Faculty Research Interests

Vernon Carruthers , Ph.D.

Pathogenesis of parasitic infections: Mechanisms of cell invasion and survival during infection

Marilia Cascalho, MD

DNA mutators and tumorigenesis or immunoglobulin gene diversification; mutable vaccine; B cell memory, B and T cell repertoire; transplantation

Cheong-Hee Chang, Ph.D.

Regulation of the effector function of CD4 T cells and dendritic cells

Kathleen Collins, MD, Ph.D.

Molecular mechanisms of HIV immune evasion

Victor DiRita, Ph.D.

Genetic and molecular studies of host-microbe interactions

Wesley Dunnick, Ph.D.

Immunoglobulin genes; DNA rearrangement

Kathryn Eaton, DVM, Ph.D.

Immunopathogenesis of Helicobacter pylori

N. Cary Engleberg, MD

Pathogenesis of Legionnaires' disease; molecular mechanisms of intracellular infection

David I. Friedman, MD

Regulation of gene expression; role of phage in toxin expression

A. Oveta Fuller, Ph.D.

Human virus entry, pathogenesis and infection preventions

Philip Hanna, Ph.D.

Anthrax molecular pathogenesis and host responses; macrophage-mediated inflammation

Yongqun “Oliver” He

Brucella-Host Interaction and Bioinformatics

Gary Huffnagle, Ph.D.

Pulmonary immunology; fungal pathogenesis and microflora-mediated modulation of immunity

Michael J. Imperiale, Ph.D.

Virus-host interactions in healthy individuals and transplant patients; virus assembly

Philip D. King, Ph.D.

Signal integration in T cells

Denise Kirschner, Ph.D.

Host pathogen interactions during persistent infections

Eric Krukonis, Ph.D.

Bacterial pathogenesis; regulation of bacterial virulence in response to environmental cues

Yasmina Laouar , Ph.D.

Immunology/Mechanisms of Immunosuppression

Gary D. Luker, MD

DNA virus and cancer cell pathogenesis; non-invasive image analysis of signaling pathways and disease in living mice

Eric Martens, Ph.D.

Microbial degradation of complex carbohydrates in the human distal gut

David J. Miller, MD, Ph.D.

Host-pathogen interactions in viral RNA replication

Harry L. T. Mobley, Ph.D.

Bacterial pathogenesis; virulence of uropathogens and Helicobacter pylori

Akira Ono, Ph.D.

HIV-1 replication and host cellular membranes

Mary O'Riordan, Ph.D.

Host and bacterial adaptation to intracellular infection

Howard Petty

Inflammatory processes within the eye; high-speed microscopy for investigation of metabolic and other activity

Jeffrey Platt, MD

Transplantation Immunology, stem cell-immune system interaction, genomic stability, accommodation in transplantation and host defense

Malini Raghavan, Ph.D.

Molecular interactions in antigen presentation and host responses to virus infections

Pat Schloss, Ph.D.

Analysis of host-microbiome interactions; computational microbial ecology

Maria Sandkvist, Ph.D.

Bacterial pathogenesis: Molecular mechanism of extracellular protein secretion

David H. Sherman, Ph.D.

Molecular genetic, biochemical and bioorganic chemical studies of microbial natural product biosynthesis

Katherine Spindler, Ph.D.

Molecular pathogenesis and host susceptibility genetics of virus infections

Joel Swanson, Ph.D.

Regulation of endocytosis and the cytoskeleton in macrophages

Michele Swanson, Ph.D.

Growth of Legionella pneumophila in macrophages

Alice Telesnitsky, Ph.D.

Mechanisms of murine leukemia virus and HIV-1 genetic variation

Jason Weinberg, MD

Pathogenesis of persistent viral infections

Christiane Wobus, Ph.D.

Mechanisms of norovirus entry into host cells in vitro and in vivo

Vincent Young MD, Ph.D.

Bacterial pathogenesis of gastrointestinal infectious disease. Microbial ecology of the gastrointestinal tract

Don B. Clewell, Ph.D.

Enterococcal plasmids and transposons

Stephen Cooper, Ph.D.

Analysis of regulation of the eukaryotic cell cycle

David I. Friedman, MD

Regulation of gene expression; role of phage in toxin expression

Elloit Juni, Ph.D.

Molecular taxonomy of the Moraxellaceae

Frederick C. Neidhardt, Ph.D.

Bacterial growth physiology; molecular biology of gene expression

Steven King, Research Assistant Professor

Retrovirus replication and recombination

Adam Hoppe,
Research Investigator

Imaging signaling networks regulating vesicular traffic in yeast and macrophages

My-Hang (Mae) Huynh
Research Investigator

Biology of Toxoplasma infections.

Simeone Marino, Research Investigator

Mathematical modeling of host-pathogen interaction in Mycobacterium tuberculosis infection

Syed Monem Rizvi,
Research Investigator

Glycoprotein E and cell-to-cell spread of Herpes simplex virus type 1