Santiago Schnell, DPhil (Oxon), FRSC

Interim Chair of Department of Molecular & Integrative Physiology

John A. Jacquez Collegiate Professor of Physiology

Professor of Molecular & Integrative Physiology

Professor of Computational Medicine & Bioinformatics

William K. Brehm Investigator, Brehm Center for Diabetes Research


Contact Information

Brehm Center 5132

1000 Wall Street

Ann Arbor, MI 48105-1912


(734) 615-8733  office

(734) 232-8162  fax


Twitter: @SantiagoSchnell




Dr. Schnell received his License in Biology (degree equivalent to a MSc) from Universidad Simón Bolívar (Venezuela) and then a DPhil in Mathematical Biology from the University of Oxford (United Kingdom), respectively. After completing his DPhil, Dr. Schnell held two research positions at the University of Oxford: Junior Research Fellow at Christ Church (a college of Oxford) and Senior Research Fellow of the Wellcome Trust at the Centre for Mathematical Biology in the Mathematical Institute. In 2004, he moved to Indiana University, where he was Assistant Professor of Informatics at the Indiana University School of Informatics & Computing, and Associate Director of the Biocomplexity Institute until 2008.


In 2008, he joined the Department of Molecular & Integrative Physiology at the University of Michigan Medical School as Associate Professor.  He is also appointed Associate Professor of Computational Medicine & Bioinformatics, and William K. Brehm Investigator at the Brehm Center for Diabetes Research.  Dr. Schnell is faculty of the Michigan Diabetes Research and Training Center, Center for Organogenesis, Molecular & Cellular Biology Program, Michigan Center for Integrative Research in Critical Care, Michigan Institute for Computational Discovery and Engineering, and Michigan Institute for Data Science. In 2015, Dr. Schnell was promoted to the rank of Professor, and was appointed as the John A. Jacquez College Professor of Physiology in 2017. He has been serving as the interim chair of the Department of Molecular & Integrative Physiology since August, 2017.


Dr. Schnell is the Director of the In Sicilo Protein Analysis Module of the University of Michigan Protein Folding Disease Initiative.  He is co-Director of the University of Michigan Systems and Integrative Biology Training Grant, and Associate Director of the Multidisciplinary Training Program in Basic Diabetes Research. He also serves as  Program Director of the Educational Program Interfacing Computation and Engineering with Digestive and Metabolic Physiology, and the co-Director of the Summer Undergraduate Fellowship Program at the Department of Molecular & Integrative Physiology.  His research has been continuously funded by National Institutes of Health, National Science Foundation and other entities.


Dr. Schnell is a member of the Standards for Reporting Enzymology Data (STRENDA) Commission to establish standard forms of data presentations for enzyme research and improve the quality of data reporting in the scientific literature. He was elected Fellow of the Royal Society of Chemistry for his for work and discoveries in theoretical enzyme kinetics and modeling reactions inside cells in 2011, and Fellow of the American Association for the Advancement of Science for his contributions to the theoretical modeling of complex biochemical reactions and optional estimation of their rates in 2016.  He is also Fellow of the Society for Mathematical Biology, and Foreign Corresponding Fellow of the Latin American Academy of Sciences.


Awards and Honors



Memberships and Boards



The Schnell Lab, University of Michigan Medical School

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