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JUNE 2011, Vol. 29

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HEADLINES

Gregory Wolf to Receive the Distinguished Faculty Lectureship Award in Biomedical Research – August 8, 2011
Gregory T. WolfGregory T. Wolf, M.D.

The Biomedical Research Council (BMRC) has the honor of selecting a faculty member for the Distinguished Faculty Lectureship Award in Biomedical Research each year. This award, which was initiated in 1979, continues to be the highest research honor bestowed by the Medical School upon a faculty member in the biomedical sciences. Each recipient has made outstanding contributions in the areas of research, teaching, and institutional service.

Dr. Gregory Wolf, a pioneer in head and neck cancer treatment, has been chosen to receive the Dean’s 2011 Distinguished Faculty Lectureship Award. Dr. Wolf is Professor and Chair Emeritus of the Department of Otolaryngology. In addition to being one of the top surgical oncologists in the world, Dr. Wolf is a leading scientific investigator who has played a pivotal role in advancing the field of biomedical research, cancer immunology, and laryngeal preservation cancer. Dr. Wolf’s novel discoveries in cancer biology challenged the status quo, such as the widespread practice of routine larynx removal in patients with advanced cancer. His tested treatment paradigms – now adopted around the world – allow patients with advanced cancer to retain affected organs, maintain crucial functional capacities, avoid disfiguring surgical defects, and enjoy a higher quality of life than previously possible. Currently he is the PI of the U-M Head and Neck NIH SPORE (Specialized Program of Research Excellence) grant, which continues to advance treatments for head and neck cancer patients. During the 16 years when Dr. Wolf was Chair of the Department of Otolaryngology - Head and Neck Surgery at the UMMS, the Department was consistently among the highest ranked units in the School. In addition to his groundbreaking work in organ sparing therapy and his administrative contributions, Dr. Wolf has been a prolific writer (over 200 articles) and mentor to many.

Please join us for Dr. Wolf’s award presentation, lecture and reception on August 8, 2011 at 4:00 PM in the Taubman BSRB Auditorium. Dr. Wolf’s lecture will be on “Changing Treatment Paradigms in Head and Neck Oncology.”

New Website Is Front Door to Science, Health, and Medicine Publishing Services

Scientific and medical publishing is in a very dynamic state — things are changing rapidly — and that provides for new and exciting opportunities to maximize the visibility and distribution of scientific and medical information. As publishing moves away from the traditional book and journal formats, the content itself becomes much more important than the vehicle by which it is published. This provides authors with more opportunities to disseminate content and data in novel ways. To help faculty, researchers, and students in the U of M Health System achieve their publishing goals, the Medical School provides Health Sciences Publishing Services to assist in navigating the wide array of opportunities, resources, and services that are available to them.

Health Sciences Publishing Services provide two forms of support for those looking to publish their research results or an article: an informational website and individual consultation services. The website provides a wealth of information about publishing options, opportunities, and resources, both within U-M and externally. The one-on-one consultation services are provided by Jasna Markovac, Senior Advisor for Publishing and Related Business Development at the Medical School. Jasna is trained in life science (Ph.D. Human Genetics, U-M) and, after several years in academics, changed careers to join the Science Technical Medical publishing industry. For the past three years, she has worked for the University of Michigan, first at MLibrary, and more recently at the Medical School, focusing on academic publishing initiatives, exploring new publication opportunities, and providing consultation services to the faculty, staff, and students for all aspects of the publishing process.

If you need help deciding how to publish, where to publish, or even whether to publish — Health Sciences Publishing Services can help you choose the best vehicle for maximum visibility and distribution of your content. Please start by visiting the website. If you have publishing questions and/or just want to talk about new publishing opportunities, please contact Jasna at (med.publishing@umich.edu). Health Sciences Publishing Services works in close collaboration with other units on campus, including Open.Michigan and the Taubman Health Sciences Library.

