KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS |
Return to index |
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Order |
Gene |
Description |
ref_hepatocyte |
HepG2 |
HepG2.C3A |
HuH.7 |
SNU475 |
THLE |
liver |
1 |
CFL1 |
Cofilin-1 |
[1] |
-0.34[2] |
-1.27[3] |
-1.25[4] |
-0.63[5] |
-0.31[6] |
-0.48[7] |
2 |
ARPC3 |
Actin-related protein 2/3 complex subunit 3 |
[8] |
-1.59[9] |
-1.00[10] |
-1.45[11] |
-1.59[12] |
-1.65[13] |
-2.04[14] |
3 |
CDC42 |
Cell division control protein 42 homolog |
[15] |
-0.90[16] |
-0.10[17] |
-1.06[18] |
-0.70[19] |
-1.17[20] |
-1.62[21] |
4 |
ARPC2 |
Actin-related protein 2/3 complex subunit 2 |
[22] |
-0.46[23] |
-0.59[24] |
-1.04[25] |
-0.54[26] |
-0.36[27] |
-1.31[28] |
5 |
GSN |
Gelsolin |
[29] |
0.84[30] |
0.67[31] |
-2.35[32] |
-1.58[33] |
-1.91[34] |
-1.45[35] |
6 |
ARPC5L |
Actin-related protein 2/3 complex subunit 5-like protein |
[36] |
-2.75[37] |
-2.50[38] |
-2.85[39] |
-2.53[40] |
-1.83[41] |
-2.40[42] |
7 |
RAC1 |
Ras-related C3 botulinum toxin substrate 1 |
[43] |
-0.47[44] |
-0.71[45] |
0.04[46] |
-0.15[47] |
0.09[48] |
-0.50[49] |
8 |
ARPC5 |
Actin-related protein 2/3 complex subunit 5 |
[50] |
-0.50[51] |
-1.06[52] |
-1.63[53] |
0.72[54] |
0.15[55] |
-0.48[56] |
9 |
ARPC1A |
Actin-related protein 2/3 complex subunit 1A |
[57] |
-0.66[58] |
-1.07[59] |
-0.30[60] |
-0.48[61] |
-0.54[62] |
-0.43[63] |
10 |
ARPC4 |
Actin-related protein 2/3 complex subunit 4 |
[64] |
-1.48[65] |
-1.91[66] |
-0.28[67] |
-1.64[68] |
-1.10[69] |
-1.44[70] |
11 |
CFL2 |
Cofilin-2 |
[71] |
-0.51[72] |
-1.89[73] |
-0.22[74] |
-0.20[75] |
-1.18[76] |
0.39[77] |
12 |
AKT1 |
RAC-alpha serine/threonine-protein kinase |
[78] |
0.00[79] |
-0.14[80] |
-1.17[81] |
-0.22[82] |
0.06[83] |
0.22[84] |
13 |
ARPC1B |
Actin-related protein 2/3 complex subunit 1B |
[85] |
-0.08[86] |
-0.30[87] |
-1.24[88] |
0.78[89] |
0.06[90] |
-0.52[91] |
14 |
VASP |
Vasodilator-stimulated phosphoprotein |
[92] |
-0.22[93] |
-0.52[94] |
-0.12[95] |
-0.40[96] |
-1.02[97] |
-2.46[98] |
15 |
MAP2K1 |
Dual specificity mitogen-activated protein kinase kinase 1 |
[99] |
-1.00[100] |
-1.25[101] |
-0.62[102] |
-0.71[103] |
0.05[104] |
-0.73[105] |
16 |
MARCKSL1 |
MARCKS-related protein |
[106] |
1.42[107] |
0.96[108] |
1.64[109] |
-0.60[110] |
-0.13[111] |
-1.27[112] |
17 |
ARF6 |
ADP-ribosylation factor 6 |
[113] |
-0.51[114] |
-0.34[115] |
0.81[116] |
-0.45[117] |
0.35[118] |
0.51[119] |
18 |
MARCKS |
Myristoylated alanine-rich C-kinase substrate |
[120] |
0.30[121] |
1.18[122] |
1.68[123] |
1.58[124] |
0.54[125] |
-0.99[126] |
19 |
CRK |
