KEGG_GRAFT_VERSUS_HOST_DISEASE |
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Order |
Gene |
Description |
ref_hepatocyte |
HepG2 |
HepG2.C3A |
HuH.7 |
SNU475 |
THLE |
liver |
1 |
HLA-A |
HLA class I histocompatibility antigen, A-68 alpha chain |
[1] |
0.74[2] |
1.15[3] |
-2.05[4] |
0.06[5] |
-0.19[6] |
-0.92[7] |
2 |
HLA-C |
HLA class I histocompatibility antigen, Cw-17 alpha chain |
[8] |
-0.11[9] |
-0.62[10] |
-1.70[11] |
-0.72[12] |
0.10[13] |
-0.52[14] |
3 |
HLA-B |
HLA class I histocompatibility antigen, B-73 alpha chain |
[15] |
-1.08[16] |
-2.25[17] |
-3.81[18] |
0.72[19] |
0.48[20] |
-0.17[21] |
4 |
HLA-E |
HLA class I histocompatibility antigen, alpha chain E |
[22] |
0.09[23] |
0.10[24] |
2.45[25] |
0.21[26] |
-0.38[27] |
1.35[28] |
5 |
HLA-DRA |
HLA class II histocompatibility antigen, DR alpha chain |
[29] |
-11.35[30] |
[31] |
-9.42[32] |
-5.43[33] |
-6.59[34] |
0.60[35] |
6 |
HLA-DRB1 |
HLA class II histocompatibility antigen, DRB1-15 beta chain |
[36] |
-6.52[37] |
[38] |
[39] |
-5.79[40] |
-10.09[41] |
-0.49[42] |
7 |
FAS |
Tumor necrosis factor receptor superfamily member 6 |
[43] |
0.32[44] |
1.26[45] |
-3.97[46] |
-1.43[47] |
-0.14[48] |
-0.56[49] |
8 |
HLA-DPA1 |
HLA class II histocompatibility antigen, DP alpha 1 chain |
[50] |
-5.02[51] |
-8.36[52] |
[53] |
-4.78[54] |
-5.86[55] |
0.88[56] |
9 |
HLA-DRB5 |
HLA class II histocompatibility antigen, DR beta 5 chain |
[57] |
-9.17[58] |
[59] |
[60] |
-8.04[61] |
[62] |
-4.68[63] |
10 |
HLA-F |
HLA class I histocompatibility antigen, alpha chain F |
[64] |
-0.53[65] |
-1.83[66] |
-3.19[67] |
1.60[68] |
0.50[69] |
1.19[70] |
11 |
HLA-G |
HLA class I histocompatibility antigen, alpha chain G |
[71] |
-1.10[72] |
-1.95[73] |
-3.86[74] |
-1.01[75] |
-6.36[76] |
-2.63[77] |
12 |
IL1B |
Interleukin-1 beta |
[78] |
-6.78[79] |
-6.48[80] |
0.62[81] |
-3.27[82] |
3.08[83] |
-4.03[84] |
13 |
HLA-DPB1 |
HLA class II histocompatibility antigen, DP beta 1 chain |
[85] |
-7.12[86] |
-8.03[87] |
[88] |
-3.62[89] |
-0.86[90] |
1.68[91] |
14 |
HLA-DMA |
HLA class II histocompatibility antigen, DM alpha chain |
[92] |
-0.76[93] |
-0.48[94] |
1.60[95] |
-0.37[96] |
-0.55[97] |
0.74[98] |
15 |
HLA-DQA1 |
HLA class II histocompatibility antigen, DQ alpha 1 chain |
[99] |
[100] |
[101] |
[102] |
-6.46[103] |
-9.33[104] |
0.30[105] |
16 |
HLA-DQB1 |
HLA class II histocompatibility antigen, DQ beta 1 chain |
[106] |
-3.04[107] |
[108] |
[109] |
-3.47[110] |
[111] |
0.20[112] |
17 |
HLA-DMB |
HLA class II histocompatibility antigen, DM beta chain |
[113] |
-5.26[114] |
-5.97[115] |
5.89[116] |
-0.64[117] |
-2.33[118] |
1.03[119] |
18 |
IL6 |
Interleukin-6 |
[120] |
-6.53[121] |
[122] |
0.02[123] |
-0.54[124] |
2.75[125] |
[126] |
19 |
HLA-DQA2 |
HLA class II histocompatibility antigen, DQ alpha 2 chain |
[127] |
