Research
We are exploring a number of different areas of neonatal research including volume targeted and patient-triggered ventilation, developmental neurochemistry, ECMO, elements of chronic lung disease, nitric oxide therapy, and newer surfactant treatments. Our B.R.A.I.N. care program focuses on prevention and treatment of neonatal brain injury.
Strong collaborative ties exist with the Division of Pediatric Neurology, Division of Pediatric Pulmonology, the Department of Radiology, and the Department of Obstetrics. Fellows are exposed to significant research involvement during their training.
Our Faculty members are currently involved in these projects:
John D.E. Barks, M.D. (jbarks@umich.edu)
Division Director
- Impact of rewarming after therapeutic hypothermia in neonatal hypoxic ischemic encephalopathy
- Impact of neonatal seizures on cerebral metabolism: a near-infrared spectroscopy study
- Effects of Amplitude-Integrated EEG on Treatment of Neonates with Seizures
- Reliability and validity of the mN-PASS sedation subscale
- Auditory Temporal Processing in Pre-Term and Full-Term Infants
- Prophylactic Phenobarbital after Resolution of Neonatal Seizures
- Gene Targets for IVH
- Anticonvulsant Therapy to Improve Hypothermic Neuroprotection after Neonatal Ischemic Brain Injury
- Preclinical Evaluation of Long-Term Docosahexaenoic Acid (DHA) Treatment to Prevent Perinatal Hypoxic-Ischemic Brain Injury
Rachel L. Chapman, M.D. (rachellc@umich.edu)
Director, Neonatal-Perinatal Medicine Fellowship Program
- Development and maintenance of EBM skills across the educational continuum
- Self-Assessment and Relationship to Self-Directed Learning
- Utility of individualized learning plans across the educational continuum
- Evaluation of practice-based learning competency and relationship to curricular efforts
Karl Desch, M.D. (kdesch@umich.edu)
- Complex trait genetics focused on identification of the genetic determinants of traits related to thrombosis and hemostasis, common human traits and X-chromosome inactivation
- Genome-wide association studies
- Deep gene resequencing studies
- ADAMTS 13 gene sequencing in Familial Thrombotic Thrombocytopenic Purpura
- Informed consent process in minimal risk research
Steven M. Donn, M.D. (smdonnmd@umich.edu)
- Management of respiratory failure in preterm and term neonates, including newer modalities of ventilation, and real-time pulmonary graphic analysis
- Evaluation and comparison of different surfactant preparations
- Development of a synthetic, non-animal-derived surfactant
- Hypothermic neuroprotection following birth asphyxia
- Evaluation of near-infrared spectroscopy (NIRS)
- Medical liability and risk management in perinatal and neonatal practice
Naomi Laventhal, M.D. (naomilav@umich.edu)
- Clinical research ethics
- Neonatal ethics
Robert E. Schumacher, M.D. (neoschu@umich.edu)
Medical Director of the Holden NICU
- Efficacy of extracorporeal membrane oxygenation (ECMO) life support in premature and low birth weight infants
- Cognitive aspects of medical information needs
- Provision of “quality” in NICU
Mohammed A. Attar, M.D. (mattar@umich.edu)
- Pediatric education
- Mechanical ventilation
- Pulmonary response to treatment with surfactant
Subrata Sarkar, M.D. (subratas@umich.edu)
- Neuroprotective strategies for Perinatal Hypoxic-Ischemic Encephalopathy
- Temperature Monitoring during Brain Cooling
- Informed Choice for Medication use in Culturally Diverse Patients
- Intraventricular Hemorrhage and Post-Hemorrhagic Hydrocephalus