Adapter molecule crk |
[127] |
-0.28[128] |
-0.26[129] |
-0.15[130] |
-0.41[131] |
0.24[132] |
1.31[133] |
20 |
RPS6KB2 |
Ribosomal protein S6 kinase beta-2 |
[134] |
[135] |
[136] |
[137] |
[138] |
[139] |
[140] |
21 |
RAF1 |
RAF proto-oncogene serine/threonine-protein kinase |
[141] |
-0.14[142] |
0.36[143] |
1.67[144] |
-0.35[145] |
0.77[146] |
1.56[147] |
22 |
DNM2 |
Dynamin-2 |
[148] |
1.93[149] |
0.96[150] |
1.27[151] |
0.79[152] |
1.31[153] |
1.23[154] |
23 |
SPHK1 |
Sphingosine kinase 1 |
[155] |
1.50[156] |
2.28[157] |
-0.16[158] |
-2.37[159] |
0.15[160] |
-4.54[161] |
24 |
MAPK1 |
Mitogen-activated protein kinase 1 |
[162] |
1.63[163] |
1.86[164] |
1.73[165] |
1.68[166] |
1.58[167] |
2.24[168] |
25 |
AKT2 |
RAC-beta serine/threonine-protein kinase |
[169] |
0.88[170] |
1.25[171] |
1.42[172] |
0.69[173] |
0.74[174] |
1.59[175] |
26 |
WASL |
Neural Wiskott-Aldrich syndrome protein |
[176] |
-0.56[177] |
0.60[178] |
1.05[179] |
0.94[180] |
0.35[181] |
1.59[182] |
27 |
VAV2 |
Guanine nucleotide exchange factor VAV2 |
[183] |
1.22[184] |
1.56[185] |
1.10[186] |
-0.70[187] |
-0.03[188] |
0.98[189] |
28 |
CRKL |
Crk-like protein |
[190] |
1.63[191] |
1.81[192] |
2.46[193] |
0.96[194] |
1.41[195] |
1.92[196] |
29 |
PIK3R1 |
Phosphatidylinositol 3-kinase regulatory subunit alpha |
[197] |
-0.55[198] |
-0.34[199] |
0.79[200] |
1.90[201] |
1.65[202] |
3.47[203] |
30 |
DNM1L |
Dynamin-1-like protein |
[204] |
0.47[205] |
1.37[206] |
1.45[207] |
2.54[208] |
1.78[209] |
1.36[210] |
31 |
PIP5K1A |
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha |
[211] |
1.02[212] |
1.16[213] |
1.33[214] |
2.12[215] |
2.07[216] |
0.38[217] |
32 |
WASF2 |
Wiskott-Aldrich syndrome protein family member 2 |
[218] |
1.93[219] |
1.26[220] |
2.32[221] |
2.77[222] |
2.31[223] |
2.03[224] |
33 |
FCGR3A |
Low affinity immunoglobulin gamma Fc region receptor III-A |
[225] |
[226] |
[227] |
[228] |
-10.16[229] |
[230] |
1.35[231] |
34 |
LYN |
Tyrosine-protein kinase Lyn |
[232] |
-0.94[233] |
-1.03[234] |
-0.45[235] |
0.89[236] |
-0.10[237] |
0.48[238] |
35 |
PIK3R2 |
Phosphatidylinositol 3-kinase regulatory subunit beta |
[239] |
1.80[240] |
2.11[241] |
2.76[242] |
0.54[243] |
1.35[244] |
0.17[245] |
36 |
MAPK3 |
Mitogen-activated protein kinase 3 |
[246] |
1.77[247] |
1.91[248] |
1.99[249] |
0.26[250] |
0.53[251] |
-0.58[252] |
37 |
PIP4K2B |
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta |
[253] |
2.46[254] |
2.12[255] |
2.44[256] |
2.28[257] |
1.83[258] |
1.63[259] |
38 |
RAC2 |
Ras-related C3 botulinum toxin substrate 2 |
[260] |
-1.79[261] |
-7.69[262] |
