KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION |
Return to index |
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Order |
Gene |
Description |
ref_hepatocyte |
HepG2 |
HepG2.C3A |
HuH.7 |
SNU475 |
THLE |
liver |
1 |
ACTB |
Actin, cytoplasmic 1 |
[1] |
-0.90[2] |
-1.17[3] |
-0.77[4] |
-0.73[5] |
-0.92[6] |
-0.40[7] |
2 |
ACTG1 |
Actin, cytoplasmic 2 |
[8] |
0.38[9] |
-0.53[10] |
-0.66[11] |
-0.92[12] |
-0.34[13] |
-1.15[14] |
3 |
MYL12B |
Myosin regulatory light chain 12B |
[15] |
-1.52[16] |
-0.99[17] |
-1.25[18] |
-1.24[19] |
-1.77[20] |
-1.61[21] |
4 |
MYL12A |
Myosin regulatory light chain 12A |
[22] |
-1.29[23] |
-0.85[24] |
-0.88[25] |
-1.22[26] |
-1.65[27] |
-1.04[28] |
5 |
RHOA |
Transforming protein RhoA |
[29] |
-0.45[30] |
-0.54[31] |
-0.54[32] |
-0.96[33] |
-0.32[34] |
-0.54[35] |
6 |
ITGB1 |
Integrin beta-1 |
[36] |
0.72[37] |
1.16[38] |
1.06[39] |
1.73[40] |
1.99[41] |
0.95[42] |
7 |
CDC42 |
Cell division control protein 42 homolog |
[43] |
-0.34[44] |
0.79[45] |
-0.44[46] |
-0.27[47] |
-0.80[48] |
-1.30[49] |
8 |
RAP1B |
Ras-related protein Rap-1b |
[50] |
-1.81[51] |
-0.79[52] |
-1.24[53] |
-0.26[54] |
-0.32[55] |
-1.10[56] |
9 |
MSN |
Moesin |
[57] |
-7.60[58] |
-9.49[59] |
-8.41[60] |
1.27[61] |
0.46[62] |
-0.49[63] |
10 |
CD99 |
CD99 antigen |
[64] |
[65] |
[66] |
[67] |
[68] |
[69] |
[70] |
11 |
CLDN1 |
Claudin-1 |
[71] |
-0.76[72] |
0.16[73] |
1.67[74] |
-5.24[75] |
-2.33[76] |
0.68[77] |
12 |
ACTN4 |
Alpha-actinin-4 |
[78] |
1.31[79] |
1.26[80] |
1.18[81] |
1.55[82] |
0.88[83] |
0.42[84] |
13 |
RAC1 |
Ras-related C3 botulinum toxin substrate 1 |
[85] |
0.10[86] |
0.18[87] |
0.66[88] |
0.28[89] |
0.45[90] |
-0.18[91] |
14 |
ACTN1 |
Alpha-actinin-1 |
[92] |
1.31[93] |
0.84[94] |
-0.05[95] |
1.98[96] |
1.52[97] |
0.82[98] |
15 |
CTNNB1 |
Catenin beta-1 |
[99] |
2.11[100] |
2.01[101] |
2.68[102] |
1.02[103] |
1.44[104] |
1.89[105] |
16 |
CTNNA1 |
Catenin alpha-1 |
[106] |
1.94[107] |
1.84[108] |
1.16[109] |
1.62[110] |
1.44[111] |
1.41[112] |
17 |
GNAI2 |
Guanine nucleotide-binding protein G(i) subunit alpha-2 |
[113] |
0.56[114] |
-0.09[115] |
-0.16[116] |
0.10[117] |
1.35[118] |
0.59[119] |
18 |
VASP |
Vasodilator-stimulated phosphoprotein |
[120] |
0.35[121] |
0.37[122] |
0.50[123] |
0.04[124] |
-0.65[125] |
-2.14[126] |
19 |
EZR |
Ezrin |
[127] |
1.46[128] |
0.50[129] |
1.04[130] |
-0.07[131] |
1.35[132] |
0.40[133] |
20 |
F11R |
