KEGG_BETA_ALANINE_METABOLISM Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 ALDH2 Aldehyde dehydrogenase, mitochondrial [1] -1.22[2] -2.28[3] -1.71[4] -1.92[5] -1.85[6] -0.60[7]
2 ECHS1 Enoyl-CoA hydratase, mitochondrial [8] -0.96[9] -0.58[10] -0.57[11] -1.49[12] -1.23[13] -0.33[14]
3 HADHA Trifunctional enzyme subunit alpha, mitochondrial [15] 1.50[16] 1.63[17] 1.87[18] 1.28[19] 1.60[20] 0.48[21]
4 DPYS Dihydropyrimidinase [22] [23] [24] -14.13[25] -10.48[26] [27] 0.59[28]
5 ABAT 4-aminobutyrate aminotransferase, mitochondrial [29] 1.14[30] 0.69[31] -0.81[32] -6.84[33] -4.97[34] 1.02[35]
6 SMS Spermine synthase [36] 0.85[37] 0.44[38] 0.98[39] 1.79[40] 1.85[41] -2.76[42]
7 ALDH1B1 Aldehyde dehydrogenase X, mitochondrial [43] 1.04[44] 0.81[45] -0.84[46] 0.39[47] -0.08[48] -0.39[49]
8 ALDH9A1 4-trimethylaminobutyraldehyde dehydrogenase [50] -1.18[51] -0.59[52] 0.89[53] 0.97[54] 1.18[55] -0.11[56]
9 ALDH3A2 Fatty aldehyde dehydrogenase [57] 1.68[58] 1.41[59] 1.10[60] 1.81[61] 1.01[62] 0.26[63]
10 ACADM Medium-chain specific acyl-CoA dehydrogenase, mitochondrial [64] -0.29[65] 0.97[66] 0.48[67] 1.15[68] 0.28[69] 0.68[70]
11 UPB1 Beta-ureidopropionase [71] -6.76[72] -4.56[73] -2.64[74] -5.91[75] -11.03[76] -0.12[77]
12 EHHADH Peroxisomal bifunctional enzyme [78] -1.19[79] -0.60[80] 0.23[81] -0.71[82] -1.35[83] 1.49[84]
13 SRM Spermidine synthase [85] 1.15[86] 1.64[87] 0.42[88] 1.51[89] 1.87[90] -2.42[91]
14 HIBCH 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial [92] -0.53[93] 0.45[94] -0.27[95] 0.04[96] -0.10[97] 0.02[98]
15 ALDH7A1 Alpha-aminoadipic semialdehyde dehydrogenase [99] 2.34[100] 2.10[101] 2.13[102] 2.46[103] 2.88[104] 0.13[105]
16 CNDP1 Beta-Ala-His dipeptidase [106] -8.59[107] -7.69[108] -8.44[109] -8.91[110] -10.25[111] -0.64[112]
17 MLYCD Malonyl-CoA decarboxylase, mitochondrial [113] 0.20[114] 0.17[115] -0.02[116] -0.07[117] 0.25[118] 0.86[119]
18 DPYD Dihydropyrimidine dehydrogenase [NADP(+)] [120] -3.28[121] -2.50[122] 3.38[123] 3.27[124] 2.64[125] 3.23[126]
19 AOC3 Membrane primary amine oxidase [127] 3.57[128] 5.79[129] 2.72[130] 1.11[131] 1.10[132] 1.98[133]
20 AOC2 Retina-specific copper amine oxidase [134] 2.00[135] 2.61[136] 4.28[137] 3.37[138] 3.50[139] 0.32[140]
21 GAD1 Glutamate decarboxylase 1 [141] 2.50[142] 2.64[143] 6.24[144] 1.26[145] 2.48[146] -3.95[147]
22 GAD2 Glutamate decarboxylase 2 [148] [149] [150] [151] [152] [153] [154]
[1]
ref_hepatocyte ALDH2
Mean 413
Standard deviation 5.9e+02
Values 20 27 6.4e+02 22 1.4e+03
[2]
HepG2 ALDH2
Mean 122
Standard deviation 2.9
Values 1.2e+02 1.2e+02
[3]
HepG2.C3A ALDH2
