- It was noted in the Dykes study that the outcomes were statistically
significant in relation to severity of IVH and gestational age <30
- It does not appear that early removal of protein and blood from CSF
by serial lumbar punctures reduces morbidity/mortality in patients with
- Lumbar punctures have been shown effective in delaying the need for
shunt placement as the infant grows to a size acceptable for surgery.
- Incidence rate of meningitis in patients requiring serial lumbar punctures
has been reported as 5-15%.
Anwar M, Kadam S, Hiatt M, Heygi T. Serial lumbar punctures in
prevention of post-hemorrhagic hydrocephalus in pre-term infants.
Journal of Pediatrics, 1985; 170:446-450.
Dykes FD, Dunbar B, Lazarra A, Ahmann P. Post-hemorrhagic hydrocephalus
in high-risk pre-term infants: Natural history, management, and long-term
outcome. Journal of Pediatrics, 1989; 114:611-618.