KEGG_GLUTATHIONE_METABOLISM Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 MGST1 Microsomal glutathione S-transferase 1 [1] -2.68[2] -3.11[3] -2.32[4] -2.83[5] -1.21[6] 0.05[7]
2 GSTA1 Glutathione S-transferase A1 [8] -4.06[9] -7.92[10] -1.83[11] -6.62[12] -10.52[13] -2.69[14]
3 GPX2 Glutathione peroxidase 2 [15] 0.72[16] -0.04[17] -2.30[18] -9.76[19] -9.01[20] 0.38[21]
4 GPX4 Phospholipid hydroperoxide glutathione peroxidase, mitochondrial [22] -0.23[23] 0.08[24] -0.34[25] -1.26[26] -0.74[27] -0.87[28]
5 GSTA2 Glutathione S-transferase A2 [29] -5.17[30] -7.75[31] -3.47[32] -8.05[33] -10.66[34] -2.50[35]
6 GPX1 Glutathione peroxidase 1 [36] 0.05[37] -0.36[38] -0.10[39] -0.87[40] 1.02[41] -0.61[42]
7 IDH2 Isocitrate dehydrogenase [NADP], mitochondrial [43] -0.46[44] -0.89[45] -0.56[46] -1.42[47] -1.83[48] 0.62[49]
8 GSTO1 Glutathione S-transferase omega-1 [50] -0.37[51] 0.26[52] -0.37[53] -2.77[54] 0.33[55] -0.28[56]
9 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic [57] 1.06[58] 1.72[59] 2.68[60] -0.16[61] -0.22[62] 0.44[63]
10 GSTK1 Glutathione S-transferase kappa 1 [64] -1.45[65] -0.96[66] -0.83[67] -1.73[68] -1.37[69] -0.10[70]
11 PGD 6-phosphogluconate dehydrogenase, decarboxylating [71] 0.44[72] 1.54[73] 0.77[74] 2.10[75] -0.03[76] -0.77[77]
12 GPX3 Glutathione peroxidase 3 [78] 1.88[79] 0.37[80] 0.22[81] -1.63[82] -5.39[83] 2.01[84]
13 ODC1 Ornithine decarboxylase [85] 1.35[86] 1.92[87] 0.61[88] -0.67[89] 1.15[90] -1.02[91]
14 MGST2 Microsomal glutathione S-transferase 2 [92] -0.50[93] 0.80[94] -1.01[95] -2.57[96] -1.67[97] -1.00[98]
15 ANPEP Aminopeptidase N [99] 0.57[100] 1.05[101] -1.97[102] -3.89[103] -0.32[104] 1.62[105]
16 GSTT1 Glutathione S-transferase theta-1 [106] -0.46[107] -0.36[108] -10.76[109] -11.60[110] -2.29[111] -0.07[112]
17 SMS Spermine synthase [113] 0.73[114] 0.42[115] 0.62[116] 0.66[117] 1.59[118] -1.68[119]
18 GSTZ1 Maleylacetoacetate isomerase [120] -2.39[121] -1.69[122] -2.19[123] -2.96[124] -2.00[125] -0.89[126]
19 LAP3 Cytosol aminopeptidase [127] 0.78[128] 1.03[129] 0.90[130] 0.06[131] 0.67[132] 1.57[133]
20 GSR Glutathione reductase, mitochondrial [134] 2.10[135] 1.62[136] 1.98[137] 2.20[138] 1.54[139] 0.07[140]
21 MGST3 Microsomal glutathione S-transferase 3 [141] -0.61[142] -0.67[143] -0.05[144] 0.56[145] 1.44[146] 0.72[147]
22 SRM Spermidine synthase [148] 1.04[149] 1.63[150] 0.06[151] 0.38[152] 1.61[153] -1.35[154]
23 GCLC Glutamate--cysteine ligase catalytic subunit [155] 1.22[156] 1.49[157] 0.16[158] 2.35[159] 0.56[160] 1.34[161]
24 GGCT Gamma-glutamylcyclotransferase [162] -0.38[163] 0.31[164] 1.27[165] -0.05[166] 0.89[167] -1.23[168]
25 GCLM Glutamate--cysteine ligase regulatory subunit [169] 0.60[170] -0.25[171] 0.10[172] 2.25[173] 1.35[174] 0.09[175]
26 GSS Glutathione synthetase [176] 2.27[177] 1.90[178] 1.13[179] 1.73[180] 2.05[181] 0.69[182]
27 TXNDC12 Thioredoxin domain-containing protein 12 [183] 2.37[184] 2.76[185] 1.94[186] 0.61[187] 2.59[188] 0.86[189]
28 GGT1 Glutathione hydrolase 1 proenzyme [190] 0.90[191] 0.55[192] 0.21[193] -0.78[194] -4.40[195] 1.64[196]
29 GSTA4 Glutathione S-transferase A4 [197] 0.39[198] 0.58[199] 1.65[200] 1.48[201] 0.54[202] -0.55[203]
30 RRM2 Ribonucleoside-diphosphate reductase subunit M2 [204] 3.15[205] 3.20[206] 2.58[207] 3.51[208] 4.47[209] 0.09[210]
31 GSTM4 Glutathione S-transferase Mu 4 [211] 0.77[212] 0.13[213] 0.21[214] 1.17[215] -1.09[216] 0.68[217]
32 RRM1 Ribonucleoside-diphosphate reductase large subunit [218] 3.05[219] 2.50[220] 3.08[221] 3.45[222] 4.49[223] 1.02[224]
33 G6PD Glucose-6-phosphate 1-dehydrogenase [225] 4.26[226] 2.21[227] 1.83[228] 5.91[229] 3.80[230] -1.61[231]
34 GSTP1 Glutathione S-transferase P [232] -2.39[233] -1.60[234] 5.98[235] 7.11[236] 5.79[237] 0.86[238]
