KEGG_GALACTOSE_METABOLISM Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 UGP2 UTP--glucose-1-phosphate uridylyltransferase [1] -2.07[2] -1.54[3] -2.15[4] -1.96[5] -2.54[6] -0.41[7]
2 PGM1 Phosphoglucomutase-1 [8] -1.30[9] -0.57[10] -0.08[11] -1.33[12] -1.96[13] 0.57[14]
3 GALK1 Galactokinase [15] -1.09[16] -0.64[17] -0.87[18] -2.27[19] -2.93[20] -0.27[21]
4 B4GALT1 Beta-1,4-galactosyltransferase 1 [22] 0.00[23] -0.21[24] 0.71[25] -0.21[26] 1.50[27] 0.48[28]
5 PFKL ATP-dependent 6-phosphofructokinase, liver type [29] 1.21[30] 1.17[31] 0.99[32] 0.41[33] -0.11[34] 0.55[35]
6 GALE UDP-glucose 4-epimerase [36] 0.00[37] 1.23[38] -0.68[39] -0.38[40] -1.33[41] -0.79[42]
7 GALT Galactose-1-phosphate uridylyltransferase [43] -2.11[44] -1.60[45] -1.49[46] -3.42[47] -2.85[48] 0.48[49]
8 GLB1 Beta-galactosidase [50] 0.77[51] 0.32[52] 1.32[53] -0.67[54] 0.02[55] -0.04[56]
9 B4GALT2 Beta-1,4-galactosyltransferase 2 [57] 0.70[58] 0.45[59] 0.25[60] -0.62[61] -1.13[62] -2.15[63]
10 GAA Lysosomal alpha-glucosidase [64] 2.17[65] 1.43[66] 1.96[67] 0.00[68] 0.51[69] 0.82[70]
11 PFKP ATP-dependent 6-phosphofructokinase, platelet type [71] -0.07[72] -1.92[73] -6.61[74] 3.38[75] 1.95[76] -3.11[77]
12 GLA Alpha-galactosidase A [78] 0.05[79] -0.69[80] 0.43[81] 0.04[82] -0.25[83] -1.71[84]
13 AKR1B1 Aldose reductase [85] 2.80[86] 1.62[87] -2.90[88] 2.80[89] 3.55[90] -1.25[91]
14 PGM2 Phosphoglucomutase-2 [92] 0.89[93] 0.91[94] 1.06[95] 0.66[96] 1.59[97] -0.16[98]
15 GALK2 N-acetylgalactosamine kinase [99] -0.20[100] 0.94[101] 1.72[102] -0.10[103] -0.26[104] 1.44[105]
16 HK1 Hexokinase-1 [106] 1.04[107] -3.95[108] -5.25[109] 4.37[110] 4.33[111] 0.75[112]
17 PFKM ATP-dependent 6-phosphofructokinase, muscle type [113] -1.45[114] -0.94[115] 4.03[116] 3.18[117] 3.49[118] 0.75[119]
18 GANC Neutral alpha-glucosidase C [120] 0.90[121] 0.74[122] 0.69[123] 0.34[124] 0.80[125] 2.49[126]
19 HK2 Hexokinase-2 [127] 6.01[128] 6.26[129] 5.30[130] 3.70[131] 4.39[132] 0.38[133]
20 GCK Glucokinase [134] -7.83[135] -5.92[136] -9.15[137] -7.09[138] -5.23[139] 1.77[140]
21 HK3 Hexokinase-3 [141] -7.72[142] -7.74[143] -8.69[144] -5.67[145] -8.95[146] 2.81[147]
22 MGAM Maltase-glucoamylase, intestinal [148] -3.77[149] -1.94[150] 4.58[151] -5.61[152] -1.40[153] 1.62[154]
23 G6PC2 Glucose-6-phosphatase 2 [155] [156] [157] [158] [159] [160] [161]
24 LCT Lactase-phlorizin hydrolase [162] [163] [164] [165] [166] [167] [168]
25 LALBA Alpha-lactalbumin [169] [170] [171] [172] [173] [174] [175]
26 G6PC1 [176] [177] [178] [179] [180] [181] [182]
[1]
ref_hepatocyte UGP2
Mean 149
Standard deviation 1.1e+02
Values 46 3.1e+02 1.6e+02 44 1.9e+02
[2]
HepG2 UGP2
Mean 72.3
Standard deviation 27
Values 53 92
[3]
HepG2.C3A UGP2
Mean 98.6
Standard deviation 16
Values 87 1.1e+02
[4]
HuH.7 UGP2
Mean 63.6
Standard deviation 4.1
Values 60 68 63
[5]
SNU475 UGP2
Mean 79
Standard deviation 17
Values 91 67
[6]
THLE UGP2
Mean 63.1
Standard deviation 2.6