Machine Shop and Electronic Shop Services Available

The U-M Kresge Hearing Research Institute now offers the services of its senior mechanical and electronic design staff on a time-and-materials basis. Capabilities include mechanical and electronic instrument design, fabrication, and repair.

For more information, email (techshops@umich.edu) or contact:
Mechanical engineer – Dwayne Vailliencourt (734-764-6114)
Electrical engineer – Chris Ellinger (734-764-2311)

Annual Outside Interests, Activities, or Relationships Reports Required Using M-Inform
Reporting Begins: July 1, 2011 – Deadline: July 31, 2011

As in previous years, UMHS Policy 01-04-003 requires that all Medical School faculty members (instructional, clinical and research tracks) and House Officers report outside interests, activities, or relationships related to their work or position at UMHS that have the real or perceived potential to result in benefit to them or their spouses, domestic partners, or dependents.

  • “Related” means an interest, activity, or relationship that:
  • relies upon the clinical, research, teaching, or other expertise that the University considers part of your work at UMHS, or
  • has the potential to influence research, teaching, or provision of clinical care.
  • Examples include an equity interest or owning stock in a company; licensed intellectual property for which one could receive royalties; unpaid or paid consulting with a drug company.
  • Note: Gifts, salary, and other support from an outside entity (e.g., NIH, Pfizer) that are administered by DRDA or a University development office do not constitute an outside interest.

To comply with this UMHS Conflict of Interest policy, certain executives and management staff must also disclose their outside interests, activities, or relationships for themselves and their family members.

Key Points Include:

  • The Outside Interest Reporting Form (M-Inform) must be completed between July 1 and July 31.
  • Reporting forms will be reviewed between August 1 and August 31, with follow-up as needed.
  • Upon signing and submitting the form, MLearning will track one’s completion.
  • Reports and any additional information gathered shall be treated as sensitive data, and access to this information granted only to those University or UMHS personnel requiring such information to perform their duties.
  • The UMHS Conflict of Interest and Outside Interest Disclosures website is available to provide additional information on this process.

Access M-Inform at (http://www.umms.med.umich.edu/minform/). This electronic format provides an easy mechanism for submitting reports and allows participants to copy activities disclosed in previous years into their 2011 record as needed. Additional information can be found at (http://www.med.umich.edu/u/coi), and additional support is available by contacting (coi-oid-questions@med.umich.edu).

UM Researchers – Undergraduate Research Opportunity Program Seeks Research Partners in the Biomedical and Life Sciences for 2011-2012
Deadline: August 1, 2011

UROP Logo

Would you like help getting a new project started or expediting a project currently in progress? Do you have a project you put on hold because you need a research assistant to do some background research?   Would you like to introduce and recruit new students to your field?

We would like to invite you to join the Undergraduate Research Opportunity Program (UROP) as a research partner for bright and enthusiastic undergraduate students. We are now recruiting research partners for the 2011-2012 academic year.  If you are interested in involving a student in your research, scholarship, or creative activities, we encourage you to read more about the program and complete our online one-page application which can be found at the UROP website.

Our application asks you to provide a brief description of the overall project, (goals and objectives and methodology), what tasks you want the student to do, minimum qualifications, number of hours per week, and contact information for setting up interviews in the fall.

UROP Program Features

  1. UROP is open to first and second year students and, while they require training, many of our UROP students work on the same project throughout their academic careers at the University of Michigan making your training a long-term investment. In September, you will have the opportunity to interview and select the students you wish to invite into your project after reviewing a copy of the student’s resume.
  1. Students participate in the program the entire academic year from late September-May.
  1. UROP provides research skill building workshops including Matlab, Invivo, GIS, Endnote, SPSS, STATA, Refworks, Research Integrity and Responsibility, Advanced Excel, Animal Handling, Keeping a Laboratory Notebook, OSEH Safety, etc.
  1. Supplementary research funding of $500 per student is available to cover research related costs.
  1. UROP students participate in the program for academic credit or work-study support. If the student participates for work-study, UROP pays student wages, if applicable, and manages all paperwork.
  1. All UROP students are assigned a peer advisor who is a former UROP participant. Our peer advisors provide an important link between you and your student if problems arise and also help orient the student to faculty expectations for a research assistant.
  1. You provide 6-12 hours of work per week, supervise the student’s progress and assign a grade each term.
  1. Daily supervision can also be done by graduate students and other members of your research team along with contact with you either through research team meetings or other regularly scheduled meetings.
  1. UROP students can apply for summer research fellowships that enable the student to spend 10 weeks conducting part or full-time research.  Applications are due early February and require a student written proposal.