35 RRM2B Ribonucleoside-diphosphate reductase subunit M2 B [239] 2.81[240] 2.89[241] 1.61[242] 2.41[243] 3.13[244] 1.38[245]
36 OPLAH 5-oxoprolinase [246] 2.51[247] 2.48[248] 0.84[249] 0.98[250] -0.14[251] 2.60[252]
37 GSTT2 Glutathione S-transferase theta-2 [253] -5.75[254] -7.79[255] -8.74[256] -3.56[257] -0.98[258] -2.65[259]
38 GSTM3 Glutathione S-transferase Mu 3 [260] 3.94[261] 3.20[262] 0.77[263] 4.27[264] 5.02[265] 2.44[266]
39 GPX7 Glutathione peroxidase 7 [267] 1.15[268] 1.93[269] 1.70[270] -2.26[271] 0.86[272] 0.46[273]
40 GGT7 Glutathione hydrolase 7 [274] 3.36[275] 3.60[276] 3.04[277] 3.37[278] 3.41[279] 1.29[280]
41 GSTO2 Glutathione S-transferase omega-2 [281] 0.33[282] 2.92[283] 0.38[284] -3.43[285] -0.34[286] -0.32[287]
42 GSTM2 Glutathione S-transferase Mu 2 [288] 1.96[289] 0.63[290] 2.31[291] 2.87[292] 3.15[293] 0.94[294]
43 GSTM1 Glutathione S-transferase Mu 1 [295] -0.74[296] -2.11[297] 3.94[298] 5.49[299] -1.99[300] 7.48[301]
44 GGT6 Glutathione hydrolase 6 [302] 1.90[303] 2.35[304] 0.50[305] 0.42[306] 0.62[307] 0.92[308]
45 GGT5 Glutathione hydrolase 5 proenzyme [309] 6.15[310] 3.45[311] -1.55[312] 5.31[313] 6.37[314] 6.56[315]
46 GSTA5 Glutathione S-transferase A5 [316] -5.50[317] [318] -5.11[319] [320] [321] [322]
47 GSTA3 Glutathione S-transferase A3 [323] -4.76[324] [325] -2.23[326] -0.60[327] [328] [329]
48 GPX6 Glutathione peroxidase 6 [330] [331] [332] [333] [334] [335] [336]
49 GPX5 Epididymal secretory glutathione peroxidase [337] [338] [339] [340] [341] [342] [343]
50 GSTM5 Glutathione S-transferase Mu 5 [344] [345] [346] [347] [348] [349] [350]
[1]
ref_hepatocyte MGST1
Mean 720
Standard deviation 4.5e+02
Values 2.4e+02 7.2e+02 7.8e+02 4.4e+02 1.4e+03
[2]
HepG2 MGST1
Mean 83.4
Standard deviation 3.7
Values 86 81
[3]
HepG2.C3A MGST1
Mean 58.5
Standard deviation 26
Values 40 77
[4]
HuH.7 MGST1
Mean 105
Standard deviation 17
Values 97 93 1.2e+02
[5]
SNU475 MGST1
Mean 70.5
Standard deviation 6
Values 66 75
[6]
THLE MGST1
Mean 128
Standard deviation 3.8
Values 1.3e+02 1.3e+02
[7]
liver MGST1
Mean 558
Standard deviation 6e+02
Values 62 9.8e+02 1.2e+03 31
[8]
ref_hepatocyte GSTA1
Mean 456
Standard deviation 5.8e+02
Values 1.3e+02 2.2e+02 4.8e+02 8.4 1.4e+03
[9]
HepG2 GSTA1
Mean 20.3
Standard deviation 5.9
Values 16 24
[10]
HepG2.C3A GSTA1
Mean 1.31
Standard deviation 0.69
Values 0.83 1.8
[11]
HuH.7 GSTA1
Mean 93.3
Standard deviation 39
Values 95 53 1.3e+02
[12]
SNU475 GSTA1
Mean 3.21
Standard deviation 3.3
Values 5.5 0.88
[13]
THLE GSTA1
Mean 0.127
Standard deviation 0.11
Values 0.21 0.048
[14]
liver GSTA1
Mean 52.8
Standard deviation 52
Values 29 48 1.3e+02 6.8
[15]
ref_hepatocyte GPX2
Mean 224
Standard deviation 2.7e+02
Values 61 9.6 5.9e+02 19 4.5e+02
[16]
HepG2 GPX2
Mean 274
Standard deviation 26
Values 2.9e+02 2.6e+02
[17]
HepG2.C3A GPX2
Mean 153
Standard deviation 85
Values 93 2.1e+02
[18]
HuH.7 GPX2
Mean 33.1
Standard deviation 7.7
Values 37 24 38
[19]
SNU475 GPX2
Mean 0.18
Standard deviation 0.025
Values 0.16 0.2
[20]
THLE GPX2
Mean 0.178
Standard deviation 0.026
Values 0.16 0.2
[21]
liver GPX2
Mean 218
Standard deviation 2.6e+02
Values 30 2.6e+02 5.7e+02 6.4
[22]
ref_hepatocyte GPX4
Mean 223
Standard deviation 63
Values 3.1e+02 1.4e+02 2e+02 2.2e+02 2.5e+02
[23]
HepG2 GPX4
Mean 141
Standard deviation 10
Values 1.5e+02 1.3e+02
[24]
HepG2.C3A GPX4
Mean 164
Standard deviation 3.3
Values 1.7e+02 1.6e+02
[25]
HuH.7 GPX4
Mean 128
Standard deviation 29
Values 1.1e+02 1.1e+02 1.6e+02
[26]
SNU475 GPX4
Mean 64.8
Standard deviation 11
Values 73 57
[27]
THLE GPX4
Mean 54.8
Standard deviation 1.7
Values 54 56
[28]
liver GPX4
Mean 91.2
Standard deviation 88
Values 18 1.7e+02 1.6e+02 12
[29]
ref_hepatocyte GSTA2
Mean 199
Standard deviation 3.4e+02
