- At 3, 6, and 12 months, more children improved in daily frequency of soiling with behavioral management in addition to intensive medical therapy than with intensive medical therapy alone (NNT ~ 3, Odds Ratio for no improvement at 12 months 0.20, 95% CI 0.06 to 0.65).1
- At 12 months, no significant differences were found among the three treatment groups in the number of children experiencing a cure (2 weeks free of soiling). (chisquare = 0.95, p = 0.7).
- Response to treatment during the first two weeks of therapy was highly predictive of outcome at 3, 6 and 12 months (P < 0.0001).
- Children receiving behavioral therapy in addition to medical management use significantly less laxative medication (P <0.04).