The Transgenic Facility routinely produces
transgenic rats for biomedical research. We have developed considerable
expertise in this area (Filipiak
and Saunders, 2006). The general outline
of producing transgenic rats and transgenic mice is the same.
The efficiency of transgenic rat production is
equivalent to the production of transgenic mice in inbred mouse strains
such as C57BL/6J.
We have generate transgenic rats in the following
Fischer 344 Rats - F344/NHsd
Long Evans Rats - Crl:LE
Sprague Dawley Rats - Crl:CD (SD)
Wistar Rats - Crl:Wi
We have successfully generated
plasmid transgene transgenic rats
bacterail artificial chromosome transgenic rats
knockout rats by the pronuclear microinjection of zinc finger nuclease mRNA.
If you are interested in obtaining transgenic rats from the Transgenic Facility, please contact firstname.lastname@example.org for more information.