Michigan Video Abstracts

Current and legacy contributions to biomedical research from the University of Michigan

Video Library

Current and Cutting-edge Research

A major focus of Michigan Video Abstracts (MVA) is current and cutting-edge research. A key emphasis is on collaborative and multidisciplinary work, which we hope will motivate others to move in this direction.

Edward Domino, M.S., M.D.
Rapid Antidepressant Actions of Special K: Toward a New Pharmacotherapy of Depression
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Current antidepressant medications work, but not for everyone. Also, when the medications do work, it can take a month or more for patients to experience a significant antidepressant effect. However, there is hope for those that need a fast-acting alternative. In this video, Edward Domino, M.S., M.D. provides an overview of a substance known as ketamine (street name: "Special K") and how it is used to treat depression. He describes the pros and cons of using ketamine as an antidepressant and suggests future directions researchers might take to improve its therapeutic effectiveness.

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Michael D. Fetters, M.D., M.P.H., M.A.
Part 1:
The Mixed Methods Research Integration Trilogy and Its Dimensions
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Dr. Fetters provides a conceptual overview of the mixed methods approach to research. He outlines the three key facets of the mixed methods integration trilogy: philosophical, methodological, and methods aspects and how to integrate them in research design. "Mixed methods researchers unite the strengths of both qualitative and quantitative research....That is, when you bring together the qualitative approach 'one' with a quantitative approach 'one', mixed methods researchers strive to achieve a sum of three, something greater than the value of the individual parts." - Michael D. Fetters, Professor of Family Medicine and Co-Director of the Michigan Mixed Methods Program.

Original Manuscripts: Dr. Michael D. Fetters on Social Media:
Michael D. Fetters, M.D., M.P.H., M.A.
Part 2:
The Integration Trilogy and Its Dimensions: Getting Down to Details
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In this video, Dr. Fetters provides an in-depth description of the three key aspects of integration theory and how the researcher should attend to each in their work. "So, what is the research integration trilogy? The mixed methods research integration trilogy symbolizes how all dimensions of the mixed methods research approach can be integrated. So, simply speaking, that's bringing together the philosophical, methodological, and methods...of the mixed methods research trilogy". - Michael D. Fetters, Professor of Family Medicine and Co-Director of the Michigan Mixed Methods Program.

Original Manuscripts: Dr. Michael D. Fetters on Social Media:
Timothy Guetterman, Ph.D., M.A.
Virtual Humans Help Aspiring Doctors Learn Empathy
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Dr. Timothy Guetterman shares his team's research on the use of virtual humans to assess medical resident’s communication skills. He describes the development of virtual human technology and the results of the study. This is one of the first studies in the nation to use virtual humans to assess communication skills. "I'm a research methodologist, which means I study how we do research, and I'm interested in health communication, and how we can better train people to communicate in the healthcare setting, and also how we can measure that. I think this research is really interesting because we're using virtual humans - this advanced technology where you can not only hear ways to communicate, but you can actually practice and interact with a virtual human."" - Timothy Guetterman, Assistant Professor, Department of Family Medicine.

Original Manuscript: Learn More Dr. Timothy Guetterman on Social Media:
Melvin McInnis, M.D.
The Study of Bipolar Disorder is the Study of Humanity
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"I personally love engaging and working with people that have bipolar disorder. I think it's one of the most rewarding fields of medicine to study, and I feel incredibly privileged to study this illness" - Dr. Melvin McInnis, Research Director, Heinz C. Prechter Bipolar Research Fund.

In this video, Dr. McInnis discusses how he collaborates with scientists across disciplines to develop new models to understand and treat bipolar disorder. He shares key insights gained from various research projects involving stem cells, mobile technologies, and the microbiome.

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Michelle A. Meade, Ph.D.
Development & Evaluation of SCI Hard - a Gaming App to Promote Self-management of Spinal Cord Dysfunction
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Learn about SCI Hard, a healthcare gaming app developed at the University of Michigan to help adolescents and young adults with spinal cord injury and dysfunction (SCI/D) to apply self-management skills. In this presentation, psychologist Michelle A. Meade, Ph.D., one of the creators of the game, describes its features, why and how it was designed, and the research to evaluate its effectiveness. Video recordings from the game are used to illustrate key components of SCI Hard.

Dr. Meade is a psychologist and associate professor of Physical Medicine and Rehabilitation at the University of Michigan. Her primary research interests focus around patient self-management, participation and health improvement, and reduction of costs and healthcare disparities for individuals with disabilities.

Learn More Dr. Michelle Meade on Social Media:
Johmarx Patton, M.D., M.H.I.
"What? So What? Now What?" - An Educational Perspective on the Learning Health System
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"People talk about the Learning Health System, but what is it really? The goal of the Learning Health System is to not only to put actionable knowledge in the right person's hands at the right time to make an informed decision, but also to take advantage of the ever-increasing volume of patient data that's being generated as health care becomes more and more digital." - Johmarx Patton, M.D., M.H.I.

