study done in Delaware at a pediatric ED from January to October.1
patients had WBC, band count, ANC, quantitative CRP, blood culture,
and urine obtained.
children from age 1 to 36 months with T>39 and no obvious source
(N=14) of the patients had SBI. UTI was the most common (6 patients).
level of <5 had a likelihood ratio (LR) of 0.09 for SBI (NPV of 98%);
thus, this could be useful in ruling out SBI.
level of >9 had a LR of 9.0 (PPV of 67%) for SBI.
ROC analyses, a CRP of 7 has a LR of 8.3, a WBC of 15 has a LR of 1.9,
and an ANC of 10.2 has a LR of 3.0.