KEGG_GLIOMA | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | CALM2 | Calmodulin-2 | [1] | -1.87[2] | -1.03[3] | -2.42[4] | -1.98[5] | -1.67[6] | -1.83[7] |
2 | CALM3 | Calmodulin-3 | [8] | -0.42[9] | -0.71[10] | 0.57[11] | -0.56[12] | -0.70[13] | -2.23[14] |
3 | CDKN1A | Cyclin-dependent kinase inhibitor 1 | [15] | 0.48[16] | -0.94[17] | -3.55[18] | -2.21[19] | 0.35[20] | -1.94[21] |
4 | AKT1 | RAC-alpha serine/threonine-protein kinase | [22] | -0.28[23] | -0.54[24] | -1.54[25] | -0.28[26] | -0.24[27] | -0.35[28] |
5 | CALM1 | Calmodulin-1 | [29] | -0.28[30] | -0.27[31] | 0.27[32] | 1.36[33] | 0.64[34] | 1.51[35] |
6 | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 | [36] | -1.28[37] | -1.64[38] | -0.98[39] | -0.77[40] | -0.25[41] | -1.30[42] |
7 | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2 | [43] | -0.30[44] | -0.65[45] | 0.30[46] | -1.07[47] | -0.57[48] | -1.81[49] |
8 | CCND1 | G1/S-specific cyclin-D1 | [50] | 2.70[51] | 0.16[52] | 1.07[53] | 1.65[54] | 0.19[55] | 0.95[56] |
9 | GRB2 | Growth factor receptor-bound protein 2 | [57] | 0.84[58] | 0.65[59] | 0.85[60] | 0.33[61] | 0.25[62] | 0.19[63] |
10 | CDK4 | Cyclin-dependent kinase 4 | [64] | 0.98[65] | 1.53[66] | 1.24[67] | -0.05[68] | 0.61[69] | -0.94[70] |
11 | IGF1 | Insulin-like growth factor I | [71] | -8.78[72] | -9.74[73] | -7.88[74] | -1.77[75] | -9.59[76] | 0.81[77] |
12 | SHC1 | SHC-transforming protein 1 | [78] | 0.81[79] | 1.00[80] | 1.15[81] | 2.42[82] | 1.92[83] | 0.67[84] |
13 | RAF1 | RAF proto-oncogene serine/threonine-protein kinase | [85] | -0.42[86] | -0.04[87] | 1.30[88] | -0.41[89] | 0.46[90] | 0.99[91] |
14 | NRAS | GTPase NRas | [92] | 0.27[93] | 0.68[94] | 1.17[95] | 0.77[96] | 0.35[97] | -0.36[98] |
15 | ARAF | Serine/threonine-protein kinase A-Raf | [99] | -0.81[100] | -1.15[101] | -0.80[102] | -0.32[103] | -0.28[104] | 0.77[105] |
16 | HRAS | GTPase HRas | [106] | -1.36[107] | -2.10[108] | -2.81[109] | -1.17[110] | -1.38[111] | -2.77[112] |
17 | MAPK1 | Mitogen-activated protein kinase 1 | [113] | 1.35[114] | 1.46[115] | 1.37[116] | 1.62[117] | 1.28[118] | 1.67[119] |
18 | AKT2 | RAC-beta serine/threonine-protein kinase | [120] | 0.60[121] | 0.85[122] | 1.06[123] | 0.63[124] | 0.43[125] | 1.02[126] |
19 | SHC2 | SHC-transforming protein 2 | [127] | -1.74[128] | -1.41[129] | -2.18[130] | -4.89[131] | -4.51[132] | -0.48[133] |
20 | KRAS | GTPase KRas | [134] | -0.87[135] | -0.92[136] | 0.76[137] | 0.58[138] | 0.24[139] | 0.57[140] |
21 | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha | [141] | -0.83[142] | -0.74[143] | 0.43[144] | 1.84[145] | 1.35[146] | 2.89[147] |
22 | SOS1 | Son of sevenless homolog 1 | [148] | -0.46[149] | 1.04[150] | 0.63[151] | 0.62[152] | -0.14[153] | 0.43[154] |