-8.25[263] |
-1.56[264] |
2.50[265] |
-0.77[266] |
39 |
LIMK2 |
LIM domain kinase 2 |
[267] |
1.42[268] |
1.89[269] |
2.08[270] |
0.21[271] |
1.10[272] |
1.75[273] |
40 |
PRKCD |
Protein kinase C delta type |
[274] |
1.02[275] |
1.36[276] |
0.88[277] |
-0.67[278] |
0.74[279] |
-0.60[280] |
41 |
PLCG1 |
1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase gamma-1 |
3.41[281] |
3.12[282] |
2.50[283] |
2.66[284] |
2.40[285] |
0.80[286] |
42 |
SPHK2 |
Sphingosine kinase 2 |
[287] |
-0.24[288] |
0.04[289] |
-0.20[290] |
0.00[291] |
-0.33[292] |
0.87[293] |
43 |
RPS6KB1 |
Ribosomal protein S6 kinase beta-1 |
[294] |
[295] |
[296] |
[297] |
[298] |
[299] |
[300] |
44 |
PIK3CB |
Phosphatidylinositol
4,5-bisphosphate 3-kinase catalytic subunit beta isoform |
1.14[301] |
1.73[302] |
1.94[303] |
0.89[304] |
1.29[305] |
1.62[306] |
45 |
ASAP3 |
Arf-GAP with SH3 domain, ANK repeat
and PH domain-containing protein 3 |
1.36[307] |
2.43[308] |
2.03[309] |
1.92[310] |
1.78[311] |
2.10[312] |
46 |
LIMK1 |
LIM domain kinase 1 |
[313] |
2.23[314] |
1.21[315] |
0.83[316] |
3.34[317] |
1.83[318] |
-1.02[319] |
47 |
PRKCA |
Protein kinase C alpha type |
[320] |
2.76[321] |
2.89[322] |
3.29[323] |
1.98[324] |
2.60[325] |
2.38[326] |
48 |
ASAP1 |
Arf-GAP with SH3 domain, ANK repeat
and PH domain-containing protein 1 |
2.37[327] |
2.01[328] |
2.14[329] |
4.05[330] |
3.46[331] |
2.19[332] |
49 |
PAK1 |
Serine/threonine-protein kinase PAK 1 |
[333] |
-0.09[334] |
-0.76[335] |
1.69[336] |
-2.02[337] |
2.01[338] |
0.73[339] |
50 |
PLD1 |
Phospholipase D1 |
[340] |
2.34[341] |
3.15[342] |
3.68[343] |
0.88[344] |
1.73[345] |
2.52[346] |
51 |
PLD2 |
Phospholipase D2 |
[347] |
0.88[348] |
1.50[349] |
1.43[350] |
0.59[351] |
0.70[352] |
1.36[353] |
52 |
ASAP2 |
Arf-GAP with SH3 domain, ANK repeat
and PH domain-containing protein 2 |
2.38[354] |
2.24[355] |
1.57[356] |
1.95[357] |
3.62[358] |
0.82[359] |
53 |
PIK3CA |
Phosphatidylinositol
4,5-bisphosphate 3-kinase catalytic subunit alpha isoform |
-0.46[360] |
1.27[361] |
1.50[362] |
0.96[363] |
1.42[364] |
2.38[365] |
54 |
PIK3CD |
Phosphatidylinositol
4,5-bisphosphate 3-kinase catalytic subunit delta isoform |
1.81[366] |
2.99[367] |
-0.78[368] |
0.11[369] |
1.13[370] |
0.76[371] |
55 |
PIKFYVE |
1-phosphatidylinositol 3-phosphate 5-kinase |
[372] |
1.10[373] |
2.84[374] |
4.00[375] |
2.47[376] |
2.62[377] |
3.82[378] |
56 |
NCF1 |
Neutrophil cytosol factor 1 |
[379] |
-7.24[380] |
-9.21[381] |
[382] |
[383] |
-9.21[384] |
-2.33[385] |
57 |
GAB2 |
GRB2-associated-binding protein 2 |
[386] |
1.49[387] |
1.36[388] |
1.66[389] |
