Research Publications that Used Animals Produced in the University of Michigan Transgenic Core
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Brackenbury WJ, Yuan Y, O'Malley HA, Parent JM, Isom LL. Abnormal neuronal patterning occurs during early postnatal brain development of Scn1b-null mice and precedes hyperexcitability. Proc Natl Acad Sci U S A. 2012 Dec 31. [Epub ahead of print]
Ding L, Morrison SJ. 2013. Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches. Ding L, Morrison SJ.Nature. 2013 Feb 24. doi: 10.1038/nature11885. [Epub ahead of print]
Tye KM, Mirzabekov JJ, Warden MR, Ferenczi EA, Tsai HC, Finkelstein J, Kim SY, Adhikari A, Thompson KR, Andalman AS, Gunaydin LA, Witten IB, Deisseroth K. 2012. Dopamine neurons modulate neural encoding and expression of depression-related behaviour. Nature. 2012 Dec 12. doi: 10.1038/nature11740. [Epub ahead of print].
Akhmetshina A, Palumbo K, Dees C, Bergmann C, Venalis P, Zerr P, Horn A, Kireva T, Beyer C, Zwerina J, Schneider H, Sadowski A, Riener MO, MacDougald OA, Distler O, Schett G, Distler JH. 2012. Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis. Nat Commun. 13;3:735.
Blumer JB, Oner SS, Lanier SM. 2012. Group II activators of G-protein signalling and proteins containing a G-protein regulatory motif. Acta Physiol (Oxf). 204:201-218.
Cho H, Kamenyeva O, Yung S, Gao JL, Hwang IY, Park C, Murphy PM, Neubig RR, Kehrl JH. 2012. The Loss of RGS Protein-Gαi2 Interactions Results in Markedly Impaired Mouse Neutrophil Trafficking to Inflammatory Sites. Mol Cell Biol. 2012 Sep 10. [Epub ahead of print]
Ding L, Saunders TL, Enikolopov G, Morrison SJ. 2012. Endothelial and perivascular cells maintain haematopoietic stem cells. Nature. 481:457-462.
Eberl M, Klingler S, Mangelberger D, Loipetzberger A, Damhofer H, Zoidl K, Schnidar H, Hache H, Bauer HC, Solca F, Hauser-Kronberger C, Ermilov AN, Verhaegen ME, Bichakjian CK, Dlugosz AA, Nietfeld W, Sibilia M, Lehrach H, Wierling C, Aberger F. 2012. Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells. EMBO Mol Med. 4:218-233.
Emmett LS, O'Shea KS. 2012. Geminin is required for epithelial to mesenchymal transition at gastrulation. Stem Cells Dev. 21:2395-2409.
Fang Q, Giordimaina AM, Dolan DF, Camper SA, Mustapha M. Genetic background of Prop1(df) mutants provides remarkable protection against hypothyroidism-induced hearing impairment. J Assoc Res Otolaryngol. 13:173-184.
Ferguson CJ, Lenk GM, Jones JM, Grant AE, Winters JJ, Dowling JJ, Giger RJ, Meisler MH. 2012. Neuronal expression of Fig4 is both necessary and sufficient to prevent spongiform neurodegeneration. Hum Mol Genet. 21:3525-3534.
Fukuda A, Wickman LT, Venkatareddy MP, Sato Y, Chowdhury MA, Wang SQ, Shedden KA, Dysko RC, Wiggins JE, Wiggins RC. Kidney Int. 2012. Angiotensin II-dependent persistent podocyte loss from destabilized glomeruli causes progression of end stage kidney disease. 81:40-55.
Gopalakrishnan K, Kumarasamy S, Abdul-Majeed S, Kalinoski AL, Morgan EE, Gohara AF, Nauli SM, Filipiak WE, Saunders TL, Joe B. 2012. Targeted disruption of Adamts16 gene in a rat genetic model of hypertension. Proc Natl Acad Sci U S A. 109:20555-20559.
Hurd EA, Micucci JA, Reamer EN, Martin DM. 2012. Delayed fusion and altered gene expression contribute to semicircular canal defects in Chd7 deficient mice. Mech Dev. 129:308-323.
Hüttemann M, Klewer S, Lee I, Pecinova A, Pecina P, Liu J, Lee M, Doan JW, Larson D, Slack E, Maghsoodi B, Erickson RP, Grossman LI.. 2012. Mice deleted for heart-type cytochrome c oxidase subunit 7a1 develop dilated cardiomyopathy. Mitochondrion.12:294-304.
Kaur K, Parra S, Chen R, Charbeneau RA, Wade SM, Jay PY, Neubig RR. 2012. Gαi2 signaling: friend or foe in cardiac injury and heart failure? Naunyn Schmiedebergs Arch Pharmacol. 385:443-453.
Krebs CJ, Schultz DC, Robins DM. 2012. The KRAB zinc finger protein RSL1 regulates sex- and tissue-specific promoter methylation and dynamic hormone-responsive chromatin configuration. Mol Cell Biol. 32:3732-3742.
Kwon M, Pavlov TS, Nozu K, Rasmussen SA, Ilatovskaya DV, Lerch-Gaggl A, North LM, Kim H, Qian F, Sweeney WE Jr, Avner ED, Blumer JB, Staruschenko A, Park F. 2012. G-protein signaling modulator 1 deficiency accelerates cystic disease in an orthologous mouse model of autosomal dominant polycystic kidney disease. Proc Natl Acad Sci U S A. 109:21462-21467.
Lapinski PE, Kwon S, Lubeck BA, Wilkinson JE, Srinivasan RS, Sevick-Muraca E, King PD. 2012. RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice. J Clin Invest. 122:733-747.
Li P, Neubig RR, Zingarelli B, Borg K, Halushka PV, Cook JA, Fan H. 2012. Toll-like Receptor-Induced Inflammatory Cytokines are Suppressed by Gain of Function or Overexpression of Gα (i2) Protein. Inflammation. 35:1611-1617.
Liu Z, Demitrack ES, Keeley TM, Eaton KA, El-Zaatari M, Merchant JL, Samuelson LC. 2012. IFNγ contributes to the development of gastric epithelial cell metaplasia in Huntingtin interacting protein 1 related (Hip1r)-deficient mice. Lab Invest. 92:1045-1057.
Miller SJ, Heist KA, Feng Y, Galbán CJ, Rehemtulla A, Ross BD, Fearon ER, Wang TD. 2012. Multimodal imaging of growth and rapamycin-induced regression of colonic adenomas in apc mutation-dependent mouse. Transl Oncol. 5:313-320.
Marionneau C, Carrasquillo Y, Norris AJ, Townsend RR, Isom LL, Link AJ, Nerbonne JM. 2012. The sodium channel accessory subunit Navβ1 regulates neuronal excitability through modulation of repolarizing voltage-gated K+ channels. J Neurosci. 32:5716-5727.
Prasov L, Nagy M, Rudolph DD, Glaser T. 2012. Math5 (Atoh7) gene dosage limits retinal ganglion cell genesis. Neuroreport. 23:631-634.
Rother E, Belgardt BF, Tsaousidou E, Hampel B, Waisman A, Myers MG Jr, Brüning JC. 2012. Acute selective ablation of rat insulin promoter-expressing (RIPHER) neurons defines their orexigenic nature. Proc Natl Acad Sci U S A. 109):18132-18137.
Schumacher MA, Donnelly JM, Engevik AC, Xiao C, Yang L, Kenny S, Varro A, Hollande F, Samuelson LC, Zavros Y. 2012. Gastric Sonic Hedgehog acts as a macrophage chemoattractant during the immune response to Helicobacter pylori. Gastroenterology. 142:1150-1159.
Skidmore JM, Waite MR, Alvarez-Bolado G, Puelles L, Martin DM. 2012. A novel TaulacZ allele reveals a requirement for Pitx2 in formation of the mammillothalamic tract. Genesis. 50:67-73.