Junctional adhesion molecule A |
[134] |
1.05[135] |
1.82[136] |
0.92[137] |
-2.19[138] |
-0.87[139] |
1.41[140] |
21 |
PTPN11 |
Tyrosine-protein phosphatase non-receptor type 11 |
[141] |
0.94[142] |
1.78[143] |
1.51[144] |
1.16[145] |
1.98[146] |
2.04[147] |
22 |
CTNND1 |
Catenin delta-1 |
[148] |
-3.28[149] |
-3.39[150] |
-3.04[151] |
-3.83[152] |
-4.00[153] |
-2.96[154] |
23 |
RAP1A |
Ras-related protein Rap-1A |
[155] |
-0.56[156] |
-0.21[157] |
0.40[158] |
0.05[159] |
0.00[160] |
-0.50[161] |
24 |
GNAI3 |
Guanine nucleotide-binding protein G(k) subunit alpha |
[162] |
0.62[163] |
1.57[164] |
1.44[165] |
1.37[166] |
1.19[167] |
1.02[168] |
25 |
CYBA |
Cytochrome b-245 light chain |
[169] |
1.98[170] |
2.43[171] |
1.10[172] |
0.48[173] |
0.56[174] |
-0.63[175] |
26 |
ICAM1 |
Intercellular adhesion molecule 1 |
[176] |
2.39[177] |
2.17[178] |
2.36[179] |
0.46[180] |
2.82[181] |
0.37[182] |
27 |
CLDN3 |
Claudin-3 |
[183] |
-5.02[184] |
-1.33[185] |
-2.98[186] |
-4.27[187] |
-9.29[188] |
-0.26[189] |
28 |
VCL |
Vinculin |
[190] |
1.26[191] |
1.39[192] |
1.30[193] |
3.10[194] |
2.38[195] |
1.59[196] |
29 |
NCF2 |
Neutrophil cytosol factor 2 |
[197] |
-1.32[198] |
-3.61[199] |
-7.60[200] |
-2.62[201] |
-9.05[202] |
-1.63[203] |
30 |
CLDN6 |
Claudin-6 |
[204] |
1.77[205] |
1.57[206] |
-2.71[207] |
-7.93[208] |
-8.17[209] |
-7.91[210] |
31 |
BCAR1 |
Breast cancer anti-estrogen resistance protein 1 |
[211] |
1.62[212] |
1.91[213] |
0.56[214] |
1.64[215] |
1.55[216] |
0.85[217] |
32 |
PXN |
Paxillin |
[218] |
1.49[219] |
1.62[220] |
1.43[221] |
2.38[222] |
2.53[223] |
0.43[224] |
33 |
PTK2 |
Focal adhesion kinase 1 |
[225] |
1.23[226] |
2.12[227] |
2.28[228] |
2.21[229] |
1.60[230] |
1.55[231] |
34 |
MAPK14 |
Mitogen-activated protein kinase 14 |
[232] |
1.96[233] |
2.44[234] |
1.79[235] |
1.95[236] |
1.61[237] |
2.07[238] |
35 |
VAV2 |
Guanine nucleotide exchange factor VAV2 |
[239] |
1.79[240] |
2.45[241] |
1.72[242] |
-0.27[243] |
0.34[244] |
1.30[245] |
36 |
CLDN4 |
Claudin-4 |
[246] |
2.12[247] |
1.64[248] |
-3.06[249] |
-0.01[250] |
-6.37[251] |
-2.99[252] |
37 |
CLDN14 |
Claudin-14 |
[253] |
-5.39[254] |
-1.61[255] |
-1.83[256] |
-8.39[257] |
-6.81[258] |
0.06[259] |
38 |
PIK3R1 |
Phosphatidylinositol 3-kinase regulatory subunit alpha |
[260] |
0.02[261] |
0.55[262] |
1.41[263] |
2.33[264] |
2.02[265] |
3.79[266] |
39 |
ROCK1 |
Rho-associated protein kinase 1 |
[267] |
