Michigan Video Abstracts

Current and legacy contributions to biomedical research from the University of Michigan

Featured Author

Current and Cutting-edge Research
Virtual Humans Help Aspiring Doctors Learn Empathy
Timothy Guetterman, Ph.D., M.A.
Dr. Timothy Guetterman shares his team's research on the use of virtual humans to assess medical residents' communication skills. He describes the development of virtual human technology and the results of the study. This is one of the first studies in the nation to use virtual humans to assess communication skills.
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"I'm a research methodologist, which means I study how we do research,...I'm interested in health communication and how we can better train people to communicate in the healthcare setting and also how we can measure that. I think this research is really interesting because we're using virtual humans —this advanced technology where you can not only hear ways to communicate, but you can actually practice and interact with a virtual human." —Timothy Guetterman, Assistant Professor, Department of Family Medicine.

Original Manuscript: Learn More: Dr. Timothy Guetterman on Social Media:

Mission

Our mission is to inspire scientists, researchers, and the public by sharing innovative bioscience research from the University of Michigan. We use short video interviews and presentations to make the ideas accessible and introduce the people behind the work.

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Recent Releases

Current and Cutting-edge Research
Rapid Antidepressant Actions of Special K: Toward a New Pharmacotherapy of Depression
Edward Domino, M.S., M.D.
Current antidepressant medications work, but not for everyone. Also, when the medications do work, it can take a month or more for patients to experience a significant antidepressant effect. However, there is hope for those who need a fast-acting alternative.
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In this video, Edward Domino, M.S., M.D., provides an overview of a substance known as ketamine (street name: "Special K") and how it is used to treat depression. He describes the pros and cons of using ketamine as an antidepressant and suggests future directions researchers might take to improve its therapeutic effectiveness.

References Cited:
  • Berman et al. Antidepressant effects of ketamine in depressed patients. Society of Biological Psychiatry. 2000; 15;47(4):351-4. Retrieved from Link
  • Zarate et al. A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression. Archives of General Psychiatry. 2006; 63(8):856-64. Retrieved from Link
  • Domino et al. Taming the ketamine tiger. classic papers revisited. Anesthesiology 2010; 113(3): 678-686. Retrieved from Link
  • Hasslemann et al. Ketamine as antidepressant? Current state and future perspectives. Current Neuropharmacol. 2014; 12(1):57-70. Retrieved from Link
  • Sanacora et al. A Consensus Statement on the Use of Ketamine in the Treatment of Mood Disorders. JAMA Psychiatry. 2017; 74(4):399-405.
  • Domino EF (ed): Status of Ketamine in Anesthesiology (Ann Arbor, MI: NPP Books, 1990), pp. 1603. Retrieved from Link
  • Jansen K. Ketamine: Dreams and Realities. Sarasota, FL : Multidisciplinary Association for Psychedelic Studies. 2001. ISBN-10: 0966001974. Retrieved from
  • Yew DT. Ketamine: Use and Abuse. Published by CRC Press, NY. 2015. ISBN: 9781466583399
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Current and Cutting-edge Research
Part 1:
The Mixed Methods Research Integration Trilogy and Its Dimensions
Michael D. Fetters, M.D., M.P.H., M.A.
Dr. Fetters provides a conceptual overview of the mixed methods approach to research. He outlines the three key facets of the mixed methods integration trilogy: philosophical, methodological, and methods aspects and how to integrate them in research design.
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"Mixed methods researchers unite the strengths of both qualitative and quantitative research....That is, when you bring together the qualitative approach 'one' with a quantitative approach 'one', mixed methods researchers strive to achieve a sum of three, something greater than the value of the individual parts." - Michael D. Fetters, Professor of Family Medicine and Co-Director of the Michigan Mixed Methods Program.

Original Manuscripts:
  • Fetters MD, Molina-Azorin JF. The Journal of Mixed Methods Research starts a new decade: The mixed methods research integration trilogy and future directions. JMMR, 11(3):291-307, 2017. Retrieved from Link
  • Fetters MD, Freshwater D. The 1 + 1 = 3 integration challenge. JMMR 9(2): 115-7, 2015. Retrieved from Link
  • Fetters MD. "Haven't we always been doing mixed methods research?": Lessons learned from the development of the horseless carriage. JMMR 10(1): 3-11, 2016. Retrieved from Link
Dr. Michael D. Fetters on Social Media:
Contributions to Knowledge
The Problem of the Stone Heart
Benedict R. Lucchesi, M.D., Ph.D.
When Ben Lucchesi was a young medical/Ph.D. student he witnessed a patient die on the operating table because his "heart turned into a rock". He left the operating room that day, determined to find out why.
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In this video, Dr. Benedict Lucchesi describes how he, as a dual medical/Ph.D. student in pharmacology, took it upon himself to solve the problem of the stone heart after assisting on a surgery in which the patient died. Because of Dr. Lucchesi's work, open heart surgery is much safer today. Join Dr. Edward Domino as he interviews Dr. Lucchesi about his research discovery.

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Current and Cutting-edge Research
Part 2:
The Integration Trilogy and Its Dimensions: Getting Down to Details
Michael D. Fetters, M.D., M.P.H., M.A.
In this video, Dr. Fetters provides an in-depth description of the three key aspects of integration theory and how the researcher should attend to each in their work.
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"So, what is the research integration trilogy? The mixed methods research integration trilogy symbolizes how all dimensions of the mixed methods research approach can be integrated. So, simply speaking, that's bringing together the philosophical, methodological, and methods...of the mixed methods research trilogy". - Michael D. Fetters, Professor of Family Medicine and Co-Director of the Michigan Mixed Methods Program.

Original Manuscripts:
  • Fetters MD, Molina-Azorin JF. The Journal of Mixed Methods Research starts a new decade: The mixed methods research integration trilogy and future directions. JMMR, 11(3):291-307, 2017. Retrieved from Link
  • Fetters MD, Freshwater D. The 1 + 1 = 3 integration challenge. JMMR 9(2): 115-7, 2015. Retrieved from Link
  • Fetters MD, Curry LA, Creswell JW. Achieving integration in mixed methods designs – principles and practices. Health Serv Res, 48(6 Pt 2): 2134-56, 2013. Retrieved from Link
Dr. Michael D. Fetters on Social Media: