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    • 2008
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    Akyol A, Hinoi T, Feng Y, Bommer GT, Glaser TM, Fearon ER. 2008. Generating somatic mosaicism with a Cre recombinase-microsatellite sequence transgene. Nat Methods. 5:231-233.

    Albertelli MA, O'Mahony OA, Brogley M, Tosoian J, Steinkamp M, Daignault S, Wojno K, Robins DM. 2008. Glutamine tract length of human androgen receptors affects hormone-dependent and -independent prostate cancer in mice. Hum Mol Genet.17:98-110.

    Feathers KL, Lyubarsky AL, Khan NW, Teofilo K, Swaroop A, Williams DS, Pugh EN Jr, Thompson DA. 2008. Nrl-Knockout Mice Deficient in Rpe65 Fail to Synthesize 11-cis Retinal and Cone Outer Segments. Invest Ophthalmol Vis Sci. 49: 1126-35.

    Huang X, Charbeneau RA, Fu Y, Kaur K, Gerin I, MacDougald OA, Neubig RR. 2008. Resistance to diet-induced obesity and improved insulin sensitivity in mice with a regulator of G protein signaling-insensitive G184S Gnai2 allele. Diabetes. 57:77-85.

    Johnsen JM, Levy GG, Westrick RJ, Tucker PK, Ginsburg D. 2008. The endothelial-specific regulatory mutation, Mvwf1, is a common mouse founder allele. Mamm Genome.  19:32-40.

    Kim J, Lauderdale JD. 2008. Overexpression of pairedless Pax6 in the retina disrupts corneal development and affects lens cell survival. Dev Biol. 313:434-454.

    Oh EC, Cheng H, Hao H, Jia L, Khan NW, Swaroop A. Rod differentiation factor NRL activates the expression of nuclear receptor NR2E3 to suppress the development of cone photoreceptors. Brain Res. 2008 Jan 18 [Epub ahead of print]

    Robins DM, Albertelli MA, O’Mahony OA. Androgen receptor variants and prostate cancer in humanized AR mice. J Steroid Biochem Mol Biol. 2008 Feb; 108(3-5): 230-6.

    Tessari A, Pietrobon M, Notte A, Cifelli G, Gage PJ, Schneider MD, Lembo G, Campione M. Myocardial Pitx2 Differentially Regulates the Left Atrial Identity and Ventricular Asymmetric Remodeling Programs. Circ Res 2008 (Epub ahead of print).
    2007

    Top Home
    Adams ME, Hurd EA, Beyer LA, Swiderski DL, Raphael Y, Martin DM. 2007. Defects in vestibular sensory epithelia and innervation in mice with loss of Chd7 function: implications for human CHARGE syndrome. J Comp Neurol.  504: 519-32.

    Bauler TJ, Hughes ED, Arimura Y,Mustelin T,Saunders TL, King PD.2007. Normal TCR signal transduction in mice that lack catalytically active PTPN3 protein tyrosine phosphatase.  J Immunol. 178:3680-3687.

    Bennett CN, Ouyang H, Ma YL, Zeng Q, Gerin I, Sousa KM, Lane TF, Krishnan V, Hankenson KD, MacDougald OA. 2007. Wnt10b increases postnatal bone formation by enhancing osteoblast differentiation. J Bone Miner Res.22:1924-32.

    Bradley SV. Hyun TS. Oravecz-Wilson KI. Li L. Waldorff EI. Ermilov AN. Goldstein SA. Zhang CX. Drubin DG. Varela K. Parlow A. Dlugosz AA. Ross TS. 2007. Degenerative phenotypes caused by the combined deficiency of murine HIP1 and HIP1r are rescued by human HIP1.  Human Molecular Genetics. 16:1279-92,

    Chen C, Dickendesher DL, Oyama F, Miyazaki H, Nukina N, Isom LL. 2007. Floxed allele for conditional inactivation of the voltage-gated sodium channel 1 subunit Scn1b. Genesis. 45:547-553.

    Costa-Mattioli M, Gobert D, Stern E, Gamache K, Colina R, Cuello C, Sossin W, Kaufman R, Pelletier J, Rosenblum K, Krnjević K, Lacaille JC, Nader K, Sonenberg N. 2007. eIF2alpha phosphorylation bidirectionally regulates the switch from short- to long-term synaptic plasticity and memory. Cell.129:195-206.

    Davis SW, Camper SA.  Noggin regulates Bmp4 activity during pituitary induction. Dev Biol. 2007 Feb 7; [Epub ahead of print]

    Dentice M, Luongo C, Huang S, Ambrosio R, Elefante A, Mirebeau-Prunier D, Zavacki AM, Fenzi G, Grachtchouk M, Hutchin M, Dlugosz AA, Bianco AC, Missero C, Larsen PR, Salvatore D.  2007. Sonic hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes. Proc Natl Acad Sci U S A. 104:14466-14471.

    Domino SE, Karnak DM, Hurd EA. 2007. Cell surface fucosylation does not affect development of colon tumors in mice with germline Smad3 mutation. Tumour Biol. 28:77-83.

    Drews VL, Shi K, de Haan G, Meisler MH. 2007. Identification of evolutionarily conserved, functional noncoding elements in the promoter region of the sodium channel gene SCN8A. Mamm Genome. 18:723-731.

    Elmore CL, Matthews RG. 2007. The many flavors of hyperhomocyst(e)inemia: insights from transgenic and inhibitor-based mouse models of disrupted one-carbon metabolism. Antioxid Redox Signal.9:1911-1921.

    Elmore CL, Wu X, Leclerc D, Watson ED, Bottiglieri T, Krupenko NI, Krupenko SA, Cross JC, Rozen R, Gravel RA, Matthews RG. 2007. Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase. Mol Genet Metab. 91:85-97.

    Fu Y, Huang X, Piao L, Lopatin AN, Neubig RR. 2007. Endogenous RGS proteins modulate SA and AV nodal functions in isolated heart: implications for sick sinus syndrome and AV block. Am J Physiol Heart Circ Physiol. 292:H2532-9.

    Ge C, Xiao G, Jiang D, Franceschi RT. 2007. Critical role of the extracellular signal-regulated kinase-MAPK pathway in osteoblast differentiation and skeletal development. J Cell Biol. 176:709-718.

    Haremaki T, Fraser ST, Kuo YM, Baron MH, Weinstein DC. 2007. Vertebrate Ctr1 coordinates morphogenesis and progenitor cell fate and regulates embryonic stem cell differentiation. Proc Natl Acad Sci U S A.104:12029-34.

    Harvey SJ, Jarad G, Cunningham J, Rops AL, van der Vlag J, Berden JH, Moeller MJ, Holzman LB, Burgess RW, Miner JH. 2007. Disruption of Glomerular Basement Membrane Charge through Podocyte-Specific Mutation of Agrin Does Not Alter Glomerular Permselectivity. Am J Pathol. 171:139–152.

    Hinoi T, Akyol A, Theisen BK, Ferguson DO, Greenson JK, Williams BO, Cho KR, Fearon ER. 2007    . Mouse model of colonic adenoma-carcinoma progression based on somatic apc inactivation. Cancer Res. 67: 9721-30.

    Hu Y, Shen H, Keep RF, Smith DE. 2007. Peptide transporter 2 (PEPT2) expression in brain protects against 5-aminolevulinic acid neurotoxicity.
    J Neurochem. 103:2058-2065.

    Huang X, Charbeneau RA, Fu Y, Kaur K, Gerin I, Macdougald OA, Neubig RR. Resistance to diet-induced obesity and improved insulin sensitivity in mice with an RGS insensitive G184S Gnai2 allele. Diabetes. 2007 Oct 10 (Epub of print).

    Hughes ED, Qu YY, Genik SJ, Lyons RH, Pacheco CD, Lieberman AP, Samuelson LC, Nasonkin IO, Camper SA, Van Keuren ML, Saunders TL. 2007. Genetic variation in C57BL/6 ES cell lines and genetic instability in the Bruce4 C57BL/6 ES cell line. Mamm Genome. 18:549-558.

    Hurd EA, Capers PL, Blauwkamp MN, Adams ME,  Raphael T, Poucher HK, Martin DM. 2007. Loss of Chd7 function in gene-trapped reporter mice is embryonic lethal and associated with severe defects in multiple developing tissues. Mamm. Genome. 18:94-104.

    Jain RN, Samuelson LC. 2007. Transcriptional Profiling of Gastrin-Regulated Genes in Mouse Stomach. Physiol Genomics. 29;1-12.

    Kim I, Saunders TL, Morrison SJ. 2007.  Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cells. Cell.130:470-483.

    Kim D. Wang M. Cai Q. Brooks H. Dressler GR. 2007. Pax transactivation-domain interacting protein is required for urine concentration and osmotolerance in collecting duct epithelia. Journal of the American Society of Nephrology. 18:1458-1465.

    Lapinski PE, Bauler TJ, Brown EJ, Hughes ED, Saunders TL, King PD. 2007. Generation of mice with a conditional allele of the p120 Ras GTPase-activating protein.
    Genesis. 45:762-767.

    Lehoczky JA, Innis JW. 2007. A mouse transgene drives embryonic dorsal posterior commissure expression. Transgenic Res. 16:823-8.