-0.46[268] |
1.47[269] |
2.02[270] |
1.63[271] |
1.16[272] |
2.37[273] |
40 |
GNAI1 |
Guanine nucleotide-binding protein G(i) subunit alpha-1 |
[274] |
-1.16[275] |
-1.69[276] |
0.23[277] |
1.48[278] |
1.04[279] |
1.62[280] |
41 |
OCLN |
Occludin |
[281] |
0.24[282] |
1.61[283] |
1.63[284] |
-1.86[285] |
-3.25[286] |
2.48[287] |
42 |
MAPK13 |
Mitogen-activated protein kinase 13 |
[288] |
2.83[289] |
3.65[290] |
0.74[291] |
-1.62[292] |
0.09[293] |
-0.93[294] |
43 |
PIK3R2 |
Phosphatidylinositol 3-kinase regulatory subunit beta |
[295] |
2.36[296] |
3.00[297] |
3.38[298] |
0.97[299] |
1.72[300] |
0.50[301] |
44 |
ROCK2 |
Rho-associated protein kinase 2 |
[302] |
1.97[303] |
3.62[304] |
1.86[305] |
2.90[306] |
0.86[307] |
2.71[308] |
45 |
MYL9 |
Myosin regulatory light polypeptide 9 |
[309] |
1.55[310] |
1.77[311] |
-1.15[312] |
4.85[313] |
2.49[314] |
0.71[315] |
46 |
CLDN2 |
Claudin-2 |
[316] |
-2.53[317] |
-1.10[318] |
-0.11[319] |
-2.74[320] |
-6.86[321] |
2.37[322] |
47 |
MYL5 |
Myosin light chain 5 |
[323] |
-3.93[324] |
-1.35[325] |
-2.02[326] |
-2.88[327] |
-4.15[328] |
-2.33[329] |
48 |
ARHGAP35 |
Rho GTPase-activating protein 35 |
[330] |
2.83[331] |
3.38[332] |
3.69[333] |
3.00[334] |
2.77[335] |
4.05[336] |
49 |
ARHGAP5 |
Rho GTPase-activating protein 5 |
[337] |
2.90[338] |
2.92[339] |
5.99[340] |
2.84[341] |
2.61[342] |
3.93[343] |
50 |
RAC2 |
Ras-related C3 botulinum toxin substrate 2 |
[344] |
-1.22[345] |
-6.80[346] |
-7.63[347] |
-1.12[348] |
2.87[349] |
-0.45[350] |
51 |
CLDN7 |
Claudin-7 |
[351] |
-7.72[352] |
-5.60[353] |
-1.05[354] |
-0.05[355] |
-5.64[356] |
0.41[357] |
52 |
PLCG1 |
1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase gamma-1 |
3.98[358] |
4.01[359] |
3.12[360] |
3.09[361] |
2.77[362] |
1.13[363] |
53 |
ITGB2 |
Integrin beta-2 |
[364] |
1.78[365] |
3.58[366] |
-4.93[367] |
-4.92[368] |
-6.72[369] |
2.10[370] |
54 |
PIK3CB |
Phosphatidylinositol
4,5-bisphosphate 3-kinase catalytic subunit beta isoform |
1.70[371] |
2.62[372] |
2.55[373] |
1.32[374] |
1.66[375] |
1.94[376] |
55 |
CLDN23 |
Claudin-23 |
[377] |
-4.25[378] |
-3.39[379] |
-0.07[380] |
-1.83[381] |
-2.14[382] |
0.83[383] |
56 |
SIPA1 |
Signal-induced proliferation-associated protein 1 |
[384] |
1.68[385] |
0.77[386] |
1.34[387] |
1.72[388] |
2.37[389] |
2.07[390] |
57 |
PRKCA |
Protein kinase C alpha type |
[391] |
3.33[392] |
3.78[393] |
3.91[394] |
2.42[395] |
