Research
The division currently includes six clinical faculty members, four of whom are involved in NIH-funded research, two research-track basic science faculty and approximately 40 additional research, clinical and administrative staff members.
The Division is actively involved with clinical and basic science research. Recent work from members of the Division have included clinical publications on the use of mycophenolate mofetil in nephrotic syndrome, continuous renal replacement therapy and hemofiltration (CRRT) clearance in inborn errors of metabolism, and participation in numerous clinical trials in both hypertension and transplantation. In addition, collaborative efforts with Dr. Mueller in the College of Pharmacy on the clearance of drugs by CRRT are underway.
The basic science research activity of the Division is performed in four NIH-funded laboratories. Active areas of investigation include the characterization of regulators in the podocyte cytoskeleton during nephrotic syndrome (Drs. Smoyer and Ransom), identification of novel genes responsible for monogenetic renal disease (Drs. Hildebrandt and Otto), the study of transcription factors important in renal development (Dr. Brophy), and the study of podocalyxin in podocyte structure and function (Dr. Kershaw).
