KEGG_LEISHMANIA_INFECTION |
Return to index |
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Order |
Gene |
Description |
ref_hepatocyte |
HepG2 |
HepG2.C3A |
HuH.7 |
SNU475 |
THLE |
liver |
1 |
C3 |
Complement C3 |
[1] |
-0.63[2] |
-0.21[3] |
-1.58[4] |
-6.11[5] |
-2.25[6] |
0.31[7] |
2 |
ITGB1 |
Integrin beta-1 |
[8] |
0.98[9] |
0.76[10] |
2.04[11] |
2.74[12] |
2.68[13] |
-0.88[14] |
3 |
NFKBIA |
NF-kappa-B inhibitor alpha |
[15] |
-0.31[16] |
-2.35[17] |
-1.57[18] |
-2.24[19] |
-0.50[20] |
-2.18[21] |
4 |
JUN |
Transcription factor AP-1 |
[22] |
0.26[23] |
-1.53[24] |
-0.11[25] |
-0.42[26] |
0.00[27] |
-2.85[28] |
5 |
FOS |
Proto-oncogene c-Fos |
[29] |
-5.26[30] |
-4.25[31] |
-3.76[32] |
-4.89[33] |
-3.96[34] |
-2.35[35] |
6 |
HLA-DRA |
HLA class II histocompatibility antigen, DR alpha chain |
[36] |
-12.52[37] |
[38] |
-12.62[39] |
-4.47[40] |
-6.54[41] |
-1.61[42] |
7 |
IFNGR1 |
Interferon gamma receptor 1 |
[43] |
1.53[44] |
0.16[45] |
-0.14[46] |
0.90[47] |
0.51[48] |
-1.36[49] |
8 |
MARCKSL1 |
MARCKS-related protein |
[50] |
2.25[51] |
1.45[52] |
3.23[53] |
0.84[54] |
0.92[55] |
-2.77[56] |
9 |
IRAK1 |
Interleukin-1 receptor-associated kinase 1 |
[57] |
2.16[58] |
1.31[59] |
1.44[60] |
2.07[61] |
2.30[62] |
-1.73[63] |
10 |
STAT1 |
Signal transducer and activator of transcription 1-alpha/beta |
[64] |
0.67[65] |
-0.49[66] |
1.77[67] |
3.81[68] |
1.40[69] |
-0.09[70] |
11 |
HLA-DRB1 |
HLA class II histocompatibility antigen, DRB1-15 beta chain |
[71] |
-7.69[72] |
[73] |
[74] |
-4.83[75] |
-10.04[76] |
-2.70[77] |
12 |
RELA |
Transcription factor p65 |
[78] |
0.88[79] |
0.13[80] |
1.42[81] |
1.22[82] |
0.99[83] |
-1.92[84] |
13 |
IFNGR2 |
Interferon gamma receptor 2 |
[85] |
0.71[86] |
1.02[87] |
0.16[88] |
-0.09[89] |
1.06[90] |
-1.63[91] |
14 |
JAK1 |
Tyrosine-protein kinase JAK1 |
[92] |
1.26[93] |
0.50[94] |
1.84[95] |
1.91[96] |
2.41[97] |
0.49[98] |
15 |
CYBA |
Cytochrome b-245 light chain |
[99] |
2.24[100] |
2.03[101] |
2.08[102] |
1.49[103] |
1.24[104] |
-2.46[105] |
16 |
NFKBIB |
NF-kappa-B inhibitor beta |
[106] |
-0.41[107] |
-0.84[108] |
0.65[109] |
-0.54[110] |
-0.33[111] |
-2.77[112] |
17 |
MYD88 |
Myeloid differentiation primary response protein MyD88 |
[113] |
0.56[114] |
0.37[115] |
0.96[116] |
0.24[117] |
0.40[118] |
-0.25[119] |
18 |
NCF2 |
Neutrophil cytosol factor 2 |
[120] |
-1.06[121] |
-4.01[122] |
-6.62[123] |
-1.60[124] |
-8.37[125] |
-3.46[126] |
19 |
MAPK1 |
Mitogen-activated protein kinase 1 |
[127] |
2.46[128] |
2.35[129] |
3.33[130] |
3.13[131] |
2.63[132] |
0.73[133] |
20 |
TAB2 |
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 |
[134] |
1.11[135] |
1.03[136] |
2.45[137] |
2.98[138] |
2.29[139] |
-0.80[140] |
21 |
MAPK14 |
Mitogen-activated protein kinase 14 |
[141] |
2.22[142] |
2.04[143] |
2.77[144] |
2.96[145] |
2.29[146] |
0.24[147] |
22 |
MAP3K7 |
Mitogen-activated protein kinase kinase kinase 7 |
[148] |
0.65[149] |
1.47[150] |
2.50[151] |
1.77[152] |
1.81[153] |
-0.79[154] |
23 |
HLA-DPA1 |
HLA class II histocompatibility antigen, DP alpha 1 chain |
[155] |
-6.19[156] |
-9.94[157] |
[158] |
-3.82[159] |
-5.81[160] |
-1.33[161] |
24 |
HLA-DRB5 |