0.76[390] |
1.10[391] |
1.01[392] |
58 |
HCK |
Tyrosine-protein kinase HCK |
[393] |
-5.92[394] |
-6.01[395] |
[396] |
-5.43[397] |
-6.12[398] |
1.17[399] |
59 |
WASF1 |
Wiskott-Aldrich syndrome protein family member 1 |
[400] |
1.26[401] |
1.03[402] |
2.42[403] |
0.99[404] |
1.89[405] |
0.85[406] |
60 |
WASF3 |
Wiskott-Aldrich syndrome protein family member 3 |
[407] |
1.49[408] |
1.52[409] |
2.77[410] |
2.25[411] |
1.29[412] |
1.38[413] |
61 |
INPP5D |
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 |
[414] |
3.78[415] |
4.25[416] |
-5.89[417] |
-5.83[418] |
-2.63[419] |
1.74[420] |
62 |
PIP5K1C |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma |
[421] |
2.69[422] |
2.01[423] |
2.39[424] |
2.46[425] |
3.27[426] |
1.93[427] |
63 |
PTPRC |
Receptor-type tyrosine-protein phosphatase C |
[428] |
[429] |
[430] |
[431] |
0.21[432] |
-8.46[433] |
3.61[434] |
64 |
PLCG2 |
1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase gamma-2 |
-1.36[435] |
-7.01[436] |
0.48[437] |
-2.90[438] |
-1.50[439] |
3.18[440] |
65 |
FCGR2A |
Low affinity immunoglobulin gamma Fc region receptor II-a |
[441] |
-6.45[442] |
[443] |
-3.61[444] |
-2.72[445] |
-4.98[446] |
1.66[447] |
66 |
MYO10 |
Unconventional myosin-X |
[448] |
3.47[449] |
3.00[450] |
-3.72[451] |
3.61[452] |
4.53[453] |
4.48[454] |
67 |
WAS |
Wiskott-Aldrich syndrome protein |
[455] |
-5.79[456] |
-5.16[457] |
-1.67[458] |
-3.67[459] |
-4.47[460] |
0.05[461] |
68 |
PRKCE |
Protein kinase C epsilon type |
[462] |
0.57[463] |
-0.86[464] |
1.68[465] |
0.82[466] |
1.43[467] |
4.03[468] |
69 |
PIP5K1B |
Phosphatidylinositol 4-phosphate 5-kinase type-1 beta |
[469] |
0.36[470] |
2.86[471] |
2.43[472] |
-3.99[473] |
-5.33[474] |
-2.43[475] |
70 |
PLA2G6 |
85/88 kDa calcium-independent phospholipase A2 |
[476] |
-0.02[477] |
2.50[478] |
2.88[479] |
-0.32[480] |
-0.01[481] |
2.11[482] |
71 |
LAT |
Linker for activation of T-cells family member 1 |
[483] |
-1.52[484] |
0.10[485] |
-1.45[486] |
-1.53[487] |
-0.70[488] |
0.04[489] |
72 |
FCGR2B |
Low affinity immunoglobulin gamma Fc region receptor II-b |
[490] |
-8.15[491] |
[492] |
[493] |
[494] |
-8.80[495] |
3.86[496] |
73 |
VAV3 |
Guanine nucleotide exchange factor VAV3 |
[497] |
1.73[498] |
0.11[499] |
2.33[500] |
3.52[501] |
-2.21[502] |
1.81[503] |
74 |
PLA2G4B |
Cytosolic phospholipase A2 beta |
[504] |
-6.64[505] |
-7.56[506] |
-4.94[507] |
-4.81[508] |
-4.89[509] |
[510] |
75 |
VAV1 |
Proto-oncogene vav |
[511] |
-8.57[512] |
-3.66[513] |
-5.32[514] |
-6.25[515] |
-7.26[516] |
1.65[517] |
76 |
PIK3R3 |
Phosphatidylinositol 3-kinase regulatory subunit gamma |
