KEGG_BIOSYNTHESIS_OF_UNSATURATED_FATTY_ACIDS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 SCD Acyl-CoA desaturase [1] 0.34[2] 0.93[3] 1.16[4] -1.30[5] -2.05[6] -0.03[7]
2 ACAA1 3-ketoacyl-CoA thiolase, peroxisomal [8] -1.49[9] -1.23[10] -3.65[11] -2.66[12] -2.19[13] -0.39[14]
3 HADHA Trifunctional enzyme subunit alpha, mitochondrial [15] 0.77[16] -0.15[17] -0.68[18] 0.43[19] 0.87[20] 0.11[21]
4 ELOVL5 Elongation of very long chain fatty acids protein 5 [22] -0.38[23] -1.48[24] -1.20[25] 1.40[26] 1.01[27] -1.51[28]
5 BAAT Bile acid-CoA:amino acid N-acyltransferase [29] -4.55[30] -5.17[31] -8.06[32] -6.58[33] -7.72[34] 1.22[35]
6 ACOT2 Acyl-coenzyme A thioesterase 2, mitochondrial [36] -1.66[37] -1.84[38] -5.03[39] -2.50[40] -2.04[41] -1.01[42]
7 TECR Very-long-chain enoyl-CoA reductase [43] 0.13[44] -1.50[45] -0.29[46] -0.10[47] 0.80[48] -0.94[49]
8 PECR Peroxisomal trans-2-enoyl-CoA reductase [50] -0.44[51] -0.13[52] -1.54[53] -1.68[54] -1.40[55] -0.89[56]
9 FADS2 Fatty acid desaturase 2 [57] -0.54[58] -0.32[59] 1.38[60] 2.01[61] -0.31[62] -0.93[63]
10 HSD17B12 Very-long-chain 3-oxoacyl-CoA reductase [64] -0.23[65] -0.22[66] -0.19[67] -0.47[68] 0.78[69] 0.48[70]
11 FADS1 Fatty acid desaturase 1 [71] 1.34[72] 1.20[73] 1.99[74] 2.19[75] 2.11[76] 0.63[77]
12 ACOT1 Acyl-coenzyme A thioesterase 1 [78] -2.17[79] -1.58[80] -6.23[81] -4.11[82] -3.81[83] -1.49[84]
13 ELOVL6 Elongation of very long chain fatty acids protein 6 [85] -1.80[86] 0.03[87] -0.43[88] 0.57[89] 1.46[90] -0.16[91]
14 ELOVL2 Elongation of very long chain fatty acids protein 2 [92] 0.96[93] 1.53[94] -0.31[95] -0.19[96] -2.06[97] -0.35[98]
15 ACOX1 Peroxisomal acyl-coenzyme A oxidase 1 [99] 1.89[100] 1.09[101] 0.05[102] 1.25[103] 1.07[104] 2.55[105]
16 ACOT7 Cytosolic acyl coenzyme A thioester hydrolase [106] 1.62[107] 0.99[108] -1.58[109] 2.04[110] 2.76[111] -2.25[112]
17 ACOX3 Peroxisomal acyl-coenzyme A oxidase 3 [113] 0.85[114] -0.78[115] -1.20[116] 0.83[117] 0.41[118] -0.22[119]
18 ACOT4 Acyl-coenzyme A thioesterase 4 [120] -8.15[121] -7.71[122] -3.93[123] 0.14[124] -2.30[125] 0.22[126]
19 YOD1 Ubiquitin thioesterase OTU1 [127] 1.95[128] 1.77[129] 2.30[130] 4.23[131] 3.94[132] 1.50[133]
20 SCD5 Stearoyl-CoA desaturase 5 [134] -2.65[135] -2.50[136] 0.11[137] 2.81[138] 4.52[139] -1.13[140]
21 HACD1 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 [141] [142] [143] [144] [145] [146] [147]
22 HACD2 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 [148] [149] [150] [151] [152] [153] [154]
[1]
ref_hepatocyte SCD
Mean 184