2.96[396] |
2.70[397] |
58 |
CXCR4 |
C-X-C chemokine receptor type 4 |
[398] |
-1.37[399] |
[400] |
-1.65[401] |
-5.29[402] |
-1.27[403] |
0.72[404] |
59 |
CLDN15 |
Claudin-15 |
[405] |
0.01[406] |
0.95[407] |
0.74[408] |
-0.60[409] |
0.05[410] |
0.20[411] |
60 |
PIK3CA |
Phosphatidylinositol
4,5-bisphosphate 3-kinase catalytic subunit alpha isoform |
0.11[412] |
2.16[413] |
2.12[414] |
1.40[415] |
1.79[416] |
2.70[417] |
61 |
PIK3CD |
Phosphatidylinositol
4,5-bisphosphate 3-kinase catalytic subunit delta isoform |
2.38[418] |
3.87[419] |
-0.16[420] |
0.55[421] |
1.50[422] |
1.08[423] |
62 |
PTK2B |
Protein-tyrosine kinase 2-beta |
[424] |
-0.32[425] |
1.45[426] |
2.19[427] |
-1.51[428] |
1.30[429] |
2.56[430] |
63 |
RASSF5 |
Ras association domain-containing protein 5 |
[431] |
1.21[432] |
-3.04[433] |
1.37[434] |
1.62[435] |
0.93[436] |
2.06[437] |
64 |
NCF1 |
Neutrophil cytosol factor 1 |
[438] |
-6.67[439] |
-8.32[440] |
[441] |
[442] |
-8.84[443] |
-2.01[444] |
65 |
CYBB |
Cytochrome b-245 heavy chain |
[445] |
[446] |
[447] |
-9.54[448] |
-4.21[449] |
-9.57[450] |
3.84[451] |
66 |
VCAM1 |
Vascular cell adhesion protein 1 |
[452] |
-6.53[453] |
[454] |
-3.11[455] |
0.79[456] |
4.37[457] |
4.32[458] |
67 |
RAPGEF4 |
Rap guanine nucleotide exchange factor 4 |
[459] |
-3.53[460] |
-1.32[461] |
-0.63[462] |
-1.40[463] |
1.19[464] |
3.68[465] |
68 |
PLCG2 |
1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase gamma-2 |
-0.79[466] |
-6.13[467] |
1.09[468] |
-2.47[469] |
-1.13[470] |
3.50[471] |
69 |
ITGAL |
Integrin alpha-L |
[472] |
-0.13[473] |
2.13[474] |
3.59[475] |
-4.03[476] |
-3.74[477] |
2.93[478] |
70 |
CXCL12 |
Stromal cell-derived factor 1 |
[479] |
-6.09[480] |
-5.13[481] |
-4.81[482] |
3.75[483] |
5.63[484] |
5.31[485] |
71 |
MMP9 |
Matrix metalloproteinase-9 |
[486] |
-2.23[487] |
-2.87[488] |
-5.49[489] |
-1.16[490] |
-3.54[491] |
0.65[492] |
72 |
MAPK12 |
Mitogen-activated protein kinase 12 |
[493] |
3.31[494] |
3.38[495] |
4.27[496] |
1.75[497] |
3.19[498] |
-0.12[499] |
73 |
CLDN5 |
Claudin-5 |
[500] |
-3.18[501] |
-2.32[502] |
-4.52[503] |
-6.53[504] |
-3.67[505] |
3.59[506] |
74 |
CLDN11 |
Claudin-11 |
[507] |
1.58[508] |
3.18[509] |
-2.32[510] |
4.68[511] |
2.42[512] |
7.99[513] |
75 |
NCF4 |
Neutrophil cytosol factor 4 |
[514] |
-5.27[515] |
-7.18[516] |
[517] |
-7.79[518] |
[519] |
1.70[520] |
76 |
PECAM1 |
Platelet endothelial cell adhesion molecule |