    López-Díaz L, Jain RN, Keeley TM, VanDussen KL, Brunkan CS, Gumucio DL, Samuelson LC. 2007. Intestinal Neurogenin 3 directs differentiation of a bipotential secretory progenitor to endocrine cell rather than goblet cell fate. Dev Biol. 309:298-305.

    Matthews RG, Elmore CL. 2007. Defects in homocysteine metabolism: diversity among hyperhomocyst(e)inemias. Clin Chem Lab Med. 45:1700-1703.

    Nenci A, Becker C, Wullaert A, Gareus R, van Loo G, Danese S, Huth M, Nikolaev A, Neufert C, Madison B, Gumucio D, Neurath MF, Pasparakis M. 2007. Epithelial NEMO links innate immunity to chronic intestinal inflammation. Nature. 446:557-61.

    Newell-Litwa K, Seong E, Burmeister M, Faundez V. 2007. Neuronal and non-neuronal functions of the AP-3 sorting machinery. J Cell Sci. 120(Pt 4):531-541.

    Noujaim SF, Pandit SV, Berenfeld O, Vikstrom K, Cerrone M, Mironov S, Zugermayr M, Lopatin AN, Jalife J. 2007. Up-regulation of the inward rectifier K+ current (IK1) in the mouse heart accelerates and stabilizes rotors. J Physiol. 578(Pt 1):315-26.

    Oh EC, Khan N, Novelli E, Khanna H, Strettoi E, Swaroop A. 2007. Transformation of cone precursors to functional rod photoreceptors by bZIP transcription factor NRL. PNAS (USA) 104:1679–1684.

    Piao L, Li J, McLerie M, Lopatin AN. 2007.  Transgenic upregulation of IK1 in the mouse heart is proarrhythmic. Basic Res Cardiol. 102:416-28.

    Piao L, Li J, McLerie M, Lopatin AN. 2007.Cardiac IK1 underlies early action potential shortening during hypoxia in the mouse heart. J Mol Cell Cardiol. 43:27-38.

    Qiao XT. Ziel JW. McKimpson W. Madison BB. Todisco A. Merchant JL. Samuelson LC. Gumucio DL. 2007. Prospective identification of a multilineage progenitor in murine stomach epithelium. Gastroenterology. 133:1989-1998,

    Raven MA, Oh EC, Swaroop A, Reese BE. 2007. Afferent control of horizontal cell morphology revealed by genetic respecification of rods and cones. J Neurosci. 27:3540-3547.

    Raetzman LT, Cai JX, Camper SA.  2007. Hes1 is required for pituitary growth and melanotrope specification. Dev Biol. 304:455-466.

    Ren D, Zhou Y, Morris D, Li M, Li Z, Rui L. 2007. Neuronal SH2B1 is essential for controlling energy and glucose homeostasis. J Clin Invest. 117:397-406.

    Robins DM, Albertelli MA, O'mahony OA. 2007. Androgen receptor variants and prostate cancer in humanized AR mice.
    J Steroid Biochem Mol Biol. 2007 Sep 7; [Epub ahead of print]

    Rozeboom AM, Akil H, Seasholtz AF. 2007.  Mineralocorticoid receptor overexpression in forebrain decreases anxiety-like behavior and alters the stress response in mice. Proc Natl Acad Sci U S A.104:4688-4693.

    Shen H, Ocheltree SM, Hu Y, Kee, RF, Smith DE. 2007. Impact of genetic knockout of PEPT2 on cefadroxil pharmacokinetics, renal tubular reabsorption and brain penetration in mice. Drug Metabolism and Disposition.  35: 1209-1216.

    Soliman GA, Ishida-Takahashi R, Gong Y, Jones JC, Leshan RL, Saunders TL, Fingar DC, Myers MG Jr. 2007. A simple qPCR-based method to detect correct insertion of homologous targeting vectors in murine ES cells. Transgenic Res. 16:665-70.

    Suleiman H, Heudobler D, Raschta AS, Zhao Y, Zhao Q, Hertting I, Vitzthum H, Moeller MJ, Holzman LB, Rachel R, Johnson R, Westphal H, Rascle A, Witzgall R. 2007. The podocyte-specific inactivation of Lmx1b, Ldb1 and E2a yields new insight into a transcriptional network in podocytes. Dev Biol. 304:701-12.

    Wei Q, Hebda-Bauer EK, Pletsch A, Luo J, Hoversten MT, Osetek AJ, Evans SJ, Watson SJ, Seasholtz AF, Akil H. 2007. Overexpressing the glucocorticoid receptor in forebrain causes an aging-like neuroendocrine phenotype and mild cognitive dysfunction. J Neurosci. 37:8836-8844.

    Wiggins RC. 2007. The spectrum of podocytopathies: A unifying view of glomerular diseases. Kidney Int. 71:1205-14.

    Wright WS, Longo KA, Dolinsky VW, Gerin I, Kang S, Bennett CN, Chiang SH, Prestwich TC, Gress C, Burant CF, Susulic VS, MacDougald OA. 2007. Wnt10b inhibits obesity in ob/ob and agouti mice. Diabetes. 56:295-303.

    Wu J, Rutkowski DT, Dubois M, Swathirajan J, Saunders T, Wang J, Song B, Yau GD, Kaufman RJ. 2007. ATF6alpha Optimizes Long-Term Endoplasmic Reticulum Function to Protect Cells from Chronic Stress. Dev Cell. 13:351-64.

    Zavros Y, Waghray M, Tessier A, Bai L, Todisco A, L Gumucio D, Samuelson LC, Dlugosz A, Merchant JL. 2007. Reduced pepsin A processing of sonic hedgehog in parietal cells precedes gastric atrophy and transformation. J Biol Chem. 282:33265-33274.

    Zhu A, Sun H, Raymond RM Jr, Furie BC, Furie B, Bronstein M, Kaufman RJ, Westrick R, Ginsburg D.  2007. Fatal hemorrhage in mice lacking {gamma}-glutamyl carboxylase. Blood. 109:5270-5.

    2006
    Top Home
    Adachi M, Kurotani R, Morimura K, Shah Y, Sanford M, Madison BB, Gumucio DL, Marin HE, Peters JM, Young HA, Gonzalez FJ. 2006.
    PPAR{gamma} in colonic epithelial cells protects against experimental inflammatory bowel disease. Gut. 55:1104-13.

    Ai D, Liu W, Ma L, Dong F, Lu MF, Wang D, Verzi MP, Cai C, Gage PJ, Evans S, Black BL, Brown NA, Martin JF. 2006. Pitx2 regulates cardiac left-right asymmetry by patterning second cardiac lineage-derived myocardium. Dev Biol. 47:4905-9.

    Akimoto M, Cheng H, Zhu D; Brzezinski JA, Khanna R, Filippova E, Oh EC, Jing Y, Linares JL, Brooks M, Zareparsi S, Mears AJ, Hero A, Glaser T, Swaroop A, 2006. Targeting of GFP to newborn rods by Nrl promoter and temporal expression profiling of flow-sorted photoreceptors., Proc Natl Acad Sci U S A. 103:3890-3895.

    Albertelli MA, Scheller A, Brogley M, Robins DM. 2006. Replacing the mouse androgen receptor with human alleles demonstrates glutamine tract length-dependent effects on physiology and tumorigenesis in mice. Mol Endocrinol. 20):1248-1260.

    Cai YH, Alvarez A, Alcaide P, Duramad P, Lim YC, Jarolim P, Lowe JB, Luscinskas FW, Lichtman AH. 2006. Abrogation of functional selectin-ligand expression reduces migration of pathogenic CD8+ T cells into heart. J Immunol. 176:6568-75.

    Charles MA, Saunders TL, Wood WM, Owens K, Parlow AF, Camper SA, Ridgway EC, Gordon DF. 2006. Pituitary-specific gata2 knockout: effects on gonadotrope and thyrotrope function. Mol Endocrinol. 20:1366-1377.

    Chauhan AK, Motto DG, Lamb CB, Bergmeier W, Dockal M, Plaimauer B, Scheiflinger F, Ginsburg D, Wagner DD. 2006. Systemic antithrombotic effects of ADAMTS13. J Exp Med. 203:767-776.

    Cheng H, Aleman TS, Cideciyan AV, Khanna R, Jacobson SG, Swaroop A. 2006. In vivo function of the orphan nuclear receptor NR2E3 in establishing photoreceptor identity during mammalian retinal development. Hum Mol Genet. 15:2588-602.

    Cole JN. McArthur JD. McKay FC. Sanderson-Smith ML. Cork AJ. Ranson M. Rohde M. Itzek A. Sun H. Ginsburg D. Kotb M. Nizet V. Chhatwal GS. Walker MJ. 2006. Trigger for group A streptococcal M1T1 invasive disease.  FASEB Journal. 20:1745-1747,

    Day SM, Westfall MV, Fomicheva EV, Hoyer K, Yasuda S, La Cross NC, D'Alecy LG, Ingwall JS, Metzger JM. 2006. Histidine button engineered into cardiac troponin I protects the ischemic and failing heart. Nat Med. 12:181-189.

