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Dr. Eva Stem cells hold potential for medicine, economy, Feldman tells Detroit Economic Club

Dr. Eva Feldman and A. Alfred Taubman

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As Michigan struggles to find its way out of economic distress, stem cell research has the potential of leading the state into a more prosperous future, in addition to being one of the most important medical breakthroughs in a generation.

That was the message of Dr. Eva Feldman, director of the Program for Neurology Research & Discovery at the Medical School, as she addressed the Detroit Economic Club meeting on Tuesday.

Feldman also announced that the new Consortium for Stem Cell Therapies at U-M would be accepting embryo donations for the first time, according to careful guidelines spelled out by government and university regulations.

Also there for the announcement and to address media were Sue O'Shea, the Crosby-Kahn Collegiate Professor of Cell and Developmental Biology and professor of cell and developmental biology, and Gary Smith, associate professor of obstetrics and gynecology, and associate professor of molecular and integrative physiology and of urology. O’Shea and Smith are co-directors of the Consortium for Stem Cell Therapies.

In addition, Feldman told the overflow crowd that a bill currently before the Legislature that would place restrictions on stem cell research is a step backward for the state and for medical science.

In November 2008, voters in the state of Michigan approved a constitutional amendment lifting restrictions on embryonic stem cell research in the state. For the first time, medical scientists in Michigan could derive embryonic stem cell lines, an important tool in finding new treatments and cures for a wide range of diseases.

Feldman described the major strides that have been made in the past year in Michigan, as a result of the vote.

“Michigan went from being one of the five states which prohibited this kind of research,” said Feldman, “to being at the very forefront of stem cell science.

“This work has incredible potential for both curing disease and rejuvenating an ailing economy.”

Feldman explained how stem cells have the unique ability to reproduce themselves indefinitely and to develop into any tissue type in the human body. For this reason, they offer unprecedented applications in the fields of regenerative medicine, tissue engineering, drug testing and other technologies that scientists have not even dreamed of yet.

Stem cell research also offers unique opportunities for economic growth in the life science sector, which has demonstrated remarkable vitality while the rest of the Michigan economy has languished in recession.

Citing a recent study by Wayne State University, Feldman explained that stem cell research has the potential to create nearly 4,000 new jobs, add $80 million per year to the state’s payrolls, while saving Michigan $80 million per year in health care costs.

The university long has been a leader in medical research. The school received more money in recent stimulus grants from the NIH than any other university in the country — $99.7 million. Nearly $7 million was earmarked for stem cell research.

A. Alfred Taubman, founder and chair of the Taubman Institute, introduced Feldman. He, too, cited the promise of stem cell research in the economic realm.

“I’m convinced it is one of our best opportunities to attract investments, create jobs and emerge from this recession with a revitalized economy.”

Taubman and Feldman touched upon legislation that has been introduced in the Legislature that would once again restrict stem cell research.

Taubman said if the legislation succeeds, it would place huge roadblocks in the way of progress.
“Michigan will once again be seen as a state unfriendly to science. The jobs, the talent and the cures will go elsewhere.

“We can’t let that happen.”

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Big House Big Heart Takes a Run at ALS

Call it happy feet, if you will. The 3rd annual Big Heart Big House run brought 10,000 participants to the streets of Ann Arbor, doubling the amount of money it raised for local charities. This year’s event on October 4, 2009, racked up half a million dollars in aid for worthy organizations.

The Program for Neurology Research & Discovery is one of the prime beneficiaries, as are the Cardiovascular Center and the Mott Children’s Hospital. 

In addition, A. Alfred Taubman – Founder and Chair of U-M’s Alfred Taubman Medical Research Institute – received the Phil Bowen Award, given each year to the individual who does the most to raise public consciousness about ALS.

He joined U-M President Mary Sue Colemen in kicking off the race.

The Big House Big Heart run is the only charitable event that gets to use the U-M Stadium. Participants can choose to run a 10K or 5K course or join a 1 mile Fun Run. Everyone finishes by running through the tunnel that leads to the football field and onto the 50 yard line, where they can watch themselves on the Jumbotron.

“Seeing all those runners bursting into the Big House, their arms raised in victory, is a marvelous sight,” said Eva Feldman, Director of the Program for Neurology Research & Discovery.

“But it’s even more thrilling to know that all these people are running to find a cure for ALS and to support other worthwhile charities.” 

Beside the primary recipients, participants in the run can raise money for charities of their choosing.

To learn more about the event, visit www.bighousebigheart.com.



ALS Day at Comerica Park

Seventy years ago this summer, Lou Gehrig gave one of the most famous farewell speeches in American sports history. “I am the luckiest man on the face earth,” he told the fans at Yankee Stadium.

The Iron Horse, who had played in 2,130 consecutive games, was knocked out of the New York lineup by ALS – the same terrible disease that the Program for Neurology Research & Discovery struggles to understand every day in its laboratories.

Throughout the season, Major League Baseball is honoring the memory of Lou Gehrig and the fight against ALS at ballparks around the country.

On Sunday afternoon, August 9, the Detroit Tigers held a special ALS Day, to raise public awareness about the disease and to encourage people to participate in the Big House Big Heart Run/Walk on October 4. This annual Ann Arbor event raises money for ALS research at U-M and other worthwhile causes.

