KEGG_HEDGEHOG_SIGNALING_PATHWAY | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | CSNK1A1 | Casein kinase I isoform alpha | [1] | -0.59[2] | -0.49[3] | -0.94[4] | -0.26[5] | -0.36[6] | 0.39[7] |
2 | CSNK1D | Casein kinase I isoform delta | [8] | 0.24[9] | 0.12[10] | -0.19[11] | -0.07[12] | -0.73[13] | -0.90[14] |
3 | PRKACA | cAMP-dependent protein kinase catalytic subunit alpha | [15] | -1.10[16] | -1.16[17] | -1.38[18] | -1.56[19] | -1.17[20] | -1.09[21] |
4 | WNT11 | Protein Wnt-11 | [22] | -2.36[23] | -7.95[24] | -7.15[25] | -7.62[26] | -8.25[27] | -3.39[28] |
5 | CSNK1G2 | Casein kinase I isoform gamma-2 | [29] | 0.45[30] | 0.53[31] | 0.22[32] | -1.09[33] | -0.57[34] | -1.14[35] |
6 | CSNK1E | Casein kinase I isoform epsilon | [36] | 0.43[37] | 0.18[38] | 0.61[39] | -0.62[40] | 0.25[41] | -1.13[42] |
7 | FBXW11 | F-box/WD repeat-containing protein 11 | [43] | 0.44[44] | 0.47[45] | 1.00[46] | 0.43[47] | 0.15[48] | 0.64[49] |
8 | BMP2 | Bone morphogenetic protein 2 | [50] | -5.92[51] | -8.93[52] | -0.06[53] | -2.98[54] | -2.93[55] | -2.49[56] |
9 | GSK3B | Glycogen synthase kinase-3 beta | [57] | 0.33[58] | 0.08[59] | 0.43[60] | 0.72[61] | 0.35[62] | 0.86[63] |
10 | CSNK1G3 | Casein kinase I isoform gamma-3 | [64] | -1.12[65] | 0.44[66] | -0.30[67] | 0.18[68] | -0.21[69] | 1.00[70] |
11 | SMO | Smoothened homolog | [71] | 0.24[72] | 0.73[73] | 0.66[74] | 0.05[75] | -0.86[76] | -0.06[77] |
12 | PRKACB | cAMP-dependent protein kinase catalytic subunit beta | [78] | -1.77[79] | -0.88[80] | 0.18[81] | 1.14[82] | -0.20[83] | 1.40[84] |
13 | RAB23 | Ras-related protein Rab-23 | [85] | -0.63[86] | -0.09[87] | -0.76[88] | 0.89[89] | 0.69[90] | -0.68[91] |
14 | BTRC | F-box/WD repeat-containing protein 1A | [92] | 0.48[93] | 1.39[94] | 0.78[95] | -0.33[96] | 0.01[97] | 1.04[98] |
15 | BMP4 | Bone morphogenetic protein 4 | [99] | 3.55[100] | 2.90[101] | -0.40[102] | 0.91[103] | -1.43[104] | -1.49[105] |
16 | STK36 | Serine/threonine-protein kinase 36 | [106] | 0.50[107] | 1.40[108] | 0.16[109] | 0.25[110] | 0.24[111] | 0.92[112] |
17 | SUFU | Suppressor of fused homolog | [113] | 0.52[114] | 0.66[115] | 1.37[116] | 0.13[117] | 0.44[118] | 0.06[119] |
18 | CSNK1G1 | Casein kinase I isoform gamma-1 | [120] | 0.89[121] | 1.23[122] | 1.43[123] | 1.36[124] | 1.07[125] | 1.37[126] |
19 | SHH | Sonic hedgehog protein | [127] | -0.55[128] | -0.59[129] | -0.73[130] | -8.27[131] | -8.61[132] | -0.18[133] |
20 | WNT3 | Proto-oncogene Wnt-3 | [134] | -1.32[135] | -0.25[136] | -2.40[137] | -1.66[138] | -3.19[139] | -0.13[140] |
21 | WNT5B | Protein Wnt-5b | [141] | -5.87[142] | -6.93[143] | -0.60[144] | 0.48[145] | -3.53[146] | -1.51[147] |
22 | PRKX | cAMP-dependent protein kinase catalytic subunit PRKX | [148] | -2.58[149] | -2.69[150] | 2.01[151] | 0.16[152] | 1.50[153] | 1.14[154] |
23 | BMP6 | Bone morphogenetic protein 6 | [155] | -0.78[156] | -3.38[157] | -4.70[158] | -1.86[159] | -3.31[160] | 1.27[161] |
24 | WNT4 | Protein Wnt-4 | [162] | -4.62[163] | -3.65[164] | -4.98[165] | -2.45[166] | -3.98[167] | -0.09[168] |
25 | WNT5A | Protein Wnt-5a | [169] | -4.13[170] | -4.00[171] | -3.06[172] | 5.50[173] | 6.88[174] | 1.01[175] |
26 | PTCH1 | Protein patched homolog 1 | [176] | 1.70[177] | 2.06[178] | 3.19[179] | 2.24[180] | 1.38[181] | 2.54[182] |
