KEGG_DORSO_VENTRAL_AXIS_FORMATION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 ETS2 Protein C-ets-2 [1] -0.56[2] -1.06[3] -3.19[4] -2.76[5] -2.53[6] -0.75[7]
2 MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 [8] -1.27[9] -1.61[10] -1.25[11] -1.30[12] -0.83[13] -2.14[14]
3 GRB2 Growth factor receptor-bound protein 2 [15] 0.85[16] 0.68[17] 0.58[18] -0.20[19] -0.32[20] -0.65[21]
4 ETS1 Protein C-ets-1 [22] -3.15[23] -12.50[24] -9.92[25] -0.85[26] -0.03[27] -1.04[28]
5 MAPK1 Mitogen-activated protein kinase 1 [29] 1.36[30] 1.49[31] 1.10[32] 1.09[33] 0.71[34] 0.83[35]
6 KRAS GTPase KRas [36] -0.86[37] -0.89[38] 0.49[39] 0.04[40] -0.33[41] -0.28[42]
7 SOS1 Son of sevenless homolog 1 [43] -0.45[44] 1.07[45] 0.36[46] 0.09[47] -0.71[48] -0.41[49]
8 EGFR Epidermal growth factor receptor [50] -1.04[51] -1.43[52] 1.24[53] -0.32[54] 0.26[55] 1.70[56]
9 NOTCH2 Neurogenic locus notch homolog protein 2 [57] -0.21[58] -5.96[59] 1.31[60] 2.28[61] 3.04[62] 2.38[63]
10 MAPK3 Mitogen-activated protein kinase 3 [64] 1.50[65] 1.54[66] 1.36[67] -0.33[68] -0.35[69] -1.99[70]
11 SPIRE1 Protein spire homolog 1 [71] 1.25[72] 1.35[73] 0.27[74] 0.75[75] 0.86[76] -0.63[77]
12 SOS2 Son of sevenless homolog 2 [78] -0.37[79] 0.74[80] -0.24[81] 0.93[82] 0.76[83] 0.89[84]
13 SPIRE2 Protein spire homolog 2 [85] 0.31[86] 2.37[87] 1.75[88] -0.75[89] -2.67[90] -1.81[91]
14 ETV6 Transcription factor ETV6 [92] -0.02[93] 0.03[94] -0.05[95] 0.91[96] 0.46[97] 0.64[98]
15 NOTCH1 Neurogenic locus notch homolog protein 1 [99] 1.56[100] 0.39[101] 1.51[102] 1.83[103] 2.15[104] 3.69[105]
16 PIWIL2 Piwi-like protein 2 [106] -1.47[107] 1.17[108] 1.10[109] -1.58[110] -2.16[111] 0.08[112]
17 ETV7 Transcription factor ETV7 [113] -2.23[114] [115] -2.94[116] -0.64[117] -0.98[118] -0.73[119]
18 NOTCH3 Neurogenic locus notch homolog protein 3 [120] 3.72[121] -0.65[122] 5.10[123] 5.49[124] 3.30[125] 3.13[126]
19 NOTCH4 Neurogenic locus notch homolog protein 4 [127] 0.22[128] 0.78[129] -2.08[130] -2.77[131] -0.19[132] 5.26[133]
20 PIWIL1 Piwi-like protein 1 [134] [135] [136] [137] [138] [139] [140]
21 CPEB1 Cytoplasmic polyadenylation element-binding protein 1 [141] 1.42[142] -1.38[143] -3.33[144] 6.10[145] 4.50[146] 2.97[147]
22 PIWIL4 Piwi-like protein 4 [148] -4.83[149] -3.49[150] -4.83[151] 2.68[152] 1.30[153] 2.74[154]
23 PIWIL3 Piwi-like protein 3 [155] -0.73[156] 1.29[157] -1.24[158] -1.38[159] -0.86[160] -0.21[161]
24 FMN2 Formin-2 [162] [163] [164] [165] [166] [167] [168]
[1]
ref_hepatocyte ETS2
Mean 37.2
Standard deviation 18
Values 19 35 49 62 21
[2]
HepG2 ETS2
Mean 71
Standard deviation 26
Values 89 53
[3]
HepG2.C3A ETS2
Mean 44.9
Standard deviation 14
Values 55 35
[4]
HuH.7 ETS2
Mean 11.5
Standard deviation 2.9
Values 9.9 15 9.7
[5]
SNU475 ETS2
Mean 17
Standard deviation 2.5
Values 19 15
[6]
THLE ETS2
Mean 23
