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March 26, 2001


A University of Michigan Health Minute update on important health issues

Women need testing and care for infection that can steal fertility, expert says

Chlamydia spreads fast and goes undetected, despite accurate new test and easy cure

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ANN ARBOR, MI - Every year, millions of American women get a sexually transmitted disease that they may never know about - until they try to get pregnant and find they can't, or develop chronic pelvic pain that haunts them for life.

That's why it's crucial for women of all ages to get tested for chlamydia even if they don't have symptoms, to get treated right away with antibiotics if they have it, and to take precautions such as using condoms whenever they have sex, says a University of Michigan Health System expert. These steps are especially important for sexually active women under 25, who have the highest risk of infection - and the most to lose.

The same advice of testing, treatment and protection goes for men, who bear the blame for passing chlamydia to their partners, says Mark Pearlman, M.D., an associate professor in the Departments of Obstetrics & Gynecology and Surgery who studies gynecological infections.

"Chlamydia is the most common sexually transmitted infection in the United States, with about four million cases a year. Everyone who has sex can have chlamydia," says Pearlman. "Compare that with a million cases of gonorrhea , and 500,000 cases of genital herpes, a year."

Besides the title of most common STD, chlamydia bears another, even more serious crown, says Pearlman. "It can be extraordinarily dangerous in terms of a woman's future reproductive health - it's the most common cause of infertility in the United States," he says.

In those who do become pregnant despite the infection, their pregnancy is very likely to be ectopic, or outside the uterus, putting the mother's life in danger, says Pearlman. Even if the pregnancy is normal, the baby's eyes and lungs can become infected at birth.

Luckily, UMHS and other health care providers are making it easier for women and men to find out if they have chlamydia, using a recently introduced urine test that is easier to take and more precise than other tests because it detects chlamydia bacteria through DNA analysis. If the test is positive, a 10-day course of antibiotics can clear up the infection and prevent complications.

But it's those women who don't get tested who worry Pearlman and other health experts the most. Chlamydia infections often lurk undetected because they don't cause symptoms, even while they're permanently harming a woman's reproductive system.

"We think that about two-thirds of the time there are no symptoms with this infection," Pearlman explains.

Even if symptoms do appear, women may ignore them. That's a mistake, because vaginal discharge, pain or bleeding during and after sex, abdominal pain and fever can all signal an infection of the cervix that could later go "underground" and cause more damage further up in the woman's reproductive system. The infection could also progress immediately to sepsis and even form a painful abscess that only surgery can fix. Any woman experiencing such signs should consult her doctor or other health care advisor and seek testing.

A long-term infection by Chlamydia trachomatis bacteria is what can lead to lasting harm, Pearlman continues. The infection is a leading cause of pelvic inflammatory disease, or PID, a chronic condition that often causes lower abdominal pain but can also lurk in a woman's system without symptoms, blocking the Fallopian tubes. About 40 percent of untreated chlamydia infections lead to PID, according to the Centers for Disease Control and Prevention.

"When PID is symptomatic, it can be diagnosed and treated," Pearlman says. "But nearly two-thirds of the time the symptoms aren't present, and women only find out they've had it years later when they have blocked tubes and have difficulty getting pregnant, or do get pregnant and have a tubal, or ectopic, pregnancy."

The CDC estimates that one in five women with PID will become infertile, and almost as many will experience debilitating pelvic pain. One in 10 will have a life-threatening tubal pregnancy.

As for men, the physical result of a chlamydia infection may be pain during urination or discharge, and perhaps some sensitivity in the testicles. But even more, men bear the psychological burden of knowing they can harm their partner by passing along an undetected infection. "Men who are sexually active, particularly young men who are, should consider getting a chlamydia test and have a discussion with their health care provider," says Pearlman.

Men who don't know if they or their partners are infected should wear a condom during sex, though condoms are not 100 percent effective in preventing any infection. "Regular and proper use of condoms can significantly reduce the likelihood of a chlamydia infection, and that's true for gonorrhea and HIV too," says Pearlman. "So, routine condom use at the time of sexual intercourse is a good preventive measure."

Even with precautions, regular discussion with a doctor or health care professional, and regular testing, are vital for any sexually active person. Anyone under 25 years of age who has had sex with one or more people should be extra careful, as chlamydia infection is most common in the teen and young adult years. In fact, of the 23,107 cases reported in Michigan in 1999, 7,486 cases - almost 40 percent - were in young women aged 15 to 19.

Women don't have to submit to a swab test of the cervix anymore if they want to find out if they're infected, Pearlman adds.

"In the last few years simple urine testing has become available, and it's just as reliable as the cervical testing, in some cases more reliable," he says. "It's sensitive, meaning it picks up most cases, and it's specific, which means that if the test comes back positive you can rely on the result." But just as with the older test, women need to talk with their health care providers to ask for the test, or discuss whether it might be needed because of their sexual history or pregnancy plans.

Facts about chlamydia infection:

  • Chlamydia is a sexually transmitted disease caused by a bacteria. It can infect and be spread by men and women alike.
  • An estimated 3 million to 4 million chlamydia infections occur each year, with about 2 million people carrying the disease at any given time.
  • Because many people become infected without knowing it, and never get tested, only about 660,000 cases were found in 1999, the most recent year for which numbers are available.
  • Michigan has required reporting of chlamydia since 1992. Compared with the rest of the U.S., Michigan's chlamydia rates are about average, with 23,107 cases reported in 1999.
  • Forty percent of Michigan's cases in 1999 were in teen girls aged 15 to 19. In Washtenaw County alone, 79 percent of cases detected in 1999 were in people aged 24 or younger.
  • Two-thirds of women and half of men infected with chlamydia will not experience symptoms.
  • Forty percent of untreated chlamydia cases in women will lead to pelvic inflammatory disease, or PID. Two-thirds of PID cases don't cause symptoms, but the remaining 20 percent will suffer chronic pelvic pain. Twenty percent of women with PID will lose fertility.
  • Chlamydia costs the United States economy $2 billion each year in direct and indirect costs.
  • The U-M Health System offers a new test for chlamydia that doesn't involve a cervical swab. Instead, women and men can have their urine tested with a more accurate DNA analysis. UMHS also tests pregnant women for chlamydia before they give birth, to protect the baby.

Find out more on the World Wide Web and via phone:

American Social Health Association - Chlamydia

Centers for Disease Control: Chlamydia

or call the

CDC Sexually Transmitted Disease hotline, (800) 227-8922.
Trained health professionals are available to answer your questions and provide referrals 24 hours a day, 7 days a week. All calls are private, personal and confidential.

Written by Kara Gavin

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