KEGG_GLYOXYLATE_AND_DICARBOXYLATE_METABOLISM Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 GRHPR Glyoxylate reductase/hydroxypyruvate reductase [1] -2.02[2] -2.00[3] -0.67[4] -1.91[5] -1.64[6] -0.71[7]
2 MDH2 Malate dehydrogenase, mitochondrial [8] -0.25[9] -0.97[10] -0.18[11] 0.10[12] -0.81[13] -0.46[14]
3 MDH1 Malate dehydrogenase, cytoplasmic [15] 0.21[16] 0.59[17] 0.33[18] 1.14[19] 0.43[20] -0.58[21]
4 HAO1 Hydroxyacid oxidase 1 [22] -9.50[23] [24] [25] [26] [27] -0.15[28]
5 MTHFD1 C-1-tetrahydrofolate synthase, cytoplasmic [29] 0.50[30] -0.27[31] -0.08[32] 0.75[33] 1.08[34] 0.98[35]
6 HAO2 Hydroxyacid oxidase 2 [36] -10.04[37] [38] -6.99[39] -13.08[40] [41] 0.51[42]
7 GLYCTK Glycerate kinase [43] -1.04[44] -0.12[45] 0.44[46] -3.26[47] -3.74[48] 0.79[49]
8 ACO1 Cytoplasmic aconitate hydratase [50] -0.75[51] -0.89[52] -0.39[53] 0.05[54] 1.58[55] 1.12[56]
9 AFMID Kynurenine formamidase [57] 0.19[58] 1.21[59] -0.17[60] -2.49[61] -2.28[62] 0.47[63]
10 ACO2 Aconitate hydratase, mitochondrial [64] 0.62[65] 0.46[66] 0.90[67] 0.62[68] 0.45[69] 0.24[70]
11 HYI Putative hydroxypyruvate isomerase [71] [72] [73] [74] [75] [76] [77]
12 CS Citrate synthase, mitochondrial [78] 3.18[79] 2.72[80] 2.48[81] 2.87[82] 2.60[83] 0.32[84]
13 MTHFD1L Monofunctional C1-tetrahydrofolate synthase, mitochondrial [85] 2.82[86] 2.22[87] 2.23[88] 2.33[89] 1.92[90] -1.86[91]
14 MTHFD2 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial 3.75[92] 4.35[93] 3.32[94] 1.39[95] 3.78[96] -2.34[97]
15 PGP Glycerol-3-phosphate phosphatase [98] 1.98[99] 2.19[100] 2.46[101] 1.95[102] 2.28[103] 0.10[104]
16 MTHFD2L Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 -0.60[105] 1.15[106] -0.32[107] 0.78[108] 1.00[109] 2.18[110]
[1]
ref_hepatocyte GRHPR
Mean 132
Standard deviation 1.2e+02
Values 54 65 1.9e+02 33 3.1e+02
[2]
HepG2 GRHPR
Mean 39.9
Standard deviation 1.2
Values 41 39
[3]
HepG2.C3A GRHPR
Mean 42.2
Standard deviation 5.7
Values 46 38
[4]
HuH.7 GRHPR
Mean 82.2
Standard deviation 15
Values 77 71 99
[5]
SNU475 GRHPR
Mean 20.5
Standard deviation 4.5
Values 24 17
[6]
THLE GRHPR
Mean 35
Standard deviation 2
Values 34 36
[7]
liver GRHPR
Mean 113
Standard deviation 66
Values 48 2e+02 98 1e+02
[8]
ref_hepatocyte MDH2
Mean 104
Standard deviation 75
Values 38 53 2.2e+02 77 1.3e+02
[9]
HepG2 MDH2
Mean 107
Standard deviation 16
Values 1.2e+02 96
[10]
HepG2.C3A MDH2
Mean 67.7
Standard deviation 5.8
Values 72 64
[11]
HuH.7 MDH2
Mean 91.1
Standard deviation 31
Values 1.2e+02 57 98
[12]
SNU475 MDH2
Mean 64.7
Standard deviation 14
Values 74 55
[13]
THLE MDH2
Mean 49
Standard deviation 8.8
Values 43 55
[14]
liver MDH2
Mean 107
Standard deviation 92
Values 26 1.7e+02 2e+02 29
[15]
ref_hepatocyte MDH1
Mean 74.5
Standard deviation 43
Values 99 52 1e+02 9.2 1.1e+02
[16]
HepG2 MDH1
Mean 106
Standard deviation 36
Values 80 1.3e+02
[17]
HepG2.C3A MDH1
Mean 144
Standard deviation 49
Values 1.1e+02 1.8e+02
[18]
HuH.7 MDH1
Mean 93.1
Standard deviation 25
Values 96 67 1.2e+02
[19]
SNU475 MDH1
Mean 95.9
Standard deviation 44
Values 1.3e+02 65
[20]
