KEGG_ALANINE_ASPARTATE_AND_GLUTAMATE_METABOLISM |
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Order |
Gene |
Description |
ref_hepatocyte |
HepG2 |
HepG2.C3A |
HuH.7 |
SNU475 |
THLE |
liver |
1 |
AGXT |
Serine--pyruvate aminotransferase |
[1] |
-6.83[2] |
-3.47[3] |
-9.57[4] |
-12.70[5] |
-14.71[6] |
-0.55[7] |
2 |
ASS1 |
Argininosuccinate synthase |
[8] |
-1.68[9] |
-2.09[10] |
-1.12[11] |
-2.05[12] |
-2.09[13] |
-1.73[14] |
3 |
GLUD1 |
Glutamate dehydrogenase 1, mitochondrial |
[15] |
0.70[16] |
1.40[17] |
0.84[18] |
-0.57[19] |
0.11[20] |
0.34[21] |
4 |
CPS1 |
Carbamoyl-phosphate synthase [ammonia], mitochondrial |
[22] |
-2.39[23] |
-2.98[24] |
-2.53[25] |
-8.94[26] |
-2.45[27] |
1.85[28] |
5 |
ALDH4A1 |
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial |
[29] |
0.57[30] |
1.56[31] |
-2.07[32] |
-1.05[33] |
-2.23[34] |
0.24[35] |
6 |
ASL |
Argininosuccinate lyase |
[36] |
-0.63[37] |
-1.28[38] |
0.23[39] |
-0.07[40] |
-1.71[41] |
-0.56[42] |
7 |
GOT1 |
Aspartate aminotransferase, cytoplasmic |
[43] |
0.26[44] |
1.17[45] |
0.31[46] |
-0.99[47] |
-0.25[48] |
-0.31[49] |
8 |
GLUL |
Glutamine synthetase |
[50] |
0.61[51] |
1.10[52] |
2.09[53] |
-0.03[54] |
1.00[55] |
0.83[56] |
9 |
GOT2 |
Aspartate aminotransferase, mitochondrial |
[57] |
1.14[58] |
-0.03[59] |
0.84[60] |
1.10[61] |
1.97[62] |
0.02[63] |
10 |
ABAT |
4-aminobutyrate aminotransferase, mitochondrial |
[64] |
1.01[65] |
0.00[66] |
-1.04[67] |
-6.52[68] |
-4.88[69] |
0.47[70] |
11 |
NIT2 |
Omega-amidase NIT2 |
[71] |
-1.16[72] |
-1.73[73] |
-1.08[74] |
-0.12[75] |
0.10[76] |
-1.22[77] |
12 |
GPT |
Alanine aminotransferase 1 |
[78] |
-4.46[79] |
-3.88[80] |
-4.43[81] |
-4.09[82] |
-7.04[83] |
-1.27[84] |
13 |
ADSL |
Adenylosuccinate lyase |
[85] |
1.71[86] |
1.18[87] |
2.26[88] |
1.86[89] |
1.74[90] |
-1.96[91] |
14 |
AGXT2 |
Alanine--glyoxylate aminotransferase 2, mitochondrial |
[92] |
-8.11[93] |
-9.76[94] |
0.20[95] |
-7.78[96] |
-9.41[97] |
-0.49[98] |
15 |
GLS2 |
Glutaminase liver isoform, mitochondrial |
[99] |
-0.93[100] |
-1.08[101] |
-4.72[102] |
-4.25[103] |
-3.92[104] |
-0.22[105] |
16 |
GPT2 |
Alanine aminotransferase 2 |
[106] |
3.75[107] |
2.66[108] |
1.45[109] |
0.77[110] |
2.04[111] |
0.77[112] |
17 |
ALDH5A1 |
Succinate-semialdehyde dehydrogenase, mitochondrial |
[113] |
1.32[114] |
0.74[115] |
-0.42[116] |
1.08[117] |
-1.27[118] |
-0.15[119] |
18 |
GLS |
Glutaminase kidney isoform, mitochondrial |
[120] |
2.84[121] |
2.94[122] |
2.55[123] |
5.82[124] |
4.02[125] |
-1.25[126] |
19 |
GFPT1 |
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 |
[127] |
2.97[128] |
3.26[129] |
3.74[130] |
4.11[131] |
3.75[132] |
1.91[133] |
20 |
ASNS |
Asparagine synthetase [glutamine-hydrolyzing] |
[134] |
4.39[135] |
3.66[136] |
4.02[137] |
2.79[138] |
4.42[139] |
-2.10[140] |
21 |
ACY3 |
N-acyl-aromatic-L-amino acid
amidohydrolase (carboxylate-forming) |
-0.90[141] |
-1.56[142] |
0.52[143] |
0.86[144] |
-6.73[145] |
-1.38[146] |
22 |
DDO |
D-aspartate oxidase |
[147] |
-0.17[148] |
-2.65[149] |
-6.25[150] |
-0.59[151] |
-0.96[152] |
-1.40[153] |
23 |
PPAT |
Amidophosphoribosyltransferase |
[154] |
2.79[155] |
2.60[156] |
3.40[157] |
3.58[158] |
3.95[159] |
-0.42[160] |
24 |
CAD |
CAD protein |
[161] |
4.88[162] |
4.05[163] |
5.18[164] |
5.99[165] |
5.91[166] |
1.53[167] |
25 |
GLUD2 |
Glutamate dehydrogenase 2, mitochondrial |
[168] |
-6.48[169] |
-5.60[170] |
1.92[171] |
-4.96[172] |
-2.69[173] |
-0.60[174] |
26 |
ASPA |
Aspartoacylase |
[175] |
[176] |
-5.68[177] |
-2.13[178] |
-0.45[179] |
-0.88[180] |
-0.18[181] |
27 |
IL4I1 |
L-amino-acid oxidase |
[182] |
-3.20[183] |
-4.84[184] |
-1.02[185] |
2.75[186] |
0.48[187] |
-2.02[188] |
28 |
GFPT2 |
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 |
[189] |
2.38[190] |
-0.38[191] |
0.78[192] |
8.07[193] |
10.10[194] |
0.53[195] |
29 |
GAD1 |
Glutamate decarboxylase 1 |
[196] |
2.37[197] |
1.95[198] |
6.00[199] |
1.58[200] |
2.56[201] |
-4.49[202] |
30 |
GAD2 |
Glutamate decarboxylase 2 |
[203] |
[204] |
[205] |
[206] |
[207] |
[208] |
[209] |
31 |
ADSS2 |
|
[210] |
[211] |
[212] |
[213] |
[214] |
[215] |
[216] |
32 |
ADSS1 |
|
[217] |
[218] |
[219] |
[220] |
[221] |
[222] |
[223] |
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