Values 65 61
[7]
liver UGP2
Mean 178
Standard deviation 1.6e+02
Values 85 4.1e+02 1.3e+02 89
[8]
ref_hepatocyte PGM1
Mean 48.7
Standard deviation 37
Values 17 38 81 13 94
[9]
HepG2 PGM1
Mean 40.3
Standard deviation 11
Values 32 48
[10]
HepG2.C3A PGM1
Mean 63.1
Standard deviation 8.8
Values 69 57
[11]
HuH.7 PGM1
Mean 87
Standard deviation 8.2
Values 96 80 84
[12]
SNU475 PGM1
Mean 39.9
Standard deviation 9.8
Values 47 33
[13]
THLE PGM1
Mean 30.8
Standard deviation 0.38
Values 31 31
[14]
liver PGM1
Mean 114
Standard deviation 21
Values 91 1.3e+02 1.3e+02 1e+02
[15]
ref_hepatocyte GALK1
Mean 31.3
Standard deviation 20
Values 23 18 57 10 48
[16]
HepG2 GALK1
Mean 29.8
Standard deviation 8.4
Values 36 24
[17]
HepG2.C3A GALK1
Mean 38.7
Standard deviation 11
Values 47 31
[18]
HuH.7 GALK1
Mean 32.4
Standard deviation 1.1
Values 32 31 34
[19]
SNU475 GALK1
Mean 13.3
Standard deviation 0.12
Values 13 13
[20]
THLE GALK1
Mean 10.1
Standard deviation 0.32
Values 9.9 10
[21]
liver GALK1
Mean 41.4
Standard deviation 44
Values 8.8 1.1e+02 25 25
[22]
ref_hepatocyte B4GALT1
Mean 24.8
Standard deviation 5.2
Values 17 26 31 28 23
[23]
HepG2 B4GALT1
Mean 50.3
Standard deviation 11
Values 58 42
[24]
HepG2.C3A B4GALT1
Mean 41.3
Standard deviation 12
Values 50 32
[25]
HuH.7 B4GALT1
Mean 76.8
Standard deviation 16
Values 83 90 58
[26]
SNU475 B4GALT1
Mean 44.1
Standard deviation 8.5
Values 50 38
[27]
THLE B4GALT1
Mean 172
Standard deviation 9.4
Values 1.7e+02 1.8e+02
[28]
liver B4GALT1
Mean 55
Standard deviation 12
Values 46 52 73 49
[29]
ref_hepatocyte PFKL
Mean 23.2
Standard deviation 11
Values 40 17 25 9.3 25
[30]
HepG2 PFKL
Mean 109
Standard deviation 8.2
Values 1.1e+02 1e+02
[31]
HepG2.C3A PFKL
Mean 101
Standard deviation 29
Values 1.2e+02 80
[32]
HuH.7 PFKL
Mean 87.4
Standard deviation 22
Values 1e+02 62 99
[33]
SNU475 PFKL
Mean 63.3
Standard deviation 25
Values 81 46
[34]
THLE PFKL
Mean 52.7
Standard deviation 1.5
Values 52 54
[35]
liver PFKL
Mean 53.7
Standard deviation 15
Values 40 55 73 47
[36]
ref_hepatocyte GALE
Mean 19.2
Standard deviation 3.1
Values 21 14 21 19 22
[37]
HepG2 GALE
Mean 38.9
Standard deviation 8.2
Values 45 33
[38]
HepG2.C3A GALE
Mean 86.4
Standard deviation 3.4
Values 89 84
[39]
HuH.7 GALE
Mean 22.6
Standard deviation 7.4
Values 20 17 31
[40]
SNU475 GALE
Mean 30.3
Standard deviation 2.2
Values 32 29
[41]
THLE GALE
Mean 18.7
Standard deviation 2.3
Values 17 20
[42]
liver GALE
Mean 17.7
Standard deviation 8.6
Values 12 25 25 9
[43]
ref_hepatocyte GALT
Mean 18.7
Standard deviation 18
Values 7.8 4.2 42 4.3 35
[44]
HepG2 GALT
Mean 8.81
Standard deviation 0.24
Values 8.6 9
[45]
HepG2.C3A GALT
Mean 11.9
Standard deviation 2.5
Values 14 10
[46]
HuH.7 GALT
Mean 12.6
Standard deviation 1.5
Values 11 12 14
[47]
SNU475 GALT
Mean 3.59
Standard deviation 0.62
Values 4 3.2
[48]
THLE GALT
Mean 6.37
Standard deviation 0.48
Values 6.7 6
[49]
liver GALT
Mean 41.3
Standard deviation 25