UROP can provide you with a UROP Sample Project Handout from your school or college to get you thinking about the ways in which a UROP student could participate in and assist you with your research.  Please contact Sandra Gregerman (sgreger@umich.edu) if you have questions about the program or would like to speak to a UROP research sponsor from your department. The application deadline is August 1, 2011, however we typically accept project applications until September 15.


SEMINARS + MAJOR EVENTS AND CONFERENCES

Please visit the calendar links on the right side menu to make sure you're "in the loop" with current events!


SHARPENING THE FOCUS:

Tips on Grant Proposal Preparation

Composing the NIH Cover Letter

by Christine Black,
Assistant Director for Research Services, Office of Research

The most important function of the cover letter is to make sure your (brilliant and carefully designed) work is reviewed (and appreciated) by the right group of scientists.  Here are some tips:

  • Address letter to the Center of Scientific Review (CSR) Division of Receipt and Referral (DRR)
  • Make sure you identify your name, University of Michigan, project title, and funding mechanism (PA or RFA)
  • In one line request specific study section, e.g. – MONC
  • See CSR Study Section Roster

  • In one line list the Institute(s) or Center you want  to consider proposal, e.g. – NCI

    You can check the NIH RePORTER to find similar projects along with which Institutes funded them, and which study sections reviewed them at (http://projectreporter.nih.gov/reporter.cfm)

  • Provide explanations for each special request in a separate paragraph, e.g.,
    • Identify Conflicts on the Roster, e.g., former student, co-author, direct competitor
    • List name and reason for conflict
  • Other issues (one paragraph each), e.g.,
    • State if you have attached any required agency approval documentation, e.g., those required for budgets of >$500,000
    • Special subawards
    • If your proposal is past the due date, explain why, e.g., your service on a study section.

If you have questions, please review guidelines in Section 5.2 of this online document.


EDUCATIONAL OPPORTUNITIES


Faculty Training Sessions on MBECT (Michigan Budget Enrollment Calendar Tool)

The purpose of these Faculty / PI Training Sessions is to provide UMHS Faculty with introductory training on how to use MBECT (formerly known as eThority). MBECT is a software tool for human clinical research which provides one point of data entry for building a research billing calendar, internal and sponsor budgets, in addition to subject enrollment.

We have two sessions available (please attend ONE session only):

Session One:
Tuesday, June 21, 2011
11:30 AM - 1:00 PM
UH (University Hospital) - B1C111

Session Two:
Monday, July 11, 2011
11:30 AM - 1:00 PM
MCHC Auditorium F2305

To register: Emailing (MBECT-help@umich.edu) – be sure to include the date you will attend – will serve as your confirmed registration. Boxed lunches will be provided.

Agenda:
11:30 - 11:40 AM – Opening remarks and boxed lunch
11:40 - 11:55 AM – Overview Power Point presentation
11:55 AM - 12: 35 PM – Demo of MBECT tool
12:35 - 12:50 PM – Questions and answers
12:50 - 1:00 PM – Closing remarks

Inserting Graphics into NIH Grant Applications

Thursday, June 23, 2011
10:00 AM - 12:00 PM
Taubman Learning Center, 2802 Medical Sciences Building II

Recent changes in the NIH grant application reduce the number of pages available for the research plan, making proper placement of images, charts and graphics critical. This session will cover basic features in Microsoft Word to help with grant application preparation, including image placement, captioning and wordwrap. Following a brief presentation, instructors will assist you with specific issues you're encountering in formatting your grant application – please feel free to bring sample documents! This workshop was developed in response to feedback from faculty members to both the Medical School Office of Research and the Health Sciences Libraries. Note: this session will be conducted using Word 2007 (docx), but we will briefly discuss other versions of Word. Sponsored by Taubman Health Sciences Library.