HLA class II histocompatibility antigen, DR beta 5 chain |
[162] |
-10.34[163] |
[164] |
[165] |
-7.08[166] |
[167] |
-6.89[168] |
25 |
ELK1 |
ETS domain-containing protein Elk-1 |
[169] |
0.43[170] |
-1.95[171] |
1.62[172] |
1.55[173] |
2.00[174] |
-1.21[175] |
26 |
NFKB1 |
Nuclear factor NF-kappa-B p105 subunit |
[176] |
1.42[177] |
0.85[178] |
1.79[179] |
1.03[180] |
1.80[181] |
-0.59[182] |
27 |
FCGR3A |
Low affinity immunoglobulin gamma Fc region receptor III-A |
[183] |
[184] |
[185] |
[186] |
-8.71[187] |
[188] |
-0.16[189] |
28 |
MAPK13 |
Mitogen-activated protein kinase 13 |
[190] |
3.09[191] |
3.24[192] |
1.72[193] |
-0.61[194] |
0.77[195] |
-2.76[196] |
29 |
PTPN6 |
Tyrosine-protein phosphatase non-receptor type 6 |
[197] |
0.28[198] |
0.23[199] |
1.96[200] |
-5.86[201] |
-0.98[202] |
-1.22[203] |
30 |
MAPK3 |
Mitogen-activated protein kinase 3 |
[204] |
2.60[205] |
2.40[206] |
3.59[207] |
1.70[208] |
1.58[209] |
-2.08[210] |
31 |
TAB1 |
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 |
[211] |
1.39[212] |
1.79[213] |
3.03[214] |
1.29[215] |
1.48[216] |
-0.82[217] |
32 |
ITGB2 |
Integrin beta-2 |
[218] |
2.04[219] |
3.18[220] |
-3.95[221] |
-3.91[222] |
-6.04[223] |
0.27[224] |
33 |
TGFB2 |
Transforming growth factor beta-2 |
[225] |
-3.54[226] |
-6.32[227] |
0.64[228] |
4.74[229] |
3.19[230] |
-3.81[231] |
34 |
IL1B |
Interleukin-1 beta |
[232] |
-7.95[233] |
-8.06[234] |
-2.59[235] |
-2.31[236] |
3.13[237] |
-6.24[238] |
35 |
HLA-DPB1 |
HLA class II histocompatibility antigen, DP beta 1 chain |
[239] |
-8.29[240] |
-9.61[241] |
[242] |
-2.66[243] |
-0.81[244] |
-0.53[245] |
36 |
HLA-DMA |
HLA class II histocompatibility antigen, DM alpha chain |
[246] |
-1.93[247] |
-2.06[248] |
-1.60[249] |
0.59[250] |
-0.50[251] |
-1.47[252] |
37 |
TGFB1 |
Transforming growth factor beta-1 |
[253] |
4.22[254] |
2.93[255] |
1.34[256] |
5.12[257] |
4.20[258] |
-2.27[259] |
38 |
HLA-DQA1 |
HLA class II histocompatibility antigen, DQ alpha 1 chain |
[260] |
[261] |
[262] |
[263] |
-5.50[264] |
-9.28[265] |
-1.91[266] |
39 |
HLA-DQB1 |
HLA class II histocompatibility antigen, DQ beta 1 chain |
[267] |
-4.20[268] |
[269] |
[270] |
-2.51[271] |
[272] |
-2.01[273] |
40 |
NCF1 |
Neutrophil cytosol factor 1 |
[274] |
-6.41[275] |
-8.72[276] |
[277] |
[278] |
-8.16[279] |
-3.84[280] |
41 |
TLR2 |
Toll-like receptor 2 |
[281] |
-2.80[282] |
-1.63[283] |
-7.47[284] |
-3.69[285] |
2.92[286] |
0.20[287] |
42 |
HLA-DMB |
HLA class II histocompatibility antigen, DM beta chain |
[288] |
-6.42[289] |
-7.55[290] |
2.69[291] |
0.32[292] |
-2.28[293] |
-1.18[294] |
43 |
IRAK4 |
Interleukin-1 receptor-associated kinase 4 |
[295] |
1.00[296] |
2.12[297] |
3.55[298] |
2.70[299] |
2.31[300] |
0.74[301] |
44 |
TGFB3 |
Transforming growth factor beta-3 |
[302] |
-0.79[303] |
-1.92[304] |
-1.00[305] |
1.45[306] |
0.24[307] |
-0.59[308] |
45 |
HLA-DQA2 |
HLA class II histocompatibility antigen, DQ alpha 2 chain |
[309] |
[310] |
[311] |
[312] |
-7.46[313] |
[314] |
-4.52[315] |
46 |
TRAF6 |
TNF receptor-associated factor 6 |
[316] |
1.84[317] |
1.48[318] |
3.20[319] |
2.94[320] |
2.25[321] |
1.87[322] |
47 |
FCGR2A |
Low affinity immunoglobulin gamma Fc region receptor II-a |
[323] |
