KEGG_GAP_JUNCTION |
Return to index |
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Order |
Gene |
Description |
ref_hepatocyte |
HepG2 |
HepG2.C3A |
HuH.7 |
SNU475 |
THLE |
liver |
1 |
TUBA1B |
Tubulin alpha-1B chain |
[1] |
-1.10[2] |
-0.87[3] |
-0.71[4] |
-1.21[5] |
-0.48[6] |
-1.91[7] |
2 |
TUBA1C |
Tubulin alpha-1C chain |
[8] |
-1.72[9] |
-1.57[10] |
-2.15[11] |
-1.87[12] |
-2.08[13] |
-3.13[14] |
3 |
TUBB4B |
Tubulin beta-4B chain |
[15] |
-1.05[16] |
-0.93[17] |
-1.03[18] |
-1.90[19] |
-0.84[20] |
-0.82[21] |
4 |
TUBB |
Tubulin beta chain |
[22] |
1.52[23] |
1.01[24] |
1.33[25] |
1.31[26] |
0.79[27] |
-0.13[28] |
5 |
GNAS |
Guanine nucleotide-binding protein
G(s) subunit alpha isoforms XLas |
0.17[29] |
0.42[30] |
0.00[31] |
0.59[32] |
-0.01[33] |
-0.69[34] |
6 |
TUBA4A |
Tubulin alpha-4A chain |
[35] |
-4.31[36] |
-4.26[37] |
-5.10[38] |
-2.06[39] |
-2.06[40] |
-1.97[41] |
7 |
TUBB2A |
Tubulin beta-2A chain |
[42] |
-3.49[43] |
-3.37[44] |
-2.18[45] |
-2.39[46] |
-4.49[47] |
-2.13[48] |
8 |
GNAI2 |
Guanine nucleotide-binding protein G(i) subunit alpha-2 |
[49] |
-0.20[50] |
-1.04[51] |
-0.95[52] |
-0.43[53] |
0.81[54] |
0.45[55] |
9 |
MAP2K1 |
Dual specificity mitogen-activated protein kinase kinase 1 |
[56] |
-1.19[57] |
-1.30[58] |
-0.80[59] |
-0.80[60] |
-0.13[61] |
-0.55[62] |
10 |
MAP2K2 |
Dual specificity mitogen-activated protein kinase kinase 2 |
[63] |
-0.21[64] |
-0.31[65] |
0.48[66] |
-1.10[67] |
-0.45[68] |
-1.06[69] |
11 |
GRB2 |
Growth factor receptor-bound protein 2 |
[70] |
0.93[71] |
0.99[72] |
1.04[73] |
0.30[74] |
0.38[75] |
0.94[76] |
12 |
CSNK1D |
Casein kinase I isoform delta |
[77] |
0.91[78] |
0.90[79] |
0.73[80] |
0.77[81] |
0.47[82] |
0.05[83] |
13 |
PRKACA |
cAMP-dependent protein kinase catalytic subunit alpha |
[84] |
-0.43[85] |
-0.38[86] |
-0.46[87] |
-0.73[88] |
0.03[89] |
-0.14[90] |
14 |
GNAI3 |
Guanine nucleotide-binding protein G(k) subunit alpha |
[91] |
-0.14[92] |
0.63[93] |
0.65[94] |
0.85[95] |
0.64[96] |
0.88[97] |
15 |
RAF1 |
RAF proto-oncogene serine/threonine-protein kinase |
[98] |
-0.32[99] |
0.30[100] |
1.49[101] |
-0.44[102] |
0.59[103] |
1.74[104] |
16 |
NRAS |
GTPase NRas |
[105] |
0.37[106] |
1.02[107] |
1.36[108] |
0.74[109] |
0.48[110] |
0.39[111] |
17 |
HRAS |
GTPase HRas |
[112] |
-1.27[113] |
-1.75[114] |
-2.62[115] |
-1.21[116] |
-1.26[117] |
-2.02[118] |
18 |
TUBB3 |
Tubulin beta-3 chain |
[119] |
2.10[120] |
1.26[121] |
-2.98[122] |
0.77[123] |
-2.18[124] |
-7.12[125] |
19 |
MAPK1 |
Mitogen-activated protein kinase 1 |
[126] |
1.45[127] |
1.81[128] |
1.56[129] |
1.59[130] |
1.41[131] |
2.42[132] |
20 |
TUBB6 |
Tubulin beta-6 chain |
[133] |
0.54[134] |
-1.32[135] |
0.21[136] |
1.47[137] |
1.97[138] |
-1.03[139] |
21 |
GNA11 |
Guanine nucleotide-binding protein subunit alpha-11 |
[140] |
-0.93[141] |
-0.79[142] |
-0.91[143] |
-1.44[144] |
-0.48[145] |