    Deal KK, Cantrell VA, Chandler RL, Saunders TL, Mortlock DP, Southard-Smith EM. 2006. Distant regulatory elements in a Sox10-betaGEO BAC transgene are required for expression of Sox10 in the enteric nervous system and other neural crest-derived tissues. Dev Dyn.  235:1413-1432.
    Diehl AG, Zareparsi S, Qian M, Khanna R, Angeles R, Gage PJ. 2006. Extraocular muscle morphogenesis and gene expression are regulated by Pitx2 gene dose.Invest Ophthalmol Vis Sci.47:1785-1793.

    Dobrzynski H, Billeter R, Greener ID, Tellez JO, Chandler NJ, Flagg TP, Nichols CG, Lopatin AN, Boyett MR. 2006. Expression of Kir2.1 and Kir6.2 transgenes under the control of the alpha-MHC promoter in the sinoatrial and atrioventricular nodes in transgenic mice. J Mol Cell Cardiol. J Mol Cell Cardiol. 41:855-67.

    El-Aouni C, Herbach N, Blattner SM, Henger A, Rastaldi MP, Jarad G, Miner JH, Moeller MJ, St-Arnaud R, Dedhar S, Holzman LB, Wanke R, Kretzler M. 2006.  Podocyte-specific deletion of integrin-linked kinase results in severe glomerular basement membrane alterations and progressive glomerulosclerosis. J Am Soc Nephrol. 17:1334-44.

    Ellsworth BS, Egashira N, Haller JL, Butts DL, Cocquet J, Clay CM, Osamura RY, Camper SA.  2006. FOXL2 in the Pituitary: Molecular, Genetic and Developmental Analysis. Mol Endocrinol. 20:2796-805.

    Filipiak WE, Saunders TL. 2006. Advances in transgenic rat production. Transgenic Res. 15:673-686.

    Foulkes T, Nassar MA, Lane T, Matthews EA, Baker MD, Gerke V, Okuse K, Dickenson AH, Wood JN. 2006. Deletion of annexin 2 light chain p11 in nociceptors causes deficits in somatosensory coding and pain behavior. J Neurosci. 26:10499-10507.

    Fu Y, Huang X, Zhong H, Mortensen RM, D'Alecy LG, Neubig RR. 2006. Endogenous RGS Proteins and G{alpha} Subtypes Differentially Control Muscarinic and Adenosine-Mediated Chronotropic Effects. Circ Res. 98:659-666.

    Godovikova V, Li XR, Saunders TL, Ritchie HH. 2006. A rat 8 kb dentin sialoprotein-phosphophoryn (DSP-PP) promoter directs spatial and temporal LacZ activity in mouse tissues. Dev Biol. 289:507-16.

    Grachtchouk M, Liu J, Wang A, Wei L, Bichakjian CK, Garlick J, Paulino AF, Giordano T, Dlugosz AA. 2006. Odontogenic keratocysts arise from quiescent epithelial rests and are associated with deregulated hedgehog signaling in mice and humans. Am J Pathol. 169:806-14.

    Heilig CW, Brosius FC, Cunningham C. 2006. Role for GLUT1 in diabetic glomerulosclerosis. Expert Rev Mol Med. 8:1-18.

    Hiraoka M, Abe A, Lu Y, Yang K, Han X, Gross RW, Shayman JA. 2006. Lysosomal phospholipase A2 and phospholipidosis. Mol Cell Biol. 26:6139-48.

    Huang X, Fu Y, Charbeneau RA, Saunders TL, Taylor DK, Hankenson KD, Russell MW, D'Alecy LG, Neubig RR. 2006. Pleiotropic phenotype of a genomic knock-in of an RGS-insensitive G184S Gnai2 allele. Mol Cell Biol. 26:6870-9.

    Jain RN, Samuelson LC. 2006. Differentiation of the gastric mucosa. II. Role of gastrin in gastric epithelial cell proliferation and maturation.
    Am J Physiol Gastrointest Liver Physiol. 291:G762-5.

    Jones RG, Li X, Gray PD, Kuang J, Clayton F, Samowitz WS, Madison BB, Gumucio DL, Kuwada SK. 2006. Conditional deletion of beta1 integrins in the intestinal epithelium causes a loss of Hedgehog expression, intestinal hyperplasia, and early postnatal lethality. J Cell Biol.  175:505-14.

    Kanzaki S, Beyer L, Karolyi IJ, Dolan DF, Fang Q, Probst FJ, Camper SA, Raphael Y. 2006. Transgene correction maintains normal cochlear structure and function in 6-month-old Myo15a mutant mice. Hear Res. 214:37-44.

    Law DJ, Labut EM, Adams RD, Merchant JL. 2006. An isoform of ZBP-89 predisposes the colon to colitis. Nucleic Acids Res. 34:1342-1350.

    Law DJ, Labut EM, Merchant JL. 2006.  Intestinal overexpression of ZNF148 suppresses Apc(Min)/+ neoplasia. Mamm Genome.17:999-1004.

    Lehoczky JA, Cai WW, Douglas JA, Moran JL, Beier DR, Innis JW. 2006. Description and genetic mapping of Polypodia: an X-linked dominant mouse mutant with ectopic caudal limbs and other malformations. Mamm Genome. 17:903-13.

    Levin SI, Khaliq ZM, Aman TK, Grieco TM, Kearney JA, Raman IM, Meisler MH. 2006. Impaired motor function in mice with cell-specific knockout of Na channel Scn8a (NaV1.6) in cerebellar Purkinje neurons and granule cells. J Neurophysiol. 96:785-93.

    Li B, Duysen EG, Saunders TL, Lockridge O. 2006. Production of the butyrylcholinesterase knockout mouse. J Mol Neurosci. 30:193-6.

    Li M, Ren D, Iseki M, Takaki S, Rui L. 2006. Differential Role of SH2-B and APS in Regulating Energy and Glucose Homeostasis. Endocrinology. 147:2163-2170.

    Lin J, Patel SLin J, Patel SR, Wang M, Dressler GR. 2006. The cysteine-rich domain protein KCP is a suppressor of transforming growth factor beta/activin signaling in renal epithelia. Mol Cell Biol. 26:4577-85.

    Lopez-Diaz L, Hinkle KL, Jain RN, Zavros Y, Brunkan CS, Keeley T, Eaton KA, Merchant JL, Chew CS, Samuelson LC. 2006. Parietal Cell Hyperstimulation and Autoimmune Gastritis in Cholera Toxin Transgenic Mice.  Am J Physiol Gastrointest Liver Physiol. 290:G970-979.

    Lopez-Santiago LF, Pertin M, Morisod X, Chen C, Hong S, Wiley J, Decosterd I, Isom LL. 2006. Sodium channel beta2 subunits regulate tetrodotoxin-sensitive sodium channels in small dorsal root ganglion neurons and modulate the response to pain. J Neurosci. 26:7984-94.
    Ma J, Zeng F, Schultz RM, Tseng H. 2006.  Basonuclin: a novel mammalian maternal-effect gene. Development. 133:2053-2062.

    MacLaren RE, Pearson RA, MacNeil A, Douglas RH, Salt TE, Akimoto M, Swaroop A, Sowden JC, Ali RR. 2006. Retinal repair by transplantation of photoreceptor precursors. Nature. 444:203-7.
     
    Nose Y, Kim BE, Thiele DJ. 2006. Ctr1 drives intestinal copper absorption and is essential for growth, iron metabolism, and neonatal cardiac function. Cell Metab. 4:235-44.

    Nowotschin S, Liao J, Gage PJ, Epstein JA, Campione M, Morrow BE. 2006. Tbx1 affects asymmetric cardiac morphogenesis by regulating Pitx2 in the secondary heart field. Development. 133:1565-73.

    Pasca di Magliano M, Sekine S, Ermilov A, Ferris J, Dlugosz AA, Hebrok M. 2006. Hedgehog/Ras interactions regulate early stages of pancreatic cancer. Genes Dev. 20:3161-3173.

    Raetzman LT, Wheeler BS, Ross SA, Thomas PQ, Camper SA.  2006. Persistent expression of Notch2 delays gonadotrope differentiation. Mol Endocrinol. 20:2898-90.

         <>Reiley WW, Zhang M, Jin W, Losiewicz M, Donohue KB, Norbury CC, Sun S-C. 2006.  Regulation of T cell development by the deubiquitinating enzyme CYLD. Nature Immunology 7:411 –417.

    Rosen ED, Macdougald OA. 2006. Adipocyte differentiation from the inside out. Nat Rev Mol Cell Biol. 7:885-96.

    Sarapura VD, Wood WM, Woodmansee WW, Haakinson DJ, Dowding JM, Gordon DF, Ridgway EC. 2006. Pituitary tumors arising from glycoprotein hormone alpha-subunit-deficient mice contain transcription factors and receptors present in thyrotropes. Pituitary. 9:1-8.

  • Schreiber T, Ehlers S, Aly S, Holscher A, Hartmann S, Lipp M, Lowe JB, Holscher C. 2006. Selectin ligand-independent priming and maintenance of T cell immunity during airborne tuberculosis. J Immunol. 176:1131-1140.