Soofi A, Levitan I, Dressler GR. 2012. Two novel EGFP insertion alleles reveal unique aspects of Pax2 function in embryonic and adult kidneys. Dev Biol. 36: 241-250.
Spehalski E, Kovalchuk AL, Collins JT, Liang G, Dubois W, Morse HC 3rd, Ferguson DO, Casellas R, Dunnick WA. 2012. Oncogenic Myc translocations are independent of chromosomal location and orientation of the immunoglobulin heavy chain locus. Proc Natl Acad Sci U S A. 109:13716-13721.
Sun H, Xu Y, Sitkiewicz I, Ma Y, Wang X, Yestrepsky BD, Huang Y, Lapadatescu MC, Larsen MJ, Larsen SD, Musser JM, Ginsburg D. 2012. Inhibitor of streptokinase gene expression improves survival after group A streptococcus infection in mice. Proc Natl Acad Sci U S A 109:3469-3474.
Tao J, Zhu M, Wang H, Afelik S, Vasievich MP, Chen XW, Zhu G, Jensen J, Ginsburg D, Zhang B. 2012. SEC23B is required for the maintenance of murine professional secretory tissues. Proc Natl Acad Sci U S A. 109:E2001-2009.
Veniaminova NA, Hayes MM, Varney JM, Merchant JL. 2012. Conditional deletion of menin results in antral G cell hyperplasia and hypergastrinemia. Am J Physiol Gastrointest Liver Physiol. 303:G752-G764.
Wei Q, Fentress HM, Hoversten MT, Zhang L, Hebda-Bauer EK, Watson SJ, Seasholtz AF, Akil H. 2012. Early-Life Forebrain Glucocorticoid Receptor Overexpression Increases Anxiety Behavior and Cocaine Sensitization. Biol Psychiatry. 71:224-31.
Wu J, Liu C, Chen J, Yu X. 2012. RAP80 protein is important for genomic stability and is required for stabilizing BRCA1-A complex at DNA damage sites in vivo. J Biol Chem. 287:22919-22926.
Xiao H, Yu Z, Wu Y, Nan J, Merry DE, Sekiguchi JM, Ferguson DO, Lieberman AP, Dressler GR. 2012. A polyglutamine expansion disease protein sequesters PTIP to attenuate DNA repair and increase genomic instability. Hum Mol Genet. 21:4225-4236.
Xu Y, O'Brien WG 3rd, Lee CC, Myers MG Jr, Tong Q. 2012. Role of GABA release from leptin receptor-expressing neurons in body weight regulation. Endocrinology. 153:2223-2233.
Yu S, Zhou X, Hsiao JJ, Yu D, Saunders TL, Xue HH. 2012. Fidelity of a
BAC-EGFP transgene in reporting dynamic expression of IL-7Rα in T cells. Transgenic Res.21:201-15.
Castinetti F, Brinkmeier ML, Gordon DF, Vella KR, Kerr JM, Mortensen AH, Hollenberg A, Brue T, Ridgway EC, Camper SA. 2011. PITX2 AND PITX1 Regulate Thyrotroph Function and Response to Hypothyroidism. Mol Endocrinol.25:1950-1960.
Cho KW, Zhou Y,
Sheng L, Rui L. 2011. Lipocalin-13 Regulates Glucose Metabolism by Both
Insulin-dependent and Insulin-independent Mechanisms. Mol Cell Biol.
31:450-457.
Choi BY, Kim HM, Ito T, Lee KY, Li X, Monahan K, Wen Y, Wilson E, Kurima K, Saunders TL, Petralia RS, Wangemann P, Friedman TB, Griffith AJ. 2011. Mouse model of enlarged vestibular aqueducts defines temporal requirement of Slc26a4 expression for hearing acquisition. J Clin Invest. 121:4516-4525.