Standard deviation 6
Values 19 27
[7]
liver ETS2
Mean 60.5
Standard deviation 11
Values 47 70 56 69
[8]
ref_hepatocyte MAP2K1
Mean 28.1
Standard deviation 8.6
Values 27 39 15 32 27
[9]
HepG2 MAP2K1
Mean 32.6
Standard deviation 3.7
Values 35 30
[10]
HepG2.C3A MAP2K1
Mean 23.1
Standard deviation 0.39
Values 23 23
[11]
HuH.7 MAP2K1
Mean 33.2
Standard deviation 6.4
Values 33 27 40
[12]
SNU475 MAP2K1
Mean 35.5
Standard deviation 5.2
Values 32 39
[13]
THLE MAP2K1
Mean 56.5
Standard deviation 3.6
Values 54 59
[14]
liver MAP2K1
Mean 17.5
Standard deviation 8
Values 11 28 18 12
[15]
ref_hepatocyte GRB2
Mean 20.7
Standard deviation 5.5
Values 27 26 14 20 17
[16]
HepG2 GRB2
Mean 104
Standard deviation 4.7
Values 1e+02 1.1e+02
[17]
HepG2.C3A GRB2
Mean 83.1
Standard deviation 0.44
Values 83 83
[18]
HuH.7 GRB2
Mean 86.7
Standard deviation 7.6
Values 89 78 93
[19]
SNU475 GRB2
Mean 55.7
Standard deviation 1.4
Values 55 57
[20]
THLE GRB2
Mean 58.8
Standard deviation 3.7
Values 56 61
[21]
liver GRB2
Mean 36.1
Standard deviation 16
Values 22 50 50 22
[22]
ref_hepatocyte ETS1
Mean 11.2
Standard deviation 17
Values 0.38 40 0.61 13 2
[23]
HepG2 ETS1
Mean 3.55
Standard deviation 2
Values 5 2.1
[24]
HepG2.C3A ETS1
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[25]
HuH.7 ETS1
Mean 0.0324
Standard deviation 0.021
Values 0.049 0.039 0.0094
[26]
SNU475 ETS1
Mean 19.3
Standard deviation 8
Values 14 25
[27]
THLE ETS1
Mean 39
Standard deviation 5.5
Values 35 43
[28]
liver ETS1
Mean 15
Standard deviation 7.2
Values 24 10 8.1 18
[29]
ref_hepatocyte MAPK1
Mean 10.7
Standard deviation 3.7
Values 14 13 6.1 13 7.4
[30]
HepG2 MAPK1
Mean 77.6
Standard deviation 22
Values 62 93
[31]
HepG2.C3A MAPK1
Mean 76.1
Standard deviation 7.2
Values 71 81
[32]
HuH.7 MAPK1
Mean 64.8
Standard deviation 7.4
Values 73 60 61
[33]
SNU475 MAPK1
Mean 71.1
Standard deviation 8
Values 77 65
[34]
THLE MAPK1
Mean 62.4
Standard deviation 14
Values 53 72
[35]
liver MAPK1
Mean 52.3
Standard deviation 14
Values 68 39 41 61
[36]
ref_hepatocyte KRAS
Mean 8.97
Standard deviation 7.9
Values 18 17 1.7 5.4 2.7
[37]
HepG2 KRAS
Mean 13.9
Standard deviation 3.1
Values 12 16
[38]
HepG2.C3A KRAS
Mean 12.2
Standard deviation 2.3
Values 11 14
[39]
HuH.7 KRAS
Mean 35.4
Standard deviation 4.8
Values 40 30 36
[40]
SNU475 KRAS
Mean 28.7
Standard deviation 5.5
Values 33 25
[41]
THLE KRAS
Mean 25.4
Standard deviation 1.5
Values 24 26
[42]
liver KRAS
Mean 20.4
Standard deviation 8.7
Values 16 33 19 14
[43]
ref_hepatocyte SOS1
Mean 6.81
Standard deviation 11
Values 27 1.9 1.3 2.2 1.5
[44]
HepG2 SOS1
Mean 14
Standard deviation 6.5
Values 9.4 19
[45]
HepG2.C3A SOS1
Mean 36.1
Standard deviation 3.7
Values 39 33
[46]
HuH.7 SOS1
Mean 24.6
Standard deviation 11
Values 22 37 15
[47]
SNU475 SOS1
Mean 22.5
Standard deviation 3.3
Values 25 20
[48]
THLE SOS1
Mean 14.8