27 | BMP8B | Bone morphogenetic protein 8B | [183] | -0.85[184] | -0.36[185] | 0.93[186] | -1.35[187] | -1.89[188] | -0.35[189] |
28 | BMP7 | Bone morphogenetic protein 7 | [190] | -2.42[191] | -1.50[192] | -1.90[193] | -1.73[194] | -2.31[195] | -1.46[196] |
29 | IHH | Indian hedgehog protein | [197] | 0.12[198] | -1.71[199] | 3.87[200] | -5.39[201] | -6.45[202] | -0.21[203] |
30 | WNT7B | Protein Wnt-7b | [204] | 1.75[205] | 0.05[206] | -0.42[207] | -0.76[208] | -1.90[209] | -1.13[210] |
31 | WNT9B | Protein Wnt-9b | [211] | -4.98[212] | -5.69[213] | -2.36[214] | [215] | [216] | -5.16[217] |
32 | ZIC2 | Zinc finger protein ZIC 2 | [218] | 1.54[219] | 1.34[220] | 2.74[221] | 0.84[222] | -6.39[223] | -3.15[224] |
33 | BMP8A | Bone morphogenetic protein 8A | [225] | -1.24[226] | 0.11[227] | 1.28[228] | -1.25[229] | 0.43[230] | 2.79[231] |
34 | WNT9A | Protein Wnt-9a | [232] | -0.89[233] | -3.89[234] | -4.90[235] | 0.14[236] | -2.26[237] | -2.93[238] |
35 | GLI1 | Zinc finger protein GLI1 | [239] | -2.58[240] | -2.62[241] | 0.39[242] | -2.18[243] | 0.22[244] | 0.66[245] |
36 | GAS1 | Growth arrest-specific protein 1 | [246] | -5.54[247] | [248] | -5.16[249] | -0.11[250] | 4.73[251] | 1.87[252] |
37 | LRP2 | Low-density lipoprotein receptor-related protein 2 | [253] | 1.37[254] | -1.85[255] | 6.61[256] | -3.37[257] | -3.83[258] | 5.92[259] |
38 | WNT2B | Protein Wnt-2b | [260] | -1.57[261] | -0.67[262] | -0.91[263] | 1.51[264] | 0.63[265] | 0.62[266] |
39 | WNT16 | Protein Wnt-16 | [267] | [268] | [269] | [270] | 0.25[271] | -3.82[272] | -0.15[273] |
40 | PTCH2 | Protein patched homolog 2 | [274] | 2.30[275] | 3.73[276] | -0.09[277] | -0.58[278] | 0.41[279] | 1.62[280] |
41 | WNT10A | Protein Wnt-10a | [281] | 0.32[282] | -2.91[283] | -5.84[284] | 2.45[285] | -3.51[286] | -1.79[287] |
42 | GLI2 | Zinc finger protein GLI2 | [288] | -0.29[289] | -3.72[290] | -2.21[291] | 7.38[292] | 6.36[293] | 2.58[294] |
43 | GLI3 | Transcriptional activator GLI3 | [295] | -2.16[296] | [297] | -1.31[298] | 7.84[299] | 6.01[300] | 3.85[301] |
44 | BMP5 | Bone morphogenetic protein 5 | [302] | -2.35[303] | [304] | -4.65[305] | 5.95[306] | -4.71[307] | 4.60[308] |
45 | WNT2 | Protein Wnt-2 | [309] | [310] | [311] | -3.04[312] | -0.16[313] | -4.29[314] | 5.92[315] |
46 | PRKACG | cAMP-dependent protein kinase catalytic subunit gamma | [316] | [317] | [318] | [319] | [320] | [321] | [322] |
47 | WNT6 | Protein Wnt-6 | [323] | [324] | [325] | [326] | [327] | [328] | [329] |
48 | WNT8A | Protein Wnt-8a | [330] | [331] | [332] | [333] | [334] | [335] | [336] |
49 | DHH | Desert hedgehog protein | [337] | [338] | [339] | [340] | [341] | [342] | [343] |
50 | WNT1 | Proto-oncogene Wnt-1 | [344] | [345] | [346] | [347] | [348] | [349] | [350] |
51 | WNT3A | Protein Wnt-3a | [351] | [352] | [353] | [354] | [355] | [356] | [357] |
52 | WNT10B | Protein Wnt-10b | [358] | [359] | [360] | [361] | [362] | [363] | [364] |
53 | WNT8B | Protein Wnt-8b | [365] | [366] | [367] | [368] | [369] | [370] | [371] |
54 | HHIP | Hedgehog-interacting protein | [372] | [373] | [374] | [375] | [376] | [377] | [378] |
55 | WNT7A | Protein Wnt-7a | [379] | [380] | [381] | [382] | [383] | [384] | [385] |
56 | CSNK1A1L | Casein kinase I isoform alpha-like | [386] | [387] | [388] | [389] | [390] | [391] | [392] |