Values 19 74 47 26
[50]
ref_hepatocyte GLB1
Mean 15.3
Standard deviation 5.7
Values 22 9.9 18 8.6 18
[51]
HepG2 GLB1
Mean 53.1
Standard deviation 4.7
Values 56 50
[52]
HepG2.C3A GLB1
Mean 36.7
Standard deviation 8.2
Values 42 31
[53]
HuH.7 GLB1
Mean 72.4
Standard deviation 9.9
Values 62 81 75
[54]
SNU475 GLB1
Mean 19.7
Standard deviation 1.4
Values 19 21
[55]
THLE GLB1
Mean 38.2
Standard deviation 4.9
Values 35 42
[56]
liver GLB1
Mean 23.6
Standard deviation 8.2
Values 20 23 35 16
[57]
ref_hepatocyte B4GALT2
Mean 11.8
Standard deviation 6.8
Values 6.1 8.9 15 22 6.9
[58]
HepG2 B4GALT2
Mean 39.1
Standard deviation 4.7
Values 42 36
[59]
HepG2.C3A B4GALT2
Mean 30.9
Standard deviation 7.3
Values 36 26
[60]
HuH.7 B4GALT2
Mean 26.6
Standard deviation 8.3
Values 31 17 32
[61]
SNU475 B4GALT2
Mean 15.8
Standard deviation 2.1
Values 17 14
[62]
THLE B4GALT2
Mean 13.3
Standard deviation 1.8
Values 12 15
[63]
liver B4GALT2
Mean 4.24
Standard deviation 1.8
Values 6.5 2.3 3.7 4.4
[64]
ref_hepatocyte GAA
Mean 10.4
Standard deviation 7.9
Values 8.9 2.6 17 3.6 20
[65]
HepG2 GAA
Mean 95.6
Standard deviation 35
Values 1.2e+02 71
[66]
HepG2.C3A GAA
Mean 54.2
Standard deviation 24
Values 71 38
[67]
HuH.7 GAA
Mean 77
Standard deviation 11
Values 84 65 82
[68]
SNU475 GAA
Mean 21.5
Standard deviation 6.3
Values 26 17
[69]
THLE GAA
Mean 36.4
Standard deviation 5.3
Values 40 33
[70]
liver GAA
Mean 29.3
Standard deviation 14
Values 17 37 46 17
[71]
ref_hepatocyte PFKP
Mean 9.86
Standard deviation 17
Values 1 39 0.3 8.4 0.58
[72]
HepG2 PFKP
Mean 19
Standard deviation 13
Values 28 9.8
[73]
HepG2.C3A PFKP
Mean 5.02
Standard deviation 1
Values 4.3 5.8
[74]
HuH.7 PFKP
Mean 0.191
Standard deviation 0.11
Values 0.24 0.27 0.066
[75]
SNU475 PFKP
Mean 212
Standard deviation 73
Values 2.6e+02 1.6e+02
[76]
THLE PFKP
Mean 93.5
Standard deviation 18
Values 81 1.1e+02
[77]
liver PFKP
Mean 1.82
Standard deviation 0.73
Values 2 1.1 2.8 1.4
[78]
ref_hepatocyte GLA
Mean 9.06
Standard deviation 4.8
Values 5.9 12 16 7.9 3.7
[79]
HepG2 GLA
Mean 19.1
Standard deviation 1.1
Values 18 20
[80]
HepG2.C3A GLA
Mean 10.8
Standard deviation 4.5
Values 7.6 14
[81]
HuH.7 GLA
Mean 23.1
Standard deviation 7.4
Values 22 17 31
[82]
SNU475 GLA
Mean 19.1
Standard deviation 7.5
Values 14 24
[83]
THLE GLA
Mean 18.7
Standard deviation 1.1
Values 18 19
[84]
liver GLA
Mean 4.39
Standard deviation 1.9
Values 3.8 4.5 6.9 2.4
[85]
ref_hepatocyte AKR1B1
Mean 6.91
Standard deviation 5.9
Values 12 15 3.4 2.7 2
[86]
HepG2 AKR1B1
Mean 98.1
Standard deviation 19
Values 1.1e+02 85
[87]
HepG2.C3A AKR1B1
Mean 40.9
Standard deviation 16
Values 29 52
[88]
HuH.7 AKR1B1
Mean 1.75
Standard deviation 0.56
Values 2.2 1.1 1.9
[89]
SNU475 AKR1B1
Mean 99.2
Standard deviation 35
Values 75 1.2e+02
[90]
THLE AKR1B1
Mean 199
Standard deviation 6.6
Values 1.9e+02 2e+02
[91]
liver AKR1B1
Mean 4.63
Standard deviation 2.8
Values 1.8 6.6 7.5 2.6
[92]
ref_hepatocyte PGM2