Values 27 48 1.2e+02 1.1 8e+02
[30]
HepG2 GSTA2
Mean 4.11
Standard deviation 1.5
Values 3.1 5.2
[31]
HepG2.C3A GSTA2
Mean 0.647
Standard deviation 0.13
Values 0.55 0.74
[32]
HuH.7 GSTA2
Mean 13.1
Standard deviation 7.6
Values 7.6 22 10
[33]
SNU475 GSTA2
Mean 0.525
Standard deviation 0.65
Values 0.98 0.066
[34]
THLE GSTA2
Mean 0.0506
Standard deviation 0.0038
Values 0.053 0.048
[35]
liver GSTA2
Mean 26.3
Standard deviation 39
Values 20 0.73 84 0.29
[36]
ref_hepatocyte GPX1
Mean 167
Standard deviation 1e+02
Values 30 1e+02 2.5e+02 2.7e+02 1.8e+02
[37]
HepG2 GPX1
Mean 128
Standard deviation 3.5
Values 1.3e+02 1.3e+02
[38]
HepG2.C3A GPX1
Mean 91.1
Standard deviation 33
Values 67 1.1e+02
[39]
HuH.7 GPX1
Mean 113
Standard deviation 55
Values 1.2e+02 55 1.6e+02
[40]
SNU475 GPX1
Mean 63.3
Standard deviation 6.4
Values 68 59
[41]
THLE GPX1
Mean 139
Standard deviation 16
Values 1.3e+02 1.5e+02
[42]
liver GPX1
Mean 81.8
Standard deviation 69
Values 25 1.4e+02 1.4e+02 19
[43]
ref_hepatocyte IDH2
Mean 157
Standard deviation 1.1e+02
Values 2e+02 52 2.6e+02 30 2.4e+02
[44]
HepG2 IDH2
Mean 85
Standard deviation 1.2
Values 86 84
[45]
HepG2.C3A IDH2
Mean 59.2
Standard deviation 12
Values 68 51
[46]
HuH.7 IDH2
Mean 77.5
Standard deviation 6.5
Values 83 70 79
[47]
SNU475 IDH2
Mean 40.8
Standard deviation 22
Values 56 26
[48]
THLE IDH2
Mean 18.2
Standard deviation 1.2
Values 17 19
[49]
liver IDH2
Mean 181
Standard deviation 68
Values 1.1e+02 2.1e+02 2.6e+02 1.4e+02
[50]
ref_hepatocyte GSTO1
Mean 150
Standard deviation 1e+02
Values 51 1.2e+02 2.1e+02 79 3e+02
[51]
HepG2 GSTO1
Mean 86.3
Standard deviation 4.3
Values 83 89
[52]
HepG2.C3A GSTO1
Mean 126
Standard deviation 39
Values 98 1.5e+02
[53]
HuH.7 GSTO1
Mean 84.1
Standard deviation 20
Values 84 65 1e+02
[54]
SNU475 GSTO1
Mean 15.2
Standard deviation 0.17
Values 15 15
[55]
THLE GSTO1
Mean 77.6
Standard deviation 17
Values 66 90
[56]
liver GSTO1
Mean 92.1
Standard deviation 75
Values 39 1.4e+02 1.7e+02 19
[57]
ref_hepatocyte IDH1
Mean 120
Standard deviation 80
Values 2.1e+02 57 1.2e+02 23 1.8e+02
[58]
HepG2 IDH1
Mean 186
Standard deviation 83
Values 1.3e+02 2.4e+02
[59]
HepG2.C3A IDH1
Mean 278
Standard deviation 72
Values 2.3e+02 3.3e+02
[60]
HuH.7 IDH1
Mean 559
Standard deviation 1.1e+02
Values 5.8e+02 4.4e+02 6.5e+02
[61]
SNU475 IDH1
Mean 74.8
Standard deviation 19
Values 88 61
[62]
THLE IDH1
Mean 42.2
Standard deviation 1.1
Values 43 41
[63]
liver IDH1
Mean 121
Standard deviation 35
Values 1.2e+02 1.4e+02 1.5e+02 74
[64]
ref_hepatocyte GSTK1
Mean 94
Standard deviation 81
Values 43 51 1.6e+02 16 2e+02
[65]
HepG2 GSTK1
Mean 25.5
Standard deviation 6
Values 21 30
[66]
HepG2.C3A GSTK1
Mean 33.8
Standard deviation 0.97
Values 34 33
[67]
HuH.7 GSTK1
Mean 38.4
Standard deviation 8.4
Values 40 30 46
[68]
SNU475 GSTK1
Mean 19.8
Standard deviation 7.5
Values 25 14
[69]
THLE GSTK1
Mean 14.9
Standard deviation 0.92
Values 16 14
[70]
liver GSTK1
Mean 65.4
Standard deviation 45
Values 28 1.1e+02 95 26
[71]
ref_hepatocyte PGD
Mean 93.2
Standard deviation 55
Values 91 1.7e+02 52 1.1e+02 34
[72]
HepG2 PGD
Mean 93.5
Standard deviation 3.9
Values 96 91
[73]
HepG2.C3A PGD
Mean 190
Standard deviation 27
Values 2.1e+02 1.7e+02
[74]
HuH.7 PGD
Mean 115
Standard deviation 2
Values 1.2e+02 1.2e+02 1.1e+02
[75]
SNU475 PGD
Mean 277
Standard deviation 55
Values 3.2e+02 2.4e+02
[76]
THLE PGD
Mean 37.6
Standard deviation 7.3
Values 32 43
[77]
liver PGD
Mean 40.9
Standard deviation 18
Values 34 38 67 25
[78]
ref_hepatocyte GPX3
Mean 87.9
Standard deviation 1.1e+02
Values 22 17 2.8e+02 47 76
[79]
HepG2 GPX3
Mean 240
Standard deviation 69
Values 2.9e+02 1.9e+02
[80]
HepG2.C3A GPX3
Mean 79.8
Standard deviation 13
Values 89 71
[81]
HuH.7 GPX3
Mean 74.5
Standard deviation 41
