KEGG_ENDOMETRIAL_CANCER | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | AKT1 | RAC-alpha serine/threonine-protein kinase | [1] | -0.93[2] | -0.81[3] | -2.15[4] | -0.61[5] | -0.48[6] | -0.88[7] |
2 | CTNNB1 | Catenin beta-1 | [8] | 0.61[9] | 0.46[10] | 1.09[11] | 0.20[12] | 0.53[13] | 0.48[14] |
3 | ILK | Integrin-linked protein kinase | [15] | -1.81[16] | -1.52[17] | -1.86[18] | -1.01[19] | -1.79[20] | -2.09[21] |
4 | CTNNA1 | Catenin alpha-1 | [22] | 0.44[23] | 0.29[24] | -0.43[25] | 0.80[26] | 0.54[27] | -0.01[28] |
5 | MYC | Myc proto-oncogene protein | [29] | -0.58[30] | -0.56[31] | -2.85[32] | -3.35[33] | -0.87[34] | -2.63[35] |
6 | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 | [36] | -1.94[37] | -1.91[38] | -1.59[39] | -1.10[40] | -0.48[41] | -1.82[42] |
7 | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2 | [43] | -0.95[44] | -0.92[45] | -0.32[46] | -1.40[47] | -0.81[48] | -2.33[49] |
8 | CCND1 | G1/S-specific cyclin-D1 | [50] | 2.04[51] | -0.11[52] | 0.46[53] | 1.32[54] | -0.05[55] | 0.42[56] |
9 | GRB2 | Growth factor receptor-bound protein 2 | [57] | 0.19[58] | 0.38[59] | 0.24[60] | 0.00[61] | 0.02[62] | -0.33[63] |
10 | BAD | Bcl2-associated agonist of cell death | [64] | -2.68[65] | -2.19[66] | -3.40[67] | -1.62[68] | -1.11[69] | -2.05[70] |
11 | RAF1 | RAF proto-oncogene serine/threonine-protein kinase | [71] | -1.07[72] | -0.31[73] | 0.69[74] | -0.74[75] | 0.23[76] | 0.47[77] |
12 | NRAS | GTPase NRas | [78] | -0.38[79] | 0.41[80] | 0.56[81] | 0.44[82] | 0.12[83] | -0.88[84] |
13 | ARAF | Serine/threonine-protein kinase A-Raf | [85] | -1.46[86] | -1.42[87] | -1.41[88] | -0.65[89] | -0.51[90] | 0.25[91] |
14 | CDH1 | Cadherin-1 | [92] | 0.11[93] | 0.95[94] | 1.21[95] | -3.73[96] | -7.87[97] | 0.93[98] |
15 | HRAS | GTPase HRas | [99] | -2.02[100] | -2.37[101] | -3.42[102] | -1.50[103] | -1.61[104] | -3.29[105] |
16 | MAPK1 | Mitogen-activated protein kinase 1 | [106] | 0.70[107] | 1.19[108] | 0.76[109] | 1.29[110] | 1.05[111] | 1.14[112] |
17 | AKT2 | RAC-beta serine/threonine-protein kinase | [113] | -0.05[114] | 0.58[115] | 0.45[116] | 0.30[117] | 0.20[118] | 0.50[119] |
18 | KRAS | GTPase KRas | [120] | -1.52[121] | -1.19[122] | 0.15[123] | 0.25[124] | 0.01[125] | 0.04[126] |
19 | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha | [127] | -1.48[128] | -1.01[129] | -0.18[130] | 1.51[131] | 1.12[132] | 2.37[133] |
20 | SOS1 | Son of sevenless homolog 1 | [134] | -1.11[135] | 0.78[136] | 0.02[137] | 0.29[138] | -0.37[139] | -0.09[140] |
21 | ELK1 | ETS domain-containing protein Elk-1 | [141] | -1.32[142] | -3.11[143] | -0.95[144] | -0.28[145] | 0.41[146] | -0.80[147] |
22 | PTEN | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protei | -1.55[148] | 0.20[149] | 0.14[150] | -1.12[151] | 0.24[152] | 1.85[153] | |
23 | MLH1 | DNA mismatch repair protein Mlh1 | [154] | -0.16[155] | 0.32[156] | 0.80[157] | -0.42[158] | 0.35[159] | -0.20[160] |
24 | ERBB2 | Receptor tyrosine-protein kinase erbB-2 | [161] | 1.36[162] | 0.54[163] | 1.45[164] | 0.70[165] | 0.41[166] | -0.48[167] |
25 | EGFR | Epidermal growth factor receptor | [168] | -1.71[169] | -1.72[170] | 0.89[171] | -0.12[172] | 0.60[173] | 2.02[174] |
26 | TP53 | Cellular tumor antigen p53 | [175] | 0.63[176] | 0.55[177] | 1.04[178] | 0.74[179] | 0.51[180] | -0.67[181] |