Mean 4.67
Standard deviation 2.7
Values 6.5 8.2 1.3 4.4 2.9
[93]
HepG2 PGM2
Mean 17.6
Standard deviation 5.6
Values 14 22
[94]
HepG2.C3A PGM2
Mean 16.8
Standard deviation 7.6
Values 11 22
[95]
HuH.7 PGM2
Mean 18.4
Standard deviation 3.6
Values 20 14 20
[96]
SNU475 PGM2
Mean 15.2
Standard deviation 0.74
Values 16 15
[97]
THLE PGM2
Mean 34.5
Standard deviation 5.3
Values 31 38
[98]
liver PGM2
Mean 6.66
Standard deviation 1.3
Values 8.6 5.5 6 6.5
[99]
ref_hepatocyte GALK2
Mean 4.15
Standard deviation 2.7
Values 2.3 3.4 8.2 1.4 5.4
[100]
HepG2 GALK2
Mean 7.33
Standard deviation 0.4
Values 7 7.6
[101]
HepG2.C3A GALK2
Mean 15.4
Standard deviation 0.33
Values 16 15
[102]
HuH.7 GALK2
Mean 25.9
Standard deviation 2.2
Values 23 27 27
[103]
SNU475 GALK2
Mean 7.99
Standard deviation 1
Values 8.7 7.3
[104]
THLE GALK2
Mean 8.49
Standard deviation 1.1
Values 7.7 9.3
[105]
liver GALK2
Mean 17.8
Standard deviation 3
Values 19 15 22 16
[106]
ref_hepatocyte HK1
Mean 1.86
Standard deviation 1.3
Values 0.099 2.2 1.9 3.7 1.4
[107]
HepG2 HK1
Mean 7.77
Standard deviation 3.6
Values 10 5.2
[108]
HepG2.C3A HK1
Mean 0.233
Standard deviation 0.056
Values 0.27 0.19
[109]
HuH.7 HK1
Mean 0.0926
Standard deviation 0.049
Values 0.13 0.11 0.037
[110]
SNU475 HK1
Mean 79.1
Standard deviation 12
Values 71 87
[111]
THLE HK1
Mean 91.7
Standard deviation 17
Values 80 1e+02
[112]
liver HK1
Mean 4.98
Standard deviation 1.7
Values 6.3 2.9 4.4 6.3
[113]
ref_hepatocyte PFKM
Mean 1.41
Standard deviation 1.5
Values 0.15 4 1.1 0.38 1.5
[114]
HepG2 PFKM
Mean 1.05
Standard deviation 0.053
Values 1.1 1
[115]
HepG2.C3A PFKM
Mean 1.41
Standard deviation 0.22
Values 1.3 1.6
[116]
HuH.7 PFKM
Mean 43.4
Standard deviation 9.4
Values 48 33 49
[117]
SNU475 PFKM
Mean 26.2
Standard deviation 3.8
Values 29 23
[118]
THLE PFKM
Mean 38.8
Standard deviation 5.8
Values 35 43
[119]
liver PFKM
Mean 3.75
Standard deviation 0.6
Values 4 3.9 4.2 2.9
[120]
ref_hepatocyte GANC
Mean 1.04
Standard deviation 0.66
Values 2.1 0.81 0.91 0.33 1
[121]
HepG2 GANC
Mean 3.94
Standard deviation 1.5
Values 2.9 5
[122]
HepG2.C3A GANC
Mean 3.34
Standard deviation 0.42
Values 3 3.6
[123]
HuH.7 GANC
Mean 3.17
Standard deviation 0.44
Values 3.1 3.7 2.8
[124]
SNU475 GANC
Mean 2.71
Standard deviation 0.95
Values 3.4 2
[125]
THLE GANC
Mean 4.46
Standard deviation 1.2
Values 3.6 5.3
[126]
liver GANC
Mean 9.3
Standard deviation 3.1
Values 11 8.3 5.3 12
[127]
ref_hepatocyte HK2
Mean 0.685
Standard deviation 0.83
Values 2.1 0.034 0.21 0.74 0.36
[128]
HepG2 HK2
Mean 89.6
Standard deviation 21
Values 75 1e+02
[129]
HepG2.C3A HK2
Mean 101
Standard deviation 25
Values 1.2e+02 83
[130]
HuH.7 HK2
Mean 51
Standard deviation 6.9
Values 52 57 44
[131]
SNU475 HK2
Mean 18.3
Standard deviation 3.2
Values 16 21
[132]
THLE HK2
Mean 35.2
Standard deviation 8.1
Values 29 41
[133]
liver HK2
Mean 1.42
Standard deviation 0.76
Values 2.2 0.52 1.1 1.9
[134]
ref_hepatocyte GCK
Mean 0.642