Clement LC, Avila-Casado C, Macé C, Soria E, Bakker WW, Kersten S, Chugh SS. 2011. Podocyte-secreted angiopoietin-like-4 mediates proteinuria in glucocorticoid-sensitive nephrotic syndrome. Nat Med. 17:117-122.
Dunnick WA, Shi
J, Holden V, Fontaine C, Collins JT. 2011. The role of
germline promoters and I exons in cytokine-induced gene-specific class
switch recombination. J Immunol.
186:350-358.
Dunnick WA, Shi J, Zerbato JM, Fontaine CA, Collins JT. 2011. Enhancement of antibody class-switch recombination by the cumulative activity of four separate elements. J Immunol. 187:4733-4743.
Corpening JC,
Deal KK, Cantrell VA, Skelton SB, Buehler DP, Southard-Smith EM. 2011.
Isolation and live imaging of enteric progenitors based on
Sox10-histone2bvenus transgene expression. Genesis. 49: 599-618.
Ghiasvand NM,
Rudolph DD, Mashayekhi M, Brzezinski JA 4th, Goldman D, Glaser T. 2011.
Deletion of a remote enhancer near ATOH7 disrupts retinal neurogenesis,
causing NCRNA disease. Nat Neurosci. 14:578-586
Grachtchouk M, Pero J, Yang SH, Ermilov AN, Michael LE, Wang A, Wilbert
D, Patel RM, Ferris J, Diener J, Allen M, Lim S, Syu LJ, Verhaegen M,
Dlugosz AA. 2011. Basal cell carcinomas in mice arise from hair
follicle stem cells and multiple epithelial progenitor populations. J
Clin Invest. 121:1768-81.
Hodish I, Absood A, Liu L, Liu M, Haataja L, Larkin D, Al-Khafaji A, Zaki A, Arvan P. 2011. In vivo misfolding of proinsulin below the threshold of frank diabetes. Diabetes.60:2092-2101.
Johnstone DB,
Zhang J, George B, Léon C, Gachet C, Wong H, Parekh R,
Holzman LB. 2011. Podocyte-specific deletion of Myh9 encoding
non-muscle myosin heavy chain 2A predisposes mice to glomerulopathy.
Mol Cell Biol. 31:2162-2170.
Jorge BS, Campbell CM,
Miller AR, Rutter ED, Gurnett CA,Vanoye CG, George AL, Jr, Kearney JA.
2011. Voltage-gated potassium channel KCNV2 (Kv8.2) contributes to
epilepsy susceptibility. Proc Natl Acad Sci
U S A. 108:5443-5448.
Kaur K, Kehrl JM, Charbeneau RA, Neubig RR. 2011. RGS-Insensitive Gα Subunits: Probes of Gα Subtype-Selective Signaling and Physiological Functions of RGS Proteins. Methods Mol Biol.756:75-98.
Kawashima Y, Géléoc GS, Kurima K, Labay V, Lelli A, Asai Y, Makishima T, Wu DK, Della Santina CC, Holt JR, Griffith AJ. 201. Mechanotransduction in mouse inner ear hair cells requires transmembrane channel-like genes. J Clin Invest. 121:4796-4809.
Kurima K, Hertzano R, Gavrilova O, Monahan K, Shpargel KB, Nadaraja G, Kawashima Y, Lee KY, Ito T, Higashi Y, Eisenman DJ, Strome SE, Griffith AJ. 2011. A Noncoding Point Mutation of Zeb1 Causes Multiple Developmental Malformations and Obesity in Twirler Mice. PLoS Genetics. 7(9):e1002307.
Lapinski PE, Qiao Y, Chang CH, King PD. 2011. A role for p120 RasGAP in thymocyte positive selection and survival of naive T cells. J Immunol. 187:151-163.
Layman WS, Hurd
EA, Martin DM. 2011. Reproductive
dysfunction and decreased GnRH neurogenesis in a mouse model of CHARGE
syndrome. Hum
Mol Genet. 20:3138-1350
Leinninger GM, Opland DM, Jo YH, Faouzi M, Christensen L, Cappellucci LA, Rhodes CJ, Gnegy ME, Becker JB, Pothos EN, Seasholtz AF, Thompson RC, Myers MG Jr. 2011. Leptin Action via Neurotensin Neurons Controls Orexin, the Mesolimbic Dopamine System and Energy Balance. Cell Metab. 14:313-323.
Li X, Li L, Pandey R, Byun JS, Gardner K, Qin Z, Dou Y. 2012. The Histone Acetyltransferase MOF Is a Key Regulator of the Embryonic Stem Cell Core Transcriptional Network.Cell Stem Cell. 11:163-178.
Lopez-Santiago
LF, Brackenbury WJ, Chen C, Isom LL. 2011. Na+ channel SCN1B
regulates dorsal root ganglion nociceptor excitability in vivo. J Biol Chem. 286:22913-22923.
Ma T, Keller JA,
Yu X. 2011. RNF8-dependent
histone ubiquitination during DNA damage response and spermatogenesis. Acta Biochim
Biophys Sin (Shanghai). 43:339-345.
McCormick JA, Nelson JH, Yang CL, Curry JN, Ellison DH. 2011. Overexpression of the sodium chloride cotransporter is not sufficient to cause familial hyperkalemic hypertension. .Hypertension. 58:888-894.
Mendez MP, Monroy
YK, Du M, Preston AM, Tolle L, Lin Y, VanDussen KL, Samuelson LC,
Standiford TJ, Curtis JL, Beck JM, Christensen PJ, Paine R 3rd. 2011. Overexpression of
sICAM-1 in the alveolar epithelial space results in an exaggerated
inflammatory response and early death in Gram negative pneumonia.
Respir Res. 12:12.
Miller SJ, Joshi BP, Feng Y, Gaustad A, Fearon ER, Wang TD. 2011. In vivo
fluorescence-based endoscopic detection of colon dysplasia in the mouse
using a novel Peptide probe. PLoS One. 6:e17384.
Patino GA, Brackenbury WJ, Bao Y, Lopez-Santiago LF, O'Malley HA, Chen C, Calhoun JD, Lafrenière RG, Cossette P, Rouleau GA, Isom LL. 2011. Voltage-gated Na+ channel β1B: a secreted cell adhesion molecule involved in human epilepsy. J Neurosci. 31:14577-14591.
Qiao XT, Gumucio DL. 2011. Current molecular markers for gastric progenitor cells and gastric cancer stem cells. J Gastroenterol. 46:855-865.
Regner KR, Nozu K, Lanier SM, Blumer JB, Avner ED, Sweeney WE Jr, Park F. 2011. Loss of activator of G-protein signaling 3 impairs renal tubular regeneration following acute kidney injury in rodents. FASEB J. 25:1844-55.
Rowe RG, Keena D, Sabeh F, Willis AL, Weiss SJ. 2011. Pulmonary fibroblasts mobilize the membrane-tethered matrix metalloprotease, MT1-MMP, to destructively remodel and invade interstitial type I collagen barriers. Am J Physiol Lung Cell Mol Physiol. 301:L683-L692.
Rowe RG, Lin Y, Shimizu-Hirota R, Hanada S, Neilson EG, Greenson JK, Weiss SJ. 2011. Hepatocyte-derived Snail1 propagates liver fibrosis progression. Mol Cell Biol. 31:2392-2403.
Saqui-Salces M, Keeley TM, Grosse AS, Qiao XT, El-Zaatari M, Gumucio DL, Samuelson LC, Merchant JL. 2011. Gastric tuft cells express DCLK1 and are expanded in hyperplasia. Histochem Cell Biol. 136:191-204.
Schwab KR, Patel SR,
Dressler GR. 2011. Role of PTIP in class
switch recombination and long-range chromatin interactions at the
immunoglobulin heavy chain locus. Mol Cell Biol.
31:1503-1511.