Standard deviation 1.4
Values 16 14
[49]
liver SOS1
Mean 14.1
Standard deviation 3.8
Values 18 13 9.3 16
[50]
ref_hepatocyte EGFR
Mean 5.53
Standard deviation 4.2
Values 0.94 8.5 3.5 11 3.5
[51]
HepG2 EGFR
Mean 7.53
Standard deviation 0.89
Values 6.9 8.2
[52]
HepG2.C3A EGFR
Mean 5.18
Standard deviation 0.67
Values 5.7 4.7
[53]
HuH.7 EGFR
Mean 36.6
Standard deviation 25
Values 32 63 15
[54]
SNU475 EGFR
Mean 13.7
Standard deviation 0.74
Values 13 14
[55]
THLE EGFR
Mean 23.6
Standard deviation 4.4
Values 20 27
[56]
liver EGFR
Mean 49.4
Standard deviation 14
Values 69 39 47 42
[57]
ref_hepatocyte NOTCH2
Mean 5.26
Standard deviation 4
Values 1.6 11 2.4 7.1 3.7
[58]
HepG2 NOTCH2
Mean 12.7
Standard deviation 3.4
Values 15 10
[59]
HepG2.C3A NOTCH2
Mean 0.213
Standard deviation 0.12
Values 0.13 0.3
[60]
HuH.7 NOTCH2
Mean 36.5
Standard deviation 12
Values 44 43 23
[61]
SNU475 NOTCH2
Mean 79.3
Standard deviation 13
Values 88 70
[62]
THLE NOTCH2
Mean 154
Standard deviation 35
Values 1.3e+02 1.8e+02
[63]
liver NOTCH2
Mean 74.9
Standard deviation 42
Values 1.2e+02 39 39 99
[64]
ref_hepatocyte MAPK3
Mean 4.16
Standard deviation 1.3
Values 5.1 2.8 6 3.6 3.3
[65]
HepG2 MAPK3
Mean 33.1
Standard deviation 5.2
Values 37 29
[66]
HepG2.C3A MAPK3
Mean 30.4
Standard deviation 12
Values 39 22
[67]
HuH.7 MAPK3
Mean 30
Standard deviation 4.8
Values 34 25 32
[68]
SNU475 MAPK3
Mean 10.2
Standard deviation 2.4
Values 12 8.5
[69]
THLE MAPK3
Mean 11.6
Standard deviation 1.1
Values 11 12
[70]
liver MAPK3
Mean 2.87
Standard deviation 2.4
Values 0.81 5 4.8 0.82
[71]
ref_hepatocyte SPIRE1
Mean 3.02
Standard deviation 3.1
Values 7.8 4.3 0.79 2 0.27
[72]
HepG2 SPIRE1
Mean 20.2
Standard deviation 0.64
Values 20 21
[73]
HepG2.C3A SPIRE1
Mean 19.3
Standard deviation 5.7
Values 23 15
[74]
HuH.7 SPIRE1
Mean 10.2
Standard deviation 2.7
Values 8.9 13 8.3
[75]
SNU475 SPIRE1
Mean 15.7
Standard deviation 1.3
Values 17 15
[76]
THLE SPIRE1
Mean 19.5
Standard deviation 1.1
Values 19 20
[77]
liver SPIRE1
Mean 5.34
Standard deviation 5.4
Values 13 1.1 4.9 2.3
[78]
ref_hepatocyte SOS2
Mean 2.58
Standard deviation 0.97
Values 4 2.6 1.5 2.8 1.9
[79]
HepG2 SOS2
Mean 5.6
Standard deviation 3
Values 3.5 7.7
[80]
HepG2.C3A SOS2
Mean 10.9
Standard deviation 0.059
Values 11 11
[81]
HuH.7 SOS2
Mean 6.11
Standard deviation 1.7
Values 6.5 7.5 4.3
[82]
SNU475 SOS2
Mean 15.3
Standard deviation 6
Values 19 11
[83]
THLE SOS2
Mean 15.6
Standard deviation 2.6
Values 17 14
[84]
liver SOS2
Mean 13.1
Standard deviation 7.3
Values 19 7.4 6.2 20
[85]
ref_hepatocyte SPIRE2
Mean 1.99
Standard deviation 2.4
Values 6.2 0.73 1.4 0.29 1.2
[86]
HepG2 SPIRE2
Mean 6.91
Standard deviation 1.7
Values 8.1 5.7
[87]
HepG2.C3A SPIRE2
Mean 25.8
Standard deviation 17
Values 38 14
[88]
HuH.7 SPIRE2
Mean 18.8
Standard deviation 1.6
Values 17 19 20
[89]
SNU475 SPIRE2