23 | PTEN | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protei | -0.89[155] | 0.47[156] | 0.75[157] | -0.79[158] | 0.47[159] | 2.37[160] | |
24 | MDM2 | E3 ubiquitin-protein ligase Mdm2 | [161] | 1.75[162] | 3.14[163] | 0.46[164] | 0.28[165] | 1.17[166] | 2.06[167] |
25 | CAMK2D | Calcium/calmodulin-dependent protein kinase type II subunit delta | [168] | -0.22[169] | 0.05[170] | 1.66[171] | 0.45[172] | -0.35[173] | 1.30[174] |
26 | EGFR | Epidermal growth factor receptor | [175] | -1.05[176] | -1.46[177] | 1.50[178] | 0.21[179] | 0.84[180] | 2.54[181] |
27 | TP53 | Cellular tumor antigen p53 | [182] | 1.28[183] | 0.81[184] | 1.65[185] | 1.07[186] | 0.74[187] | -0.15[188] |
28 | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta | [189] | 1.52[190] | 1.71[191] | 2.40[192] | 0.48[193] | 1.05[194] | -0.40[195] |
29 | MAPK3 | Mitogen-activated protein kinase 3 | [196] | 1.49[197] | 1.51[198] | 1.63[199] | 0.20[200] | 0.23[201] | -1.15[202] |
30 | CDK6 | Cyclin-dependent kinase 6 | [203] | 1.69[204] | 2.36[205] | 0.84[206] | 0.69[207] | 1.50[208] | 1.96[209] |
31 | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | 3.13[210] | 2.72[211] | 2.13[212] | 2.60[213] | 2.10[214] | 0.23[215] | |
32 | MTOR | Serine/threonine-protein kinase mTOR | [216] | 2.18[217] | 3.16[218] | 2.81[219] | 2.46[220] | 2.55[221] | 3.34[222] |
33 | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 0.86[223] | 1.33[224] | 1.57[225] | 0.82[226] | 0.99[227] | 1.05[228] | |
34 | RB1 | Retinoblastoma-associated protein | [229] | 0.86[230] | 1.33[231] | 1.97[232] | 2.05[233] | 2.39[234] | 1.37[235] |
35 | CAMK2G | Calcium/calmodulin-dependent protein kinase type II subunit gamma | 0.42[236] | 1.60[237] | 1.29[238] | 1.46[239] | 1.03[240] | 0.85[241] | |
36 | SOS2 | Son of sevenless homolog 2 | [242] | -0.38[243] | 0.71[244] | 0.02[245] | 1.46[246] | 1.34[247] | 1.73[248] |
37 | E2F1 | Transcription factor E2F1 | [249] | 1.59[250] | 1.42[251] | 1.62[252] | 1.64[253] | 2.09[254] | -3.72[255] |
38 | PRKCA | Protein kinase C alpha type | [256] | 2.48[257] | 2.49[258] | 2.93[259] | 1.92[260] | 2.29[261] | 1.81[262] |
39 | E2F3 | Transcription factor E2F3 | [263] | 1.36[264] | 1.16[265] | 0.49[266] | 2.40[267] | 1.86[268] | -0.28[269] |
40 | TGFA | Protransforming growth factor alpha | [270] | 1.44[271] | 2.47[272] | -8.50[273] | -1.19[274] | -2.40[275] | -0.50[276] |
41 | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | -0.74[277] | 0.87[278] | 1.14[279] | 0.90[280] | 1.12[281] | 1.81[282] | |
42 | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 1.53[283] | 2.59[284] | -1.14[285] | 0.05[286] | 0.83[287] | 0.19[288] | |
43 | PDGFA | Platelet-derived growth factor subunit A | [289] | -1.36[290] | -1.18[291] | 0.99[292] | -0.57[293] | -1.47[294] | -0.86[295] |
