- Limitations of this study include patient population (adults only),
timing of measurements, low ultrafiltration rate (2L/hr)
- Despite these results, CRRT continues to show promise in the treatment
of sepsis in adults and children.2,3 More research involving multi-center,
prospective trials need to be performed to examine its role in immunomodulation
via blood purification irregardless of renal function in both children
L, Bellomo R, Hart G, Journois D, Davenport P, Tipping P, Ronco C. A
phase II randomized, controlled trial of continuous hemofiltration in
sepsis. Crit Care Med 2002;30:100-6.
JV, et al. Continuous veno-venous hemofiltration may improve survival
from acute respiratory distress syndrome after bone marrow transplantation
or chemotherapy. J Pediatr Hematol Oncol 2003;25:801-5.
C. Effects of different doses in continuous veno-venous haemofiltration
on outcomes of acute renal failure: a prospective randomised trial.