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Yun Liang, PhD

Research Investigator, Department of Dermatology

Selected Publications

  1. Fu Y, Wu X, Han Q, Liang Y, He Y, Luo Y. Sulfate stabilizes the folding intermediate more than the native structure of endostatin. Arch Biochem Biophys. 471(2):232-9. (2008)
  2. Fu Y, Chen Y, Luo X, Liang Y, Shi H, Gao L, Zhan S, Zhou D, Luo Y. The heparin binding motif of endostatin mediates its interaction with receptor nucleolin. Biochemistry. 48(49):11655-63. (2009)
  3. Wang X, Song X, Zhuo W, Fu Y, Shi H, Liang Y, Tong M, Chang G, Luo Y. The regulatory mechanism of Hsp90alpha secretion and its function in tumor malignancy. Proc Natl Acad Sci U S A. 106(50):21288-93. (2009)
  4. Song X, Wang X, Zhuo W, Shi H, Feng D, Sun Y, Liang Y, Fu Y, Zhou D, Luo Y. The regulatory mechanism of extracellular Hsp90a on matrix metalloproteinase-2 processing and tumor angiogenesis. J Biol Chem. 285(51):40039-49. (2010)
  5. Capelson M, Liang Y, Schulte R, Mair W, Wagner U, Hetzer MW. Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes. Cell. 140(3):372-83. (2010)
  6. Liang Y, Hetzer MW. Functional interactions between nucleoporins and chromatin. Curr Opin Cell Biol. 23(1):65-70. (2011)
  7. Liang Y, Franks TM, Marchetto MC, Gage FH, Hetzer MW. Dynamic association of NUP98 with the human genome PLoS Genet. 9(2):e1003308. (2013)
  8. Buchwalter AL, Liang Y, Hetzer MW. Nup50 is required for cell differentiation and exhibits transcription-dependent dynamics. Mol Biol Cell. 25(16):2472-84. (2014)
  9. Swindell WR, Sarkar MK, Liang Y, Xing X, Gudjonsson JE. Cross-disease transcriptomics: Unique IL-17A signaling in psoriasis lesions and an autoimmune PBMC signature. J Invest Dermatol. 136(9):1820-30. (2016).
  10. Xing X, Liang Y, Sarkar MK, Wolterink L, Swindell WR, Voorhees JJ, Harms PW, Kahlenberg JM, Johnston A, Gudjonsson JE. IL-17 Responses Are the Dominant Inflammatory Signal Linking Inverse, Erythrodermic, and Chronic Plaque Psoriasis. J Invest Dermatol. 136(12):2498-2501. (2016)
  11. Liang Y, Xing X, Beamer MA, Swindell WR, Sarkar MK, Roberts LW, Voorhees JJ, Kahlenberg JM, Harms PW, Johnston A, Gudjonsson JE. STEAPs comprise a novel inflammatory nexus in pustular skin disorders. J Allergy Clin Immunol. pii: S0091-6749(16)31351-3. doi: 10.1016/j.jaci.2016.10.021. [Epub ahead of print] (2016)
  12. Liang Y, Gudjonsson JE. WASP, Tregs, and food allergies - rare disease provides insight into a common problem. J Clin Invest. 126(10):3728-3730. (2016)
  13. Liang Y, Tsoi LC, Xing X, Beamer MA, Swindell WR, Sarkar MK, Berthier CC, Stuart PE, Harms PW, Nair RP, Elder JT, Voorhees JJ, Kahlenberg JM, Gudjonsson JE. VGLL3-regulated gene network as a promoter of gender biased autoimmune diseases. Nat Immunol. Accepted. (2016)


 

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