Values 51 1.2e+02 51
[82]
SNU475 GPX3
Mean 19.7
Standard deviation 2.7
Values 18 22
[83]
THLE GPX3
Mean 0.86
Standard deviation 0.062
Values 0.82 0.9
[84]
liver GPX3
Mean 265
Standard deviation 2.9e+02
Values 1.2e+02 2.3e+02 6.8e+02 35
[85]
ref_hepatocyte ODC1
Mean 80.4
Standard deviation 64
Values 34 1.7e+02 54 1.3e+02 20
[86]
HepG2 ODC1
Mean 152
Standard deviation 16
Values 1.4e+02 1.6e+02
[87]
HepG2.C3A ODC1
Mean 213
Standard deviation 1.3e+02
Values 1.2e+02 3e+02
[88]
HuH.7 ODC1
Mean 89.1
Standard deviation 41
Values 1e+02 42 1.2e+02
[89]
SNU475 ODC1
Mean 35.1
Standard deviation 2.2
Values 37 34
[90]
THLE ODC1
Mean 73.4
Standard deviation 18
Values 60 87
[91]
liver ODC1
Mean 29.6
Standard deviation 18
Values 50 10 39 20
[92]
ref_hepatocyte MGST2
Mean 73.6
Standard deviation 69
Values 20 29 1.2e+02 25 1.7e+02
[93]
HepG2 MGST2
Mean 38.6
Standard deviation 7.7
Values 33 44
[94]
HepG2.C3A MGST2
Mean 89.8
Standard deviation 3.2
Values 88 92
[95]
HuH.7 MGST2
Mean 26.6
Standard deviation 6.5
Values 24 22 34
[96]
SNU475 MGST2
Mean 8.62
Standard deviation 2.3
Values 10 7
[97]
THLE MGST2
Mean 9.5
Standard deviation 0.2
Values 9.4 9.6
[98]
liver MGST2
Mean 27.6
Standard deviation 24
Values 7.8 59 35 8.6
[99]
ref_hepatocyte ANPEP
Mean 59.7
Standard deviation 59
Values 13 14 1.2e+02 24 1.2e+02
[100]
HepG2 ANPEP
Mean 65.7
Standard deviation 12
Values 57 74
[101]
HepG2.C3A ANPEP
Mean 86.7
Standard deviation 36
Values 1.1e+02 61
[102]
HuH.7 ANPEP
Mean 11.1
Standard deviation 2.1
Values 11 13 9.3
[103]
SNU475 ANPEP
Mean 2.8
Standard deviation 2
Values 1.4 4.2
[104]
THLE ANPEP
Mean 19.6
Standard deviation 4.8
Values 16 23
[105]
liver ANPEP
Mean 137
Standard deviation 57
Values 72 1.9e+02 1.8e+02 1.1e+02
[106]
ref_hepatocyte GSTT1
Mean 52
Standard deviation 58
Values 17 5 86 14 1.4e+02
[107]
HepG2 GSTT1
Mean 28
Standard deviation 9.8
Values 21 35
[108]
HepG2.C3A GSTT1
Mean 28.3
Standard deviation 1.1
Values 28 29
[109]
HuH.7 GSTT1
Mean 0.0218
Standard deviation 0.015
Values 0.0082 0.039 0.019
[110]
SNU475 GSTT1
Mean 0.0116
Standard deviation 0.016
Values 0.023 0
[111]
THLE GSTT1
Mean 4.36
Standard deviation 0.38
Values 4.6 4.1
[112]
liver GSTT1
Mean 36.9
Standard deviation 41
Values 8.6 50 89 0
[113]
ref_hepatocyte SMS
Mean 48.6
Standard deviation 41
Values 35 1.1e+02 12 65 18
[114]
HepG2 SMS
Mean 60
Standard deviation 5.2
Values 64 56
[115]
HepG2.C3A SMS
Mean 45.7
Standard deviation 8.7
Values 40 52
[116]
HuH.7 SMS
Mean 54.1
Standard deviation 17
Values 59 35 69
[117]
SNU475 SMS
Mean 53.5
Standard deviation 0.37
Values 53 54
[118]
THLE SMS
Mean 60.3
Standard deviation 9.2
Values 54 67
[119]
liver SMS
Mean 11.4
Standard deviation 7.2
Values 6 16 19 4.4
[120]
ref_hepatocyte GSTZ1
Mean 46.1
Standard deviation 60
Values 4.8 6.8 66 9 1.4e+02
[121]
HepG2 GSTZ1
Mean 6.52
Standard deviation 0.28
Values 6.7 6.3
[122]
HepG2.C3A GSTZ1
Mean 9.98
Standard deviation 2.1
Values 11 8.5
[123]
HuH.7 GSTZ1
Mean 7.32
Standard deviation 1
Values 6.6 6.9 8.5
[124]
SNU475 GSTZ1
Mean 4.11
Standard deviation 1.9
Values 5.4 2.8
[125]
THLE GSTZ1
Mean 4.72
Standard deviation 0.55
Values 4.3 5.1
[126]
liver GSTZ1
Mean 18.6
Standard deviation 9.1
Values 7.5 28 16 23
[127]
ref_hepatocyte LAP3
Mean 37.6
Standard deviation 20
Values 26 26 46 20 70
[128]
HepG2 LAP3
Mean 48
Standard deviation 2.9
Values 46 50
[129]
HepG2.C3A LAP3
Mean 53.6
Standard deviation 1.3
Values 53 55
[130]
HuH.7 LAP3
Mean 51.1
Standard deviation 16
Values 58 33 62
[131]
SNU475 LAP3
Mean 27.2
Standard deviation 2.7
Values 29 25
[132]
THLE LAP3
Mean 24.5
Standard deviation 6.8
Values 20 29
[133]
liver LAP3
Mean 83.6
Standard deviation 24
Values 73 99 1.1e+02 55
[134]
ref_hepatocyte GSR
Mean 31.7
Standard deviation 20
Values 63 38 16 29 12
[135]
HepG2 GSR