Mean 58.8
Standard deviation 8.6
Values 65 53
[4]
HuH.7 ALDH2
Mean 71
Standard deviation 19
Values 81 49 83
[5]
SNU475 ALDH2
Mean 34.9
Standard deviation 8.2
Values 41 29
[6]
THLE ALDH2
Mean 39.5
Standard deviation 1.8
Values 38 41
[7]
liver ALDH2
Mean 429
Standard deviation 2.9e+02
Values 1.8e+02 7.1e+02 6.5e+02 1.8e+02
[8]
ref_hepatocyte ECHS1
Mean 234
Standard deviation 2.7e+02
Values 50 41 4.2e+02 36 6.2e+02
[9]
HepG2 ECHS1
Mean 82.5
Standard deviation 19
Values 69 96
[10]
HepG2.C3A ECHS1
Mean 108
Standard deviation 1.4
Values 1.1e+02 1.1e+02
[11]
HuH.7 ECHS1
Mean 88.7
Standard deviation 28
Values 93 59 1.1e+02
[12]
SNU475 ECHS1
Mean 26.6
Standard deviation 2.9
Values 29 25
[13]
THLE ECHS1
Mean 34.4
Standard deviation 3
Values 32 37
[14]
liver ECHS1
Mean 293
Standard deviation 2.8e+02
Values 64 6.2e+02 4.2e+02 63
[15]
ref_hepatocyte HADHA
Mean 82.4
Standard deviation 46
Values 1.4e+02 71 1.1e+02 20 69
[16]
HepG2 HADHA
Mean 159
Standard deviation 5.6
Values 1.6e+02 1.6e+02
[17]
HepG2.C3A HADHA
Mean 176
Standard deviation 53
Values 2.1e+02 1.4e+02
[18]
HuH.7 HADHA
Mean 170
Standard deviation 6.3
Values 1.8e+02 1.7e+02 1.6e+02
[19]
SNU475 HADHA
Mean 63.8
Standard deviation 14
Values 74 54
[20]
THLE HADHA
Mean 86
Standard deviation 10
Values 79 93
[21]
liver HADHA
Mean 182
Standard deviation 42
Values 1.5e+02 1.7e+02 2.4e+02 1.6e+02
[22]
ref_hepatocyte DPYS
Mean 68
Standard deviation 1e+02
Values 0 3.8 96 1.4 2.4e+02
[23]
HepG2 DPYS
Mean 0
Standard deviation 0
Values 0 0
[24]
HepG2.C3A DPYS
Mean 0
Standard deviation 0
Values 0 0
[25]
HuH.7 DPYS
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[26]
SNU475 DPYS
Mean 0.0152
Standard deviation 0.022
Values 0 0.03
[27]
THLE DPYS
Mean 0
Standard deviation 0
Values 0 0
[28]
liver DPYS
Mean 161
Standard deviation 36
Values 2.1e+02 1.6e+02 1.2e+02 1.6e+02
[29]
ref_hepatocyte ABAT
Mean 56.9
Standard deviation 75
Values 15 6 74 8.5 1.8e+02
[30]
HepG2 ABAT
Mean 86
Standard deviation 44
Values 55 1.2e+02
[31]
HepG2.C3A ABAT
Mean 63.3
Standard deviation 4.5
Values 60 66
[32]
HuH.7 ABAT
Mean 18.3
Standard deviation 4.1
Values 16 23 16
[33]
SNU475 ABAT
Mean 0.158
Standard deviation 0.027
Values 0.14 0.18
[34]
THLE ABAT
Mean 0.628
Standard deviation 0.091
Values 0.69 0.56
[35]
liver ABAT
Mean 182
Standard deviation 14
Values 2e+02 1.8e+02 1.7e+02 1.9e+02
[36]
ref_hepatocyte SMS
Mean 48.6
Standard deviation 41
Values 35 1.1e+02 12 65 18
[37]
HepG2 SMS
Mean 60
Standard deviation 5.2
Values 64 56
[38]
HepG2.C3A SMS
Mean 45.7
Standard deviation 8.7
Values 40 52
[39]
HuH.7 SMS
Mean 54.1
Standard deviation 17
Values 59 35 69
