KEGG_CIRCADIAN_RHYTHM_MAMMAL Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 BHLHE40 Class E basic helix-loop-helix protein 40 [1] -0.35[2] -0.25[3] -1.10[4] -1.53[5] -1.21[6] -1.59[7]
2 CSNK1D Casein kinase I isoform delta [8] 0.69[9] 0.34[10] 0.22[11] 0.90[12] 0.24[13] -1.11[14]
3 NR1D1 Nuclear receptor subfamily 1 group D member 1 [15] -1.76[16] -2.20[17] -1.72[18] -1.24[19] -2.03[20] -1.47[21]
4 CSNK1E Casein kinase I isoform epsilon [22] 0.88[23] 0.40[24] 1.02[25] 0.34[26] 1.22[27] -1.34[28]
5 ARNTL Aryl hydrocarbon receptor nuclear translocator-like protein 1 [29] -2.56[30] -2.16[31] -3.16[32] -1.17[33] -1.18[34] 0.27[35]
6 CRY1 Cryptochrome-1 [36] -0.77[37] -0.18[38] -0.32[39] 0.22[40] -0.36[41] -0.45[42]
7 CRY2 Cryptochrome-2 [43] -0.40[44] -0.47[45] 1.07[46] -2.11[47] -1.50[48] 1.90[49]
8 PER1 Period circadian protein homolog 1 [50] -2.12[51] -1.42[52] 0.09[53] -1.65[54] 1.40[55] 1.35[56]
9 NPAS2 Neuronal PAS domain-containing protein 2 [57] 1.10[58] 1.66[59] 1.21[60] -2.50[61] -0.47[62] -0.70[63]
10 CLOCK Circadian locomoter output cycles protein kaput [64] 0.30[65] 1.40[66] 1.11[67] 2.21[68] 2.65[69] 2.91[70]
11 PER3 Period circadian protein homolog 3 [71] -0.89[72] -0.63[73] -1.99[74] 2.15[75] -1.14[76] 2.48[77]
12 PER2 Period circadian protein homolog 2 [78] 1.22[79] 1.27[80] 2.61[81] 0.26[82] -0.30[83] 1.95[84]
13 BHLHE41 Class E basic helix-loop-helix protein 41 [85] 0.76[86] -4.67[87] -0.90[88] 5.54[89] 3.42[90] -0.79[91]
[1]
ref_hepatocyte BHLHE40
Mean 27.1
Standard deviation 24
Values 3.2 19 35 65 13
[2]
HepG2 BHLHE40
Mean 65.3
Standard deviation 35
Values 90 40
[3]
HepG2.C3A BHLHE40
Mean 67.5
Standard deviation 32
Values 90 45
[4]
HuH.7 BHLHE40
Mean 36.9
Standard deviation 18
Values 28 58 24
[5]
SNU475 BHLHE40
Mean 18.8
Standard deviation 4.6
Values 16 22
[6]
THLE BHLHE40
Mean 29.9
Standard deviation 5.7
Values 26 34
[7]
liver BHLHE40
Mean 18.2
Standard deviation 6
Values 11 23 23 16
[8]
ref_hepatocyte CSNK1D
Mean 18
Standard deviation 10
Values 31 25 13 14 6.5
[9]
HepG2 CSNK1D
Mean 89.7
Standard deviation 12
Values 98 81
[10]
HepG2.C3A CSNK1D
Mean 67.9
Standard deviation 18
Values 81 55
[11]
HuH.7 CSNK1D
Mean 61.3
Standard deviation 2.1
Values 60 60 64
[12]
SNU475 CSNK1D
Mean 67.2
Standard deviation 23
Values 84 51
[13]
THLE CSNK1D
Mean 54.7
Standard deviation 1
Values 54 55
[14]
liver CSNK1D
Mean 17
Standard deviation 6.7
Values 10 24 21 13
[15]
ref_hepatocyte NR1D1
Mean 6.83
Standard deviation 12
Values 0.3 0.38 3.3 28 1.9
[16]
HepG2 NR1D1
Mean 6.24
Standard deviation 3.5
Values 8.7 3.7
[17]
HepG2.C3A NR1D1
Mean 4.42