THLE MDH1
Mean 83.2
Standard deviation 9.4
Values 77 90
[21]
liver MDH1
Mean 70.6
Standard deviation 50
Values 34 1.2e+02 1.1e+02 22
[22]
ref_hepatocyte HAO1
Mean 66.1
Standard deviation 88
Values 0 10 1.2e+02 5.6 2e+02
[23]
HepG2 HAO1
Mean 0.112
Standard deviation 0.078
Values 0.057 0.17
[24]
HepG2.C3A HAO1
Mean 0
Standard deviation 0
Values 0 0
[25]
HuH.7 HAO1
Mean 0
Standard deviation 0
Values 0 0 0
[26]
SNU475 HAO1
Mean 0
Standard deviation 0
Values 0 0
[27]
THLE HAO1
Mean 0
Standard deviation 0
Values 0 0
[28]
liver HAO1
Mean 84
Standard deviation 33
Values 74 1.3e+02 81 52
[29]
ref_hepatocyte MTHFD1
Mean 38.3
Standard deviation 33
Values 17 24 54 7.6 88
[30]
HepG2 MTHFD1
Mean 66.6
Standard deviation 5.5
Values 63 70
[31]
HepG2.C3A MTHFD1
Mean 40.6
Standard deviation 9.4
Values 34 47
[32]
HuH.7 MTHFD1
Mean 36.1
Standard deviation 17
Values 50 17 42
[33]
SNU475 MTHFD1
Mean 37.7
Standard deviation 1.4
Values 39 37
[34]
THLE MTHFD1
Mean 67.1
Standard deviation 15
Values 56 78
[35]
liver MTHFD1
Mean 106
Standard deviation 16
Values 99 90 1.3e+02 1.1e+02
[36]
ref_hepatocyte HAO2
Mean 37.5
Standard deviation 50
Values 0 0.48 86 1.8 99
[37]
HepG2 HAO2
Mean 0.0437
Standard deviation 0.005
Values 0.04 0.047
[38]
HepG2.C3A HAO2
Mean 0
Standard deviation 0
Values 0 0
[39]
HuH.7 HAO2
Mean 0.294
Standard deviation 0.062
Values 0.25 0.37 0.26
[40]
SNU475 HAO2
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[41]
THLE HAO2
Mean 0
Standard deviation 0
Values 0 0
[42]
liver HAO2
Mean 75.6
Standard deviation 46
Values 38 1.3e+02 36 1e+02
[43]
ref_hepatocyte GLYCTK
Mean 32.5
Standard deviation 39
Values 12 1.5 52 3.9 93
[44]
HepG2 GLYCTK
Mean 19.4
Standard deviation 9.8
Values 12 26
[45]
HepG2.C3A GLYCTK
Mean 38.2
Standard deviation 1.6
Values 37 39
[46]
HuH.7 GLYCTK
Mean 43.9
Standard deviation 10
Values 40 36 56
[47]
SNU475 GLYCTK
Mean 1.99
Standard deviation 0.75
Values 1.5 2.5
[48]
THLE GLYCTK
Mean 2
Standard deviation 0.78
Values 1.4 2.6
[49]
liver GLYCTK
Mean 79.2
Standard deviation 27
Values 55 1.1e+02 85 61
[50]
ref_hepatocyte ACO1
Mean 31.6
Standard deviation 14
Values 23 36 42 12 46
[51]
HepG2 ACO1
Mean 23.1
Standard deviation 6.4
Values 19 28
[52]
HepG2.C3A ACO1
Mean 21.8
Standard deviation 0.47
Values 22 22
[53]
HuH.7 ACO1
Mean 24.1
Standard deviation 2.5
Values 27 22 24
[54]
SNU475 ACO1
Mean 19.1
Standard deviation 1.3
Values 20 18
[55]
THLE ACO1
Mean 78.6
Standard deviation 31
Values 57 1e+02
[56]
liver ACO1
Mean 97.1
Standard deviation 28
Values 1.1e+02 81 1.3e+02 69
[57]
ref_hepatocyte AFMID
Mean 27.8
Standard deviation 20
Values 41 7.6 51 4.8 35
[58]
HepG2 AFMID
Mean 39
Standard deviation 12
Values 31 47
[59]
HepG2.C3A AFMID
Mean 82.2
Standard deviation 14
Values 92 72
[60]
HuH.7 AFMID
Mean 24.5
Standard deviation 7.7
Values 25 17 32
[61]
SNU475 AFMID
Mean 2.9
Standard deviation 0.18
Values 3 2.8
[62]
THLE AFMID
Mean 4.73
Standard deviation 0.045
Values 4.7 4.8
[63]
liver AFMID
Mean 54.5
Standard deviation 41
Values 23 1.1e+02 54 28
[64]
ref_hepatocyte ACO2
Mean 19
Standard deviation 5.5
