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Opioid Medicines: Side Effects

Medication Types

NSAIDS
Opioids



Examples: morphine , hydromorphone (Dilaudid), oxycodone (Percocet, Tylox, Oxycontin), codeine (Tylenol #3), hydrocodone (Vicodin or Lortab)

Opioids are used for severe pain. They are available only with a doctor's prescription. Opioids come in many different forms: pills, capsules, liquids, rectal suppositories and injections.

HOW TO IDENTIFY AND MANAGE SIDE EFFECTS OF OPIOIDS

Constipation
There are several things you can do to prevent constipation:

  • You will probably need to take a laxative or other stool softener on a regular schedule to prevent constipation. Make sure your doctor or nurse gives you a list of appropriate laxatives to choose from. These medications are sold over the counter in a pharmacy, without a prescription.
  • Drink plenty of fluids, about 8 to 10 glasses each day. Some people find their bowels move after drinking hot liquids like coffee or hot lemon water. Prune and other fruit juices may be helpful.
  • Exercise daily. Take short walks. If you usually stay in bed or sit in a chair most of the time, do exercises while lying or sitting.
  • Tell your nurse or doctor if you are having problems with constipation, especially if you have not had a bowel movement in three days.

Nausea and Vomiting

  • Pain medicine may sometimes cause nausea or vomiting. These symptoms usually pass in a few days. Until then, it is often helpful to take a medicine to prevent nausea. Make sure you doctor gives you a prescription for this.
  • Taking your pain medicine with food will help decrease nausea.
  • Try to limit your intake to clear liquids when nauseated
  • If nausea or vomiting continues after a few days, tell your nurse or doctor.

Drowsiness

  • You can expect some degree of drowsiness when you begin taking an opioid. This feeling will often pass after 2-3 days. Do not do activities that require you to be alert, such as driving a car or operating machines.
  • Pain may keep you from resting well. Pain relief may allow your body to catch up on the rest you need. Thus, you may sleep more than usual. If you continue to feel sleepy after the first 2-3 days, notify your doctor or nurse.

Dry Mouth

  • Drink plenty of fluids
  • Take good care of your teeth and gums and rinse your mouth frequently.
  • Eating pineapple chunks, popsicles, shakes, yogurt, sugarless gum or hard sugarless candy may help moisten your mouth.

Difficulty Urinating

  • Difficulty urinating does not occur often in patients treated with pain medicine. If you have this side effect, give yourself plenty of time to urinate. Running water, drinking plenty of fluids, and setting aside time for urinating may help. If this problem continues, tell your nurse or doctor.

Confusion

  • Confusion, hallucinations, or nightmares may occur with pain medicine. This may be very frightening to you. Tell your nurse or doctor if you have any of these problems. They may want to change your medications.

Withdrawal

  • Opioids should not be stopped abruptly because uncomfortable withdrawal symptoms may occur. These symptoms may include shakiness, heart palpitations, sweating, and anxiety. Normally, opioids are slowly tapered over time if you do not need them anymore.

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