[521] |
-1.87[522] |
-1.71[523] |
2.64[524] |
-2.24[525] |
-2.50[526] |
3.51[527] |
77 |
THY1 |
Thy-1 membrane glycoprotein |
[528] |
-5.86[529] |
-5.91[530] |
-4.97[531] |
2.83[532] |
6.29[533] |
1.34[534] |
78 |
ESAM |
Endothelial cell-selective adhesion molecule |
[535] |
4.85[536] |
3.14[537] |
-3.46[538] |
1.76[539] |
-2.83[540] |
3.78[541] |
79 |
VAV3 |
Guanine nucleotide exchange factor VAV3 |
[542] |
2.30[543] |
1.00[544] |
2.95[545] |
3.95[546] |
-1.84[547] |
2.14[548] |
80 |
CDH5 |
Cadherin-5 |
[549] |
-1.09[550] |
-2.83[551] |
[552] |
-4.64[553] |
-5.01[554] |
5.32[555] |
81 |
VAV1 |
Proto-oncogene vav |
[556] |
-8.01[557] |
-2.77[558] |
-4.70[559] |
-5.82[560] |
-6.90[561] |
1.97[562] |
82 |
PIK3R3 |
Phosphatidylinositol 3-kinase regulatory subunit gamma |
[563] |
2.21[564] |
2.63[565] |
3.25[566] |
3.43[567] |
2.64[568] |
3.46[569] |
83 |
ITGAM |
Integrin alpha-M |
[570] |
-1.91[571] |
-4.05[572] |
-3.05[573] |
-2.32[574] |
-4.56[575] |
3.70[576] |
84 |
MAPK11 |
Mitogen-activated protein kinase 11 |
[577] |
0.32[578] |
0.63[579] |
-0.49[580] |
0.62[581] |
2.80[582] |
0.95[583] |
85 |
PIK3R5 |
Phosphoinositide 3-kinase regulatory subunit 5 |
[584] |
-6.68[585] |
[586] |
-1.86[587] |
-3.66[588] |
-3.13[589] |
3.12[590] |
86 |
CLDN19 |
Claudin-19 |
[591] |
3.64[592] |
3.86[593] |
0.69[594] |
-2.83[595] |
-3.25[596] |
-1.65[597] |
87 |
CLDN16 |
Claudin-16 |
[598] |
-1.05[599] |
0.41[600] |
4.12[601] |
-3.13[602] |
-2.58[603] |
0.76[604] |
88 |
PRKCB |
Protein kinase C beta type |
[605] |
-6.32[606] |
-4.72[607] |
[608] |
2.75[609] |
-2.37[610] |
4.32[611] |
89 |
JAM2 |
Junctional adhesion molecule B |
[612] |
-2.31[613] |
0.56[614] |
-0.87[615] |
-0.38[616] |
0.38[617] |
3.26[618] |
90 |
ITGA4 |
Integrin alpha-4 |
[619] |
-3.16[620] |
[621] |
-0.49[622] |
7.86[623] |
4.69[624] |
4.22[625] |
91 |
CLDN18 |
Claudin-18 |
[626] |
-6.21[627] |
-3.41[628] |
-1.05[629] |
-0.31[630] |
-0.93[631] |
0.36[632] |
92 |
MMP2 |
72 kDa type IV collagenase |
[633] |
3.93[634] |
-2.65[635] |
-1.60[636] |
7.70[637] |
7.44[638] |
4.72[639] |
93 |
ITK |
Tyrosine-protein kinase ITK/TSK |
[640] |
-6.41[641] |
-3.02[642] |
[643] |
0.10[644] |
-4.45[645] |
2.98[646] |
94 |
RHOH |
Rho-related GTP-binding protein RhoH |
[647] |
-2.59[648] |
-2.98[649] |
2.74[650] |
-3.52[651] |
-3.14[652] |
2.32[653] |
95 |
JAM3 |
Junctional adhesion molecule C |
[654] |
5.14[655] |
1.79[656] |