Standard deviation 1.1
Values 0 0 0.7 0 2.5
[135]
HepG2 GCK
Mean 0.00573
Standard deviation 0.0081
Values 0.011 0
[136]
HepG2.C3A GCK
Mean 0.0204
Standard deviation 0.0014
Values 0.019 0.021
[137]
HuH.7 GCK
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[138]
SNU475 GCK
Mean 0.00971
Standard deviation 0.00061
Values 0.0093 0.01
[139]
THLE GCK
Mean 0.042
Standard deviation 0.00081
Values 0.041 0.043
[140]
liver GCK
Mean 3.47
Standard deviation 6.5
Values 0.17 13 0.13 0.38
[141]
ref_hepatocyte HK3
Mean 0.594
Standard deviation 0.77
Values 0 0.036 1 0.17 1.8
[142]
HepG2 HK3
Mean 0.00573
Standard deviation 0.0081
Values 0.011 0
[143]
HepG2.C3A HK3
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[144]
HuH.7 HK3
Mean 0.00273
Standard deviation 0.0047
Values 0.0082 0 0
[145]
SNU475 HK3
Mean 0.0241
Standard deviation 0.0053
Values 0.028 0.02
[146]
THLE HK3
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[147]
liver HK3
Mean 6.61
Standard deviation 1.6
Values 7.5 4.7 6 8.3
[148]
ref_hepatocyte MGAM
Mean 0.452
Standard deviation 0.68
Values 0.054 0.58 0.043 1.6 0
[149]
HepG2 MGAM
Mean 0.0673
Standard deviation 0.014
Values 0.057 0.077
[150]
HepG2.C3A MGAM
Mean 0.227
Standard deviation 0.088
Values 0.17 0.29
[151]
HuH.7 MGAM
Mean 20.5
Standard deviation 8.8
Values 17 31 14
[152]
SNU475 MGAM
Mean 0.019
Standard deviation 0.013
Values 0.028 0.01
[153]
THLE MGAM
Mean 0.421
Standard deviation 0.052
Values 0.38 0.46
[154]
liver MGAM
Mean 2.2
Standard deviation 2.8
Values 1.9 0.33 0.36 6.2
[155]
ref_hepatocyte G6PC2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[156]
HepG2 G6PC2
Mean 0
Standard deviation 0
Values 0 0
[157]
HepG2.C3A G6PC2
Mean 0
Standard deviation 0
Values 0 0
[158]
HuH.7 G6PC2
Mean 0.0429
Standard deviation 0.045
Values 0.09 0.039 0
[159]
SNU475 G6PC2
Mean 0
Standard deviation 0
Values 0 0
[160]
THLE G6PC2
Mean 0
Standard deviation 0
Values 0 0
[161]
liver G6PC2
Mean 0.0512
Standard deviation 0.061
Values 0.086 0 0 0.12
[162]
ref_hepatocyte LCT
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[163]
HepG2 LCT
Mean 0.0122
Standard deviation 0.001
Values 0.011 0.013
[164]
HepG2.C3A LCT
Mean 0.00972
Standard deviation 0.014
Values 0.019 0
[165]
HuH.7 LCT
Mean 0.0351
Standard deviation 0.033
Values 0.041 0.064 0
[166]
SNU475 LCT
Mean 0.0226
Standard deviation 0.025
Values 0.0046 0.041
[167]
THLE LCT
Mean 0.0109
Standard deviation 0.0071
Values 0.0059 0.016
[168]
liver LCT
Mean 0.07
Standard deviation 0.082
Values 0.071 0.024 0 0.19
[169]
ref_hepatocyte LALBA
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[170]
HepG2 LALBA
Missing
[171]
HepG2.C3A LALBA
Missing
[172]
HuH.7 LALBA
Missing
[173]
SNU475 LALBA
Missing
[174]
THLE LALBA
Missing
[175]
liver LALBA
Missing
[176]
ref_hepatocyte G6PC1
Missing
[177]
HepG2 G6PC1
Missing
[178]
HepG2.C3A G6PC1
Missing
[179]
HuH.7 G6PC1
Missing
[180]
SNU475 G6PC1
Missing
[181]
THLE G6PC1
Missing
[182]
liver G6PC1
Missing