Hyperbilirubinemia occurs in 30-60% of term infants, and is significant
(levels >13) in 3.5-12% of these children.
The sensitivity of transcutaneous bilirubin measurement using the BiliCheck(forehead)
vs. HPLC(gold standard) at higher levels (>17) is 50%, with a specificity
of 99%, giving a positive likelihood ratio (+LR) of 50 and a negative
likelihood ratio (-LR) of 0.5. When comparing the lab serum bilirubin
vs. HPLC, the sensitivity is 40% with a specificity of 98% which gives
a +LR of 20 and an -LR of 0.6.1
In this study, the mean error of BiliCheck compared with the mean error
of HPLC is independent of race, age, and birth weight.
Therefore, transcutaneous bilirubin measurement with the BiliCheck(forehead)
can not only be used as a screening tool, but also as a direct substitute
for serum lab bilirubin measurement.