    Sclafani AM, Skidmore JM, Ramaprakash H, Trumpp A, Gage PJ, Martin DM. 2006. Nestin-Cre mediated deletion of Pitx2 in the mouse. Genesis. 44:336-44.

    Shen Y, Bodary PF, Vargas FB, Homeister JW, Gordon D, Ostenso KA, Shayman JA, Eitzman DT. 2006. Alpha-galactosidase A deficiency leads to increased tissue fibrin deposition and thrombosis in mice homozygous for the factor V Leiden mutation. Stroke. 37:1106-1108.
    Simeone DM, Zhang L, Treutelaar MK, Zhang L, Graziano K, Logsdon CD, Burant CF. 2006. Islet Hypertrophy Following Pancreatic Disruption of Smad4 Signaling. Am J Physiol Endocrinol Metab. 291:E12305-16.

    St John JA, Claxton C, Robinson MW, Yamamoto F, Domino SE, Key B. 2006. Genetic manipulation of blood group carbohydrates alters development and pathfinding of primary sensory axons of the olfactory systems. Dev Biol. 298:470-84.

    Wang SH. Arscott P. Wu P. Baker JR Jr. 2006. No apparent damage in the thyroid of transgenic mice expressing antiapoptotic FLIP. Thyroid. 16:1-8,

    Westphal NJ, Seasholtz AF. 2006. CRH-BP: the regulation and function of a phylogenetically conserved binding protein. Front Biosci.11:1878-91.

    Wilkinson Iv J, Di X, Schonig K, Buss JL, Kock ND, Cline JM, Saunders TL, Bujard H, Torti SV, Torti FM. 2006. Tissue-specific expression of ferritin H regulates cellular iron homeostasis in vivo. Biochem J. 395:501-507.

    Williams ME, Lehoczky JA, Innis JW. 2006. A group 13 homeodomain is neither necessary nor sufficient for posterior prevalence in the mouse limb. Dev Biol. 297:493-507.

    Woodruff-Pak DS, Green JT, Levin SI, Meisler MH. 2006. Inactivation of sodium channel Scn8A (Na-sub(v)1.6) in Purkinje neurons impairs learning in Morris water maze and delay but not trace eyeblink classical conditioning. Behav Neurosci. 120:229-240.

    Xiang J, Chiang PP, Hu Y, Smith DE, Keep RF. 2006. Role of PEPT2 in glycylsarcosine transport in astrocyte and glioma cultures. Neurosci Lett. 396:225-9.

    Xiang J, Hu Y, Smith DE, Keep RF. 2006. PEPT2-mediated transport of 5-aminolevulinic acid and carnosine in astrocytes. Brain Res. 1122:18-23.

    Yu Z, Dadgar N, Albertelli M, Gruis K, Jordan C, Robins DM, Lieberman AP. 2006. Androgen-dependent pathology demonstrates myopathic contribution to the Kennedy disease phenotype in a mouse knock-in model. J Clin Invest. 116:2663-72.

    Yu Z, Dadgar N, Albertelli M, Scheller A, Albin RL, Robins DM, Lieberman AP. 2006. Abnormalities of Germ Cell Maturation and Sertoli Cell Cytoskeleton in Androgen Receptor 113 CAG Knock-In Mice Reveal Toxic Effects of the Mutant Protein.  Am J Pathol. 168:195-204.
    Zhang HZ, Degar BA, Rogoulina S, Resor C, Booth CJ, Sinning J, Gage PJ, Forget BG. 2006. Hematopoiesis following disruption of the Pitx2 homeodomain gene. Exp Hematol. 34:167-78.
    Zhang K, Shen X, Wu J, Sakaki K, Saunders T, Rutkowski DT, Back SH, Kaufman RJ. 2006. Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response. Cell. 124:587-599.
    Zhu M, Lovell KL, Patterson JS, Saunders TL, Hughes ED, Friderici KH. 2006. {beta}-Mannosidosis mice: a model for the human lysosomal storage disease. Hum Mol Genet. 15:493-500.

    2005


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    Bennett CN, Longo KA, Wright WS, Suva LJ, Lane TF, Hankenson KD, MacDougald OA. 2005. Regulation of osteoblastogenesis and bone mass by Wnt10b. Proc Natl Acad Sci U S A. 102:3324-3329.

    Brzezinski JA 4th, Brown NL, Tanikawa A, Bush RA, Sieving PA, Vitaterna MH, Takahashi JS, Glaser T. 2005. Loss of circadian photoentrainment and abnormal retinal electrophysiology in math5 mutant mice.  Invest Ophthalmol Vis Sci. 46:2540-2551.

    Charles MA, Suh H, Hjalt TA, Drouin J, Camper SA, Gage PJ. 2005.  PITX genes are required for cell survival and Lhx3 activation. Mol Endocrinol.  19:1893-903.

    Daniele LL, Lillo C, Lyubarsky AL, Nikonov SS, Philp N, Mears AJ, Swaroop A, Williams DS, Pugh EN Jr. 2005. Cone-like morphological, molecular, and electrophysiological features of the photoreceptors of the Nrl knockout mouse. Invest Ophthalmol Vis Sci.46:2156-67.

    Dunnick WA, Shi J, Graves KA, Collins JT. 2005. The 3' end of the heavy chain constant region locus enhances germline transcription and switch recombination of the four gamma genes. J Exp Med. 201:1459-66.

    Eitzman DT, Westrick RJ, Shen Y, Bodary PF, Gu S, Manning SL, Dobies SL, Ginsburg D. 2005. Homozygosity for Factor V Leiden Leads to Enhanced Thrombosis and Atherosclerosis in Mice. Circulation. 111:1822-5.
    Evans AL, Gage PJ. 2005. Expression of the homeobox gene Pitx2 in neural crest is required for optic stalk and ocular anterior segment development. Hum Mol Genet. 15:3347-3359.

    Flagg TP, Remedi MS, Masia R, Gomes J, McLerie M, Lopatin AN, Nichols CG. 2005.  Transgenic overexpression of SUR1 in the heart suppresses sarcolemmal K(ATP). J Mol Cell Cardiol. 39:647-56.

    Gage PJ, Rhoades W, Prucka SK, Hjalt T. 2005. Fate maps of neural crest and mesoderm in the mammalian eye. Invest Ophthalmol Vis Sci. 46:4200-8.

    Ginsburg D. 2005. Identifying novel genetic determinants of hemostatic balance. J Thromb Haemost. 8:1561-8.

    Hammer GD, Parker KL, Schimmer BP. 2005.  Minireview: transcriptional regulation of adrenocortical development. Endocrinology.146:1018-24.

    Hurd EA, Holmen JM, Hansson GC, Domino SE. 2005. Gastrointestinal Mucins of Fut2-Null Mice Lack Terminal Fucosylation without Affecting Colonization by Candida albicans. Glycobiology. 15:1002-1007.

    Hutchin ME, Kariapper MS, Grachtchouk M, Wang A, Wei L, Cummings D, Liu J, Michael LE, Glick A, Dlugosz AA. 2005. Sustained Hedgehog signaling is required for basal cell carcinoma proliferation and survival: conditional skin tumorigenesis recapitulates the hair growth cycle. Genes Dev. 19:214-223.

    Jain RN, Brunkan CS, Chew CS, Samuelson LC. 2005. Gene Expression Profiling of Gastrin Target Genes in Parietal Cells. Physiol Genomics. 24:124-32

    Kang S, Bajnok L, Longo KA, Petersen RK, Hansen JB, Kristiansen K, MacDougald OA. 2005. Effects of Wnt signaling on brown adipocyte differentiation and metabolism mediated by PGC-1alpha. Mol Cell Biol. 25:1272-82. 

    Kang W, Rathinavelu S, Samuelson LC, Merchant JL. 2005. Interferon gamma induction of gastric mucous neck cell hypertrophy. Lab Invest. 85:702-715.

    Keegan CE, Hutz JE, Else T, Adamska M, Shah SP, Kent AE, Howes JM, Beamer WG, Hammer GD. 2005. Urogenital and caudal dysgenesis in adrenocortical dysplasia (acd) mice is caused by a splicing mutation in a novel telomeric regulator. Hum Mol Genet. 14:113-23.

    Kieusseian A, Chagraoui J, Kerdudo C, Mangeot PE, Gage PJ, Navarro N, Izac B, Uzan G, Forget BG, Dubart-Kupperschmitt A. 2005. Expression of Pitx2 in stromal cells is required for normal hematopoiesis. Blood. 107:492-500.

    Kurachi K, Kurachi S. 2005. Molecular mechanisms of age-related regulation of genes. J Thromb Haemost. 3:909-914.

    Lay JM, Bane G, Brunkan CS, Davis J, Lopez-Diaz L, Samuelson LC. 2005.  Enteroendocrine cell expression of a cholecystokinin gene construct in transgenic mice and cultured cells. Am J Physiol Gastrointest Liver Physiol. 288:G354-61.

    Lin J, Patel SR, Cheng X, Cho EA, Levitan I, Ullenbruch M, Phan SH, Park JM, Dressler GR. 2005. Kielin/chordin-like protein, a novel enhancer of BMP signaling, attenuates renal fibrotic disease. Nat Med. 11:387-93.