Register for this workshop.

Society for Ambulatory Assessment (SAA) 2011 Conference
“Assessing Real-World Impact of Clinical Interventions and Outcomes: The Science of Ambulatory Assessment”

Friday, June 24, 2011 and Saturday, June 25, 2011:  8:00 AM - 5:30 PM
Sunday, June 26, 2011:  8:00 AM - 1:00 PM
Biomedical Science Research Building (BSRB)

Technology now allows, with relative ease, the assessment of a variety of factors that affect health (e.g., physical activity, behaviors, emotional states, physiological parameters) in the home environment or other naturalistic contexts. This real-world capture of information has tremendous potential to enhance the impact of clinical rehabilitation strategies. During this 2½ day conference, researchers on ambulatory assessment of different disciplines will present their work and engage in a concentrated exchange of ideas during discussions and in separate break-out sessions. Sponsored by the National Institutes of Health; University of Michigan Department of Physical Medicine and Rehabilitation and Office of the Vice President for Research.

Visit the website to register and view more information.


FUNDING / AWARD OPPORTUNITIES

Abstracts listed here are general information about these funding programs. We strongly urge interested applicants to visit the listed website to verify complete eligibility, program information, and application procedures before submitting an application.

Follow this link to search for other funding and recognition opportunities. This webpage contains information on email alert groups, internal grant programs, upcoming limited submissions, and links to extramural funding search engines.


Internal Submissions

Michigan Diabetes Research and Training Center (MDRTC) Grant Program
Deadline: August 2, 2011 (5:00 PM)

Visit the website for complete information and application instructions. Applications must be prepared using the new application forms.  Contact Barbara Hawkins at 734-763-2561 or (hawkinsb@umich.edu) to obtain an application form.

  • Pilot/Feasibility Study Grant Program (MDRTC)

The purpose of the MDRTC Pilot/Feasibility Study Grant Program is to promote research on diabetes by new and established U-M faculty. The goal of this program is to enable investigators to generate a sufficient body of preliminary information for a successful application for major research funding from NIH or other national granting agencies. Grant proposals may be in the areas of basic biomedical research or in clinical, behavioral, epidemiological, health services or translational research. Proposals should address key questions in the pathogenesis, diagnosis, prevention or control of diabetes, its complications, or related endocrine or metabolic disorders (for example: counter-regulatory proteins, obesity, metabolic syndrome). Translational research projects should focus on the translation of research advances into clinical practice and include the identification of barriers to widespread adoption of new science and the testing of interventions to overcome these barriers. Individuals who have full-time instructional or research faculty positions at U-M are eligible to apply as Principal Investigators. Proposals are for one year of support with requested funding up to $50,000.

  • Diabetes Interdisciplinary Study Program (MDRTC/MCDC)

The Diabetes Interdisciplinary Studies Program (DISP) is jointly sponsored by the Michigan Diabetes Research and Training Center (MDRTC) and the Michigan Comprehensive Diabetes Center (MCDC).  This program promotes interdisciplinary collaboration between two U-M faculty members from distinct disciplines to focus their combined research strengths on cutting-edge areas in diabetes research. The intent is to foster synergistic collaboration between faculty members to advance scientific inquiry. Grant proposals may be in areas of basic biomedical research or in clinical, behavioral, epidemiological, health services or translational research. Proposals should address key questions in the pathogenesis, diagnosis, prevention or control of diabetes, its complications, or related endocrine or metabolic disorders (for example: counter-regulatory proteins, obesity, metabolic syndrome). The goal of this program is to enable investigators to generate a sufficient body of preliminary information for a successful application for major research funding from NIH or other national granting agencies. A minimum of two Co-Investigators are required as DISP applicants. Individuals who have full-time instructional, research or clinical track faculty positions at the U-M are eligible to apply as Co-Principal Investigators. Proposals are for one year of support with requested funding up to $100,000.