Sheng L, Cho KW, Zhou Y, Shen H, Rui L. 2011. Lipocalin 13 protein protects against hepatic steatosis by both inhibiting lipogenesis and stimulating fatty acid β-oxidation. J Biol Chem. 286:38128-38135.
Singer BH, Gamelli AE, Fuller CL, Temme SJ, Parent JM, Murphy GG. 2011. Compensatory network changes in the dentate gyrus restore long-term potentiation following ablation of neurogenesis in young-adult mice. Proc Natl Acad Sci U S A. 108:5437-5442.
Stein AB, Jones TA, Herron TJ, Patel SR, Day SM, Noujaim SF, Milstein ML, Klos M, Furspan PB, Jalife J, Dressler GR. 2011.Loss of H3K4 methylation destabilizes gene expression patterns and physiological functions in adult murine cardiomyocytes. J Clin Invest. 2641-2650.
Strickland FM, Hewagama A, Lu Q, Wu A, Hinderer R, Webb R, Johnson K, Sawalha AH, Delaney C, Yung R, Richardson BC. 2011. Environmental exposure, estrogen and two X chromosomes are required for disease development in an epigenetic model of lupus. J Autoimmun. J Autoimmun. 38):J135-143.
Tan M, Zhao Y, Kim S-J, Liu M, Jia L, Saunders TL, Zhu U, Sun Y. 2011. SAG/RBX2/ROC2 E3 Ubiquitin Ligase Is Essential for Vascular and Neural Development by Targeting NF1 for Degradation. Dev Cell. 21:1062-1076.
Terahara K, Nochi T, Yoshida M, Takahashi Y, Goto Y, Hatai H, Kurokawa
S, Jang MH, Kweon MN, Domino SE, Hiroi T, Yuki Y, Tsunetsugu-Yokota Y,
Kobayashi K, Kiyono H. 2011. Distinct
fucosylation of M cells and epithelial cells by Fut1 and Fut2,
respectively, in response to intestinal environmental stress. Biochem
Biophys Res Commun. 404:822-828.
Waterson RE,
Thompson CG, Mabe NW, Kaur K, Talbot JN, Neubig RR, Rorabaugh BR. 2011.
G{alpha}i2-mediated protection from ischaemic injury is modulated by
endogenous RGS proteins in the mouse heart. Cardiovasc Res. 91: 45-52.
Wei J, Melichian D, Komura K, Hinchcliff M, Lam AP, Lafyatis R, Gottardi CJ, MacDougald OA, Varga J. 2011. Canonical Wnt signaling induces skin fibrosis and subcutaneous lipoatrophy: a novel mouse model for scleroderma? Arthritis Rheum. 63:1707-1717.
Witten IB, Steinberg EE, Lee SY, Davidson TJ, Zalocusky KA, Brodsky M, Yizhar O, Cho SL, Gong S, Ramakrishnan C, Stuber GD, Tye KM, Janak PH, Deisseroth K. 2011. Recombinase-driver rat lines: tools, techniques, and optogenetic application to dopamine-mediated reinforcement. Neuron. 72:721-733.
Wu J, Chen Y, Lu LY, Wu Y, Paulsen MT, Ljungman M, Ferguson DO, Yu X. 2011. Chfr and RNF8 synergistically regulate ATM activation. Nat Struct Mol Biol. 18:761-768.
Yasuda M, Johnson-Venkatesh EM, Zhang H, Parent JM, Sutton MA, Umemori H. 2011. Multiple forms of activity-dependent competition refine hippocampal circuits in vivo. Neuron. 70:1128-1142.
Yu T, Shakkottai VG, Chung C, Lieberman AP. 2011. Temporal and cell-specific deletion establishes that neuronal Npc1 deficiency is sufficient to mediate neurodegeneration.. Hum Mol Genet. 20: 4440-4451.
Zacharias AL,
Lewandoski M, Rudnicki MA, Gage PJ. 2011. Pitx2 is an upstream
activator of extraocular myogenesis and survival. Dev Biol.
349:395-405.
