Jump to contentUniversity of Michigan Health System - link
Department of Internal Medicine - link

SCLERODERMA PROGRAM
Division of Rheumatology

search this site
 

About Us



Faculty

UMHS Affiliates
Pulmonary Hypertension Program
Scleroderma Lung Clinic



Research




Friends & Supporters




FOR PATENTS
Learn About Scleroderma



For Health Care Professionals




Related Links




Internal Resources




Internal Medicine Divisions




Scleroderma Home


 
Pulmonary Hypertension Program

Pulmonary hypertension (high blood pressure in the lungs) is the leading cause of death and disability in patients with scleroderma. This is, however, the area in which advances in diagnosis and treatment are making rapid progress.

The only drugs approved by the Food & Drug Administration for use in scleroderma are agents recently approved for pulmonary hypertension. These include Flolan® (an intravenous prostacyclin), Treprostinil® (a prostacyclin that is given either subcutaneously or intravenously), Ventavis® (an inhaled prostacyclin), Tracleer ® (a pill taken by mouth) and Revatio® (a pill containing the active ingredient in Viagra).

Other similar drugs are at late stages of preapproval clinical trials and there is great interest in studying the benefits of various combination therapies.

The University of Michigan is home to a world class Pulmonary Hypertension Program. Based in the Division of Cardiology, the Program is directed by Vallerie V. McLaughlin, M.D. – a recognized thought leader in pulmonary hypertension and features the participation of many other expert faculty, including Melvyn P. Rubenfire, M.D. The Program is supported by a staff of nurse experts who are skilled and experienced in managing these complex treatments.

Patients in the Scleroderma Program are routinely assessed for the possible presence of pulmonary hypertension and referred to the Pulmonary Hypertension Program for consultation and continuing care. The Pulmonary Hypertension Program accepts direct referrals as well.

Pulmonary hypertension is considered if there is shortness of breath or fatigue during physical activity. Careful physical examination can provide clues as can non-invasive laboratory testing, including pulmonary function testing, Doppler echocardiograms and simple exercise tests. Correct medical diagnosis and care usually requires a right heart catheterization.

The University of Michigan Pulmonary Hypertension Program has an active interest in developing new treatments. Many of their trials permit participation by patients with scleroderma. For more information please see Research – Clinical Trials.

 

Back to Faculty - Top of Page

 
   
   

U-M Medical School
| Hospitals & Health Centers | U-M | TEXT-ONLY

University of Michigan Health System
1500 E. Medical Center Drive  Ann Arbor, MI 48109   734-936-4000
(c) copyright Regents of the University of Michigan
Template developed & maintained by: Public Relations & Marketing Communications
Contact UMHS

 
The University of Michigan Health System web site does not provide specific medical advice and does not endorse any medical or professional service obtained through information provided on this site or any links to this site.
Complete disclaimer and Privacy Statement

UMHS HOME

Health Topics A-Z

For Patients & Families

For Health Professionals

Search Tools & Index