Dr. Eva Feldman, Director of the Program for Neurology Research & Discovery, told 42,000 Detroit Tigers fans about the ongoing battle to find a cure for ALS, the terrible disease that knocked Lou Gehrig out of the Yankee lineup 70 years ago.

A. Alfred Taubman, Chair of the Taubman Institute, joined event organizer Mike Highfield in urging the crowd to fight the disease by signing up for the Big House Big Heart Run on Sunday, October 4.

Ten thousand people are expected to take part in the event. They will make their way through the streets of Ann Arbor and into the tunnel leading onto the U-M Stadium football field, where they will watch themselves on the Jumbotron as the finish the race on the 50 yard line.

Taubman, along with U-M President Mary Sue Coleman, will kick off the race. He will also receive the Phil Bowen Award, given each year to the individual who does the most to raise public consciousness about ALS.



Women Talk Health with Women

Women’s Health & Fitness Day provides a heavy dose of good advice

Women often interact with doctors only when they’re sick. At least once a year, women students in the University of Michigan’s Medical School seek to change that by holding an annual Women’s Health & Fitness Day.

This year on January 24, more than 225 women jammed Ypsilanti High School to hear from a wide variety of health-care professionals about how they could lead healthier, happier, more productive lives.

Seventeen medical students and more than 20 community leaders volunteered their time to make this free event possible. It was funded, in part, by the Program for Neurology Research and Discovery.
The day began with a free breakfast and a round of yoga. Then, participants took part in 19 workshops on topics such as depression, sexuality, obesity, financial health and stress management. The sessions were taught by University of Michigan Health System doctors, nurses, physical therapists and nutritionists.
The program culminated with a rousing talk by Sheila Taorima, the Olympic champion from Michigan, who recently founded Friendsport, a nonprofit organization that seeks to inspire Americans to adopt healthier lifestyles.

“The day was a success with many great worksops and Sheila Taormina’s inspiring keynote,” said Cassandra Niemi, co-director of the event with Lane Frasier. “It was wonderful to talk with so manny women who were energized by new friends and by the knowledge they gained from health-care professionals.



 

Sponsor Steve Sarns from NuStep and Becca Schumaker, Michigan Regional Director of the Muscular Dystrophy Association, join Dr. Eva Feldman in the Big House at the end of the race.

Beyond the Laboratory

None of our progress would have been possible without the thousands of people who donate their time, money and hard work to support the Program for Neurology & Discovery.

A Run for the Research Money

On Sept. 28, the Big House Big Heart event drew 7,000 runners and walkers to the U-M stadium, where they got to watch themselves cross the 50-yard-line on the stadium’s Jumbotron. Nearly $250,000 was raised for charity. Two great U-M causes were the primary recipients: The Program for Neurology Research & Discovery and the C.S. Mott Children’s Hospital.

The man with the biggest heart is local attorney Mike Highfield, who started the run in 2007 after watching Phil Bowen, his friend and law partner, pass away from ALS. He and sponsor, Running Fit, have made this an instant fall tradition.

Next year’s date has already been chosen: October 4. For more information, visit the Big House Big Heart Web site.




A Community Fights Back

Gretchen Spreitzer and her husband Bob Schoeni thank all those who participated in this year's A2A3 Family Field Day.

When Dr. Bob Schoeni was diagnosed with ALS this summer, it was a shock to friends, colleagues and family in the Ann Arbor community. A popular U-M professor Bob has touched a lot of lives, especially through his coaching of girls sports. A large number of Ann Arbor girls call him simply, “Coach Bob.”

When his friends and coworkers heard about his condition, they organized a non-profit, A2A3 (Ann Arbor Active Against ALS), to support ALS research. Some of their initiatives include Training for a Cure, Coaching for a Cure, and Kids Active for a Cure. They have held a garage sale and Family Field Day.

A portion of the proceeds will go to ALS research at the Program for Neurology Research & Discovery. For information, go to www.a2a3.org.


Stem Cells and Salads

Dr. Feldman with the hosts of the luncheon (from left): Pamela Applebaum, Susu Sosnick and Leslie Lewiston Etterbeek.

Along with co-hosts Susu Sosnick and Pamela Applebaum, Leslie Lewiston Etterbeek invited Dr. Feldman to her Bloomfield Hills home to talk to 45 guests on October 3 about stem cell research and the promise it holds for finding new treatments and cures for neurological disease.

Feldman explained what makes embryonic stem cells so special and the work she hopes to be able to do at the University of Michigan if such research became legal in the state. Just one month later, the voters of Michigan passed a new law lifting the ban on stem cell research.

 

 


Charity Event Par Excellence

League chairs are recognized at this year's tournament.

For the past seven years, the Executive Women's Golf Association of Metro Detroit has conducted an end-of-season tournament to raise money for the Program for Neurology Research & Discovery. This year’s event took place on September 25 at Twin Lakes Golf Club in Oakland Township.

Nearly 60 people teed off. The golfers, sponsors and a silent auction raised $2,400 for neurological research. The EWGA exists to provide a setting for women to learn to play and enjoy the game of golf for business and pleasure. The Metro Detroit Chapter has over 200 members in Oakland, Macomb, Wayne and Washtenaw counties.