Zacharias WJ, Madison BB, Kretovich KE, Walton KD, Richards N, Udager AM, Li X, Gumucio DL. 2011. Hedgehog signaling controls homeostasis of adult intestinal smooth muscle. Dev Biol. 355:152-162.
Zhang K, Wang S,
Malhotra J, Hassler JR, Back SH, Wang G, Chang L, Xu W, Miao H,
Leonardi R, Chen YE, Jackowski S, Kaufman RJ. 2011. The unfolded protein
response transducer IRE1α prevents ER stress-induced hepatic steatosis. EMBO J.
30:1357-1375.
Anand S, Majeti
BK, Acevedo LM, Murphy EA, Mukthavaram R, Scheppke L, Huang M, Shields
DJ, Lindquist JN, Lapinski PE, King PD, Weis SM, Cheresh DA. 2010.
MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to
facilitate pathological angiogenesis. Nat Med. 16:909-14.
Bjork BC,
Fujiwara Y, Davis SW, Qiu H, Saunders TL, Sandy P, Orkin S, Camper SA,
Beier DR. 2010. A Transient Transgenic RNAi Strategy for Rapid
Characterization of Gene Function during Embryonic Development. PLoS
One. 5:e14375.
Brackenbury WJ,
Calhoun JD, Chen C, Miyazaki H, Nukina N, Oyama F, Ranscht B, Isom LL. 2010. Functional
reciprocity between Na+ channel Nav1.6 and beta1 subunits in the
coordinated regulation of excitability and neurite outgrowth. Proc Natl Acad Sci
U S A. 107:2283-2288.
Carvalho LR,
Brinkmeier ML, Castinetti F, Ellsworth BS, Camper SA. 2010.
Corepressors TLE1 and TLE3 interact with HESX1 and PROP1. Mol
Endocrinol. 24:754-65.
Chun YH, Lu Y, Hu Y, Krebsbach PH, Yamada Y, Hu JC, Simmer JP. 2010.
Transgenic rescue of enamel phenotype in Ambn null mice. J Dent Res.
89:1414-1420.
Daniel
JA, Santos MA, Wang Z, Zang C, Schwab KR, Jankovic M, Filsuf D, Chen
HT, Gazumyan A, Yamane A, Cho YW, Sun HW, Ge K, Peng W, Nussenzweig MC,
Casellas R, Dressler GR, Zhao K, Nussenzweig A. 2010. PTIP
promotes chromatin changes critical for immunoglobulin class switch
recombination. Science. 329:917-923.
Davis
SW,
Castinetti F, Carvalho LR, Ellsworth BS, Potok MA, Lyons RH, Brinkmeier
ML, Raetzman LT, Carninci P, Mortense AH, Hayashizaki Y, Arnhold IJ,
Mendonça BB, Brue T, Camper SA. 2010. Molecular
mechanisms of pituitary organogenesis: In search of novel regulatory
genes. Mol
Cell
Endocrinol. 323:4-19.
Depianto D, Kerns ML, Dlugosz AA, Coulombe PA. 2010. Keratin 17
promotes epithelial proliferation and tumor growth by polarizing the
immune response in skin. Nat Genet. 42:910-914.
Elrick MJ,
Pacheco CD, Yu T, Dadgar N, Shakkottai VG, Ware C, Paulson HL,
Lieberman AP. 2010. Conditional
Niemann-Pick C mice demonstrate cell autonomous Purkinje cell
neurodegeneration. Hum Mol
Genet.19:837-847.
El-Zaatari M,
Zavros Y, Tessier A, Waghray M, Lentz S, Gumucio D, Todisco A, Merchant
JL. 2010. Intracellular calcium-release and protein kinase C-activation
stimulate sonic hedgehog gene expression during gastric acid secretion.
Gastroenterology. 139:2061-2071.
Hebda-Bauer EK,
Pletsch A, Darwish H, Fentress H, Simmons TA, Wei Q, Watson SJ, Akil H.
