M1 Sequence Overview
Cells & Tissues
Sequence Director

Audrey Seasholtz, Ph.D.
Professor, Biological Chemistry; Research Professor, Molecular and Behavioral Neuroscience Institute, Associate Research Professor, Reproductive Sciences Program
Email: aseashol@umich.edu

Sequence Description

Mission Statement
The Cells and Tissues sequence introduces the common biochemical, cellular, and molecular processes present in all organ systems and the major cell and tissue types present in organs. This sequence also introduces anatomical dissection to students. Multidisciplinary conferences and clinical correlates integrate the functions of the normal cells and tissues with clinical applications.

Knowledge

  1. Each student will be able to apply the basic principles of protein structure and function and the basics of protein enzymology to their analysis of the mechanisms of normal and disease states.
  2. Each student will be able to distinguish between the different intracellular trafficking processes for synthesis and localization of proteins to their appropriate sites within the cell or for secretion from the cell.
  3. Each student will be able to differentiate the major receptor classes and the corresponding intracellular signaling pathways.
  4. Each student will recognize the basic properties of membranes and membrane potentials and be able to apply these properties to membrane transport and membrane electrophysiology, especially as they apply to muscle and neuronal function.
  5. Each student will be able to distinguish the biochemical, molecular and cellular properties of cytoskeleton and extracellular matrix and their functions in epithelium, connective tissue, muscle and nervous tissue.
Skills
  1. Become proficient at recognizing the major cell types and tissues in the body.
  2. Become proficient at anatomical dissection and recognition of anatomical structures.
Professionalism
  1. Approach human dissection with commitment to learning and respectful treatment of body donors.