-0.61[146] |
22 |
KRAS |
GTPase KRas |
[147] |
-0.78[148] |
-0.58[149] |
0.95[150] |
0.54[151] |
0.37[152] |
1.32[153] |
23 |
SOS1 |
Son of sevenless homolog 1 |
[154] |
-0.36[155] |
1.39[156] |
0.82[157] |
0.59[158] |
-0.01[159] |
1.18[160] |
24 |
TJP1 |
Tight junction protein ZO-1 |
[161] |
0.19[162] |
0.63[163] |
0.33[164] |
1.44[165] |
1.07[166] |
2.48[167] |
25 |
GNAI1 |
Guanine nucleotide-binding protein G(i) subunit alpha-1 |
[168] |
-1.91[169] |
-2.63[170] |
-0.57[171] |
0.96[172] |
0.50[173] |
1.48[174] |
26 |
ITPR2 |
Inositol 1,4,5-trisphosphate receptor type 2 |
[175] |
0.65[176] |
2.33[177] |
0.71[178] |
-0.25[179] |
0.05[180] |
4.51[181] |
27 |
TUBB2B |
Tubulin beta-2B chain |
[182] |
0.40[183] |
-0.50[184] |
-0.61[185] |
-0.69[186] |
-4.44[187] |
-3.56[188] |
28 |
CDK1 |
Cyclin-dependent kinase 1 |
[189] |
0.99[190] |
3.27[191] |
1.93[192] |
2.01[193] |
3.00[194] |
-1.83[195] |
29 |
EGFR |
Epidermal growth factor receptor |
[196] |
-0.96[197] |
-1.11[198] |
1.69[199] |
0.18[200] |
0.96[201] |
3.30[202] |
30 |
PDGFC |
Platelet-derived growth factor C |
[203] |
-1.54[204] |
-0.38[205] |
-0.52[206] |
0.64[207] |
1.05[208] |
0.85[209] |
31 |
MAPK3 |
Mitogen-activated protein kinase 3 |
[210] |
1.59[211] |
1.86[212] |
1.82[213] |
0.17[214] |
0.35[215] |
-0.40[216] |
32 |
MAP2K5 |
Dual specificity mitogen-activated protein kinase kinase 5 |
[217] |
-0.70[218] |
-0.25[219] |
0.68[220] |
-1.02[221] |
-0.45[222] |
0.19[223] |
33 |
SRC |
Proto-oncogene tyrosine-protein kinase Src |
[224] |
2.76[225] |
2.97[226] |
1.89[227] |
2.14[228] |
1.48[229] |
-0.21[230] |
34 |
TUBA1A |
Tubulin alpha-1A chain |
[231] |
1.91[232] |
-1.25[233] |
-4.53[234] |
3.83[235] |
1.51[236] |
0.65[237] |
35 |
PRKACB |
cAMP-dependent protein kinase catalytic subunit beta |
[238] |
-1.10[239] |
-0.10[240] |
1.11[241] |
1.97[242] |
1.00[243] |
2.35[244] |
36 |
ADCY9 |
Adenylate cyclase type 9 |
[245] |
2.36[246] |
1.77[247] |
2.11[248] |
0.70[249] |
0.41[250] |
3.05[251] |
37 |
SOS2 |
Son of sevenless homolog 2 |
[252] |
-0.29[253] |
1.06[254] |
0.21[255] |
1.43[256] |
1.46[257] |
2.48[258] |
38 |
PRKCA |
Protein kinase C alpha type |
[259] |
2.57[260] |
2.84[261] |
3.12[262] |
1.89[263] |
2.42[264] |
2.56[265] |
39 |
MAP3K2 |
Mitogen-activated protein kinase kinase kinase 2 |
[266] |
1.17[267] |
2.60[268] |
2.25[269] |
2.82[270] |
2.26[271] |
4.46[272] |
40 |
ITPR3 |
Inositol 1,4,5-trisphosphate receptor type 3 |
[273] |
5.03[274] |
4.10[275] |
2.51[276] |
2.09[277] |
4.43[278] |
0.87[279] |
41 |
GNAQ |
Guanine nucleotide-binding protein G(q) subunit alpha |
[280] |
-0.19[281] |
0.81[282] |
1.25[283] |
1.33[284] |
1.71[285] |
2.08[286] |
42 |
ADCY6 |
Adenylate cyclase type 6 |
[287] |
1.79[288] |
2.47[289] |
2.36[290] |
2.25[291] |
3.08[292] |
3.28[293] |
43 |
PLCB3 |
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 |
[294] |
1.74[295] |
1.45[296] |
1.83[297] |
2.45[298] |
2.26[299] |
1.37[300] |
44 |
PDGFA |
Platelet-derived growth factor subunit A |
[301] |
-1.27[302] |
-0.83[303] |
1.17[304] |
-0.60[305] |
-1.35[306] |
-0.11[307] |
45 |
MAPK7 |
Mitogen-activated protein kinase 7 |
[308] |
1.17[309] |
0.70[310] |
0.61[311] |
1.55[312] |
1.81[313] |
0.98[314] |
46 |
PLCB1 |
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 |
[315] |
2.53[316] |
4.38[317] |
3.72[318] |
0.52[319] |
1.18[320] |
3.13[321] |
47 |
TUBA8 |
Tubulin alpha-8 chain |
[322] |
-3.70[323] |
-2.16[324] |
-1.59[325] |
-2.31[326] |
-2.77[327] |
-0.08[328] |
48 |
GJA1 |
Gap junction alpha-1 protein |
[329] |
-3.11[330] |
-2.60[331] |
4.55[332] |
4.70[333] |
4.95[334] |
0.30[335] |
49 |
ADCY1 |
Adenylate cyclase type 1 |
[336] |
-1.10[337] |
-2.74[338] |
-3.02[339] |
-2.37[340] |
-2.22[341] |
5.64[342] |
50 |
PDGFB |
Platelet-derived growth factor subunit B |
[343] |
2.79[344] |
2.88[345] |
-0.01[346] |
-0.19[347] |
-0.45[348] |
1.02[349] |
51 |
PRKX |
cAMP-dependent protein kinase catalytic subunit PRKX |
[350] |
-1.91[351] |
-1.91[352] |
2.94[353] |
0.99[354] |
2.70[355] |
2.09[356] |
52 |
ADCY7 |
Adenylate cyclase type 7 |
[357] |
3.25[358] |
3.09[359] |
1.97[360] |
3.05[361] |
2.69[362] |
3.57[363] |
53 |
PDGFRA |
Platelet-derived growth factor receptor alpha |
[364] |
-3.88[365] |
-4.64[366] |
2.92[367] |
0.27[368] |
5.11[369] |
5.96[370] |
54 |
PDGFRB |
Platelet-derived growth factor receptor beta |
[371] |
1.04[372] |
1.66[373] |
-0.88[374] |
1.60[375] |
2.32[376] |
4.06[377] |
55 |
PLCB2 |
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 |
[378] |
-1.88[379] |
-6.44[380] |
-8.36[381] |
-2.19[382] |
-2.74[383] |
2.88[384] |
56 |
ITPR1 |
Inositol 1,4,5-trisphosphate receptor type 1 |
[385] |
2.88[386] |
2.98[387] |
4.06[388] |
2.59[389] |
3.63[390] |
5.29[391] |
57 |
PRKCB |
Protein kinase C beta type |
[392] |
-7.07[393] |
-5.66[394] |
[395] |
2.22[396] |
-2.91[397] |
4.18[398] |
58 |
TUBB8 |
Tubulin beta-8 chain |
[399] |
0.31[400] |
-0.51[401] |
1.87[402] |
-1.08[403] |
-4.78[404] |
-4.09[405] |
59 |
HTR2B |
5-hydroxytryptamine receptor 2B |
[406] |
-2.58[407] |
-1.97[408] |
-2.47[409] |
3.08[410] |
-2.19[411] |
4.39[412] |
60 |
ADCY3 |
Adenylate cyclase type 3 |
[413] |
1.20[414] |
0.18[415] |
3.42[416] |
4.48[417] |
6.18[418] |
4.16[419] |
61 |
TUBA3D |
|
[420] |
-2.26[421] |
-1.30[422] |
-2.23[423] |
-0.74[424] |
-1.87[425] |
0.66[426] |
62 |
ADCY2 |
Adenylate cyclase type 2 |
[427] |
-5.64[428] |
-3.49[429] |
-4.82[430] |
-2.99[431] |
-3.94[432] |
-3.48[433] |
63 |
TUBB1 |
Tubulin beta-1 chain |
[434] |
4.32[435] |
6.39[436] |
2.14[437] |
2.54[438] |
1.37[439] |
4.20[440] |
64 |
TUBB4A |
Tubulin beta-4A chain |
[441] |
1.56[442] |
-2.33[443] |
4.12[444] |
3.37[445] |
2.11[446] |
2.49[447] |
65 |
TUBA3E |
Tubulin alpha-3E chain |
[448] |
[449] |
-4.82[450] |
-4.67[451] |