Forebrain glucocorticoid receptor overexpression increases
environmental reactivity and produces a stress-induced spatial
discrimination deficit. Neuroscience. 169:645-653.
Hodish I, Liu M,
Rajpal G, Larkin D, Holz RW, Adams A, Liu L, Arvan P. 2010. Misfolded
proinsulin affects bystander proinsulin in neonatal diabetes. J Biol
Chem. 285:685-94.
Hurd EA, Poucher
HK, Cheng K, Raphael Y, Martin DM. 2010. The ATP-dependent chromatin
remodeling enzyme CHD7 regulates pro-neural gene expression and
neurogenesis in the inner ear. Development. 137:3139-3150.
Jappar D, Wu SP,
Hu Y, Smith DE. 2010 Significance and regional dependency of peptide
transporter (PEPT) 1 in the intestinal permeability of glycylsarcosine:
in situ single-pass perfusion studies in wild-type and Pept1 knockout
mice. Drug Metab Dispos. 38:1740-6.
Kaufman
RJ,
Back SH, Song B, Han J, Hassler J. 2010. The unfolded
protein response is required to maintain the integrity of the
endoplasmic reticulum, prevent oxidative stress and preserve
differentiation in β-cells. Diabetes Obes Metab. 12 Suppl 2:99-107.
Kitajiri
SI, Sakamoto T, Belyantseva IA, Goodyear RJ, Stepanyan R, Fujiwara I,
Bird JE, Riazuddin S, Riazuddin S, Ahmed ZM, Hinshaw JE, Sellers J,
Bartles JR, Hammer JA 3rd, Richardson GP, Griffith AJ, Frolenkov GI,
Friedman TB. 2010. Actin-Bundling
Protein TRIOBP Forms Resilient Rootlets of Hair Cell Stereocilia
Essential for Hearing. Cell.
141:786 - 798.
Krebs CJ, Robins
DM. 2010. A pair of mouse KRAB zinc finger proteins modulates multiple
indicators of female reproduction. Biol Reprod. 82:662-668.
Lefevre GM, Patel
SR, Kim D, Tessarollo L, Dressler GR. 2010. Altering a histone H3K4
methylation pathway in glomerular podocytes promotes a chronic disease
phenotype. PLoS Genet. 6:e1001142.
Leshan RL, Opland
DM, Louis GW, Leinninger GM, Patterson CM, Rhodes CJ, Münzberg H, Myers
MG Jr. 2010. Ventral tegmental area leptin receptor neurons
specifically project to and regulate cocaine- and amphetamine-regulated
transcript neurons of the extended central amygdala. J Neurosci.
30:5713-23.
Li JY, Chai BX, Zhang W, Wang H, Mulholland MW. 2010.Expression of ankyrin repeat and suppressor of cytokine signaling box protein 4 (Asb-4) in proopiomelanocortin neurons of the arcuate nucleus of mice produces a hyperphagic, lean phenotype.Endocrinology.151:134-142.
Li X, Corsa CA, Pan PW, Wu L, Ferguson D, Yu X, Min J, Dou Y. 2010. MOF and H4 K16 acetylation play important roles in DNA damage repair by modulating recruitment of DNA damage repair protein Mdc1. Mol Cell Biol. 30:5335-5347.
Lo CM, King A,
Samuelson LC, Kindel TL, Rider T, Jandacek RJ, Raybould HE, Woods SC,
Tso P. 2010. Cholecystokinin
knockout mice are resistant to high-fat diet-induced obesity. Gastroenterology.
138:1997-2005.
Louis GW,
Leinninger GM, Rhodes CJ, Myers MG Jr. 2010. Direct innervation and
modulation of orexin neurons by lateral hypothalamic LepRb neurons. J
Neurosci. 30:11278-11287.
Lu LY, Wu J, Ye
L, Gavrilina G, Saunders TL, Yu X. 2010. RNF8-Dependent
Histone
Modifications Regulate Nucleosome Removal during Spermatogenesis, Dev. Cell. 18:371-384.
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