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 James R. Seibold, M.D., is the Marvin and Betty Danto Research Professor of Connective Tissue Research and Professor of Internal Medicine in the Division of Rheumatology. He is also the Director of the University of Michigan Scleroderma Program.
He joined the faculty in August of 2004 after 24 years at the University of Medicine and Dentistry of New Jersey–Robert Wood Johnson Medical School in New Brunswick, NJ. He served as Chief of the Division of Rheumatology; Director of the Clinical Research Center; and Chair of the Department of Clinical Pharmacology during which he occupied the William H. Conzen Chair of Clinical Pharmacology.
The author of more than 350 scientific publications, Dr. Seibold has served on the editorial boards of both Arthritis & Rheumatism and the Annals of Rheumatic Diseases, and as editor of the scleroderma section of the Yearbook of Rheumatology, Arthritis and Musculoskeletal Disease and Editor-in-Chief of Scleroderma Care and Research. He is currently Managing Editor of Scleroderma Care and Research and on the Editorial Board of Clinical and Experimental Rheumatology.
His major research interests include systemic sclerosis, Raynaud’s phenomenon, clinical trial design, and drug development in rheumatology. Dr. Seibold has been cited in The Best Doctors in America continuously since the first edition in 1994 and has won numerous awards, including the Arthritis Foundation’s Physician of the Year . He is the founder and current President of the Scleroderma Clinical Trials Consortium and active in several patient organizations, including the Pulmonary Hypertension Association, the Scleroderma Research Foundation, and serves as Chair of the Medical Advisory Board of the International Scleroderma Network.
Dr. Seibold received his undergraduate degree in biochemistry from Louisiana State University in Baton Rouge, LA, and his medical degree from SUNY at Stony Brook School of Medicine in Stony Brook, NY. He completed postdoctoral training as an intern and resident in internal medicine at Long Island Jewish-Hillside Medical Center in New Hyde Park, NY, and a fellowship at the Division of Rheumatology and Clinical Immunology at the University of Pittsburgh School of Medicine in Pittsburgh, PA. He is a Fellow of the American College of Rheumatology and the American College of Physicians.
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 Kristine Phillips, M.D., Ph.D., is Clinical Assistant Professor in the Division of Rheumatology and the Scleroderma Program. She joined the University of Michigan faculty in 2005. Dr. Phillips’ role in the Scleroderma Program includes patient care and clinical research.
Dr. Phillips received her undergraduate and doctorate degrees from Louisiana State University and her medical degree from Johns Hopkins University School of Medicine. She completed postdoctoral training as an intern and resident in internal medicine at Johns Hopkins Hospital and a rheumatology fellowship at Brigham and Women’s Hospital in Boston, MA. Prior to joining the University of Michigan faculty, she was Instructor in Medicine at Harvard Medical School and Associate Physician at Brigham and Women’s Hospital. She is a Fellow of the American College of Rheumatology and is board certified in both internal medicine and rheumatology.
Dr. Phillips’ research during her Rheumatology fellowship at Brigham and Women’s Hospital focused on the role of post-transcriptional control mechanisms of the expression of pro-inflammatory proteins and susceptibility to inflammatory arthritis. Her Ph.D. work focused on leukocyte adhesion and microvascular inflammation.
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 Elena Tishkowski, M.D., is clinical lecturer in the Division of Rheumatology and active faculty in the University of Michigan Scleroderma Program. She joined the faculty in August of 2005 after she finished rheumatology fellowship training at Detroit Medical Center/Wayne State University. She is board certified in both internal medicine and rheumatology.
Her interest in scleroderma started during her general medicine internship at the University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School in New Brunswick, NJ., where she received clinical and research training in their Scleroderma Program, directed at that time by James R. Seibold, M.D.
Dr. Tishkowski is a member of the Board of Directors of the Scleroderma Foundation - Michigan Chapter and is a very involved presence in the education of patients.
Her roles in the University of Michigan Scleroderma Program include patient care and education of medical students and postgraduate trainees. She is active in numerous research projects focused currently on treatment strategies, measures of outcome and translational studies of potential laboratory markers of disease activity.
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 Ann J. Impens, PhD, MPH, was promoted to Research Investigator in the University of Michigan Scleroderma Program. Dr. Impens had previously worked in the Scleroderma Program as a Clinical Research Coordinator since 2005.
Dr. Impens’ educational background is unique for the field of scleroderma and she brings to her research new and interesting approaches to clinical investigation. After obtaining an undergraduate degree in Belgium, Dr. Impens subsequently moved to the United States where she received graduate degrees in two distinct fields: a Master’s degree in Guidance and Counseling and subsequently a Master’s degree and a Ph.D. degree in Health Behavior.
Dr. Impens has developed and leads a variety of projects concerned with quality of life and measures of outcome in populations with scleroderma. She has presented abstracts and defended posters at the American College of Rheumatology, EULAR and the American Psychological Association. She has served as lead investigator on a study validating the Michigan Hand Questionnaire in scleroderma and assessing the contributions to hand disability of diverse domains of scleroderma. She has also led a novel project on quality of female sexual function in scleroderma. She has been an important contributor to our studies of exercise capacity in scleroderma and is currently mentoring a postdoctoral fellow in a project investigating minimal clinically important differences in the six minute walk test. Dr. Impens is the lead investigator on a novel study of pain and pain perception in scleroderma and a related project on body image and self-esteem.
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 Yong Hou, M.D., joined the University of Michigan Scleroderma Program as a postdoctoral research fellow in November, 2006 and is the first member of a recurring collaborative exchange program with Peking Union Medical College in Beijing, China, where Dr. Hou received his medical. degree. Dr. Hou is currently participating in clinical and laboratory scleroderma research.
Dr. Hou is Associate Professor in the Department of Rheumatology at Peking Union Medical College in Beijing, where he has an active practice and has been involved in multiple clinical research projects.
Dr. Hou’s work at the University of Michigan will focus on molecular mechanisms of blood vessel damage and growth in scleroderma skin.
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 Suparaporn Wangkaew, M.D., recently joined the University of Michigan Scleroderma Program in October, 2007 as a postdoctoral research fellow. Dr. Wangkaew received her M.D. from Chiang Mai University in Thailand, where she is an Instructor in the Department of Internal Medicine at Chiang Mai University. Dr. Wangkaew will extend her training in clinical research in the field of scleroderma interstitial lung disease and pulmonary arterial hypertension.
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