[40]
SNU475 SMS
Mean 53.5
Standard deviation 0.37
Values 53 54
[41]
THLE SMS
Mean 60.3
Standard deviation 9.2
Values 54 67
[42]
liver SMS
Mean 11.4
Standard deviation 7.2
Values 6 16 19 4.4
[43]
ref_hepatocyte ALDH1B1
Mean 46.8
Standard deviation 30
Values 84 73 22 19 36
[44]
HepG2 ALDH1B1
Mean 65.8
Standard deviation 15
Values 56 76
[45]
HepG2.C3A ALDH1B1
Mean 56.7
Standard deviation 1.3
Values 56 58
[46]
HuH.7 ALDH1B1
Mean 14.8
Standard deviation 4.6
Values 18 9.5 17
[47]
SNU475 ALDH1B1
Mean 19.6
Standard deviation 10
Values 27 12
[48]
THLE ALDH1B1
Mean 15.3
Standard deviation 3.4
Values 13 18
[49]
liver ALDH1B1
Mean 56.5
Standard deviation 35
Values 31 1.1e+02 57 32
[50]
ref_hepatocyte ALDH9A1
Mean 45
Standard deviation 33
Values 14 49 53 14 94
[51]
HepG2 ALDH9A1
Mean 13.7
Standard deviation 4.1
Values 11 17
[52]
HepG2.C3A ALDH9A1
Mean 20.8
Standard deviation 1.7
Values 20 22
[53]
HuH.7 ALDH9A1
Mean 47.2
Standard deviation 5.8
Values 43 54 45
[54]
SNU475 ALDH9A1
Mean 28.2
Standard deviation 2.2
Values 30 27
[55]
THLE ALDH9A1
Mean 35.2
Standard deviation 4.8
Values 32 39
[56]
liver ALDH9A1
Mean 65.7
Standard deviation 27
Values 50 78 97 38
[57]
ref_hepatocyte ALDH3A2
Mean 44.1
Standard deviation 25
Values 41 52 44 7.1 76
[58]
HepG2 ALDH3A2
Mean 97
Standard deviation 12
Values 89 1.1e+02
[59]
HepG2.C3A ALDH3A2
Mean 80.8
Standard deviation 15
Values 70 91
[60]
HuH.7 ALDH3A2
Mean 53.4
Standard deviation 2.9
Values 55 55 50
[61]
SNU475 ALDH3A2
Mean 49.4
Standard deviation 7.9
Values 55 44
[62]
THLE ALDH3A2
Mean 30.6
Standard deviation 2.4
Values 29 32
[63]
liver ALDH3A2
Mean 83.6
Standard deviation 21
Values 88 85 1.1e+02 55
[64]
ref_hepatocyte ACADM
Mean 39.4
Standard deviation 32
Values 44 26 34 3.6 90
[65]
HepG2 ACADM
Mean 22.1
Standard deviation 9.1
Values 16 29
[66]
HepG2.C3A ACADM
Mean 53.2
Standard deviation 10
Values 46 60
[67]
HuH.7 ACADM
Mean 30.9
Standard deviation 3.5
Values 32 27 33
[68]
SNU475 ACADM
Mean 27.8
Standard deviation 8
Values 33 22
[69]
THLE ACADM
Mean 16.5
Standard deviation 0.41
Values 17 16
[70]
liver ACADM
Mean 99.4
Standard deviation 56
Values 64 1.6e+02 1.3e+02 43
[71]
ref_hepatocyte UPB1
Mean 34.1
Standard deviation 46
Values 0.23 4 52 8 1.1e+02
[72]
HepG2 UPB1
Mean 0.216
Standard deviation 0.0023
Values 0.22 0.21
[73]
HepG2.C3A UPB1
Mean 1
Standard deviation 0.041
Values 0.97 1
[74]
HuH.7 UPB1
Mean 3.08
Standard deviation 0.98
Values 3.2 2 4
[75]
SNU475 UPB1
Mean 0.181
Standard deviation 0.11
Values 0.26 0.1
[76]
THLE UPB1
Mean 0.00562
Standard deviation 0.00042
Values 0.0059 0.0053
[77]
liver UPB1
Mean 49.6