Mean 101
Standard deviation 36
Values 1.3e+02 75
[136]
HepG2.C3A GSR
Mean 68.4
Standard deviation 11
Values 60 77
[137]
HuH.7 GSR
Mean 90.7
Standard deviation 6
Values 93 84 95
[138]
SNU475 GSR
Mean 101
Standard deviation 25
Values 1.2e+02 83
[139]
THLE GSR
Mean 37.8
Standard deviation 6.5
Values 33 42
[140]
liver GSR
Mean 24.8
Standard deviation 7.4
Values 30 16 21 32
[141]
ref_hepatocyte MGST3
Mean 29.9
Standard deviation 13
Values 15 35 48 20 33
[142]
HepG2 MGST3
Mean 14.5
Standard deviation 2.5
Values 13 16
[143]
HepG2.C3A MGST3
Mean 13.2
Standard deviation 1.3
Values 12 14
[144]
HuH.7 MGST3
Mean 21
Standard deviation 3.7
Values 19 19 25
[145]
SNU475 MGST3
Mean 30.6
Standard deviation 11
Values 38 23
[146]
THLE MGST3
Mean 33.4
Standard deviation 7.3
Values 28 39
[147]
liver MGST3
Mean 36.8
Standard deviation 33
Values 10 56 73 7.7
[148]
ref_hepatocyte SRM
Mean 28.1
Standard deviation 25
Values 6.5 15 33 70 16
[149]
HepG2 SRM
Mean 42.7
Standard deviation 0.29
Values 43 43
[150]
HepG2.C3A SRM
Mean 60.7
Standard deviation 5.5
Values 57 65
[151]
HuH.7 SRM
Mean 21.2
Standard deviation 10
Values 27 9.7 27
[152]
SNU475 SRM
Mean 25.5
Standard deviation 6.7
Values 21 30
[153]
THLE SRM
Mean 35.3
Standard deviation 5.7
Values 31 39
[154]
liver SRM
Mean 8.26
Standard deviation 6.7
Values 2.4 14 14 2.5
[155]
ref_hepatocyte GCLC
Mean 23.9
Standard deviation 11
Values 14 17 16 36 37
[156]
HepG2 GCLC
Mean 41.2
Standard deviation 0.21
Values 41 41
[157]
HepG2.C3A GCLC
Mean 47.1
Standard deviation 0.68
Values 48 47
[158]
HuH.7 GCLC
Mean 19.4
Standard deviation 7.4
Values 15 28 15
[159]
SNU475 GCLC
Mean 84.8
Standard deviation 9.1
Values 91 78
[160]
THLE GCLC
Mean 14.4
Standard deviation 0.55
Values 15 14
[161]
liver GCLC
Mean 45.3
Standard deviation 20
Values 59 37 22 64
[162]
ref_hepatocyte GGCT
Mean 22.9
Standard deviation 5.2
Values 29 25 18 25 17
[163]
HepG2 GGCT
Mean 13.1
Standard deviation 2.8
Values 11 15
[164]
HepG2.C3A GGCT
Mean 19.9
Standard deviation 7.3
Values 15 25
[165]
HuH.7 GGCT
Mean 40
Standard deviation 16
Values 42 23 55
[166]
SNU475 GGCT
Mean 15.4
Standard deviation 3.1
Values 13 18
[167]
THLE GGCT
Mean 17.5
Standard deviation 1.8
Values 16 19
[168]
liver GGCT
Mean 7.28
Standard deviation 5.4
Values 3.4 11 13 1.9
[169]
ref_hepatocyte GCLM
Mean 20.7
Standard deviation 17
Values 12 45 8.4 32 5.2
[170]
HepG2 GCLM
Mean 23.3
Standard deviation 15
Values 34 13
[171]
HepG2.C3A GCLM
Mean 12.1
Standard deviation 3.1
Values 9.9 14
[172]
HuH.7 GCLM
Mean 16.1
Standard deviation 2.7
Values 16 19 13
[173]
SNU475 GCLM
Mean 68.3
Standard deviation 0.053
Values 68 68
[174]
THLE GCLM
Mean 21.6
Standard deviation 2.7
Values 20 24
[175]
liver GCLM
Mean 16.4
Standard deviation 8.1
Values 14 18 27 7
[176]
ref_hepatocyte GSS
Mean 17.2
Standard deviation 2.6
Values 14 16 20 20 17
[177]
HepG2 GSS
Mean 61.8
Standard deviation 7.1
Values 57 67
[178]
HepG2.C3A GSS
Mean 45
Standard deviation 7.3
Values 40 50
[179]
HuH.7 GSS
Mean 27.4
Standard deviation 7
Values 27 20 34
[180]
SNU475 GSS
Mean 39.8
Standard deviation 5.9
Values 44 36
[181]
THLE GSS
Mean 29.3
Standard deviation 2.5
Values 27 31
[182]
liver GSS
Mean 20.8
Standard deviation 9.9
Values 14 26 32 11
[183]
ref_hepatocyte TXNDC12
Mean 16
Standard deviation 6.3
Values 15 8.9 25 12 19
[184]
HepG2 TXNDC12
Mean 61.1
Standard deviation 4.9
Values 58 65
[185]
HepG2.C3A TXNDC12
Mean 75.6
Standard deviation 12
Values 67 84
[186]
HuH.7 TXNDC12
Mean 44.5
Standard deviation 9.2
Values 44 36 54
[187]
SNU475 TXNDC12
Mean 16.9
Standard deviation 1.2
Values 16 18
[188]
THLE TXNDC12
Mean 39.5
Standard deviation 3.6
Values 37 42
[189]
liver TXNDC12
Mean 21.7
Standard deviation 14
Values 13 36 31 7.4
[190]
ref_hepatocyte GGT1
Mean 15.1
Standard deviation 12
