studies have suggested that lower doses of dexamethasone (0.15mg/kg)
are as efficacious.
RCT shows oral prednisolone may be useful until a palatable and cost-effective
way to deliver dexamethasone is devised.
is approximately 10 times as potent as prednisolone, with a half-life
of 36-54 hrs vs.18-36 hrs for prednisolone.
KK, Ledwith CA. Outpatient treatment of moderate croup with dexamethasone:
intramuscular versus oral dosing. Pediatrics 2000; 106:1344-8.
TP. Glucocorticoids in the treatment of croup: barking up the right
tree. CMAJ 1998; 159:1121-2.
TP. Craig WR. Moher D. Osmond MH. Pasterkamp H. Sutcliffe T. Watters
LK. Rowe PC. Nebulized budesonide and oral dexamethasone for treatment
of croup: a randomized controlled trial. JAMA 1998; 279:1629-32.
JC, Klassen TP. “Croup”, Evidence Based Pediatrics and Child Health,
- See also
Steroids Are Effective in Croup.