In this video, Dr. Johmarx Patton describes his vision of the Learning Health System (LHS), with particular emphasis on impact of the LHS on the education of medical students and residents. He identifies opportunities that the LHS will provide to learners and educators to empower them to improve education and health care. He also voices important questions that will need to be answered before leadership can move fully forward with implementing possible capabilities of the LHS.

Learn More Dr. Johmarx Patton on Social Media:
Michael Sabel, M.D.
Cancer Ally: Improving Patient Care with Mobile Apps
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Cancer Ally, is a suite of mobile apps developed by Dr. Michael Sabel, Chief of Surgical Oncology to help patients navigate the complexities of multidisciplinary cancer care.

In this video, Dr. Sabel discusses problems patients often have when getting treated for cancer (e.g., difficulty following complex treatment plans, scheduling appointments, getting questions answered, and providing accurate information about their symptoms to their physicians). He then describes the suite of apps he has created to address these problems to improve patient care.

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Shashank S. Sinha, M.D., MSc
The Changing Face of Critical Care Cardiology
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It's not your father's coronary care unit anymore. Which patients comprise the modern cardiac intensive care unit (CICU)?

In this video, Dr. Shashank Sinha examines comprehensive national data on the number, types and outcomes of patients admitted to CICUs over the past decade. Temporal trends demonstrate a rise in primary non-cardiac diagnoses, leading to important training and staffing implications.

Original Manuscript: Digital Learning Tools: Press Release: Dr. Shashank Sinha on Social Media:

Contributions to Knowledge

MVA also showcases the work of emeritus and senior UM faculty who have made substantial "contributions to knowledge" during the course of their careers. We use the interview format to allow these giants to share their insights, experience, and wisdom.

Robert Bartlett, M.D.
It's All About the Patient
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"You can't think about legacy. You're just thinking about what am I doing today? Who do I have to operate on next week? Can I take good care of my patients? Can I keep the lab running?" - Dr. Robert Bartlett.

In this video, Medical Student Rana Kaber, interviews Dr. Bartlett about his distinguished career as a surgeon and innovator (e.g., inventing extracorporeal membrane oxygenation (ECMO), pioneering the development the critical care unit, etc.). Dr. Bartlett shares highlights of his career, his approach to overcoming the hurdles he faced as an innovator, and what motivates him to continually develop new approaches to patient care.

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Roy Davage Hudson, Ph.D.
Career and Life Advice to Young Scientists
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"Well, the first thing I'd say [is] that you're not an island unto yourself. We're family, and we need each other. And we need to have a sensitivity in terms of, what is it I'm about to do, and what if that were done to me? What would be my response? And so, ...we are our brother's keeper, and we should function in the world in that manner." - Roy Davage Hudson, Ph.D., the first African-American to earn a Ph.D. in pharmacology from the University of Michigan.

In this interview segment, Dr. Hudson looks back on his life and career in science and education to provide guidance and perspective to young people embarking on their careers.

Roy Davage Hudson, Ph.D., has a long list of accomplishments to his name: first African-American to earn a pharmacology degree from the University of Michigan, Danforth Foundation fellow, Brown University Graduate School assistant dean, president of Hampton University, and more.

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Roy Davage Hudson, Ph.D.
Reflections on a Career in Science and Leadership
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In this interview, Roy Davage Hudson, Ph.D., shares his life events and lessons learned pertaining to his long career in academia and the pharmaceutical industry.

Dr. Hudson was the first African-American to receive a Ph.D. in pharmacology from the University of Michigan. He has had a long and industrious career in academic medicine and the pharmaceutical industry.

Table of Contents
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Benedict R. Lucchesi, M.D., Ph.D.
The Problem of the Stone Heart
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When Ben Lucchesi was a young medical/Ph.D. student he witnessed a patient die on the operating table because his "heart turned into a rock". He left the operating room that day, determined to find out why.

In this video, Dr. Benedict Lucchesi describes how he, as a dual medical/Ph.D. student in pharmacology, took it upon himself to solve the problem of the stone heart after assisting on a surgery in which the patient died. Because of Dr. Lucchesi's work, open heart surgery is much safer today. Join Dr. Edward Domino as he interviews Dr. Lucchesi about his research discovery.
James O. Woolliscroft, M.D.
Caring for and Learning from Patients
Watch Video 3:39
What Led You to a Career in Medicine and Education?
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Big Data vs. the Physiologic Model of Medicine
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A New Medical School Curriculum
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Leadership and Change Management
Watch Video 4:39
What is Your Advice to Young People?
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"One patient... [had] bad sarcoid, so I was going through the complications. And he stopped me, because I said, 'You know, there's a five percent chance of this, a three percent of this, a seven whatever'. He said, 'No, no, no, no. It's zero or one. For me, I get it, I don't. I get the complication, I don't. I live, I die. It's zero or one.' That was really, that was a very powerful lesson to me." "Caring for and Learning from Patients" - Dr. James O. Woolliscroft, Lyle C. Roll Professor of Medicine, Professor of Internal Medicine and Learning Health Sciences, former Dean of the University of Michigan Medical School (2006-2015).

In this collection of interview segments, Dr. Woolliscroft shares experiences and insights gained from a career in academic medicine. Topics range from treating patients to leadership to the future of medicine.

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