-5.63[324] |
[325] |
-2.01[326] |
-1.28[327] |
-3.93[328] |
0.15[329] |
48 |
JAK2 |
Tyrosine-protein kinase JAK2 |
[330] |
0.97[331] |
0.72[332] |
1.43[333] |
2.04[334] |
2.49[335] |
1.66[336] |
49 |
MAPK12 |
Mitogen-activated protein kinase 12 |
[337] |
3.57[338] |
2.98[339] |
5.25[340] |
2.76[341] |
3.87[342] |
-1.95[343] |
50 |
NOS2 |
Nitric oxide synthase, inducible |
[344] |
0.77[345] |
[346] |
-4.57[347] |
-3.58[348] |
-4.61[349] |
-8.35[350] |
51 |
NCF4 |
Neutrophil cytosol factor 4 |
[351] |
-5.02[352] |
-7.58[353] |
[354] |
-6.77[355] |
[356] |
-0.13[357] |
52 |
TLR4 |
Toll-like receptor 4 |
[358] |
1.02[359] |
-4.38[360] |
-4.12[361] |
-3.82[362] |
6.46[363] |
3.42[364] |
53 |
IL10 |
Interleukin-10 |
[365] |
-1.12[366] |
-1.62[367] |
-0.29[368] |
-0.70[369] |
-1.31[370] |
-2.63[371] |
54 |
ITGAM |
Integrin alpha-M |
[372] |
-1.65[373] |
-4.45[374] |
-2.07[375] |
-1.31[376] |
-3.88[377] |
1.87[378] |
55 |
MAPK11 |
Mitogen-activated protein kinase 11 |
[379] |
0.58[380] |
0.22[381] |
0.49[382] |
1.63[383] |
3.49[384] |
-0.88[385] |
56 |
FCGR1A |
High affinity immunoglobulin gamma Fc receptor I |
[386] |
[387] |
[388] |
[389] |
-5.64[390] |
[391] |
-1.57[392] |
57 |
PRKCB |
Protein kinase C beta type |
[393] |
-6.07[394] |
-5.12[395] |
[396] |
3.76[397] |
-1.69[398] |
2.49[399] |
58 |
HLA-DOA |
HLA class II histocompatibility antigen, DO alpha chain |
[400] |
-0.10[401] |
-2.34[402] |
-2.58[403] |
-1.52[404] |
0.77[405] |
0.22[406] |
59 |
ITGA4 |
Integrin alpha-4 |
[407] |
-2.90[408] |
[409] |
0.49[410] |
8.87[411] |
5.37[412] |
2.39[413] |
60 |
IFNG |
Interferon gamma |
[414] |
[415] |
[416] |
[417] |
0.59[418] |
[419] |
-3.34[420] |
61 |
IL12A |
Interleukin-12 subunit alpha |
[421] |
-0.66[422] |
[423] |
1.74[424] |
-0.27[425] |
1.39[426] |
-4.22[427] |
62 |
CR1 |
Complement receptor type 1 |
[428] |
-1.81[429] |
-1.51[430] |
0.02[431] |
-0.84[432] |
-1.55[433] |
4.00[434] |
63 |
TNF |
Tumor necrosis factor |
[435] |
1.85[436] |
-0.53[437] |
-3.98[438] |
-0.94[439] |
-4.31[440] |
-2.93[441] |
64 |
HLA-DOB |
HLA class II histocompatibility antigen, DO beta chain |
[442] |
-1.12[443] |
[444] |
[445] |
2.92[446] |
1.13[447] |
-0.66[448] |
65 |
IL1A |
Interleukin-1 alpha |
[449] |
0.32[450] |
-0.33[451] |
-0.35[452] |
0.64[453] |
7.25[454] |
-2.63[455] |
66 |
PTGS2 |
Prostaglandin G/H synthase 2 |
[456] |
[457] |
-2.12[458] |
-0.71[459] |
4.14[460] |
9.82[461] |
1.79[462] |
67 |
FCGR3B |
Low affinity immunoglobulin gamma Fc region receptor III-B |
[463] |
[464] |
[465] |
[466] |
[467] |
-1.00[468] |
3.62[469] |
68 |
IL4 |
Interleukin-4 |
[470] |
[471] |
[472] |
[473] |
[474] |
[475] |
[476] |
69 |
FCGR2C |
Low affinity immunoglobulin gamma Fc region receptor II-c |
[477] |
[478] |
[479] |
[480] |
[481] |
[482] |
[483] |
70 |
HLA-DRB4 |
HLA class II histocompatibility antigen, DR beta 4 chain |
[484] |
[485] |
[486] |
[487] |
[488] |
[489] |
[490] |
71 |
IL12B |
Interleukin-12 subunit beta |
[491] |
[492] |
[493] |
[494] |
[495] |
[496] |
[497] |
72 |
HLA-DRB3 |
HLA class II histocompatibility antigen, DR beta 3 chain |
[498] |
[499] |
[500] |
[501] |
[502] |
[503] |
[504] |
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