Values 20 14 26 13 22
[65]
HepG2 ACO2
Mean 36.1
Standard deviation 0.091
Values 36 36
[66]
HepG2.C3A ACO2
Mean 33.5
Standard deviation 6
Values 38 29
[67]
HuH.7 ACO2
Mean 35.4
Standard deviation 5.1
Values 41 33 32
[68]
SNU475 ACO2
Mean 17.1
Standard deviation 6.3
Values 22 13
[69]
THLE ACO2
Mean 21.5
Standard deviation 7.4
Values 16 27
[70]
liver ACO2
Mean 31.8
Standard deviation 8.4
Values 29 25 44 29
[71]
ref_hepatocyte HYI
Mean 17
Standard deviation 12
Values 0 31 22 12 20
[72]
HepG2 HYI
Missing
[73]
HepG2.C3A HYI
Missing
[74]
HuH.7 HYI
Missing
[75]
SNU475 HYI
Missing
[76]
THLE HYI
Missing
[77]
liver HYI
Missing
[78]
ref_hepatocyte CS
Mean 15.3
Standard deviation 5.2
Values 23 9.8 13 19 12
[79]
HepG2 CS
Mean 170
Standard deviation 16
Values 1.6e+02 1.8e+02
[80]
HepG2.C3A CS
Mean 129
Standard deviation 6.5
Values 1.3e+02 1.2e+02
[81]
HuH.7 CS
Mean 85.2
Standard deviation 12
Values 96 73 86
[82]
SNU475 CS
Mean 65.5
Standard deviation 9.6
Values 72 59
[83]
THLE CS
Mean 76.6
Standard deviation 19
Values 63 90
[84]
liver CS
Mean 26.9
Standard deviation 9.6
Values 18 31 38 20
[85]
ref_hepatocyte MTHFD1L
Mean 5.11
Standard deviation 3.9
Values 4.8 6.5 3.2 11 0.36
[86]
HepG2 MTHFD1L
Mean 44.3
Standard deviation 12
Values 53 36
[87]
HepG2.C3A MTHFD1L
Mean 30.6
Standard deviation 12
Values 39 22
[88]
HuH.7 MTHFD1L
Mean 23.9
Standard deviation 6.6
Values 30 17 26
[89]
SNU475 MTHFD1L
Mean 15
Standard deviation 1.1
Values 14 16
[90]
THLE MTHFD1L
Mean 16
Standard deviation 2
Values 15 17
[91]
liver MTHFD1L
Mean 1.99
Standard deviation 0.21
Values 2 2.2 1.7 2.1
[92]
ref_hepatocyte MTHFD2
Mean 4.93
Standard deviation 5.2
Values 14 1.1 3.3 5.2 1.3
[93]
HepG2 MTHFD2
Mean 81.4
Standard deviation 25
Values 99 64
[94]
HepG2.C3A MTHFD2
Mean 129
Standard deviation 63
Values 1.7e+02 84
[95]
HuH.7 MTHFD2
Mean 49.2
Standard deviation 11
Values 55 37 55
[96]
SNU475 MTHFD2
Mean 7.54
Standard deviation 0.064
Values 7.6 7.5
[97]
THLE MTHFD2
Mean 56.2
Standard deviation 0.51
Values 56 57
[98]
liver MTHFD2
Mean 1.38
Standard deviation 0.47
Values 1.2 2.1 1 1.2
[99]
ref_hepatocyte PGP
Mean 3.09
Standard deviation 1.6
Values 1.6 1.7 4.3 5.3 2.6
[100]
HepG2 PGP
Mean 15
Standard deviation 1.8
Values 14 16
[101]
HepG2.C3A PGP
Mean 18
Standard deviation 4.7
Values 15 21
[102]
HuH.7 PGP
Mean 16.9
Standard deviation 7.9
Values 16 9.4 25
[103]
SNU475 PGP
Mean 6.96
Standard deviation 0.86
Values 6.4 7.6
[104]
THLE PGP
Mean 12.5
Standard deviation 0.84
Values 12 13
[105]
liver PGP
Mean 4.68
Standard deviation 1.2
Values 4.5 4.4 6.3 3.5
[106]
ref_hepatocyte MTHFD2L
Mean 0.936
Standard deviation 0.65
Values 0.6 0.5 0.55 0.99 2
[107]
HepG2 MTHFD2L
Mean 0.759
Standard deviation 0.11
Values 0.68 0.84
[108]
HepG2.C3A MTHFD2L
Mean 2.66
Standard deviation 0.36
Values 2.4 2.9
[109]
HuH.7 MTHFD2L
Mean 0.745
Standard deviation 0.26
Values 0.55 1 0.65
[110]
SNU475 MTHFD2L
Mean 0.939
Standard deviation 0.43
Values 0.64 1.2
[111]
THLE MTHFD2L
Mean 1.55
Standard deviation 0.053
Values 1.6 1.5
[112]
liver MTHFD2L
Mean 5.97
Standard deviation 3.1
Values 10 6.3 2.6 5