Mean 3.67
Standard deviation 1.1
Values 4.5 2.9
[90]
THLE SPIRE2
Mean 1.11
Standard deviation 0.2
Values 1.3 0.97
[91]
liver SPIRE2
Mean 1.56
Standard deviation 0.42
Values 1.9 1.8 0.98 1.5
[92]
ref_hepatocyte ETV6
Mean 1.23
Standard deviation 0.82
Values 0.7 0.22 2.4 1.6 1.3
[93]
HepG2 ETV6
Mean 3.42
Standard deviation 0.44
Values 3.7 3.1
[94]
HepG2.C3A ETV6
Mean 3.16
Standard deviation 0.23
Values 3.3 3
[95]
HuH.7 ETV6
Mean 3.34
Standard deviation 0.2
Values 3.2 3.6 3.3
[96]
SNU475 ETV6
Mean 7.17
Standard deviation 0.95
Values 6.5 7.8
[97]
THLE ETV6
Mean 6.06
Standard deviation 0.68
Values 6.5 5.6
[98]
liver ETV6
Mean 5.28
Standard deviation 1.4
Values 5.3 5.8 3.4 6.6
[99]
ref_hepatocyte NOTCH1
Mean 0.644
Standard deviation 0.25
Values 0.33 0.55 0.91 0.55 0.89
[100]
HepG2 NOTCH1
Mean 5.33
Standard deviation 3.7
Values 8 2.7
[101]
HepG2.C3A NOTCH1
Mean 2.12
Standard deviation 0.1
Values 2.1 2.2
[102]
HuH.7 NOTCH1
Mean 5.14
Standard deviation 1.4
Values 5.4 6.4 3.6
[103]
SNU475 NOTCH1
Mean 7.09
Standard deviation 0.64
Values 6.6 7.5
[104]
THLE NOTCH1
Mean 10.2
Standard deviation 2.2
Values 8.6 12
[105]
liver NOTCH1
Mean 22.8
Standard deviation 16
Values 31 10 8.8 41
[106]
ref_hepatocyte PIWIL2
Mean 0.298
Standard deviation 0.13
Values 0.43 0.27 0.44 0.15 0.2
[107]
HepG2 PIWIL2
Mean 0.302
Standard deviation 0.075
Values 0.36 0.25
[108]
HepG2.C3A PIWIL2
Mean 1.69
Standard deviation 0.12
Values 1.6 1.8
[109]
HuH.7 PIWIL2
Mean 1.79
Standard deviation 1
Values 1.4 3 1
[110]
SNU475 PIWIL2
Mean 0.311
Standard deviation 0.026
Values 0.29 0.33
[111]
THLE PIWIL2
Mean 0.237
Standard deviation 0.057
Values 0.28 0.2
[112]
liver PIWIL2
Mean 0.865
Standard deviation 0.33
Values 0.91 0.92 0.41 1.2
[113]
ref_hepatocyte ETV7
Mean 0.228
Standard deviation 0.31
Values 0 0 0.59 0 0.54
[114]
HepG2 ETV7
Mean 0.136
Standard deviation 0.11
Values 0.21 0.06
[115]
HepG2.C3A ETV7
Mean 0
Standard deviation 0
Values 0 0
[116]
HuH.7 ETV7
Mean 0.0833
Standard deviation 0.035
Values 0.12 0.071 0.056
[117]
SNU475 ETV7
Mean 0.454
Standard deviation 0.27
Values 0.64 0.26
[118]
THLE ETV7
Mean 0.413
Standard deviation 0.027
Values 0.43 0.39
[119]
liver ETV7
Mean 0.376
Standard deviation 0.38
Values 0.19 0.33 0.92 0.066
[120]
ref_hepatocyte NOTCH3
Mean 0.138
Standard deviation 0.22
Values 0.028 0.028 0.043 0.54 0.057
[121]
HepG2 NOTCH3
Mean 5.12
Standard deviation 6.5
Values 9.7 0.55
[122]
HepG2.C3A NOTCH3
Mean 0.222
Standard deviation 0.057
Values 0.26 0.18
[123]
HuH.7 NOTCH3
Mean 13.3
Standard deviation 4.1
Values 18 9.9 12
[124]
SNU475 NOTCH3
Mean 19.3
Standard deviation 5.2
Values 23 16
[125]
THLE NOTCH3
Mean 4.85
Standard deviation 2.7
Values 6.7 3
[126]
liver NOTCH3
Mean 3.33
Standard deviation 2.3
Values 4.1 2 1.1 6.2
[127]
ref_hepatocyte NOTCH4
Mean 0.117
Standard deviation 0.16
Values 0 0 0.18 0.03 0.37
[128]