Values 0.7 20 29 4.1 22
[191]
HepG2 GGT1
Mean 20.9
Standard deviation 6.9
Values 26 16
[192]
HepG2.C3A GGT1
Mean 15.5
Standard deviation 4.3
Values 19 12
[193]
HuH.7 GGT1
Mean 12.7
Standard deviation 3.6
Values 11 17 9.9
[194]
SNU475 GGT1
Mean 6.1
Standard deviation 1.7
Values 7.3 4.9
[195]
THLE GGT1
Mean 0.294
Standard deviation 0.0057
Values 0.29 0.3
[196]
liver GGT1
Mean 35.2
Standard deviation 23
Values 15 65 40 21
[197]
ref_hepatocyte GSTA4
Mean 11.5
Standard deviation 10
Values 29 9.2 8 0.55 11
[198]
HepG2 GSTA4
Mean 11.2
Standard deviation 1.3
Values 10 12
[199]
HepG2.C3A GSTA4
Mean 12.1
Standard deviation 1.1
Values 11 13
[200]
HuH.7 GSTA4
Mean 26.2
Standard deviation 3.6
Values 25 24 30
[201]
SNU475 GSTA4
Mean 22.2
Standard deviation 8.7
Values 28 16
[202]
THLE GSTA4
Mean 6.87
Standard deviation 0.55
Values 6.5 7.3
[203]
liver GSTA4
Mean 5.88
Standard deviation 4
Values 2.3 11 7.6 2.9
[204]
ref_hepatocyte RRM2
Mean 11.3
Standard deviation 12
Values 21 27 4.7 0.89 2.6
[205]
HepG2 RRM2
Mean 74.3
Standard deviation 40
Values 46 1e+02
[206]
HepG2.C3A RRM2
Mean 72.7
Standard deviation 62
Values 29 1.2e+02
[207]
HuH.7 RRM2
Mean 49
Standard deviation 32
Values 67 12 68
[208]
SNU475 RRM2
Mean 89.3
Standard deviation 5.3
Values 86 93
[209]
THLE RRM2
Mean 103
Standard deviation 25
Values 85 1.2e+02
[210]
liver RRM2
Mean 8.94
Standard deviation 9.7
Values 9.4 3.1 22 0.81
[211]
ref_hepatocyte GSTM4
Mean 9.44
Standard deviation 5.5
Values 11 5.2 14 2.4 15
[212]
HepG2 GSTM4
Mean 11.9
Standard deviation 5
Values 8.4 15
[213]
HepG2.C3A GSTM4
Mean 7.23
Standard deviation 1
Values 8 6.5
[214]
HuH.7 GSTM4
Mean 7.9
Standard deviation 0.7
Values 8.4 7.1 8.2
[215]
SNU475 GSTM4
Mean 14.8
Standard deviation 7.9
Values 20 9.2
[216]
THLE GSTM4
Mean 1.82
Standard deviation 0.44
Values 2.1 1.5
[217]
liver GSTM4
Mean 11.3
Standard deviation 5.6
Values 5.7 18 14 7.7
[218]
ref_hepatocyte RRM1
Mean 8.31
Standard deviation 6.1
Values 11 18 5 3.3 4.7
[219]
HepG2 RRM1
Mean 51
Standard deviation 21
Values 37 66
[220]
HepG2.C3A RRM1
Mean 32.9
Standard deviation 21
Values 18 47
[221]
HuH.7 RRM1
Mean 51
Standard deviation 15
Values 59 34 61
[222]
SNU475 RRM1
Mean 63.2
Standard deviation 3.6
Values 61 66
[223]
THLE RRM1
Mean 76.5
Standard deviation 23
Values 60 93
[224]
liver RRM1
Mean 12.6
Standard deviation 3.4
Values 15 9.3 16 10
[225]
ref_hepatocyte G6PD
Mean 7
Standard deviation 9.9
Values 24 7.7 1.1 1.2 1.1
[226]
HepG2 G6PD
Mean 99.6
Standard deviation 38
Values 1.3e+02 73
[227]
HepG2.C3A G6PD
Mean 22.6
Standard deviation 2
Values 24 21
[228]
HuH.7 G6PD
Mean 18.1
Standard deviation 6.7
Values 24 11 19
[229]
SNU475 G6PD
Mean 293
Standard deviation 1.9e+02
Values 4.3e+02 1.6e+02
[230]
THLE G6PD
Mean 39.9
Standard deviation 6.1
Values 36 44
[231]
liver G6PD
Mean 1.72
Standard deviation 0.72
Values 1 1.6 2.7 1.6
[232]
ref_hepatocyte GSTP1
Mean 6.16
Standard deviation 5.2
Values 0 2.2 6 13 9.9
[233]
HepG2 GSTP1
Mean 0.872
Standard deviation 0.24
Values 0.7 1
[234]
HepG2.C3A GSTP1
Mean 1.43
Standard deviation 0.0018
Values 1.4 1.4
[235]
HuH.7 GSTP1
Mean 283
Standard deviation 1e+02
Values 2.9e+02 1.8e+02 3.8e+02
[236]
SNU475 GSTP1
Mean 592
Standard deviation 1.2e+02
Values 6.7e+02 5.1e+02
[237]
THLE GSTP1
Mean 140
Standard deviation 16
Values 1.3e+02 1.5e+02
[238]
liver GSTP1
Mean 8.38
Standard deviation 7.4
Values 2 17 12 2.6
[239]
ref_hepatocyte RRM2B
Mean 5.12
Standard deviation 4.1
Values 7.3 11 1.6 2.8 2.6
[240]
HepG2 RRM2B
Mean 26.7
Standard deviation 1.8
Values 25 28
[241]
HepG2.C3A RRM2B
Mean 26.7
Standard deviation 5.2
Values 23 30
[242]
HuH.7 RRM2B
Mean 11.3
Standard deviation 1.7
Values 12 13 9.5
[243]
SNU475 RRM2B
Mean 18.9
Standard deviation 5.1
Values 23 15
[244]
THLE RRM2B
Mean 18.4