[518] |
1.65[519] |
1.74[520] |
2.63[521] |
3.00[522] |
2.27[523] |
3.14[524] |
77 |
AKT3 |
RAC-gamma serine/threonine-protein kinase |
[525] |
-1.92[526] |
-4.39[527] |
-3.66[528] |
5.68[529] |
4.88[530] |
4.07[531] |
78 |
PIK3R5 |
Phosphoinositide 3-kinase regulatory subunit 5 |
[532] |
-7.24[533] |
[534] |
-2.48[535] |
-4.09[536] |
-3.49[537] |
2.80[538] |
79 |
FCGR1A |
High affinity immunoglobulin gamma Fc receptor I |
[539] |
[540] |
[541] |
[542] |
-7.08[543] |
[544] |
-0.06[545] |
80 |
DOCK2 |
Dedicator of cytokinesis protein 2 |
[546] |
-4.53[547] |
[548] |
-6.55[549] |
2.32[550] |
1.46[551] |
4.80[552] |
81 |
SYK |
Tyrosine-protein kinase SYK |
[553] |
-8.24[554] |
-2.28[555] |
-5.25[556] |
-0.07[557] |
-3.33[558] |
3.82[559] |
82 |
PRKCB |
Protein kinase C beta type |
[560] |
-6.89[561] |
-5.60[562] |
[563] |
2.32[564] |
-2.74[565] |
4.00[566] |
83 |
DNM1 |
Dynamin-1 |
[567] |
2.16[568] |
0.42[569] |
2.17[570] |
5.43[571] |
5.17[572] |
2.40[573] |
84 |
SCIN |
Adseverin |
[574] |
-3.84[575] |
-3.37[576] |
2.21[577] |
2.16[578] |
-1.78[579] |
-0.61[580] |
85 |
PLA2G4F |
Cytosolic phospholipase A2 zeta |
[581] |
-2.65[582] |
-1.11[583] |
-4.08[584] |
-5.11[585] |
-4.38[586] |
[587] |
86 |
PIK3CG |
Phosphatidylinositol
4,5-bisphosphate 3-kinase catalytic subunit gamma isoform |
[588] |
[589] |
[590] |
1.18[591] |
-3.46[592] |
4.56[593] |
87 |
PLA2G4D |
Cytosolic phospholipase A2 delta |
[594] |
2.93[595] |
1.32[596] |
0.73[597] |
-4.26[598] |
-3.10[599] |
[600] |
88 |
AMPH |
Amphiphysin |
[601] |
-4.77[602] |
-3.61[603] |
[604] |
2.92[605] |
5.36[606] |
2.10[607] |
89 |
PRKCG |
Protein kinase C gamma type |
[608] |
-0.90[609] |
-0.14[610] |
-2.47[611] |
-1.23[612] |
-1.06[613] |
[614] |
90 |
PLA2G4A |
Cytosolic phospholipase A2 |
[615] |
0.19[616] |
-2.27[617] |
5.88[618] |
3.34[619] |
7.35[620] |
4.82[621] |
91 |
PLA2G4E |
Cytosolic phospholipase A2 epsilon |
[622] |
2.93[623] |
3.36[624] |
4.03[625] |
3.12[626] |
3.19[627] |
1.58[628] |
92 |
DNM3 |
Dynamin-3 |
[629] |
-0.94[630] |
0.33[631] |
4.06[632] |
8.41[633] |
4.55[634] |
5.81[635] |
93 |
FCGR2C |
Low affinity immunoglobulin gamma Fc region receptor II-c |
[636] |
[637] |
[638] |
[639] |
[640] |
[641] |
[642] |
94 |
PLPP1 |
Phospholipid phosphatase 1 |
[643] |
[644] |
[645] |
[646] |
[647] |
[648] |
[649] |
95 |
PLPP2 |
Phospholipid phosphatase 2 |
[650] |
[651] |
[652] |
[653] |
[654] |
[655] |
[656] |
96 |
PLPP3 |
Phospholipid phosphatase 3 |
[657] |
[658] |
[659] |
[660] |
[661] |
[662] |
[663] |
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