Standard deviation 25
Values 30 75 67 26
[78]
ref_hepatocyte EHHADH
Mean 33.3
Standard deviation 41
Values 13 9 36 4.6 1e+02
[79]
HepG2 EHHADH
Mean 10
Standard deviation 5.1
Values 6.4 14
[80]
HepG2.C3A EHHADH
Mean 15.2
Standard deviation 3.7
Values 13 18
[81]
HuH.7 EHHADH
Mean 22
Standard deviation 3.4
Values 25 19 22
[82]
SNU475 EHHADH
Mean 6.51
Standard deviation 1.9
Values 7.9 5.1
[83]
THLE EHHADH
Mean 4.51
Standard deviation 0.22
Values 4.4 4.7
[84]
liver EHHADH
Mean 147
Standard deviation 40
Values 1e+02 1.9e+02 1.2e+02 1.8e+02
[85]
ref_hepatocyte SRM
Mean 28.1
Standard deviation 25
Values 6.5 15 33 70 16
[86]
HepG2 SRM
Mean 42.7
Standard deviation 0.29
Values 43 43
[87]
HepG2.C3A SRM
Mean 60.7
Standard deviation 5.5
Values 57 65
[88]
HuH.7 SRM
Mean 21.2
Standard deviation 10
Values 27 9.7 27
[89]
SNU475 SRM
Mean 25.5
Standard deviation 6.7
Values 21 30
[90]
THLE SRM
Mean 35.3
Standard deviation 5.7
Values 31 39
[91]
liver SRM
Mean 8.26
Standard deviation 6.7
Values 2.4 14 14 2.5
[92]
ref_hepatocyte HIBCH
Mean 17.4
Standard deviation 12
Values 9.9 13 32 4.1 29
[93]
HepG2 HIBCH
Mean 8.24
Standard deviation 3.1
Values 6 10
[94]
HepG2.C3A HIBCH
Mean 16.4
Standard deviation 5.1
Values 13 20
[95]
HuH.7 HIBCH
Mean 8.14
Standard deviation 3
Values 8.9 4.9 11
[96]
SNU475 HIBCH
Mean 5.71
Standard deviation 0.56
Values 6.1 5.3
[97]
THLE HIBCH
Mean 5.58
Standard deviation 0.28
Values 5.8 5.4
[98]
liver HIBCH
Mean 27.8
Standard deviation 18
Values 15 50 35 11
[99]
ref_hepatocyte ALDH7A1
Mean 17.3
Standard deviation 15
Values 24 6.2 16 1 39
[100]
HepG2 ALDH7A1
Mean 60.1
Standard deviation 16
Values 49 72
[101]
HepG2.C3A ALDH7A1
Mean 51.1
Standard deviation 14
Values 41 61
[102]
HuH.7 ALDH7A1
Mean 42.6
Standard deviation 10
Values 48 31 49
[103]
SNU475 ALDH7A1
Mean 30.3
Standard deviation 10
Values 38 23
[104]
THLE ALDH7A1
Mean 43.7
Standard deviation 3.2
Values 41 46
[105]
liver ALDH7A1
Mean 30
Standard deviation 18
Values 17 50 40 14
[106]
ref_hepatocyte CNDP1
Mean 10.5
Standard deviation 16
Values 0 0.48 14 1.6 36
[107]
HepG2 CNDP1
Mean 0.0186
Standard deviation 0.01
Values 0.011 0.026
[108]
HepG2.C3A CNDP1
Mean 0.035
Standard deviation 0.019
Values 0.049 0.021
[109]
HuH.7 CNDP1
Mean 0.017
Standard deviation 0.011
Values 0.016 0.0064 0.028
[110]
SNU475 CNDP1
Mean 0.00696
Standard deviation 0.0098
Values 0.014 0
[111]
THLE CNDP1
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[112]
liver CNDP1
Mean 10.6
Standard deviation 11
Values 10 2.8 26 3.5
[113]
ref_hepatocyte MLYCD
Mean 9.36
Standard deviation 8.7
Values 2.4 2.7 19 3.9 18
[114]
HepG2 MLYCD
Mean 7.35
