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The Vector Core produces biological products (gene transfer vectors) that facilitate the transfer of specific genes into either normal or aberrant cells. The Vector Core also provides intellectual and technical advice to researchers regarding the optimal use of these systems. Gene transfer vectors require special handling precautions, and manufacturing systems that lend themselves to a core structure that optimizes efficiencies of scale and cost to the research community.
The specific objectives of the Vector Core are to:
- Provide a Core laboratory for the construction, purification and
characterization of recombinant vectors containing genes relevant to the study
of disease models for use as in vitro and in vivo gene transfer reagents.
These systems include both non-viral (expression plasmid) and viral
(recombinant lentivirus, recombinant retrovirus, and recombinant adenovirus)
- Collaborate closely with researchers to ensure the Vector Core provides
the platforms our customers require, and to institute the use
of new technologies;
- Maintain qualified staff and provide high quality, cost effective products to our researchers.
Thomas Lanigan, Ph.D.
Supervisor, Vector Core