Standard deviation 0.84
Values 19 18
[245]
liver RRM2B
Mean 9.96
Standard deviation 2.3
Values 12 7.4 12 8.6
[246]
ref_hepatocyte OPLAH
Mean 4.64
Standard deviation 4.4
Values 2.4 0.7 7.2 1.9 11
[247]
HepG2 OPLAH
Mean 19.7
Standard deviation 2.6
Values 22 18
[248]
HepG2.C3A OPLAH
Mean 18.1
Standard deviation 9.1
Values 25 12
[249]
HuH.7 OPLAH
Mean 6.03
Standard deviation 0.25
Values 6.2 5.7 6.2
[250]
SNU475 OPLAH
Mean 6.37
Standard deviation 3.8
Values 9.1 3.7
[251]
THLE OPLAH
Mean 1.73
Standard deviation 0.08
Values 1.7 1.8
[252]
liver OPLAH
Mean 21
Standard deviation 13
Values 19 14 10 40
[253]
ref_hepatocyte GSTT2
Mean 3.22
Standard deviation 3.2
Values 0 1.1 7.8 2.2 5.1
[254]
HepG2 GSTT2
Mean 0.0444
Standard deviation 0.022
Values 0.029 0.06
[255]
HepG2.C3A GSTT2
Mean 0.0102
Standard deviation 0.00071
Values 0.0097 0.011
[256]
HuH.7 GSTT2
Mean 0.00547
Standard deviation 0.0095
Values 0.016 0 0
[257]
SNU475 GSTT2
Mean 0.19
Standard deviation 0.13
Values 0.28 0.1
[258]
THLE GSTT2
Mean 0.671
Standard deviation 0.33
Values 0.44 0.9
[259]
liver GSTT2
Mean 0.384
Standard deviation 0.24
Values 0.16 0.73 0.36 0.29
[260]
ref_hepatocyte GSTM3
Mean 2.88
Standard deviation 2.5
Values 6.2 4.8 1.6 0.21 1.6
[261]
HepG2 GSTM3
Mean 32.9
Standard deviation 4.6
Values 30 36
[262]
HepG2.C3A GSTM3
Mean 18.6
Standard deviation 2.4
Values 17 20
[263]
HuH.7 GSTM3
Mean 3.57
Standard deviation 0.4
Values 3.4 3.3 4
[264]
SNU475 GSTM3
Mean 38.7
Standard deviation 3.4
Values 41 36
[265]
THLE GSTM3
Mean 38.5
Standard deviation 4.1
Values 41 36
[266]
liver GSTM3
Mean 11.7
Standard deviation 7.4
Values 4.8 22 13 7.3
[267]
ref_hepatocyte GPX7
Mean 1.92
Standard deviation 3
Values 7.2 0.19 0.82 0.82 0.54
[268]
HepG2 GPX7
Mean 3.18
Standard deviation 0.14
Values 3.3 3.1
[269]
HepG2.C3A GPX7
Mean 5.13
Standard deviation 0.33
Values 5.4 4.9
[270]
HuH.7 GPX7
Mean 4.54
Standard deviation 0.85
Values 3.7 4.5 5.4
[271]
SNU475 GPX7
Mean 0.278
Standard deviation 0.25
Values 0.45 0.1
[272]
THLE GPX7
Mean 1.43
Standard deviation 0.15
Values 1.5 1.3
[273]
liver GPX7
Mean 1.97
Standard deviation 0.54
Values 1.9 2.1 2.6 1.3
[274]
ref_hepatocyte GGT7
Mean 1.61
Standard deviation 1.1
Values 1.5 0.71 2.8 0.35 2.6
[275]
HepG2 GGT7
Mean 12.2
Standard deviation 0.96
Values 13 12
[276]
HepG2.C3A GGT7
Mean 13.6
Standard deviation 5.5
Values 18 9.8
[277]
HuH.7 GGT7
Mean 9.57
Standard deviation 2.2
Values 7.5 12 9.5
[278]
SNU475 GGT7
Mean 11.5
Standard deviation 1.7
Values 13 10
[279]
THLE GGT7
Mean 7.01
Standard deviation 1.9
Values 8.3 5.7
[280]
liver GGT7
Mean 2.93
Standard deviation 1
Values 4.2 2.2 2.1 3.3
[281]
ref_hepatocyte GSTO2
Mean 1.37
Standard deviation 1.2
Values 0.43 0.34 3.3 0.98 1.8
[282]
HepG2 GSTO2
Mean 1.28
Standard deviation 0.51
Values 1.6 0.92
[283]
HepG2.C3A GSTO2
Mean 7.24
Standard deviation 0.65
Values 7.7 6.8
[284]
HuH.7 GSTO2
Mean 1.29
Standard deviation 0.42
Values 1.1 0.96 1.8
[285]
SNU475 GSTO2
Mean 0.0882
Standard deviation 0.033
Values 0.065 0.11
[286]
THLE GSTO2
Mean 0.444
Standard deviation 0.026
Values 0.43 0.46
[287]
liver GSTO2
Mean 0.821
Standard deviation 0.41
Values 0.81 0.63 1.4 0.45
[288]
ref_hepatocyte GSTM2
Mean 0.961
Standard deviation 0.9
Values 1.9 0 1.3 0 1.7
[289]
HepG2 GSTM2
Mean 2.78
Standard deviation 0.68
Values 2.3 3.3
[290]
HepG2.C3A GSTM2
Mean 1.04
Standard deviation 0.29
Values 1.2 0.84
[291]
HuH.7 GSTM2
Mean 3.46
Standard deviation 0.18
Values 3.4 3.3 3.7
[292]
SNU475 GSTM2
Mean 4.89
Standard deviation 2.9
Values 7 2.8
[293]
THLE GSTM2
Mean 3.5
Standard deviation 0.29
Values 3.7 3.3
[294]
liver GSTM2
Mean 1.38
Standard deviation 0.62
Values 0.53 1.9 1.8 1.3
[295]
ref_hepatocyte GSTM1
Mean 0.404
Standard deviation 0.25
Values 0.52 0.62 0.52 0 0.36
[296]
HepG2 GSTM1
Mean 0.18
