- Intraventricular hemorrhage constitutes a serious cause of morbidity
and mortality in neonates. It occurs in 60-75% of 500-750 gram neonates
and 10-20% of 1,000-1500 gram neonates.
- According to Futagi et al, in those that experience any grade of hemorrhage,
only 56.1% of these babies have normal neurodevelopmental outcome, with
the rest having some degree of CP (22.4%), MR (10.2%) or borderline
intelligence (11.3%). Severity of outcomes increased with higher grade
of hemorrhage. Epilepsy occurred in 11.6% of infants with IVH.3
- These early studies show that blood collection from UACs affects the
cerebral hemodynamics; whether this is due to volume or velocity is
to be determined. Although no studies have been done on humans to directly
correlate these changes with IVH, there is no extra cost to being cautious
and sparing in our collection.
C, Huning B, Kaunicke M, Krug J, Horsch Sl. Umbilical artery catheter
blood sampling volume and velocity: Impact on cerebral blood volume
and oxygenation in very-low-birthweight infants. Acta Paediatrica,
G, Keller E, Haensse D, et al. Slow blood sampling from an umbilical
artery catheter prevents a decrease in cerebral oxygenation in the preterm
newborn. Pediatrics 2003;111: e73-6.
Y, Toribe Y, Ogawa K, Suzuki Y. Neurodevelopmental Outcome in Children
with Intraventricular Hemorrhage. Pediatr Neurol 2006;34: 219-24.