 57
[23]
HepG2 POLD4
Mean 15.9
Standard deviation 3.9
Values 19 13
[24]
HepG2.C3A POLD4
Mean 11.1
Standard deviation 4
Values 14 8.3
[25]
HuH.7 POLD4
Mean 45.1
Standard deviation 6.1
Values 39 51 46
[26]
SNU475 POLD4
Mean 157
Standard deviation 53
Values 1.9e+02 1.2e+02
[27]
THLE POLD4
Mean 14.6
Standard deviation 1.8
Values 13 16
[28]
liver POLD4
Mean 32.1
Standard deviation 32
Values 6 48 69 5.3
[29]
ref_hepatocyte RPA2
Mean 23.6
Standard deviation 12
Values 23 41 15 28 11
[30]
HepG2 RPA2
Mean 19
Standard deviation 3.9
Values 16 22
[31]
HepG2.C3A RPA2
Mean 17.8
Standard deviation 8.2
Values 12 24
[32]
HuH.7 RPA2
Mean 25.2
Standard deviation 11
Values 27 14 35
[33]
SNU475 RPA2
Mean 25.9
Standard deviation 7.9
Values 20 31
[34]
THLE RPA2
Mean 30.6
Standard deviation 2.7
Values 29 33
[35]
liver RPA2
Mean 6.36
Standard deviation 3.6
Values 4.2 6.9 11 3.2
[36]
ref_hepatocyte RFC4
Mean 11
Standard deviation 7.9
Values 17 21 4.7 9.8 2.4
[37]
HepG2 RFC4
Mean 12.4
Standard deviation 2.7
Values 10 14
[38]
HepG2.C3A RFC4
Mean 17
Standard deviation 7.7
Values 12 22
[39]
HuH.7 RFC4
Mean 24.4
Standard deviation 12
Values 26 12 35
[40]
SNU475 RFC4
Mean 10.3
Standard deviation 3.5
Values 7.8 13
[41]
THLE RFC4
Mean 29.1
Standard deviation 0.079
Values 29 29
[42]
liver RFC4
Mean 2.31
Standard deviation 1.2
Values 1.9 2.3 4 1
[43]
ref_hepatocyte MSH6
Mean 10.9
Standard deviation 9.5
Values 23 19 4.4 4.3 3.6
[44]
HepG2 MSH6
Mean 30
Standard deviation 7.4
Values 25 35
[45]
HepG2.C3A MSH6
Mean 37.5
Standard deviation 7.9
Values 32 43
[46]
HuH.7 MSH6
Mean 41.5
Standard deviation 12
Values 50 28 47
[47]
SNU475 MSH6
Mean 37.5
Standard deviation 5.6
Values 34 41
[48]
THLE MSH6
Mean 56
Standard deviation 3.5
Values 54 59
[49]
liver MSH6
Mean 19
Standard deviation 6.7
Values 28 11 17 20
[50]
ref_hepatocyte RFC1
Mean 9.26
Standard deviation 5.4
Values 15 15 4.1 7.1 5
[51]
HepG2 RFC1
Mean 22.5
Standard deviation 11
Values 15 30
[52]
HepG2.C3A RFC1
Mean 49.1
Standard deviation 4.6
Values 46 52
[53]
HuH.7 RFC1
Mean 61.4
Standard deviation 8.8
Values 66 67 51
[54]
SNU475 RFC1
Mean 21.2
Standard deviation 2
Values 20 23
[55]
THLE RFC1
Mean 42.7
Standard deviation 3.9
Values 45 40
[56]
liver RFC1
Mean 22.6
Standard deviation 3.4
Values 26 24 18 23
[57]
ref_hepatocyte RFC2
Mean 8.95
Standard deviation 3.2
Values 7.3 13 11 6.2 6.5
[58]
HepG2 RFC2
Mean 16.5
Standard deviation 2.8
Values 14 18
[59]
HepG2.C3A RFC2
Mean 13.3
Standard deviation 5.7
Values 9.3 17
[60]
HuH.7 RFC2
Mean 13.1
Standard deviation 6.2
Values 15 6.1 18
[61]
SNU475 RFC2
Mean 18.6
Standard deviation 4.4
Values 16 22
[62]
THLE RFC2
Mean 28.7
Standard deviation 3.4
Values 26 31
[63]
liver RFC2
Mean 7.44
Standard deviation 4.1
Values 4.9 10 11 3.1
[64]
ref_hepatocyte RPA1
Mean 8.25
Standard deviation 3.9
Values 9.2 15 5.3 5.5 6.7
[65]
HepG2 RPA1
Mean 45.3
Standard deviation 8.3
Values 39 51
[66]
HepG2.C3A RPA1
Mean 33.6
Standard deviation 11
Values 26 41
[67]
HuH.7 RPA1
Mean 39
Standard deviation 14
Values 47 23 48
[68]
SNU475 RPA1
Mean 54.6
Standard deviation 1
Values 55 54
[69]
THLE RPA1
Mean 62.1
Standard deviation 11
Values 54 70
[70]
liver RPA1
Mean 11.7