Standard deviation 1.7e+02
Values 4.1e+02 33 1.3e+02 35 3.1e+02
[2]
HepG2 SCD
Mean 263
Standard deviation 44
Values 2.3e+02 2.9e+02
[3]
HepG2.C3A SCD
Mean 832
Standard deviation 2.9e+02
Values 1e+03 6.3e+02
[4]
HuH.7 SCD
Mean 1.37e+03
Standard deviation 3.6e+02
Values 1.4e+03 1.7e+03 1e+03
[5]
SNU475 SCD
Mean 42.8
Standard deviation 2.4
Values 45 41
[6]
THLE SCD
Mean 25.4
Standard deviation 2.3
Values 24 27
[7]
liver SCD
Mean 369
Standard deviation 2.8e+02
Values 5.6e+02 1.1e+02 6.7e+02 1.4e+02
[8]
ref_hepatocyte ACAA1
Mean 118
Standard deviation 1e+02
Values 71 41 2.1e+02 25 2.5e+02
[9]
HepG2 ACAA1
Mean 47.6
Standard deviation 17
Values 35 60
[10]
HepG2.C3A ACAA1
Mean 119
Standard deviation 20
Values 1.3e+02 1.1e+02
[11]
HuH.7 ACAA1
Mean 31.3
Standard deviation 4
Values 27 32 35
[12]
SNU475 ACAA1
Mean 10.8
Standard deviation 2.1
Values 12 9.3
[13]
THLE ACAA1
Mean 14.9
Standard deviation 1.6
Values 14 16
[14]
liver ACAA1
Mean 185
Standard deviation 78
Values 1.2e+02 2.5e+02 2.5e+02 1.2e+02
[15]
ref_hepatocyte HADHA
Mean 82.4
Standard deviation 46
Values 1.4e+02 71 1.1e+02 20 69
[16]
HepG2 HADHA
Mean 159
Standard deviation 5.6
Values 1.6e+02 1.6e+02
[17]
HepG2.C3A HADHA
Mean 176
Standard deviation 53
Values 2.1e+02 1.4e+02
[18]
HuH.7 HADHA
Mean 170
Standard deviation 6.3
Values 1.8e+02 1.7e+02 1.6e+02
[19]
SNU475 HADHA
Mean 63.8
Standard deviation 14
Values 74 54
[20]
THLE HADHA
Mean 86
Standard deviation 10
Values 79 93
[21]
liver HADHA
Mean 182
Standard deviation 42
Values 1.5e+02 1.7e+02 2.4e+02 1.6e+02
[22]
ref_hepatocyte ELOVL5
Mean 56.8
Standard deviation 44
Values 1.2e+02 80 23 33 24
[23]
HepG2 ELOVL5
Mean 49.5
Standard deviation 3.3
Values 52 47
[24]
HepG2.C3A ELOVL5
Mean 48.2
Standard deviation 12
Values 56 40
[25]
HuH.7 ELOVL5
Mean 81.7
Standard deviation 21
Values 81 1e+02 61
[26]
SNU475 ELOVL5
Mean 86.1
Standard deviation 20
Values 1e+02 72
[27]
THLE ELOVL5
Mean 65.5
Standard deviation 8
Values 60 71
[28]
liver ELOVL5
Mean 40.8
Standard deviation 18
Values 37 29 68 30
[29]
ref_hepatocyte BAAT
Mean 50.1
Standard deviation 39
Values 1.6 59 89 17 84
[30]
HepG2 BAAT
Mean 2.42
Standard deviation 0.81
Values 1.9 3
[31]
HepG2.C3A BAAT
Mean 3.29
Standard deviation 0.29
Values 3.5 3.1
[32]
HuH.7 BAAT
Mean 0.621
Standard deviation 0.84
Values 0.098 1.6 0.18
[33]
SNU475 BAAT
Mean 0.302
Standard deviation 0.27
Values 0.49 0.11
[34]
THLE BAAT
Mean 0.136
Standard deviation 0.042
Values 0.17 0.11
[35]
liver BAAT
Mean 239
Standard deviation 1.3e+02
Values 1.7e+02 4.1e+02 2.7e+02 1.1e+02
[36]
ref_hepatocyte ACOT2
Mean 36.1