HepG2 NOTCH4
Mean 0.383
Standard deviation 0.29
Values 0.59 0.18
[129]
HepG2.C3A NOTCH4
Mean 0.505
Standard deviation 0.14
Values 0.6 0.41
[130]
HuH.7 NOTCH4
Mean 0.0776
Standard deviation 0.023
Values 0.074 0.1 0.056
[131]
SNU475 NOTCH4
Mean 0.0534
Standard deviation 0.0034
Values 0.051 0.056
[132]
THLE NOTCH4
Mean 0.365
Standard deviation 0.019
Values 0.38 0.35
[133]
liver NOTCH4
Mean 12.3
Standard deviation 1.6
Values 11 13 11 14
[134]
ref_hepatocyte PIWIL1
Mean 0.0301
Standard deviation 0.042
Values 0 0.085 0 0 0.065
[135]
HepG2 PIWIL1
Missing
[136]
HepG2.C3A PIWIL1
Missing
[137]
HuH.7 PIWIL1
Missing
[138]
SNU475 PIWIL1
Missing
[139]
THLE PIWIL1
Missing
[140]
liver PIWIL1
Missing
[141]
ref_hepatocyte CPEB1
Mean 0.0273
Standard deviation 0.049
Values 0.11 0.023 0 0 0
[142]
HepG2 CPEB1
Mean 0.205
Standard deviation 0.055
Values 0.17 0.24
[143]
HepG2.C3A CPEB1
Mean 0.0263
Standard deviation 0.023
Values 0.0097 0.043
[144]
HuH.7 CPEB1
Mean 0.00761
Standard deviation 0.0083
Values 0.016 0.0064 0
[145]
SNU475 CPEB1
Mean 5.81
Standard deviation 0.77
Values 5.3 6.4
[146]
THLE CPEB1
Mean 2.2
Standard deviation 0.47
Values 2.5 1.9
[147]
liver CPEB1
Mean 0.587
Standard deviation 0.44
Values 0.74 0.071 0.44 1.1
[148]
ref_hepatocyte PIWIL4
Mean 0.0217
Standard deviation 0.03
Values 0 0 0.052 0 0.057
[149]
HepG2 PIWIL4
Mean 0.00214
Standard deviation 0.003
Values 0 0.0043
[150]
HepG2.C3A PIWIL4
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[151]
HuH.7 PIWIL4
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[152]
SNU475 PIWIL4
Mean 0.432
Standard deviation 0.045
Values 0.46 0.4
[153]
THLE PIWIL4
Mean 0.19
Standard deviation 0.15
Values 0.3 0.085
[154]
liver PIWIL4
Mean 0.399
Standard deviation 0.21
Values 0.63 0.26 0.18 0.53
[155]
ref_hepatocyte PIWIL3
Mean 0.0207
Standard deviation 0.02
Values 0.031 0 0.043 0.03 0
[156]
HepG2 PIWIL3
Mean 0.035
Standard deviation 0.041
Values 0.0057 0.064
[157]
HepG2.C3A PIWIL3
Mean 0.128
Standard deviation 0.016
Values 0.12 0.14
[158]
HuH.7 PIWIL3
Mean 0.0246
Standard deviation 0.01
Values 0.033 0.013 0.028
[159]
SNU475 PIWIL3
Mean 0.0247
Standard deviation 0.015
Values 0.014 0.035
[160]
THLE PIWIL3
Mean 0.0405
Standard deviation 0.035
Values 0.065 0.016
[161]
liver PIWIL3
Mean 0.0491
Standard deviation 0.022
Values 0.043 0.024 0.077 0.053
[162]
ref_hepatocyte FMN2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[163]
HepG2 FMN2
Mean 0.0186
Standard deviation 0.014
Values 0.029 0.0086
[164]
HepG2.C3A FMN2
Mean 0.0107
Standard deviation 0.015
Values 0 0.021
[165]
HuH.7 FMN2
Mean 0.191
Standard deviation 0.2
Values 0.09 0.42 0.066
[166]
SNU475 FMN2
Mean 34.1
Standard deviation 4
Values 37 31
[167]
THLE FMN2
Mean 0.927
Standard deviation 0.37
Values 0.67 1.2
[168]
liver FMN2
Mean 0.0256
Standard deviation 0.018
Values 0.014 0.024 0.051 0.013