Standard deviation 1.8
Values 12 12 14 9.5
[71]
ref_hepatocyte RPA3
Mean 8.22
Standard deviation 4.8
Values 6.2 7.6 11 1.9 15
[72]
HepG2 RPA3
Mean 14.1
Standard deviation 4
Values 11 17
[73]
HepG2.C3A RPA3
Mean 21.8
Standard deviation 13
Values 13 31
[74]
HuH.7 RPA3
Mean 34.5
Standard deviation 16
Values 35 18 50
[75]
SNU475 RPA3
Mean 8.05
Standard deviation 1.5
Values 9.1 7
[76]
THLE RPA3
Mean 11
Standard deviation 2.9
Values 8.9 13
[77]
liver RPA3
Mean 7.22
Standard deviation 6.1
Values 2.4 13 12 1.4
[78]
ref_hepatocyte MLH1
Mean 6.5
Standard deviation 1.5
Values 4.7 6.4 8.4 5.5 7.5
[79]
HepG2 MLH1
Mean 25.9
Standard deviation 4.9
Values 22 29
[80]
HepG2.C3A MLH1
Mean 25.1
Standard deviation 3.7
Values 22 28
[81]
HuH.7 MLH1
Mean 40.4
Standard deviation 11
Values 44 28 50
[82]
SNU475 MLH1
Mean 13.2
Standard deviation 0.12
Values 13 13
[83]
THLE MLH1
Mean 23.2
Standard deviation 4.4
Values 20 26
[84]
liver MLH1
Mean 12.4
Standard deviation 3.5
Values 13 11 17 9.1
[85]
ref_hepatocyte RFC5
Mean 5.54
Standard deviation 4.9
Values 13 7.4 3.6 0.42 3.2
[86]
HepG2 RFC5
Mean 13.4
Standard deviation 5.4
Values 9.6 17
[87]
HepG2.C3A RFC5
Mean 16.4
Standard deviation 10
Values 9 24
[88]
HuH.7 RFC5
Mean 18.1
Standard deviation 6.8
Values 23 10 21
[89]
SNU475 RFC5
Mean 12.2
Standard deviation 2.4
Values 11 14
[90]
THLE RFC5
Mean 19.8
Standard deviation 2.4
Values 18 22
[91]
liver RFC5
Mean 4.29
Standard deviation 1.7
Values 3.5 4.9 6.3 2.5
[92]
ref_hepatocyte PMS2
Mean 5.16
Standard deviation 1.2
Values 3.8 6.9 4.7 4.6 5.7
[93]
HepG2 PMS2
Mean 4.28
Standard deviation 0.47
Values 3.9 4.6
[94]
HepG2.C3A PMS2
Mean 3.16
Standard deviation 0.96
Values 2.5 3.8
[95]
HuH.7 PMS2
Mean 5.68
Standard deviation 1.5
Values 7.4 4.7 4.9
[96]
SNU475 PMS2
Mean 6.27
Standard deviation 0.36
Values 6.5 6
[97]
THLE PMS2
Mean 5.67
Standard deviation 0.91
Values 5 6.3
[98]
liver PMS2
Mean 2.75
Standard deviation 0.94
Values 4.1 1.8 2.6 2.5
[99]
ref_hepatocyte MSH2
Mean 3.98
Standard deviation 3.2
Values 8.5 6.1 1.3 2.4 1.5
[100]
HepG2 MSH2
Mean 15.5
Standard deviation 8
Values 9.9 21
[101]
HepG2.C3A MSH2
Mean 33.8
Standard deviation 15
Values 23 45
[102]
HuH.7 MSH2
Mean 22.1
Standard deviation 10
Values 28 10 28
[103]
SNU475 MSH2
Mean 32
Standard deviation 6.8
Values 27 37
[104]
THLE MSH2
Mean 23.1
Standard deviation 1.9
Values 22 24
[105]
liver MSH2
Mean 3.5
Standard deviation 1.1
Values 4.8 2.3 4 2.9
[106]
ref_hepatocyte RFC3
Mean 3.17
Standard deviation 3.1
Values 6.3 6.7 0.35 1.4 1.1
[107]
HepG2 RFC3
Mean 15.8
Standard deviation 7.8
Values 10 21
[108]
HepG2.C3A RFC3
Mean 25.6
Standard deviation 17
Values 14 37
[109]
HuH.7 RFC3
Mean 27.1
Standard deviation 12
Values 35 14 33
[110]
SNU475 RFC3
Mean 13.8
Standard deviation 3.5
Values 11 16
[111]
THLE RFC3
Mean 23.5
Standard deviation 5.4
Values 20 27
[112]
liver RFC3
Mean 2.46
Standard deviation 0.85
Values 2.9 2 3.4 1.5
[113]
ref_hepatocyte LIG1
Mean 3.08
Standard deviation 2.7
Values 7.4 3.8 2.1 0.82 1.3
[114]
HepG2 LIG1
Mean 21.1
Standard deviation 4.6
Values 18 24
[115]
HepG2.C3A LIG1
Mean 19
Standard deviation 5
Values 15 23
[116]
HuH.7 LIG1
Mean 28.4
Standard deviation 13