    Madison BB, Braunstein K, Kuizon E, Portman K, Qiao XT, Gumucio DL. 2005. Epithelial hedgehog signals pattern the intestinal crypt-villus axis. Development. 132:279-89.

    McEwen E, Kedersha N, Song B, Scheuner D, Gilks N, Han A, Chen JJ, Anderson P, Kaufman RJ. 2005. Heme-regulated inhibitor kinase-mediated phosphorylation of eukaryotic translation initiation factor 2 inhibits translation, induces stress granule formation, and mediates survival upon arsenite exposure. J Biol Chem. 280:16925-33.

    McInerney GM, Kedersha NL, Kaufman RJ, Anderson P, Liljestrom P. 2005. Importance of eIF2alpha phosphorylation and stress granule assembly in alphavirus translation regulation. Mol Biol Cell. 16:3753-63.

    Meadows LS, Isom LL. 2005. Sodium channels as macromolecular complexes: Implications for inherited arrhythmia syndromes.  Cardiovasc Res. 67:448-58.

    Meehan TP, Harmon BG, Overcast ME, Yu KK, Camper SA, Puett D, Narayan P. 2005. Gonadal defects and hormonal alterations in transgenic mice expressing a single chain human chorionic gonadotropin-lutropin receptor complex. J Mol Endocrinol. 34:489-503.

    Moeller MJ, Soofi A, Sanden SK, Floege J, Kriz W, Holzman LB. 2005.  An efficient system for tissue-specific over-expression of transgenes in podocytes in vivo. Am J Physiol Renal Physiol.  289:F481-8.

    Molinari M, Galli C, Vanoni O, Arnold SM, Kaufman RJ. 2005. Persistent glycoprotein misfolding activates the glucosidase II/UGT1-driven calnexin cycle to delay aggregation and loss of folding competence. Mol Cell. 20:503-12.

    Motto DG, Chauhan AK, Zhu G, Homeister J, Lamb CB, Desch KC, Zhang W, Tsai HM, Wagner DD, Ginsburg D. 2005. Shigatoxin triggers thrombotic thrombocytopenic purpura in genetically susceptible ADAMTS13-deficient mice.  J Clin Invest. 115:2752-61.

    Nabulsi NB, Smith DE, Kilbourn MR. 2005. [(11)C]Glycylsarcosine: synthesis and in vivo evaluation as a PET tracer of PepT2 transporter function in kidney of PepT2 null and wild-type mice. Bioorg Med Chem. 13:2993-3001.

    Nikonov SS, Daniele LL, Zhu X, Craft CM, Swaroop A, Pugh EN Jr. 2005. Photoreceptors of Nrl -/- mice coexpress functional S- and M-cone opsins having distinct inactivation mechanisms. J Gen Physiol. 125:287-304.

    Ocheltree SM, Shen H, Hu Y, Keep RF, Smith DE. 2005. Role and relevance of peptide transporter 2 (PEPT2) in the kidney and choroid plexus: in vivo studies with glycylsarcosine in wild-type and PEPT2 knockout mice. J Pharmacol Exp Ther. 31:240-7.

    Park SY, Meeks JJ, Raverot G, Pfaff LE, Weiss J, Hammer GD, Jameson JL. 2005. Nuclear receptors Sf1 and Dax1 function cooperatively to mediate somatic cell differentiation during testis development. Development. 132:2415-23.

    Piccio L, Rossi B, Colantonio L, Grenningloh R, Gho A, Ottoboni L, Homeister JW, Scarpini E, Martinello M, Laudanna C, D'Ambrosio D, Lowe JB, Constantin G. 2005. Efficient recruitment of lymphocytes in inflamed brain venules requires expression of cutaneous lymphocyte antigen and fucosyltransferase-VII. J Immunol. 174:5805-13.

    Ren D, Li M, Duan C, Rui L.2005. Identification of SH2-B as a key regulator of leptin sensitivity, energy balance, and body weight in mice.
    Cell Metab. 2:95-104.

    Rieder G, Tessier AJ, Qiao XT, Madison B, Gumucio DL, Merchant JL. 2005. Helicobacter-induced intestinal metaplasia in the stomach correlates with Elk-1 and serum response factor induction of villin. J Biol Chem. 280:4906-12.

    Satoh T, Kanai Y, Wu MH, Yokozeki H, Kannagi R, Lowe JB, Nishioka K. 2005. Synthesis of {alpha}(1,3) Fucosyltransferases IV- and VII-Dependent Eosinophil Selectin Ligand and Recruitment to the Skin. Am J Pathol. 167:787-96.

    Scheuner D, Mierde DV, Song B, Flamez D, Creemers JW, Tsukamoto K, Ribick M, Schuit FC, Kaufman RJ. 2005. Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis. Nat Med. 11:757-64.

    Seong E, Wainer BH, Hughes ED, Saunders TL, Burmeister M, Faundez V. 2005. Genetic analysis of the neuronal and ubiquitous AP-3 adaptor complexes reveals divergent functions in brain. Mol Biol Cell. 16:128-40.

    Shen H, Keep RF, Hu Y, Smith DE. 2005. PEPT2 (Slc15a2)-Mediated Unidirectional Transport of Cefadroxil from Cerebrospinal Fluid into Choroid Plexus. J Pharmacol Exp Ther. 315:1101-8.

    Siegmund K, Feuerer M, Siewert C, Ghani S, Haubold U, Dankof A, Krenn V, Schon MP, Scheffold A, Lowe JB, Hamann A, Syrbe U, Huehn J. 2005. Migration matters: regulatory T-cell compartmentalization determines suppressive activity in vivo. Blood. 106:3097-104.

    van den Buuse M, van Driel IR, Samuelson LC, Pijnappel M, Martin S. 2005. Reduced effects of amphetamine on prepulse inhibition of startle in gastrin-deficient mice. Neurosci Lett. 373:237-42.

    Vesper AH, Raetzman LT, Camper SA. 2005. Role of PROP1 in gonadotrope differentiation and puberty. Endocrinology. 147:1654-1663.

    Ward RD, Raetzman LT, Suh H, Stone BM, Nasonkin IO, Camper SA. 2005. Role of PROP1 in pituitary gland growth. Mol Endocrinol.
    19:698-710.

    Wharram BL, Goyal M, Wiggins JE, Sanden SK, Hussain S, Filipiak WE, Saunders TL, Dysko RC, Kohno K, Holzman LB, Wiggins RC. 2005.  Podocyte Depletion Causes Glomerulosclerosis: Diphtheria Toxin-Induced Podocyte Depletion in Rats Expressing Human Diphtheria Toxin Receptor Transgene. J Am Soc Nephrol. J Am Soc Nephrol.16:2941-52.

    Xiang J, Chiang PP, Hu Y, Smith DE, Keep RF. 2005. Role of PEPT2 in glycylsarcosine transport in astrocyte and glioma cultures. Neurosci Lett. 396:225-9.

    Zavros Y, Eaton KA, Kang W, Rathinavelu S, Katukuri V, Kao JY, Samuelson LC, Merchant JL. 2005. Chronic gastritis in the hypochlorhydric gastrin-deficient mouse progresses to adenocarcinoma. Oncogene. 24:2354-66.

    Zhang K, Wong HN, Song B, Miller CN, Scheuner D, Kaufman RJ. 2005.  The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis. J Clin Invest. 115:268-81.

    2004
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    Adamska M, MacDonald BT, Sarmast ZH, Oliver ER, Meisler MH. 2004. En1 and Wnt7a interact with Dkk1 during limb development in the mouse. Dev Biol.272:134-44.

    Akimoto M, Filippova E, Gage PJ, Zhu X, Craft CM, Swaroop A. 2004 Transgenic mice expressing Cre-recombinase specifically in M- or S-cone photoreceptors. Invest Ophthalmol Vis Sci.45:42-7.

    Berton MT, Linehan LA, Wick KR, Dunnick WA. 2004.  NF-kappaB elements associated with the Stat6 site in the germline gamma1 immunoglobulin promoter are not necessary for the transcriptional response to CD40 ligand. Int Immunol. 16:1741-9.

    Chen C, Westenbroek RE, Xu X, Edwards CA, Sorenson DR, Chen Y, McEwen DP, O'Malley HA, Bharucha V, Meadows LS, Knudsen GA, Vilaythong A, Noebels JL, Saunders TL, Scheuer T, Shrager P, Catterall WA, Isom LL. 2004. Mice lacking sodium channel beta1 subunits display defects in neuronal excitability, sodium channel expression, and nodal architecture. J Neurosci. 24:4030-42.

    Chen D, Zhao CM, Hakanson R, Samuelson LC, Rehfeld JF, Friis-Hansen L. 2004. Altered control of gastric acid secretion in gastrin-cholecystokinin double mutant mice. Gastroenterology. 2004 126:476-87.

    Dang L, Pulukuri S, Mears AJ, Swaroop A, Reese BE, Sitaramayya A.. 2004. Connexin 36 in photoreceptor cells: studies on transgenic rod-less and cone-less mouse  retinas. Mol Vis. 10:323-7.

    Davis TH, Chen C, Isom LL. 2004. Sodium channel beta1 subunits promote neurite outgrowth in cerebellar granule neurons. J Biol Chem. 279:51424-32.