Standard deviation 0.14
Values 0.08 0.28
[297]
HepG2.C3A GSTM1
Mean 0.0657
Standard deviation 0.017
Values 0.078 0.054
[298]
HuH.7 GSTM1
Mean 4.5
Standard deviation 1.1
Values 5.5 3.3 4.7
[299]
SNU475 GSTM1
Mean 12.6
Standard deviation 6.3
Values 17 8.2
[300]
THLE GSTM1
Mean 0.0417
Standard deviation 0.0088
Values 0.035 0.048
[301]
liver GSTM1
Mean 54
Standard deviation 35
Values 15 93 70 38
[302]
ref_hepatocyte GGT6
Mean 0.301
Standard deviation 0.36
Values 0.92 0.06 0.06 0.2 0.28
[303]
HepG2 GGT6
Mean 0.834
Standard deviation 0.027
Values 0.85 0.82
[304]
HepG2.C3A GGT6
Mean 1.08
Standard deviation 0.082
Values 1 1.1
[305]
HuH.7 GGT6
Mean 0.31
Standard deviation 0.14
Values 0.24 0.47 0.22
[306]
SNU475 GGT6
Mean 0.28
Standard deviation 0.044
Values 0.31 0.25
[307]
THLE GGT6
Mean 0.19
Standard deviation 0.077
Values 0.14 0.24
[308]
liver GGT6
Mean 0.426
Standard deviation 0.13
Values 0.3 0.61 0.41 0.38
[309]
ref_hepatocyte GGT5
Mean 0.17
Standard deviation 0.18
Values 0.15 0 0.41 0 0.3
[310]
HepG2 GGT5
Mean 8.97
Standard deviation 6.7
Values 14 4.3
[311]
HepG2.C3A GGT5
Mean 1.3
Standard deviation 0.47
Values 0.97 1.6
[312]
HuH.7 GGT5
Mean 0.0424
Standard deviation 0.034
Values 0.074 0.0064 0.047
[313]
SNU475 GGT5
Mean 4.71
Standard deviation 2.8
Values 2.7 6.7
[314]
THLE GGT5
Mean 5.79
Standard deviation 1.9
Values 4.5 7.1
[315]
liver GGT5
Mean 12
Standard deviation 7.3
Values 4.2 13 21 9.1
[316]
ref_hepatocyte GSTA5
Mean 0.13
Standard deviation 0.18
Values 0 0.32 0 0 0.33
[317]
HepG2 GSTA5
Mean 0.00214
Standard deviation 0.003
Values 0 0.0043
[318]
HepG2.C3A GSTA5
Mean 0
Standard deviation 0
Values 0 0
[319]
HuH.7 GSTA5
Mean 0.00273
Standard deviation 0.0047
Values 0.0082 0 0
[320]
SNU475 GSTA5
Mean 0
Standard deviation 0
Values 0 0
[321]
THLE GSTA5
Mean 0
Standard deviation 0
Values 0 0
[322]
liver GSTA5
Mean 0
Standard deviation 0
Values 0 0 0 0
[323]
ref_hepatocyte GSTA3
Mean 0.0781
Standard deviation 0.11
Values 0 0 0.15 0 0.24
[324]
HepG2 GSTA3
Mean 0.00214
Standard deviation 0.003
Values 0 0.0043
[325]
HepG2.C3A GSTA3
Mean 0
Standard deviation 0
Values 0 0
[326]
HuH.7 GSTA3
Mean 0.0121
Standard deviation 0.014
Values 0.0082 0 0.028
[327]
SNU475 GSTA3
Mean 0.0359
Standard deviation 0.015
Values 0.046 0.025
[328]
THLE GSTA3
Mean 0
Standard deviation 0
Values 0 0
[329]
liver GSTA3
Mean 0
Standard deviation 0
Values 0 0 0 0
[330]
ref_hepatocyte GPX6
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[331]
HepG2 GPX6
Mean 0
Standard deviation 0
Values 0 0
[332]
HepG2.C3A GPX6
Mean 0
Standard deviation 0
Values 0 0
[333]
HuH.7 GPX6
Mean 0
Standard deviation 0
Values 0 0 0
[334]
SNU475 GPX6
Mean 0
Standard deviation 0
Values 0 0
[335]
THLE GPX6
Mean 0
Standard deviation 0
Values 0 0
[336]
liver GPX6
Mean 0.00357
Standard deviation 0.0071
Values 0.014 0 0 0
[337]
ref_hepatocyte GPX5
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[338]
HepG2 GPX5
Mean 0
Standard deviation 0
Values 0 0
[339]
HepG2.C3A GPX5
Mean 0
Standard deviation 0
Values 0 0
[340]
HuH.7 GPX5
Mean 0
Standard deviation 0
Values 0 0 0
[341]
SNU475 GPX5
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[342]
THLE GPX5
Mean 0
Standard deviation 0
Values 0 0
[343]
liver GPX5
Mean 0.00642
Standard deviation 0.013
Values 0 0 0.026 0
[344]
ref_hepatocyte GSTM5
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[345]
HepG2 GSTM5
Mean 0.00429
Standard deviation 0.0061
Values 0 0.0086
[346]
HepG2.C3A GSTM5
Mean 0
Standard deviation 0
Values 0 0
[347]
HuH.7 GSTM5
Mean 0.00273
Standard deviation 0.0047
Values 0.0082 0 0
[348]
SNU475 GSTM5
Mean 0.0127
Standard deviation 0.018
Values 0 0.025
[349]
THLE GSTM5
Mean 0
Standard deviation 0
Values 0 0
[350]
liver GSTM5
Mean 0.506
Standard deviation 0.46
Values 0.16 1.1 0.62 0.15