MICHR Pilot Grant Program in Clinical and Translational Research
Deadline: September 15, 2011

The Michigan Institute for Clinical & Health Research Pilot Grant Program (PGP) aims to facilitate and support innovative research across the translational spectrum and encourage interdisciplinary collaboration that promotes the development of transformative solutions for improving patient outcomes. The following mechanisms are offered in Round 11:

T1 – Bench to Bedside Collaborations (75K max.)

T1 – Endowment for Basic Sciences Partnership Accelerating Translation (50K max.)

T2 – Translational Science Award (50K max.)

T3 – Research Into Practice Networks (50K max.)

T3 – CURES: Community University Research Partnership (25K max.)

Proposals are sought from basic, clinical, and social scientists.  All UM clinical and research faculty are eligible to apply as Principal Investigators. Fellows in an ACGME accredited program are NOT eligible to apply; however, lecturer or instructor appointments, or higher are eligible.  Basic scientists are strongly encouraged to submit their application with a clinical scientist collaborator.

Visit the website for more details regarding descriptions of the grant mechanisms and application guidelines.  Please read the guidelines and requirements for each mechanism carefully as these may have changed.

A Letter of Intent is NOT required. Proposals will be submitted electronically through mGrants.

For questions, contact Debra Warrick, MICHR Pilot Program Coordinator at 734-998-7626 or (warrickd@umich.edu).


External Limited Submissions


These are opportunities in which the sponsor has limited the number of proposals allowed from an institution. These competitions require an internal review to select the proposals to submit to the sponsor from the University of Michigan.

The Hartwell Foundation Individual Biomedical Research Award
Internal Deadline: July 15, 2011
Foundation Deadline: November 1, 2011

The Hartwell Foundation Individual Biomedical Research Award provides support for three years at $100,000 direct cost per year.  The goal of the program is to support early-stage, innovative, and cutting-edge biomedical research that has not yet qualified for significant funding from outside sources and that should benefit children.  The Foundation in particular seems driven by leading edge science that has a “story” to it, and that the board member can “visualize.”  That means that there is a bit of bias toward somewhat applied research where one can visualize the (eventual) young patients.  The Foundation’s website offers profiles of much of its supported work including the names of researchers and the titles of their projects.  That may be useful to you as you consider this opportunity.

Michigan has received six of these awards in the last five years:  one each (with primary appointments) in Pharmacy (Victor Yang), Pharmacology (Asim Beg), BioMedical Engineering (Charles Cain), Pediatrics (Jamie Ferrara), Pediatric Surgery (Daniel Teitelbaum), and Dental School (Nan Hatch).  Please feel free to ask these scholars for feedback on ideas you may have for a Hartwell Foundation proposal.  The Hartwell Foundation hosts annual gatherings of its scholars and thus these scientists have exposure to the full complement of supported researchers.

Candidates should (1) be a citizen of the United States (2) hold a full-time appointment in the sponsoring institution (3) be eligible to serve as a principal investigator in biomedical research.  UM may nominate four candidates.

For consideration as an institutional nominee, submit the following electronically in a single PDF document to (feldkamp@umich.edu) by July 15, 2011:

  • 3-page research summary
  • NIH formatted biosketch
  • Nominating letter from the department chair

UM candidates selected to be nominated will be informed by early September.  A full proposal will be due to the Foundation by November 1, 2011.

A complete copy of The Hartwell Foundation's "Application Process and Administrative Guidelines" is available online.

Contact Julie Feldkamp (734-763-4522 or feldkamp@umich.edu), Maureen Martin (734-647-6074 or martinms@umich.edu) or Marvin Parnes (734-764-7231 or mgparnes@umich.edu) with any questions.