    Domino SE, Hurd EA. 2004. LacZ expression in Fut2-LacZ reporter mice reveals estrogen-regulated endocervical glandular expression during estrous cycle, hormone replacement, and pregnancy. Glycobiology. 14:169-75.

    Duan C, Yang H, White MF, Rui L. 2004. Disruption of the SH2-B gene causes age-dependent insulin resistance and glucose intolerance.
    Mol Cell Biol. 17:7435-43.

    Dunnick WA, Shi J, Graves KA, Collins JT. 2004. Germline transcription and switch recombination of a transgene containing the entire H chain constant region locus: effect of a mutation in a STAT6 binding site in the gamma 1 promoter. J Immunol.  Nov 1;173(9):5531-9.

    Franic TV, Judd LM, Nguyen NV, Samuelson LC, Loveland KL, Giraud AS, Gleeson PA, Van Driel IR. 2004. Growth factors associated with gastric mucosal hypertrophy in autoimmune gastritis. Am J Physiol Gastrointest Liver Physiol.  287:G910-8.

    Fu Y, Zhong H, Nanamori M, Mortensen RM, Huang X, Lan K, Neubig RR. 2004. RGS-insensitive G-protein mutations to study the role of endogenous RGS proteins. Methods Enzymol. 389:229-43

    Homeister JW, Daugherty A, Lowe JB. 2004. {alpha}(1,3)Fucosyltransferases FucT-IV and FucT-VII Control Susceptibility to Atherosclerosis in Apolipoprotein E-/- Mice. Arterioscler Thromb Vasc Biol. 24:1897-903.

    Hurd, EA., Domino, SE. 2004 Increased susceptibility of secretor factor gene Fut2-null mice to experimental vaginal candidiasis. Infect Immun. 72:4279-81.

    Hyun TS, Li L, Oravecz-Wilson KI, Bradley SV, Provot MM, Munaco AJ, Mizukami IF, Sun H, Ross TS. 2004. Hip1-related mutant mice grow and develop normally but have accelerated spinal abnormalities and dwarfism in the absence of HIP1. Mol Cell Biol. 24:4329-40.

    Imaizumi K, Benito A, Kiryu-Seo S, Gonzalez V, Inohara N, Leiberman AP, Kiyama H, Nunez G. 2004. Critical role for DP5/Harakiri, a Bcl-2 homology domain 3-only Bcl-2 family member, in axotomy-induced neuronal cell death. J Neurosci. 24:3721-5.

    Iwamori M, Domino SE. 2004. Tissue-specific loss of fucosylated glycolipids in mice with targeted deletion of alpha(1,2)fucosyltransferase genes.
    Biochem J.380:75-81.

    Jiang D, Franceschi RT, Boules H, Xiao G. 2004. Parathyroid hormone induction of the osteocalcin gene. Requirement for an osteoblast-specific element 1 sequence in the promoter and involvement of multiple-signaling pathways. J Biol Chem. 279:5329-37.

    Kaur S, Norkina O, Ziemer D, Samuelson LC, De Lisle RC. 2004. Acidic duodenal pH alters gene expression in the cystic fibrosis mouse pancreas. Am J Physiol Gastrointest Liver Physiol. 287:G480-90.

    Kubisch C, Dimagno MJ, Tietz AB, Welsh MJ, Ernst SA, Brandt-Nedelev B, Diebold J, Wagner AC, Goke B, Williams JA, Schafer C. 2004. Overexpression of heat shock protein Hsp27 protects against cerulein-induced pancreatitis. Gastroenterology.  127:275-86.

    Lehoczky JA, Williams ME, Innis JW. 2004. Conserved expression domains for genes upstream and within the HoxA and HoxD clusters suggests a long-range enhancer existed before cluster duplication. Evol Dev. 6:423-30.

    Levin SI, Meisler MH. 2004. Floxed allele for conditional inactivation of the voltage-gated sodium channel Scn8a (Na(v)1.6). Genesis. 2004 39:234-9.

    Li J, McLerie M, Lopatin AN. 2004. Transgenic Up-Regulation of IK1 in The Mouse Heart Leads to Multiple Abnormalities of Cardiac Excitability. Am J Physiol Heart Circ Physiol. 287:H2790-80.

    Longo KA, Wright WS, Kang S, Gerin I, Chiang SH, Lucas PC, Opp MR, MacDougald OA. Wnt10b inhibits development of white and brown adipose tissues. J Biol Chem.  2004 Aug 20;279(34):35503-9.

    MacDonald BT, Adamska M, Meisler MH. 2004. Hypomorphic expression of Dkk1 in the doubleridge mouse: dose dependence and compensatory interactions with Lrp6. Development. 131:2543-52.

    Martin DM, Skidmore JM, Philips ST, Vieira C, Gage PJ, Condie BG, Raphael Y, Martinez S, Camper SA. 2004. PITX2 is required for normal development of neurons in the mouse subthalamic nucleus and midbrain. Dev Biol. 267:93-108.

    Martins RP, Ostermeier GC, Krawetz SA. 2004. Nuclear matrix interactions at the human protamine domain: a working model of potentiation. J Biol Chem. 279:51862-8.

    Moeller MJ, Soofi A, Hartmann I, Le Hir M, Wiggins R, Kriz W, Holzman LB. 2004. Podocytes populate cellular crescents in a murine model of inflammatory  glomerulonephritis. J Am Soc Nephrol.15:61-7.

    Nasonkin IO, Ward RD, Raetzman LT, Seasholtz AF, Saunders TL, Gillespie PJ, Camper SA. Pituitary hypoplasia and respiratory distress syndrome in Prop1 knockout mice. Hum Mol Genet. 2004 Nov 15;13(22):2727-35.

    Ocheltree SM, Shen H, Hu Y, Xiang J, Keep RF, Smith DE. 2004. Mechanisms of cefadroxil uptake in the choroid plexus: studies in wild-type and PEPT2 knockout mice. J Pharmacol Exp Ther.308:462-7.

    Ocheltree SM, Shen H, Hu Y, Xiang J, Keep RF, Smith DE. 2004. Role of PEPT2 in the choroid plexus uptake of glycylsarcosine and 5-aminolevulinic acid: studies in wild-type and null mice. Pharm Res. 21:1680-5.

    Oliver ER, Saunders TL, Tarle SA, Glaser T. 2004. Ribosomal protein L24 defect in Belly spot and tail (Bst), a mouse Minute. Development. 131:3907-20.

    Oravecz-Wilson KI, Kiel MJ, Li L, Rao DS, Saint-Dic D, Kumar PD, Provot MM, Hankenson KD, Reddy VN, Lieberman AP, Morrison SJ, Ross TS. 2004. Huntingtin Interacting Protein 1 mutations lead to abnormal hematopoiesis, spinal defects and cataracts. Hum Mol Genet. 13:851-67.

    Patel SR, Dressler GR. 2004. Expression of Pax2 in the intermediate mesoderm is regulated by YY1. Dev Biol. 267:505-16.

    Parker AC, Mundada LV, Schmaier AH, Fay WP. 2004. Factor V Leiden inhibits fibrinolysis in vivo. Circulation. 110:3594-8.

    Pittler SJ, Zhang Y, Chen S, Mears AJ, Zack DJ, Ren Z, Swain PK, Yao S, Swaroop A, White JB. 2004. Functional analysis of the rod photoreceptor cGMP phosphodiesterase alpha-subunit gene promoter: Nrl and Crx are required for full transcriptional activity. J Biol Chem. 179:19800-7.

    Raetzman LT, Ross SA, Cook S, Dunwoodie SL, Camper SA, Thomas PQ. 2004. Developmental regulation of Notch signaling genes in the embryonic pituitary: Prop1 deficiency affects Notch2 expression. Dev Biol.265:329-40.

    Sun H, Ringdahl U, Homeister JW, Fay WP, Engleberg NC, Yang AY, Rozek LS, Wang X, Sjobring U, Ginsburg D. 2004. Plasminogen is a critical host pathogenicity factor for group A streptococcal infection. Science. 305:1283-6.

    Seong E, Saunders TL, Stewart CL, Burmeister M.2004. To knockout in 129 or in C57BL/6: that is the question. Trends Genet. 20:59-62.

    Strettoi E, Mears AJ, Swaroop A. 2004. Recruitment of the rod pathway by cones in the absence of rods. J Neurosci. 24:7576-82.

    Teuscher NS, Shen H, Shu C, Xiang J, Keep RF, Smith DE. 2004. Carnosine uptake in rat choroid plexus primary cell cultures and choroid plexus whole tissue from PEPT2 null mice. J Neurochem. 91:1024.

    Teuscher NS, Shen H, Shu C, Xiang J, Keep RF, Smith DE. 2004. Carnosine uptake in rat choroid plexus primary cell cultures and choroid plexus whole tissue from PEPT2 null mice. J Neurochem. 89:375-82.

    Van Keuren ML, Saunders TL. 2004.Rederivation of Transgenic and Gene-Targeted Mice by Embryo Transfer. Transgenic Res. 13:363-371.