Values 35 13 37
[117]
SNU475 LIG1
Mean 8.05
Standard deviation 0.33
Values 8.3 7.8
[118]
THLE LIG1
Mean 15.1
Standard deviation 4
Values 12 18
[119]
liver LIG1
Mean 3.39
Standard deviation 0.66
Values 3.3 3.3 4.3 2.7
[120]
ref_hepatocyte POLD1
Mean 2.41
Standard deviation 0.8
Values 2 3.5 2.4 2.7 1.4
[121]
HepG2 POLD1
Mean 19.3
Standard deviation 1.9
Values 21 18
[122]
HepG2.C3A POLD1
Mean 20.1
Standard deviation 2.3
Values 18 22
[123]
HuH.7 POLD1
Mean 34
Standard deviation 15
Values 42 16 44
[124]
SNU475 POLD1
Mean 15.6
Standard deviation 2.9
Values 14 18
[125]
THLE POLD1
Mean 29.7
Standard deviation 2.6
Values 28 32
[126]
liver POLD1
Mean 5.43
Standard deviation 0.68
Values 4.7 6.2 5.8 5.1
[127]
ref_hepatocyte MSH3
Mean 1.7
Standard deviation 0.72
Values 2.9 1.5 1.7 1 1.3
[128]
HepG2 MSH3
Mean 6.3
Standard deviation 2.4
Values 4.6 8
[129]
HepG2.C3A MSH3
Mean 8.59
Standard deviation 2.2
Values 7 10
[130]
HuH.7 MSH3
Mean 7.11
Standard deviation 0.77
Values 7.9 7.1 6.3
[131]
SNU475 MSH3
Mean 8.69
Standard deviation 0.99
Values 8 9.4
[132]
THLE MSH3
Mean 9.02
Standard deviation 0.64
Values 8.6 9.5
[133]
liver MSH3
Mean 12.9
Standard deviation 2.9
Values 13 14 9 16
[134]
ref_hepatocyte POLD3
Mean 1.46
Standard deviation 0.56
Values 1.9 1.9 1.8 1 0.71
[135]
HepG2 POLD3
Mean 7.29
Standard deviation 0.95
Values 6.6 8
[136]
HepG2.C3A POLD3
Mean 5.94
Standard deviation 4
Values 3.1 8.8
[137]
HuH.7 POLD3
Mean 11.2
Standard deviation 6.1
Values 15 4.1 14
[138]
SNU475 POLD3
Mean 11.6
Standard deviation 3.7
Values 9 14
[139]
THLE POLD3
Mean 18.3
Standard deviation 1.6
Values 17 19
[140]
liver POLD3
Mean 4.11
Standard deviation 1.1
Values 4.3 3.6 5.6 3
[141]
ref_hepatocyte MLH3
Mean 1.08
Standard deviation 0.29
Values 0.75 1.4 1 1.3 0.88
[142]
HepG2 MLH3
Mean 5.81
Standard deviation 0.46
Values 5.5 6.1
[143]
HepG2.C3A MLH3
Mean 12
Standard deviation 0.89
Values 11 13
[144]
HuH.7 MLH3
Mean 6.59
Standard deviation 0.95
Values 7.3 5.5 7
[145]
SNU475 MLH3
Mean 9.4
Standard deviation 0.16
Values 9.3 9.5
[146]
THLE MLH3
Mean 8.2
Standard deviation 0.98
Values 8.9 7.5
[147]
liver MLH3
Mean 16.2
Standard deviation 6
Values 20 11 11 23
[148]
ref_hepatocyte EXO1
Mean 0.669
Standard deviation 0.56
Values 1.1 1.4 0.53 0.19 0.12
[149]
HepG2 EXO1
Mean 5.53
Standard deviation 3.6
Values 3 8
[150]
HepG2.C3A EXO1
Mean 6
Standard deviation 4.2
Values 3.1 8.9
[151]
HuH.7 EXO1
Mean 13
Standard deviation 8
Values 18 3.7 17
[152]
SNU475 EXO1
Mean 16.8
Standard deviation 6.9
Values 12 22
[153]
THLE EXO1
Mean 11.5
Standard deviation 1.2
Values 11 12
[154]
liver EXO1
Mean 0.343
Standard deviation 0.28
Values 0.73 0.28 0.31 0.053
[155]
ref_hepatocyte RPA4
Mean 0.168
Standard deviation 0.15
Values 0 0.15 0.18 0.41 0.098
[156]
HepG2 RPA4
Mean 0.01
Standard deviation 0.002
Values 0.011 0.0086
[157]
HepG2.C3A RPA4
Mean 0.0107
Standard deviation 0.015
Values 0 0.021
[158]
HuH.7 RPA4
Mean 0
Standard deviation 0
Values 0 0 0
[159]
SNU475 RPA4
Mean 0.0927
Standard deviation 0.098
Values 0.023 0.16
[160]
THLE RPA4
Mean 0.103
Standard deviation 0.0041
Values 0.1 0.11
[161]
liver RPA4
Mean 0.857
Standard deviation 0.15
Values 1 0.94 0.67 0.81