Standard deviation 1.3
Values 6.4 8.3
[115]
HepG2.C3A MLYCD
Mean 7.3
Standard deviation 0.37
Values 7.6 7
[116]
HuH.7 MLYCD
Mean 5.21
Standard deviation 0.55
Values 5.2 4.7 5.8
[117]
SNU475 MLYCD
Mean 2.84
Standard deviation 1
Values 3.6 2.1
[118]
THLE MLYCD
Mean 3.83
Standard deviation 0.37
Values 3.6 4.1
[119]
liver MLYCD
Mean 26.8
Standard deviation 5.4
Values 23 22 33 30
[120]
ref_hepatocyte DPYD
Mean 5.41
Standard deviation 7.8
Values 0.66 1.2 5.5 0.79 19
[121]
HepG2 DPYD
Mean 0.381
Standard deviation 0.23
Values 0.22 0.54
[122]
HepG2.C3A DPYD
Mean 0.663
Standard deviation 0.13
Values 0.76 0.57
[123]
HuH.7 DPYD
Mean 31.7
Standard deviation 5.8
Values 29 38 28
[124]
SNU475 DPYD
Mean 16.6
Standard deviation 0.43
Values 17 16
[125]
THLE DPYD
Mean 11.6
Standard deviation 1
Values 11 12
[126]
liver DPYD
Mean 80.3
Standard deviation 30
Values 93 69 45 1.1e+02
[127]
ref_hepatocyte AOC3
Mean 0.938
Standard deviation 0.67
Values 1.2 0 1.4 0.5 1.6
[128]
HepG2 AOC3
Mean 7.65
Standard deviation 3
Values 9.8 5.5
[129]
HepG2.C3A AOC3
Mean 35.8
Standard deviation 5.7
Values 40 32
[130]
HuH.7 AOC3
Mean 3.49
Standard deviation 0.42
Values 3.1 3.9 3.5
[131]
SNU475 AOC3
Mean 0.646
Standard deviation 0.46
Values 0.32 0.97
[132]
THLE AOC3
Mean 0.692
Standard deviation 0.44
Values 1 0.38
[133]
liver AOC3
Mean 5.85
Standard deviation 3.6
Values 4.7 2.7 11 5.1
[134]
ref_hepatocyte AOC2
Mean 0.43
Standard deviation 0.52
Values 0 0.36 0.53 1.3 0
[135]
HepG2 AOC2
Mean 1.18
Standard deviation 0.25
Values 1.4 1
[136]
HepG2.C3A AOC2
Mean 1.82
Standard deviation 0.54
Values 2.2 1.4
[137]
HuH.7 AOC2
Mean 4.72
Standard deviation 0.32
Values 4.4 4.7 5
[138]
SNU475 AOC2
Mean 1.42
Standard deviation 0.78
Values 0.87 2
[139]
THLE AOC2
Mean 1.67
Standard deviation 0.78
Values 2.2 1.1
[140]
liver AOC2
Mean 0.848
Standard deviation 0.61
Values 0.98 0.19 0.59 1.6
[141]
ref_hepatocyte GAD1
Mean 0.132
Standard deviation 0.29
Values 0 0.66 0 0 0
[142]
HepG2 GAD1
Mean 0.511
Standard deviation 0.23
Values 0.67 0.35
[143]
HepG2.C3A GAD1
Mean 0.567
Standard deviation 0.17
Values 0.45 0.69
[144]
HuH.7 GAD1
Mean 5.59
Standard deviation 0.85
Values 4.9 6.5 5.4
[145]
SNU475 GAD1
Mean 0.101
Standard deviation 0.044
Values 0.07 0.13
[146]
THLE GAD1
Mean 0.253
Standard deviation 0.1
Values 0.33 0.18
[147]
liver GAD1
Mean 0.0135
Standard deviation 0.019
Values 0.014 0 0 0.04
[148]
ref_hepatocyte GAD2
Mean 0.0065
Standard deviation 0.015
Values 0 0 0 0 0.033
[149]
HepG2 GAD2
Missing
[150]
HepG2.C3A GAD2
Missing
[151]
HuH.7 GAD2
Missing
[152]
SNU475 GAD2
Missing
[153]
THLE GAD2
Missing
[154]
liver GAD2
Missing