Standard deviation 2.4
Values 6.1 2.7
[18]
HuH.7 NR1D1
Mean 6.06
Standard deviation 2.4
Values 5.6 8.7 4
[19]
SNU475 NR1D1
Mean 5.79
Standard deviation 1.3
Values 4.9 6.7
[20]
THLE NR1D1
Mean 4.28
Standard deviation 0.22
Values 4.1 4.4
[21]
liver NR1D1
Mean 4.99
Standard deviation 4
Values 2.1 9.9 6.7 1.3
[22]
ref_hepatocyte CSNK1E
Mean 6.27
Standard deviation 5.9
Values 6.5 5.5 1.9 16 1.4
[23]
HepG2 CSNK1E
Mean 35.7
Standard deviation 14
Values 45 26
[24]
HepG2.C3A CSNK1E
Mean 24.6
Standard deviation 8.9
Values 31 18
[25]
HuH.7 CSNK1E
Mean 37.3
Standard deviation 3.1
Values 34 37 40
[26]
SNU475 CSNK1E
Mean 15.9
Standard deviation 1.1
Values 17 15
[27]
THLE CSNK1E
Mean 37.4
Standard deviation 4.6
Values 34 41
[28]
liver CSNK1E
Mean 5.04
Standard deviation 1.3
Values 4.4 6 3.6 6.1
[29]
ref_hepatocyte ARNTL
Mean 5.32
Standard deviation 2.6
Values 1.3 5.3 7.9 4.6 7.5
[30]
HepG2 ARNTL
Mean 2.79
Standard deviation 0.22
Values 2.6 2.9
[31]
HepG2.C3A ARNTL
Mean 3.53
Standard deviation 0.11
Values 3.6 3.5
[32]
HuH.7 ARNTL
Mean 1.74
Standard deviation 0.12
Values 1.6 1.8 1.8
[33]
SNU475 ARNTL
Mean 4.73
Standard deviation 0.49
Values 4.4 5.1
[34]
THLE ARNTL
Mean 6.03
Standard deviation 0.14
Values 5.9 6.1
[35]
liver ARNTL
Mean 13.1
Standard deviation 2.3
Values 12 12 17 12
[36]
ref_hepatocyte CRY1
Mean 5.06
Standard deviation 3.6
Values 5.6 11 3.7 2.7 2.3
[37]
HepG2 CRY1
Mean 9.13
Standard deviation 1.8
Values 7.9 10
[38]
HepG2.C3A CRY1
Mean 13.2
Standard deviation 2.9
Values 15 11
[39]
HuH.7 CRY1
Mean 11.8
Standard deviation 2.2
Values 12 9.4 14
[40]
SNU475 CRY1
Mean 11.8
Standard deviation 1.6
Values 11 13
[41]
THLE CRY1
Mean 10.1
Standard deviation 0.86
Values 9.5 11
[42]
liver CRY1
Mean 7.49
Standard deviation 2.3
Values 4.4 9.4 8.9 7.4
[43]
ref_hepatocyte CRY2
Mean 4.47
Standard deviation 3.7
Values 1.8 1.1 9 2.6 7.8
[44]
HepG2 CRY2
Mean 10.4
Standard deviation 1.9
Values 9 12
[45]
HepG2.C3A CRY2
Mean 9.56
Standard deviation 2.5
Values 11 7.8
[46]
HuH.7 CRY2
Mean 27.3
Standard deviation 2.5
Values 27 30 25
[47]
SNU475 CRY2
Mean 2.08
Standard deviation 0.19
Values 1.9 2.2
[48]
THLE CRY2
Mean 4.04
Standard deviation 0.12
Values 4 4.1
[49]
liver CRY2
Mean 33.9
Standard deviation 4.4
Values 31 38 29 37
[50]
ref_hepatocyte PER1
Mean 4.3
Standard deviation 3.7
Values 0.52 1.1 8.6 7.4 3.8
[51]
HepG2 PER1
Mean 3.06
Standard deviation 0.013
Values 3 3.1
[52]
HepG2.C3A PER1
Mean 4.75
Standard deviation 1.9
Values 6.1 3.4
[53]
HuH.7 PER1
Mean 13.3
Standard deviation 2
Values 14 15 11
[54]
SNU475 PER1
Mean 2.75
Standard deviation 0.75
Values 3.3 2.2
[55]
THLE PER1
