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Animal Phenotyping

Michigan Metabolomics and Obesity Center (MMOC)
Michigan Diabetes and Research Training Center (MDRTC)


Goals

MiniSpec

To advance research in the area of diabetes and obesity by providing experimental tools to the scientific community for phenotyping rat and mouse models of diabetes, obesity and related metabolic disorders.

Broaden the scope of techniques available to individual investigators.

Standardize methodologies related to metabolic phenotyping.

Bring together the multidisciplinary investigators at the University to apply and develop new in vivo and in vitro

techniques to assess metabolism in rats and mice.

Coordinate interactions among university researchers interested in metabolic diseases.

Compile a database for rodent models of diabetes and obesity.

 

Services

I. Surgery Procedure
1. Vascular and organ catheterization
2. Other surgeries can also be arranged with us


II. Insulin Sensitivity and Substrate Metabolism
1. Glocuse tolerance tests
2. Hyperinsulinemic-euglycemic clamps
3. Triglyceride/fatty acid cycling (to be developed)

III. Energy Expenditure and Spontaneous Activity
1. VO2 and VCO2
2. Spontaneous activity
infrared photo-beam detection in isolated chambers
gravimetric detection in home cages
3. Food consumption and feeding bouts
4. Body composition (for conscious animals)

IV. Radio-telemetry Blood Pressure Measurement (rat)

V. Aerobic Exercise (rat)

VI. In Vitro Metabolism (to be developed)

VII. Research Assistance

VIII. Other Procedures


CONTACT US
Life Sciences Institute, Room 3338
210 Washtenaw Ave., Ann Arbor, MI 48109-2216
Tel: 734.764.7043 (Nathan Qi)
Fax: 734.763.6492


Listed rates are for University of Michigan MMOC members. If you are not currently a member,
click here to complete our membership application.

Prices for external customers vary. 30% overhead must be included for all external customers. Please contact Nathan Qi regarding availability.

A signed service agreement and hard copy of purchase order must be obtained from each outside customer. Sample service agreement.

For external animal shipping information, please contact ULAM office.
Quarantine period of 8-10 weeks is required unless proof of the following tests can be confirmed:
Mice: pinworms, MHV, MPV, MVM, NS-1, EDIM, Ectromelia, Sendai, PVM, TMEV (GDVII), REO, MPUL, LCMV, MAV, and POLY
Rats: pinworms, SDAV, KRV, H-1, RPV, NS-1, Sendai, PVM, REO, MPUL, TMEV, LCMV, MAV