44 | BRAF | Serine/threonine-protein kinase B-raf | [296] | -0.11[297] | -0.41[298] | 1.70[299] | 0.51[300] | 0.22[301] | 1.74[302] |
45 | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | -1.64[303] | -7.41[304] | 0.11[305] | -2.96[306] | -1.80[307] | 2.61[308] | |
46 | IGF1R | Insulin-like growth factor 1 receptor | [309] | 4.39[310] | 3.67[311] | 2.42[312] | 4.24[313] | 3.80[314] | 1.98[315] |
47 | PDGFB | Platelet-derived growth factor subunit B | [316] | 2.70[317] | 2.53[318] | -0.20[319] | -0.16[320] | -0.58[321] | 0.26[322] |
48 | CAMK2B | Calcium/calmodulin-dependent protein kinase type II subunit beta | [323] | -2.89[324] | -4.24[325] | -7.13[326] | -3.09[327] | -2.44[328] | 1.04[329] |
49 | PDGFRA | Platelet-derived growth factor receptor alpha | [330] | -3.98[331] | -4.98[332] | 2.73[333] | 0.30[334] | 4.98[335] | 5.21[336] |
50 | PDGFRB | Platelet-derived growth factor receptor beta | [337] | 0.94[338] | 1.31[339] | -1.06[340] | 1.63[341] | 2.20[342] | 3.31[343] |
51 | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma | [344] | 1.37[345] | 1.35[346] | 2.27[347] | 2.94[348] | 1.97[349] | 2.57[350] |
52 | AKT3 | RAC-gamma serine/threonine-protein kinase | [351] | -2.20[352] | -4.79[353] | -4.02[354] | 5.62[355] | 4.58[356] | 3.50[357] |
53 | PIK3R5 | Phosphoinositide 3-kinase regulatory subunit 5 | [358] | -7.52[359] | [360] | -2.84[361] | -4.15[362] | -3.80[363] | 2.23[364] |
54 | CDKN2A | Cyclin-dependent kinase inhibitor 2A | [365] | 3.73[366] | 1.46[367] | 4.95[368] | 4.98[369] | 6.78[370] | -2.26[371] |
55 | PRKCB | Protein kinase C beta type | [372] | -7.17[373] | -6.00[374] | [375] | 2.26[376] | -3.04[377] | 3.43[378] |
56 | E2F2 | Transcription factor E2F2 | [379] | 3.89[380] | 4.75[381] | 4.35[382] | 3.83[383] | 4.16[384] | 1.31[385] |
57 | CALML3 | Calmodulin-like protein 3 | [386] | -2.96[387] | -2.82[388] | -5.28[389] | [390] | -3.39[391] | -2.45[392] |
58 | PIK3CG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | [393] | [394] | [395] | 1.11[396] | -3.76[397] | 3.99[398] | |
59 | SHC4 | SHC-transforming protein 4 | [399] | -2.62[400] | [401] | -2.01[402] | 2.30[403] | 2.69[404] | -0.80[405] |
60 | SHC3 | SHC-transforming protein 3 | [406] | 1.75[407] | 4.10[408] | -3.31[409] | 3.23[410] | 7.15[411] | 1.71[412] |
61 | PRKCG | Protein kinase C gamma type | [413] | -1.18[414] | -0.53[415] | -2.83[416] | -1.29[417] | -1.37[418] | [419] |
62 | EGF | Pro-epidermal growth factor | [420] | 1.61[421] | 3.37[422] | 7.06[423] | 8.80[424] | 6.23[425] | 1.47[426] |
63 | CALML5 | Calmodulin-like protein 5 | [427] | [428] | [429] | [430] | [431] | [432] | [433] |
64 | CALML6 | Calmodulin-like protein 6 | [434] | [435] | [436] | [437] | [438] | [439] | [440] |
65 | CAMK2A | Calcium/calmodulin-dependent protein kinase type II subunit alpha | [441] | [442] | [443] | [444] | [445] | [446] | [447] |