Standard deviation 30
Values 34 5.9 80 13 48
[37]
HepG2 ACOT2
Mean 13
Standard deviation 0.42
Values 13 13
[38]
HepG2.C3A ACOT2
Mean 23.9
Standard deviation 6.7
Values 29 19
[39]
HuH.7 ACOT2
Mean 3.66
Standard deviation 0.25
Values 3.4 3.7 3.9
[40]
SNU475 ACOT2
Mean 3.66
Standard deviation 0.54
Values 4 3.3
[41]
THLE ACOT2
Mean 5.01
Standard deviation 1.6
Values 3.9 6.1
[42]
liver ACOT2
Mean 36.7
Standard deviation 14
Values 22 55 35 35
[43]
ref_hepatocyte TECR
Mean 33.9
Standard deviation 31
Values 17 7.9 69 9.7 66
[44]
HepG2 TECR
Mean 41.9
Standard deviation 1.2
Values 43 41
[45]
HepG2.C3A TECR
Mean 28.5
Standard deviation 4.8
Values 32 25
[46]
HuH.7 TECR
Mean 92.1
Standard deviation 25
Values 1.1e+02 65 97
[47]
SNU475 TECR
Mean 18.2
Standard deviation 1.3
Values 17 19
[48]
THLE TECR
Mean 33.8
Standard deviation 0.066
Values 34 34
[49]
liver TECR
Mean 36.1
Standard deviation 38
Values 3.7 79 57 5.1
[50]
ref_hepatocyte PECR
Mean 28
Standard deviation 28
Values 34 4.9 30 1.2 70
[51]
HepG2 PECR
Mean 23.3
Standard deviation 4.2
Values 20 26
[52]
HepG2.C3A PECR
Mean 60.8
Standard deviation 2
Values 62 59
[53]
HuH.7 PECR
Mean 31.9
Standard deviation 3.6
Values 29 30 36
[54]
SNU475 PECR
Mean 5
Standard deviation 1.8
Values 6.3 3.7
[55]
THLE PECR
Mean 6.05
Standard deviation 0.43
Values 5.7 6.4
[56]
liver PECR
Mean 30.8
Standard deviation 12
Values 19 47 26 32
[57]
ref_hepatocyte FADS2
Mean 21
Standard deviation 10
Values 8.2 16 21 24 36
[58]
HepG2 FADS2
Mean 16.3
Standard deviation 4.9
Values 13 20
[59]
HepG2.C3A FADS2
Mean 39.8
Standard deviation 12
Values 49 31
[60]
HuH.7 FADS2
Mean 181
Standard deviation 24
Values 2.1e+02 1.7e+02 1.6e+02
[61]
SNU475 FADS2
Mean 48.4
Standard deviation 26
Values 67 30
[62]
THLE FADS2
Mean 9.67
Standard deviation 2.5
Values 7.9 11
[63]
liver FADS2
Mean 22.5
Standard deviation 17
Values 41 3.1 15 31
[64]
ref_hepatocyte HSD17B12
Mean 20.5
Standard deviation 14
Values 5.1 15 28 13 42
[65]
HepG2 HSD17B12
Mean 19.8
Standard deviation 1.3
Values 19 21
[66]
HepG2.C3A HSD17B12
Mean 41.8
Standard deviation 12
Values 50 34
[67]
HuH.7 HSD17B12
Mean 59.9
Standard deviation 5.1
Values 57 66 57
[68]
SNU475 HSD17B12
Mean 8.53
Standard deviation 0.57
Values 8.1 8.9
[69]
THLE HSD17B12
Mean 20.1
Standard deviation 2.8
Values 18 22
[70]
liver HSD17B12
Mean 58.4
Standard deviation 21
Values 62 56 83 32
[71]
ref_hepatocyte FADS1
Mean 17.1
Standard deviation 5.7
Values 21 20 11 22 10
[72]
HepG2 FADS1
Mean 48.8
Standard deviation 2.8
Values 51 47
[73]
HepG2.C3A FADS1
Mean 92.7
Standard deviation 11