1.38[657] |
5.70[658] |
6.98[659] |
5.02[660] |
96 |
CLDN9 |
Claudin-9 |
[661] |
3.33[662] |
2.71[663] |
0.42[664] |
-2.48[665] |
-1.32[666] |
1.68[667] |
97 |
CTNNA3 |
Catenin alpha-3 |
[668] |
-4.73[669] |
[670] |
[671] |
-5.00[672] |
-4.19[673] |
3.82[674] |
98 |
MYL10 |
Myosin regulatory light chain 10 |
[675] |
-0.65[676] |
-1.30[677] |
-1.69[678] |
-2.06[679] |
-2.68[680] |
-1.22[681] |
99 |
RAPGEF3 |
Rap guanine nucleotide exchange factor 3 |
[682] |
2.31[683] |
2.40[684] |
1.61[685] |
2.15[686] |
0.99[687] |
4.60[688] |
100 |
PIK3CG |
Phosphatidylinositol
4,5-bisphosphate 3-kinase catalytic subunit gamma isoform |
[689] |
[690] |
[691] |
1.61[692] |
-3.09[693] |
4.88[694] |
101 |
CLDN10 |
Claudin-10 |
[695] |
-1.28[696] |
[697] |
-4.57[698] |
-0.90[699] |
-0.66[700] |
5.64[701] |
102 |
TXK |
Tyrosine-protein kinase TXK |
[702] |
[703] |
-1.74[704] |
-4.72[705] |
1.94[706] |
0.44[707] |
4.89[708] |
103 |
PRKCG |
Protein kinase C gamma type |
[709] |
-0.33[710] |
0.75[711] |
-1.85[712] |
-0.80[713] |
-0.70[714] |
[715] |
104 |
NOX1 |
NADPH oxidase 1 |
[716] |
0.85[717] |
0.49[718] |
5.43[719] |
0.20[720] |
1.77[721] |
1.62[722] |
105 |
ACTN2 |
Alpha-actinin-2 |
[723] |
0.76[724] |
1.38[725] |
-1.15[726] |
2.50[727] |
2.40[728] |
3.70[729] |
106 |
CTNNA2 |
Catenin alpha-2 |
[730] |
1.29[731] |
-1.25[732] |
-2.60[733] |
[734] |
-2.48[735] |
0.55[736] |
107 |
ACTN3 |
Alpha-actinin-3 |
[737] |
3.67[738] |
4.02[739] |
5.01[740] |
-2.09[741] |
-0.92[742] |
[743] |
108 |
CLDN20 |
Claudin-20 |
[744] |
[745] |
[746] |
[747] |
[748] |
[749] |
[750] |
109 |
MYL2 |
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform |
[751] |
[752] |
[753] |
[754] |
[755] |
[756] |
[757] |
110 |
MYL7 |
Myosin regulatory light chain 2, atrial isoform |
[758] |
[759] |
[760] |
[761] |
[762] |
[763] |
[764] |
111 |
MYLPF |
Myosin regulatory light chain 2, skeletal muscle isoform |
[765] |
[766] |
[767] |
[768] |
[769] |
[770] |
[771] |
112 |
CLDN8 |
Claudin-8 |
[772] |
[773] |
[774] |
[775] |
[776] |
[777] |
[778] |
113 |
CLDN22 |
Claudin-22 |
[779] |
[780] |
[781] |
[782] |
[783] |
[784] |
[785] |
114 |
CLDN17 |
Claudin-17 |
[786] |
[787] |
[788] |
[789] |
[790] |
[791] |
[792] |
115 |
NOX3 |
NADPH oxidase 3 |
[793] |
[794] |
[795] |
[796] |
[797] |
[798] |
[799] |
116 |
AFDN |
Afadin |
[800] |
[801] |
[802] |
[803] |
[804] |
[805] |
[806] |
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