27 | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta | [182] | 0.87[183] | 1.44[184] | 1.79[185] | 0.15[186] | 0.82[187] | -0.92[188] |
28 | AXIN1 | Axin-1 | [189] | 0.34[190] | 1.01[191] | -0.81[192] | -9.25[193] | -0.30[194] | -1.28[195] |
29 | MAPK3 | Mitogen-activated protein kinase 3 | [196] | 0.84[197] | 1.24[198] | 1.02[199] | -0.13[200] | 0.00[201] | -1.67[202] |
30 | GSK3B | Glycogen synthase kinase-3 beta | [203] | 0.26[204] | 0.25[205] | 0.56[206] | 1.26[207] | 1.19[208] | 0.53[209] |
31 | AXIN2 | Axin-2 | [210] | 2.46[211] | 0.42[212] | -3.89[213] | -1.65[214] | -1.91[215] | -2.97[216] |
32 | PDPK1 | 3-phosphoinositide-dependent protein kinase 1 | [217] | 1.32[218] | 2.87[219] | 1.32[220] | 0.88[221] | 1.38[222] | 1.87[223] |
33 | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 0.20[224] | 1.06[225] | 0.96[226] | 0.49[227] | 0.76[228] | 0.53[229] | |
34 | FOXO3 | Forkhead box protein O3 | [230] | -0.55[231] | -0.11[232] | 0.27[233] | -0.16[234] | 1.19[235] | 1.70[236] |
35 | CASP9 | Caspase-9 | [237] | -0.85[238] | 0.46[239] | -0.68[240] | -0.31[241] | -0.89[242] | -1.17[243] |
36 | SOS2 | Son of sevenless homolog 2 | [244] | -1.03[245] | 0.45[246] | -0.59[247] | 1.13[248] | 1.10[249] | 1.21[250] |
37 | TCF7L2 | Transcription factor 7-like 2 | [251] | -0.14[252] | 0.98[253] | 0.92[254] | 0.14[255] | 0.23[256] | 1.09[257] |
38 | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | -1.39[258] | 0.60[259] | 0.53[260] | 0.57[261] | 0.88[262] | 1.28[263] | |
39 | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 0.88[264] | 2.32[265] | -1.76[266] | -0.28[267] | 0.60[268] | -0.33[269] | |
40 | TCF7L1 | Transcription factor 7-like 1 | [270] | -4.06[271] | -1.90[272] | 0.03[273] | -2.38[274] | -2.15[275] | -0.34[276] |
41 | TCF7 | Transcription factor 7 | [277] | 1.43[278] | 0.44[279] | -0.77[280] | -0.39[281] | -0.59[282] | -1.00[283] |
42 | APC | Adenomatous polyposis coli protein | [284] | -0.44[285] | 1.59[286] | 1.16[287] | 1.67[288] | 2.41[289] | 3.11[290] |
43 | BRAF | Serine/threonine-protein kinase B-raf | [291] | -0.76[292] | -0.68[293] | 1.09[294] | 0.18[295] | -0.01[296] | 1.22[297] |
44 | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma | [298] | 0.71[299] | 1.08[300] | 1.66[301] | 2.61[302] | 1.74[303] | 2.05[304] |
45 | AKT3 | RAC-gamma serine/threonine-protein kinase | [305] | -2.85[306] | -5.06[307] | -4.63[308] | 5.29[309] | 4.35[310] | 2.98[311] |
46 | PIK3R5 | Phosphoinositide 3-kinase regulatory subunit 5 | [312] | -8.18[313] | [314] | -3.45[315] | -4.48[316] | -4.03[317] | 1.71[318] |
47 | CTNNA3 | Catenin alpha-3 | [319] | -6.23[320] | [321] | [322] | -5.82[323] | -5.09[324] | 2.40[325] |
48 | PIK3CG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | [326] | [327] | [328] | 0.78[329] | -3.99[330] | 3.47[331] | |
49 | LEF1 | Lymphoid enhancer-binding factor 1 | [332] | 1.64[333] | -4.93[334] | 2.73[335] | 0.53[336] | -1.07[337] | 0.45[338] |
50 | APC2 | Adenomatous polyposis coli protein 2 | [339] | 2.61[340] | 2.98[341] | 2.72[342] | 2.31[343] | 2.45[344] | 3.79[345] |
51 | CTNNA2 | Catenin alpha-2 | [346] | -0.21[347] | -2.81[348] | -4.19[349] | [350] | -3.38[351] | -0.86[352] |
52 | EGF | Pro-epidermal growth factor | [353] | 0.96[354] | 3.10[355] | 6.45[356] | 8.47[357] | 6.00[358] | 0.95[359] |