    Wang Y, Boeck AT, Duysen EG, Van Keuren M, Saunders TL, Lockridge O. 2004. Resistance to organophosphorus agent toxicity in transgenic mice expressing the G117H mutant of human butyrylcholinesterase. Toxicol Appl Pharmacol. 196:356-66.

    Wei Q, Lu XY, Liu L, Schafer G, Shieh KR, Burke S, Robinson TE, Watson SJ, Seasholtz AF, Akil H. 2004.Glucocorticoid receptor overexpression in forebrain: a mouse model of increased emotional lability. Proc Natl Acad Sci U S A. 101:11851-6.

    2003
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    Adamska M, MacDonald BT, Meisler MH. 2004. Doubleridge, a mouse mutant with defective compaction of the apical ectodermal ridge and normal dorsal-ventral patterning of the limb. Dev Biol. 2003 Mar 15;255(2):350-62.

    Ameri A, Kurachi S, Sueishi K, Kuwahara M, Kurachi K. 2003. Myocardial fibrosis in mice with overexpression of human blood coagulation factor IX. Blood. 101(5):1871-3.

    Becker DJ, Myers JT, Ruff MM, Smith PL, Gillespie BW, Ginsburg DW, Lowe JB. 2003. Strain-specific modification of lethality in fucose-deficient mice. Mamm Genome. 14:130-9.

    Ben-Yosef T, Belyantseva IA, Saunders TL, Hughes ED, Kawamoto K, Van Itallie CM, Beyer LA, Halsey K, Gardner DJ, Wilcox ER, Rasmussen J, Anderson JM, Dolan DF, Forge A, Raphael Y, Camper SA, Friedman TB. 2003. Claudin 14 knockout mice, a model for autosomal recessive deafness DFNB29, are deaf due to cochlear hair cell degeneration. Hum Mol Genet. 12(16):2049-2061.

    Cho EA, Prindle MJ, Dressler GR. 2003. BRCT domain-containing protein PTIP is essential for progression through mitosis. Mol Cell Biol. 23:1666-73.

    Gopalakrishnan R, Thomas PE, Benson MD, Wang D, Franceschi RT. 2003. A homeodomain protein binding element in the bone sialoprotein promoter is critical for tissue-specific expression in bone. Connect Tissue Res. 44:154-60.

    Grachtchouk V, Grachtchouk M, Lowe L, Johnson T, Wei L, Wang A, de Sauvage F, Dlugosz AA. 2003 The magnitude of hedgehog signaling activity defines skin tumor phenotype.EMBO J. 22:2741-51.

    Heilig CW, Saunders T, Brosius FC 3rd, Moley K, Heilig K, Baggs R, Guo L, Conner D.2003. Glucose transporter-1-deficient mice exhibit impaired development and deformities that are similar to diabetic embryopathy. Proc Natl Acad Sci U S A.100:15613-8. 

    Hinkle KL, Bane GC, Jazayeri A, Samuelson LC. 2003. Enhanced calcium signaling and acid secretion in parietal cells isolated from gastrin-deficient mice. Am J Physiol Gastrointest Liver Physiol. 284(1):G145-53.

    Jahroudi N, Schmaier A, Srikanth S, Mahdi F, Lutka FA, Bowser R. 2003. Von Willebrand factor promoter targets the expression of amyloid beta protein precursor to brain vascular endothelial cells of transgenic mice. J Alzheimers Dis. 5:149-58.

    Jones JM, Datta P, Srinivasula SM, Ji W, Gupta S, Zhang Z, Davies E, Hajnoczky G, Saunders TL, Van Keuren ML, Fernandes-Alnemri T, Meisler MH, Alnemri ES. 2003. Nature. 425:721-7.

    Krebs CJ, Larkins LK, Price R, Tullis KM, Miller RD, Robins DM. 2003. Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression. Genes Dev.17:2664-74.

    Marcil A, Dumontier E, Chamberland M, Camper SA, Drouin J.2003. Pitx1 and Pitx2 are required for development of hindlimb buds. Development. 130:45-55.

    McLerie M, Lopatin A.2003. Dominant-negative suppression of I(K1) in the mouse heart leads to altered cardiac excitability. J Mol Cell Cardiol. 35:367-78.

    Mill P, Mo R, Fu H, Grachtchouk M, Kim PC, Dlugosz AA, Hui CC. 2003. Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development. Genes Dev. 17:282-94.

    Moeller MJ, Sanden SK, Soofi A, Wiggins RC, Holzman LB. 2003. Podocyte-specific expression of cre recombinase in transgenic mice. Genesis. 2003 Jan;35(1):39-42.

    Norman LP, Jiang W, Han X, Saunders TL, Bond JS. 2003. Targeted disruption of the meprin Beta gene in mice leads to underrepresentation of knockout mice and changes in renal gene expression profiles. Mol Cell Biol. Feb;23(4):1221-30.

    Samuelson LC, Hinkle KL. 2003. Insights into the regulation of gastric Acid secretion through analysis of genetically engineered mice. Annu Rev Physiol. 65:383-400.

    Saunders TL. 2003. Reporter molecules in genetically engineered mice. Methods Mol Biol.209:125-43.

    Shen H, Smith DE, Keep RF, Xiang J, Brosius FC 3rd. 2003. Targeted disruption of the PEPT2 gene markedly reduces dipeptide uptake in choroid plexus. J Biol Chem. 278(7):4786-91.

    Shigehara T, Zaragoza C, Kitiyakara C, Takahashi H, Lu H, Moeller M, Holzman LB, Kopp JB. 2003. Inducible podocyte-specific gene expression in transgenic mice. J Am Soc Nephrol. 14:1998-2003.

    Sun FJ, Kaur S, Ziemer D, Banerjee S, Samuelson LC, De Lisle RC. 2003. Decreased gastric bacterial killing and up-regulation of protective genes in small intestine in gastrin-deficient mouse. Dig Dis Sci. 48:976-85.

    Sun H, Yang TL, Yang A, Wang X, Ginsburg D. 2003. The murine platelet and plasma factor V pools are biosynthetically distinct and sufficient for minimal hemostasis. Blood. 102:2856-61.

    Swain JE, Wang X, Saunders TL, Dunn R, Smith GD. 2003. Specific inhibition of mouse oocyte nuclear protein phosphatase-1 stimulates germinal vesicle breakdown. Mol Reprod Dev. 65:96-103.

    Van Mater D, Kolligs FT, Dlugosz AA, Fearon ER. 2003. Transient activation of beta -catenin signaling in cutaneous keratinocytes is sufficient to trigger the active growth phase of the hair cycle in mice. Genes Dev. 17:1219-24.

    Yang TL, Pipe SW, Yang A, Ginsburg D. 2003. Biosynthetic origin and functional significance of murine platelet factor V. Blood.102:2851-5.

    2002
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    Babu PS, Bavers DL, Beuschlein F, Shah S, Jeffs B, Jameson JL, Hammer GD. 2002. Interaction between Dax-1 and steroidogenic factor-1 in vivo: increased adrenal responsiveness to ACTH in the absence of Dax-1.  Endocrinology. Feb;143(2):665-73.

    Braunstein EM, Qiao XT, Madison B, Pinson K, Dunbar L, Gumucio DL. 2002. Villin: A marker for development of the epithelial pyloric border.  Dev Dyn. 224:90-102.

    Chen C, Bharucha V, Chen Y, Westenbroek RE, Brown A, Malhotra JD, Jones D, Avery C, Gillespie PJ 3rd, Kazen-Gillespie KA, Kazarinova-Noyes K, Shrager P, Saunders TL, Macdonald RL, Ransom BR, Scheuer T, Catterall WA, Isom LL. 2002. Reduced sodium channel density, altered voltage dependence of inactivation, and increased susceptibility to seizures in mice lacking sodium channel beta 2-subunits. Proc Natl Acad Sci U S A.  Dec 24;99(26):17072-7.

    Eitzman DT, Westrick RJ, Bi X, Manning SL, Wilkinson JE, Broze GJ, Ginsburg D. 2002. Lethal perinatal thrombosis in mice resulting from the interaction of tissue factor pathway inhibitor deficiency and factor V Leiden. Circulation. May 7;105(18):2139-42.

    Erdmann I, Scheidegger EP, Koch FK, Heinzerling L, Odermatt B, Burg G, Lowe JB, Kundig TM. 2002. Fucosyltransferase VII-deficient mice with defective E-, P-, and L-selectin ligands show impaired CD4+ and CD8+ T cell migration into the skin, but normal extravasation into visceral organs. J Immunol. Mar 1;168(5):2139-46.

    Innis JW, Margulies EH, Kardia S. 2002. Integrative biology and the developing limb bud. Evol Dev. 4:378-89.

    Ishida S, Lee J, Thiele DJ, Herskowitz I. 2002. Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals. Proc Natl Acad Sci U S A. 99(22):14298-302.

    Lee K, Tirasophon W, Shen X, Michalak M, Prywes R, Okada T, Yoshida H, Mori K, Kaufman RJ. 2002. IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response. Genes Dev. 16:452-66.

    Lee J, Petris MJ, Thiele DJ. 2002. Characterization of mouse embryonic cells deficient in the Ctr1 high affinity copper transporter: Identification of a Ctr1-independent copper system. J Biol Chem. 277:40253-9.