Values 1e+02 85
[74]
HuH.7 FADS1
Mean 225
Standard deviation 35
Values 2.4e+02 2.5e+02 1.9e+02
[75]
SNU475 FADS1
Mean 44.8
Standard deviation 3.1
Values 47 43
[76]
THLE FADS1
Mean 42.2
Standard deviation 8
Values 37 48
[77]
liver FADS1
Mean 53.9
Standard deviation 20
Values 60 27 75 53
[78]
ref_hepatocyte ACOT1
Mean 15
Standard deviation 12
Values 22 1.9 22 2.8 26
[79]
HepG2 ACOT1
Mean 3.77
Standard deviation 0.82
Values 3.2 4.4
[80]
HepG2.C3A ACOT1
Mean 11.9
Standard deviation 3.2
Values 14 9.7
[81]
HuH.7 ACOT1
Mean 0.662
Standard deviation 0.15
Values 0.7 0.5 0.79
[82]
SNU475 ACOT1
Mean 0.499
Standard deviation 0.14
Values 0.6 0.4
[83]
THLE ACOT1
Mean 0.611
Standard deviation 0.14
Values 0.51 0.71
[84]
liver ACOT1
Mean 11
Standard deviation 4.4
Values 6.1 17 11 10
[85]
ref_hepatocyte ELOVL6
Mean 14.4
Standard deviation 6.8
Values 3 20 15 15 19
[86]
HepG2 ELOVL6
Mean 4.69
Standard deviation 0.45
Values 4.4 5
[87]
HepG2.C3A ELOVL6
Mean 34.9
Standard deviation 11
Values 42 27
[88]
HuH.7 ELOVL6
Mean 35.5
Standard deviation 5.9
Values 34 42 30
[89]
SNU475 ELOVL6
Mean 12.3
Standard deviation 1.9
Values 14 11
[90]
THLE ELOVL6
Mean 22.7
Standard deviation 1.3
Values 22 24
[91]
liver ELOVL6
Mean 26.3
Standard deviation 2.3
Values 27 24 29 25
[92]
ref_hepatocyte ELOVL2
Mean 11.4
Standard deviation 14
Values 36 6.9 3.6 0.76 10
[93]
HepG2 ELOVL2
Mean 25.1
Standard deviation 4.4
Values 22 28
[94]
HepG2.C3A ELOVL2
Mean 78.4
Standard deviation 3.4
Values 76 81
[95]
HuH.7 ELOVL2
Mean 30.6
Standard deviation 8.3
Values 28 40 24
[96]
SNU475 ELOVL2
Mean 5.74
Standard deviation 0.25
Values 5.9 5.6
[97]
THLE ELOVL2
Mean 1.56
Standard deviation 0.62
Values 2 1.1
[98]
liver ELOVL2
Mean 18.3
Standard deviation 11
Values 7.1 32 11 24
[99]
ref_hepatocyte ACOX1
Mean 11.2
Standard deviation 8.5
Values 15 4.5 11 2.3 23
[100]
HepG2 ACOX1
Mean 46.9
Standard deviation 9
Values 41 53
[101]
HepG2.C3A ACOX1
Mean 56.3
Standard deviation 2.2
Values 58 55
[102]
HuH.7 ACOX1
Mean 38.2
Standard deviation 5
Values 43 33 38
[103]
SNU475 ACOX1
Mean 15.2
Standard deviation 4.1
Values 18 12
[104]
THLE ACOX1
Mean 13.4
Standard deviation 1.8
Values 12 15
[105]
liver ACOX1
Mean 134
Standard deviation 77
Values 1.8e+02 63 75 2.2e+02
[106]
ref_hepatocyte ACOT7
Mean 9.64
Standard deviation 2.3
Values 10 9.9 7.2 13 7.8
[107]
HepG2 ACOT7
Mean 33.6
Standard deviation 2.1
Values 35 32
[108]
HepG2.C3A ACOT7
Mean 45.4
Standard deviation 0.95
Values 45 46
[109]
HuH.7 ACOT7
Mean 10.7
Standard deviation 3.3
Values 13 6.9 12
[110]
SNU475 ACOT7
Mean 22.7
