M1 Sequence Overview
Renal
Sequence Director

Tamara Stein, M.A.
Lecturer, Medical Education
Email: tastein@umich.edu

Sequence Description

The objective of this sequence is to obtain, synthesize, and apply information regarding the normal structure and function of the renal system. By the end of the sequence, students will have acquired a working knowledge of

  1. the structural components of the kidney and how each is specialized for its function of processing filtrate and producing urine;
  2. the homeostatic mechanisms involved in the control and regulation of fluid, electrolyte, and acid-base balance; and
  3. how nitrogenous waste is eliminated.

Studying normal structure and function provides a basis for understanding pathologic changes and physiologic consequences of these changes, and to this end; clinical problems related to various pathophysiologic conditions in the renal system are discussed in this sequence. The sequence also includes a multidisciplinary conference and a small group session addressing the clinical consequences of water/electrolyte balance and acid/base problems. More specific objectives and expected learning outcomes for each lecture and lab are provided in each session. Access to series of current reviews and/or state of the art manuscripts of relevant renal function are provided as part of encouraging continuous learning in the changing field of science.

The small group discussion session in the sequence provides students with an opportunity to discuss, analyze, and interpret signs and symptoms as they relate to the underlying physiological principles learned. The purpose of this session is not to diagnose specific diseases, but to provide practice in applying physiological principles to interpreting various pathophysiologic states.