    Madison BB, Dunbar L, Qiao XT, Braunstein KA, Braunstein EM, Gumucio DL. 2002. Cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine. J Biol Chem. J Biol Chem. 277(36):33275-83.

    Martin DM, Skidmore JM, Fox SE, Gage PJ, Camper SA.2002. Pitx2 distinguishes subtypes of terminally differentiated neurons in the developing mouse neuroepithelium. Dev Biol. 252:84-99.

    Michele DE, Gomez CA, Hong KE, Westfall MV, Metzger JM. 2002. Cardiac dysfunction in hypertrophic cardiomyopathy mutant tropomyosin mice is transgene-dependent, hypertrophy-independent, and improved by beta-blockade. Circ Res. 91(3):255-62.

    Moeller MJ, Sanden SK, Soofi A, Wiggins RC, Holzman LB. 2002. Two Gene Fragments that Direct Podocyte-Specific Expression in Transgenic Mice. J Am Soc Nephrol. Jun;13(6):1561-7.

    Pendl GG, Robert C, Steinert M, Thanos R, Eytner R, Borges E, Wild MK, Lowe JB, Fuhlbrigge RC, Kupper TS, Vestweber D, Grabbe S. Immature mouse dendritic cells enter inflamed tissue, a process that requires E- and P-selectin, but not P-selectin glycoprotein ligand 1. Blood. 2002 Feb 1;99(3):946-56.

    Peng L, Bhatia N, Parker AC, Zhu Y, Fay WP. 2002. Endogenous vitronectin and plasminogen activator inhibitor-1 promote neointima formation in murine carotid arteries. Arterioscler Thromb Vasc Biol. 22(6):934-9.

    Raetzman LT, Ward R, Camper SA. 2002. Lhx4 and Prop1 are required for cell survival and expansion of the pituitary primordia. Development. 129:4229-39.

    Sheng H, Goich S, Wang A, Grachtchouk M, Lowe L, Mo R, Lin K, de Sauvage FJ, Sasaki H, Hui CC, Dlugosz AA. 2002. Dissecting the oncogenic potential of Gli2: deletion of an NH(2)-terminal fragment alters skin tumor phenotype. Cancer Res. 62:5308-16.

    Smith PL, Myers JT, Rogers CE, Zhou L, Petryniak B, Becker DJ, Homeister JW, Lowe JB. Conditional control of selectin ligand expression and global fucosylation events in mice with a targeted mutation at the FX locus. J Cell Biol. 2002 Aug 19;158(4):801-15.

    Suh H. Gage PJ. Drouin J. Camper SA. Pitx2 is required at multiple stages of pituitary organogenesis: pituitary primordium formation and cell specification. Development - Supplement. 129(2):329-37, 2002.

    Wishart MJ, Dixon JE. 2002. The archetype STYX/dead-phosphatase complexes with a spermatid mRNA-binding protein and is essential for normal sperm production. Proc Natl Acad Sci U S A. Feb 19;99(4):2112-7.

    Yu T, Thomas DM, Zhu W, Goodman M, Gumucio DL. 2002. Regulation of fetal versus embryonic gamma globin genes: appropriate developmental stage expression patterns in the presence of HS2 of the locus control region. Blood. Feb 1;99(3):1082-4.

    Zavros Y, Rieder G, Ferguson A, Samuelson LC, Merchant JL. 2002. Hypergastrinemia in response to gastric inflammation suppresses somatostatin. Am J Physiol Gastrointest Liver Physiol. Jan;282(1):G175-83.

    Zavros Y, Rieder G, Ferguson A, Samuelson LC, Merchant JL. 2002. Genetic or chemical hypochlorhydria is associated with inflammation that modulates parietal and G-cell populations in mice. Gastroenterology. 2002 Jan;122(1):119-33.

    Zhang K, Kurachi S, Kurachi K.2 002. Genetic mechanisms of age regulation of protein C and blood coagulation.  J Biol Chem. Feb 8;277(6):4532-40.

    2001
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    Brinkmeier ML, Stahl JH, Gordon DF, Ross BD, Sarapura VD, Dowding JM, Kendall SK, Lloyd RV, Ridgway EC, Camper SA. 2001. Thyroid hormone-responsive pituitary hyperplasia independent of somatostatin receptor 2.Mol Endocrinol. 15:2129-2136.
     
    Brown NL, Patel S, Brzezinski J, Glaser T. 2001. Math5 is required for retinal ganglion cell and optic nerve formation.  Development. 128:2497-508.

    Cushman LJ, Watkins-Chow DE, Brinkmeier ML, Raetzman LT, Radak AL, Lloyd RV, Camper SA. 2001. Persistent Prop1 expression delays gonadotrope differentiation and enhances pituitary tumor susceptibility. Hum Mol Genet. May 15;10(11):1141-53.

    Domino SE, Zhang L, Gillespie PJ, Saunders TL, Lowe, JB. 2001. Deficiency of reproductive tract alpha(1,2)fucosylated glycans and normal fertility in mice with targeted deletions of the FUT1 or FUT2 alpha(1,2)fucosyltransferase locus. Molec. Cell. Biol. 21(24):8336-8345.

    Franic TV, Judd LM, Robinson D, Barrett SP, Scarff KL, Gleeson PA, Samuelson LC, Van Driel IR. 2001. Regulation of gastric epithelial cell development revealed in H(+)/K(+)-ATPase beta-subunit- and gastrin-deficient mice. Am J Physiol Gastrointest Liver Physiol. Dec;281(6):G1502-11.

    Homeister JW, Thall AD, Petryniak B, Maly P, Rogers CE, Smith PL, Kelly RJ, Gersten KM, Askari SW, Cheng G, Smithson G,  Marks RM, Misra AK, Hindsgaul O, von Andrian UH, Lowe JB.  2001. The alpha(1,3)fucosyltransferases FucT-IV and FucT-VII exert collaborative control over selectin-dependent leukocyte  recruitment and lymphocyte homing.  Immunity. Jul;15(1):115-26.

    Kearney JA. Plummer NW. Smith MR. Kapur J. Cummins TR. Waxman SG. Goldin AL. Meisler MH. 2001. A gain-of-function mutation in the sodium channel gene Scn2a results in seizures and behavioral abnormalities. Neuroscience. 102(2):307-17.

    Lee J, Prohaska JR, Thiele DJ. 2001. Essential role for mammalian copper transporter Ctr1 in copper homeostasis and embryonic development. Proc Natl Acad Sci U S A. 98:6842-7.

    Mears AJ, Kondo M, Swain PK, Takada Y, Bush RA, Saunders TL, Sieving PA, Swaroop A. 2001. Nrl is required for rod photoreceptor development. Nat Genet. 29:447-52.]

    Rao DS, Chang JC, Kumar PD, Mizukami I, Smithson GM, Bradley SV, Parlow AF, Ross TS.  Huntingtin Interacting Protein 1 Is a Clathrin Coat Binding Protein Required for Differentiation of late Spermatogenic  Progenitors.  Mol Cell Biol. 2001 Nov;21(22):7796-806.

    Scheuner D, Song B, McEwen E, Liu C, Laybutt R, Gillespie P, Saunders T, Bonner-Weir S, Kaufman RJ. Translational control is required for the unfolded protein response and in vivo glucose homeostasis. Mol Cell. 2001 Jun;7(6):1165-76.

    Seasholtz AF, Burrows HL, Karolyi IJ, Camper SA.2001. Mouse models of altered CRH-binding protein expression.  May;22(5):743-51.

    Smithson G, Rogers CE, Smith PL, Scheidegger EP, Petryniak B, Myers JT, Kim DS, Homeister JW, Lowe JB.  Fuc-TVII is required for T helper 1 and T cytotoxic 1 lymphocyte selectin ligand expression and recruitment in inflammation,  and together with Fuc-TIV regulates naive T cell trafficking to lymph nodes.  J Exp Med. 2001 Sep 3;194(5):601-14.

    Sun D, Samuelson LC, Yang T, Huang Y, Paliege A, Saunders T, Briggs J, Schnermann J. Mediation of tubuloglomerular feedback by adenosine: evidence from mice lacking adenosine 1 receptors. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9983-8.

    Weninger W, Ulfman LH, Cheng G, Souchkova N, Quackenbush EJ, Lowe JB, von Andrian UH.  Specialized contributions by alpha(1,3)-fucosyltransferase-IV and FucT-VII during leukocyte rolling in dermal microvessels.  Immunity. 2000 Jun;12(6):665-76.

    Zhao L. Bakke M. Krimkevich Y. Cushman LJ. Parlow AF. Camper SA. Parker KL. 2001. Steroidogenic factor 1 (SF1) is essential for pituitary gonadotrope function. Development. 128(2):147-54.

    Zhao L, Bakke M, Krimkevich Y, Cushman LJ, Parlow AF, Camper SA, Parker KL.  Hypomorphic phenotype in mice with pituitary-specific knockout of steroidogenic factor 1. Genesis. 2001 Jun;30(2):65-9.

    2000
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    Adams K. Ackerly H. Cunningham K. Dunnick W. 2000. A DNase I hypersensitive site near the murine gamma1 switch region contributes to insertion site independence of transgenes and modulates the amount of transcr