Standard deviation 3.3
Values 25 20
[111]
THLE ACOT7
Mean 37.2
Standard deviation 5.9
Values 33 41
[112]
liver ACOT7
Mean 4.15
Standard deviation 2
Values 1.9 6.4 5.3 3
[113]
ref_hepatocyte ACOX3
Mean 5.95
Standard deviation 2.2
Values 6.9 8.5 6.2 2.5 5.7
[114]
HepG2 ACOX3
Mean 12.1
Standard deviation 0.48
Values 12 12
[115]
HepG2.C3A ACOX3
Mean 8.2
Standard deviation 1.7
Values 9.4 7
[116]
HuH.7 ACOX3
Mean 8.59
Standard deviation 1.1
Values 9.6 7.5 8.7
[117]
SNU475 ACOX3
Mean 6.09
Standard deviation 2.3
Values 7.7 4.5
[118]
THLE ACOX3
Mean 4.5
Standard deviation 0.81
Values 3.9 5.1
[119]
liver ACOX3
Mean 10.4
Standard deviation 1.4
Values 8.9 11 12 9.5
[120]
ref_hepatocyte ACOT4
Mean 3.95
Standard deviation 3.9
Values 0 1.7 8.2 1.8 8
[121]
HepG2 ACOT4
Mean 0.0158
Standard deviation 0.01
Values 0.023 0.0086
[122]
HepG2.C3A ACOT4
Mean 0.0447
Standard deviation 0.033
Values 0.068 0.021
[123]
HuH.7 ACOT4
Mean 0.861
Standard deviation 0.3
Values 0.86 0.56 1.2
[124]
SNU475 ACOT4
Mean 2.5
Standard deviation 0.18
Values 2.6 2.4
[125]
THLE ACOT4
Mean 0.457
Standard deviation 0.053
Values 0.42 0.49
[126]
liver ACOT4
Mean 9.44
Standard deviation 3.9
Values 6 14 12 6.2
[127]
ref_hepatocyte YOD1
Mean 1.25
Standard deviation 0.82
Values 1.2 2.6 0.55 1.4 0.59
[128]
HepG2 YOD1
Mean 5.46
Standard deviation 2.4
Values 3.8 7.1
[129]
HepG2.C3A YOD1
Mean 10.1
Standard deviation 0.78
Values 9.5 11
[130]
HuH.7 YOD1
Mean 20.3
Standard deviation 3.6
Values 23 22 16
[131]
SNU475 YOD1
Mean 13.5
Standard deviation 2.8
Values 15 12
[132]
THLE YOD1
Mean 10.9
Standard deviation 1.4
Values 12 9.9
[133]
liver YOD1
Mean 7.21
Standard deviation 2.7
Values 9.2 3.9 6 9.6
[134]
ref_hepatocyte SCD5
Mean 0.939
Standard deviation 0.9
Values 0.4 0.23 0.6 2.5 0.99
[135]
HepG2 SCD5
Mean 0.169
Standard deviation 0.052
Values 0.13 0.21
[136]
HepG2.C3A SCD5
Mean 0.395
Standard deviation 0.063
Values 0.35 0.44
[137]
HuH.7 SCD5
Mean 3.35
Standard deviation 0.81
Values 3.6 2.4 4
[138]
SNU475 SCD5
Mean 3.77
Standard deviation 0.22
Values 3.6 3.9
[139]
THLE SCD5
Mean 12.3
Standard deviation 0.84
Values 12 13
[140]
liver SCD5
Mean 0.879
Standard deviation 0.73
Values 1.3 0.19 0.33 1.7
[141]
ref_hepatocyte HACD1
Missing
[142]
HepG2 HACD1
Missing
[143]
HepG2.C3A HACD1
Missing
[144]
HuH.7 HACD1
Missing
[145]
SNU475 HACD1
Missing
[146]
THLE HACD1
Missing
[147]
liver HACD1
Missing
[148]
ref_hepatocyte HACD2
Missing
[149]
HepG2 HACD2
Missing
[150]
HepG2.C3A HACD2
Missing
[151]
HuH.7 HACD2
Missing
[152]
SNU475 HACD2
Missing
[153]
THLE HACD2
Missing
[154]
liver HACD2
Missing