-4.94[452] |
-2.41[453] |
0.21[454] |
66 |
LPAR1 |
Lysophosphatidic acid receptor 1 |
[455] |
-4.87[456] |
[457] |
-1.40[458] |
5.38[459] |
5.86[460] |
4.59[461] |
67 |
TUBA3C |
Tubulin alpha-3C/D chain |
[462] |
[463] |
-4.30[464] |
[465] |
0.93[466] |
-5.29[467] |
-3.59[468] |
68 |
ADRB1 |
Beta-1 adrenergic receptor |
[469] |
-4.33[470] |
[471] |
2.18[472] |
0.27[473] |
-2.60[474] |
2.81[475] |
69 |
ADCY5 |
Adenylate cyclase type 5 |
[476] |
-0.11[477] |
1.11[478] |
2.06[479] |
0.39[480] |
1.68[481] |
7.02[482] |
70 |
PRKCG |
Protein kinase C gamma type |
[483] |
-1.08[484] |
-0.19[485] |
-2.64[486] |
-1.32[487] |
-1.24[488] |
[489] |
71 |
PDGFD |
Platelet-derived growth factor D |
[490] |
2.11[491] |
-2.48[492] |
-4.75[493] |
2.57[494] |
4.29[495] |
6.72[496] |
72 |
HTR2A |
5-hydroxytryptamine receptor 2A |
[497] |
[498] |
-1.05[499] |
[500] |
-2.64[501] |
-0.02[502] |
5.38[503] |
73 |
PRKG1 |
cGMP-dependent protein kinase 1 |
[504] |
-0.42[505] |
[506] |
1.10[507] |
2.92[508] |
5.00[509] |
7.15[510] |
74 |
PLCB4 |
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 |
[511] |
-0.01[512] |
0.06[513] |
0.99[514] |
9.37[515] |
7.26[516] |
4.44[517] |
75 |
PRKG2 |
cGMP-dependent protein kinase 2 |
[518] |
2.64[519] |
[520] |
[521] |
6.53[522] |
0.99[523] |
2.68[524] |
76 |
GUCY1A2 |
Guanylate cyclase soluble subunit alpha-2 |
[525] |
0.99[526] |
2.31[527] |
7.92[528] |
9.97[529] |
4.68[530] |
11.21[531] |
77 |
ADCY4 |
Adenylate cyclase type 4 |
[532] |
-0.17[533] |
-1.02[534] |
1.54[535] |
[536] |
[537] |
9.01[538] |
78 |
EGF |
Pro-epidermal growth factor |
[539] |
1.70[540] |
3.71[541] |
7.25[542] |
8.77[543] |
6.35[544] |
2.22[545] |
79 |
GRM1 |
Metabotropic glutamate receptor 1 |
[546] |
1.99[547] |
[548] |
0.30[549] |
5.31[550] |
3.22[551] |
3.77[552] |
80 |
TUBB7P |
|
[553] |
[554] |
[555] |
[556] |
[557] |
[558] |
[559] |
81 |
GRM5 |
Metabotropic glutamate receptor 5 |
[560] |
[561] |
[562] |
[563] |
[564] |
[565] |
[566] |
82 |
HTR2C |
5-hydroxytryptamine receptor 2C |
[567] |
[568] |
[569] |
[570] |
[571] |
[572] |
[573] |
83 |
DRD1 |
D(1A) dopamine receptor |
[574] |
[575] |
[576] |
[577] |
[578] |
[579] |
[580] |
84 |
GUCY1A1 |
|
[581] |
[582] |
[583] |
[584] |
[585] |
[586] |
[587] |
85 |
GJD2 |
Gap junction delta-2 protein |
[588] |
[589] |
[590] |
[591] |
[592] |
[593] |
[594] |
86 |
TUBAL3 |
Tubulin alpha chain-like 3 |
[595] |
[596] |
[597] |
[598] |
[599] |
[600] |
[601] |
87 |
DRD2 |
D(2) dopamine receptor |
[602] |
[603] |
[604] |
[605] |
[606] |
[607] |
[608] |
88 |
ADCY8 |
Adenylate cyclase type 8 |
[609] |
[610] |
[611] |
[612] |
[613] |
[614] |
[615] |
89 |
GUCY1B1 |
|
[616] |
[617] |
[618] |
[619] |
[620] |
[621] |
[622] |
90 |
PRKACG |
cAMP-dependent protein kinase catalytic subunit gamma |
[623] |
[624] |
[625] |
[626] |
[627] |
[628] |
[629] |
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