Mean 29.1
Standard deviation 0.82
Values 29 30
[56]
liver PER1
Mean 22.3
Standard deviation 13
Values 8.3 40 17 24
[57]
ref_hepatocyte NPAS2
Mean 3.6
Standard deviation 1.4
Values 3.9 2 5.7 3.5 2.9
[58]
HepG2 NPAS2
Mean 23.8
Standard deviation 0.38
Values 24 24
[59]
HepG2.C3A NPAS2
Mean 33.8
Standard deviation 11
Values 42 26
[60]
HuH.7 NPAS2
Mean 24.3
Standard deviation 6.4
Values 30 17 26
[61]
SNU475 NPAS2
Mean 1.27
Standard deviation 1.1
Values 0.47 2.1
[62]
THLE NPAS2
Mean 6.67
Standard deviation 0.73
Values 7.2 6.1
[63]
liver NPAS2
Mean 4.49
Standard deviation 1.6
Values 3.8 5 6.4 2.7
[64]
ref_hepatocyte CLOCK
Mean 1.77
Standard deviation 1.8
Values 1.2 4.8 0.53 2.2 0.24
[65]
HepG2 CLOCK
Mean 6.74
Standard deviation 3.1
Values 4.6 8.9
[66]
HepG2.C3A CLOCK
Mean 13.9
Standard deviation 3.4
Values 11 16
[67]
HuH.7 CLOCK
Mean 11.2
Standard deviation 3.9
Values 12 15 7.1
[68]
SNU475 CLOCK
Mean 16.5
Standard deviation 0.94
Values 16 17
[69]
THLE CLOCK
Mean 28.4
Standard deviation 2.1
Values 30 27
[70]
liver CLOCK
Mean 27.1
Standard deviation 6.8
Values 31 24 19 34
[71]
ref_hepatocyte PER3
Mean 1.02
Standard deviation 0.97
Values 0.45 0.41 0.68 0.85 2.7
[72]
HepG2 PER3
Mean 1.71
Standard deviation 0.19
Values 1.6 1.8
[73]
HepG2.C3A PER3
Mean 1.96
Standard deviation 0.5
Values 2.3 1.6
[74]
HuH.7 PER3
Mean 0.753
Standard deviation 0.13
Values 0.75 0.89 0.62
[75]
SNU475 PER3
Mean 9.13
Standard deviation 2.6
Values 11 7.3
[76]
THLE PER3
Mean 1.19
Standard deviation 0.17
Values 1.1 1.3
[77]
liver PER3
Mean 11.6
Standard deviation 2.9
Values 10 13 8.3 15
[78]
ref_hepatocyte PER2
Mean 0.849
Standard deviation 0.32
Values 0.73 0.37 1.1 1.2 0.87
[79]
HepG2 PER2
Mean 6.11
Standard deviation 1.4
Values 5.1 7.1
[80]
HepG2.C3A PER2
Mean 6.05
Standard deviation 1.6
Values 7.2 4.9
[81]
HuH.7 PER2
Mean 15.1
Standard deviation 2
Values 17 14 14
[82]
SNU475 PER2
Mean 2.03
Standard deviation 0.44
Values 1.7 2.3
[83]
THLE PER2
Mean 1.77
Standard deviation 0.31
Values 1.5 2
[84]
liver PER2
Mean 6.67
Standard deviation 4.4
Values 2.4 12 3.6 9
[85]
ref_hepatocyte BHLHE41
Mean 0.125
Standard deviation 0.14
Values 0 0.12 0.043 0.37 0.089
[86]
HepG2 BHLHE41
Mean 0.655
Standard deviation 0.24
Values 0.49 0.82
[87]
HepG2.C3A BHLHE41
Mean 0.0146
Standard deviation 0.021
Values 0.029 0
[88]
HuH.7 BHLHE41
Mean 0.196
Standard deviation 0.13
Values 0.11 0.34 0.14
[89]
SNU475 BHLHE41
Mean 11.7
Standard deviation 0.45
Values 12 11
[90]
THLE BHLHE41
Mean 3.45
Standard deviation 0.92
Values 2.8 4.1
[91]
liver BHLHE41
Mean 0.147
Standard deviation 0.12
Values 0.1 0.31 0.026 0.16