- Study population included only those willing to follow guidelines
of study - skews results given, this represents a motivated subset of
families, but may better represent those who would participate in an
- Study at tertiary referral center - results may not be reproducible
in primary care setting.
- Practical obstacles to office based MPT include time constraint,
family motivation and cooperation of parents, teachers and pharmacy.
- Patients at long term follow-up not compared to a control group.
- Unable to use study results to evaluate MPT as a prognostic indicator
indicator of methylphenidate use at long term follow-up because patients
treated differently based on MPT results.
Kent MA, Camfield CS, Camfield PR. Double-blind methylphenidate
trials: Practical, useful, and highly endorsed by families. Archives
of Pediatrics & Adolescent Medicine, 1999; 153(12):1292-1296.
Clinical Practice Guideline: Diagnosis and Evaluation of the Child With
Attention Deficit/Hyperactivity Disorder. Pediatrics, 2000;
Miller KJ. Attention deficit/hyperactivity disorders. Pediatrics
In Review, 1998; 19(11):373-384.