[128] |
[129] |
[130] |
-8.42[131] |
[132] |
-2.31[133] |
20 |
KLRD1 |
Natural killer cells antigen CD94 |
[134] |
-1.07[135] |
0.17[136] |
3.11[137] |
-1.24[138] |
-0.73[139] |
1.28[140] |
21 |
PRF1 |
Perforin-1 |
[141] |
5.87[142] |
-1.19[143] |
-2.10[144] |
-7.39[145] |
-5.27[146] |
2.62[147] |
22 |
CD86 |
T-lymphocyte activation antigen CD86 |
[148] |
[149] |
[150] |
0.15[151] |
-3.78[152] |
-5.03[153] |
2.52[154] |
23 |
GZMB |
Granzyme B |
[155] |
-2.70[156] |
[157] |
[158] |
[159] |
[160] |
0.46[161] |
24 |
HLA-DOA |
HLA class II histocompatibility antigen, DO alpha chain |
[162] |
1.07[163] |
-0.76[164] |
0.62[165] |
-2.49[166] |
0.72[167] |
2.43[168] |
25 |
IFNG |
Interferon gamma |
[169] |
[170] |
[171] |
[172] |
-0.38[173] |
[174] |
-1.13[175] |
26 |
TNF |
Tumor necrosis factor |
[176] |
3.02[177] |
1.04[178] |
-0.78[179] |
-1.90[180] |
-4.36[181] |
-0.73[182] |
27 |
CD28 |
T-cell-specific surface glycoprotein CD28 |
[183] |
-2.09[184] |
-1.05[185] |
1.75[186] |
-2.03[187] |
-1.31[188] |
2.29[189] |
28 |
HLA-DOB |
HLA class II histocompatibility antigen, DO beta chain |
[190] |
0.05[191] |
[192] |
[193] |
1.96[194] |
1.08[195] |
1.55[196] |
29 |
FASLG |
Tumor necrosis factor ligand superfamily member 6 |
[197] |
-1.90[198] |
0.14[199] |
-1.06[200] |
[201] |
[202] |
1.75[203] |
30 |
IL1A |
Interleukin-1 alpha |
[204] |
1.49[205] |
1.25[206] |
2.85[207] |
-0.32[208] |
7.20[209] |
-0.42[210] |
31 |
CD80 |
T-lymphocyte activation antigen CD80 |
[211] |
[212] |
[213] |
-0.40[214] |
-0.84[215] |
-1.13[216] |
3.79[217] |
32 |
KIR3DL2 |
Killer cell immunoglobulin-like receptor 3DL2 |
[218] |
[219] |
[220] |
[221] |
[222] |
[223] |
0.62[224] |
33 |
KLRC1 |
NKG2-A/NKG2-B type II integral membrane protein |
[225] |
4.14[226] |
2.77[227] |
[228] |
0.34[229] |
1.95[230] |
5.09[231] |
34 |
KIR2DL1 |
Killer cell immunoglobulin-like receptor 2DL1 |
[232] |
[233] |
[234] |
[235] |
[236] |
-0.17[237] |
3.24[238] |
35 |
KIR2DL3 |
Killer cell immunoglobulin-like receptor 2DL3 |
[239] |
[240] |
[241] |
[242] |
[243] |
[244] |
2.58[245] |
36 |
HLA-DRB3 |
HLA class II histocompatibility antigen, DR beta 3 chain |
[246] |
[247] |
[248] |
[249] |
[250] |
[251] |
[252] |
37 |
HLA-DRB4 |
HLA class II histocompatibility antigen, DR beta 4 chain |
[253] |
[254] |
[255] |
[256] |
[257] |
[258] |
[259] |
38 |
KIR2DL2 |
Killer cell immunoglobulin-like receptor 2DL2 |
[260] |
[261] |
[262] |
[263] |
[264] |
[265] |
[266] |
39 |
KIR3DL1 |
Killer cell immunoglobulin-like receptor 3DL1 |
[267] |
[268] |
[269] |
[270] |
[271] |
[272] |
[273] |
40 |
IL2 |
Interleukin-2 |
[274] |
[275] |
[276] |
[277] |
[278] |
[279] |
[280] |
41 |
KIR2DL5A |
Killer cell immunoglobulin-like receptor 2DL5A |
[281] |
[282] |
[283] |
[284] |
[285] |
[286] |
[287] |
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