MECHANISM-SPECIFIC APPROACH TO SLEEP DISORDERS

  • Identify Symptoms:
    - primary insomnia vs. secondary insomnia
    - excessive daytime sleepiness
    - obstructive sleep apnea

  • Separate therapy responders and non-responders

  • Identify biomarkers for heritable signs

  • Develop pre-clinical phenotypes:
    - behavioral
    - neurochemical
    - electrographic
    - metabolic

 

Copyright 2014 UM Center for Sleep Science