Searle and Pew Scholars Program Awards
Internal Deadline: Wednesday, August 3, 2011

Nominations of faculty from all units of the University are welcome for both the Searle Scholars Program and the Pew Scholars Program in the Biomedical Sciences. Only one nomination package is required for the internal selection of the University’s nominees for both programs. Faculty members who were nominated but not selected for the 2011 programs may apply for the 2012 programs if they continue to meet program eligibility requirements. Specific program information is noted below.

The internal nomination package must include:

  • Cover sheet (downloaded from the web link below)
  • A letter of nomination from the appropriate department chair or section head. This letter should indicate if the candidate is to be considered for the Searle and/or Pew Scholars Programs. Please also include the nominee's UM start date as an assistant professor (month/date/year).
  • A one to five page research statement including (1) current areas of research and (2) an overview of the specific areas of research the nominee would like to pursue with this funding award. Please also indicate the significance of this work and explain why it is particularly novel and important.
  • A current copy of the nominee's NIH formatted biosketch including a list of any current awards held by the nominee or awards they will have that overlap with the funding period of the Searle or Pew awards.
  • Any recent letters of support attesting to the potential of the nominee and the quality and scope of his/her research. These letters are for internal review; if they were obtained for another recent award review, please use those.

Please submit all application materials electronically by August 3, 2011 following the instructions listed on the cover sheet. Download the cover sheet.

We acknowledge receipt of all electronic submissions by the end of the next business day. If you do not receive a response from us, please call us at 734-615-8802.



Searle Scholars Program


(http://www.searlescholars.net)
Applicants for year 2012 awards will be expected to be pursuing independent research careers in biochemistry, cell biology, genetics, immunology, neuroscience, pharmacology, and related areas in chemistry, medicine, and the biological sciences. Candidates should have begun their first appointment at the assistant professor level on or after July 1, 2010 and therefore be in their first or second year in a tenure-track position. The awards are grants of $100,000 per year for three years, with funding for the second and third year contingent upon acceptable progress reports. The sponsor deadline is September 30, 2011. The University of Michigan is allowed to submit two nominations.



Pew Scholars Program in the Biomedical Sciences


(http://www.pewtrusts.org/our_work_category.aspx?id=194)
The Pew Scholars Program in the Biomedical Sciences is designed to support young investigators of outstanding promise in science relevant to the advancement of human health. The award is intended to provide support for junior faculty as they establish their laboratories. Candidates must hold a doctorate in medicine or biomedical sciences. As of November 1, 2011, candidates must hold full time appointments at the rank of assistant professor. On July 1, 2012, they must not have been in this appointment for more than three years. Scholars may not simultaneously be supported by similar private foundation awards in excess of $50,000 for the first two years of their Pew Scholarship. However, candidates who receive awards that support their salary only are eligible to apply. The award is $60,000 per year for four years subject to annual review of the Scholar’s progress. The sponsor’s deadline is November 1, 2011 (12:00 PM EDT). The University of Michigan is allowed to submit one nomination.

Contact Camille Mrozowski at 734-615-8802 or (cmrozow@umich.edu) with any questions about these programs.


UMMS AWARDED GRANTS

External Awarded Grants

An asterisk next to a name means that they are the Contact PI for the program, since some projects are awarded with multiple PIs.

Click here to view.

Anesthesiology

PI: *Blum,James
Title: Weaning and Variability Evaluation (WAVE)
Sponsor: Canadian Institute of Health Research (CIHR) TO Ottawa Health Research Institute
Project Dates and Amount of Award: 03/01/11-02/29/12; $11,368

PI: *Lydic,Ralph
Title: Student Anesthesia Research Fellowship
Sponsor: Foundation for Anesthesia Education and Research
Project Dates and Amount of Award: 06/01/11-12/31/11; $8,200

Biological Chemistry

PI: *Smith,William
Title: Assay Development for the Study of Regulated Gene Expression
Sponsor: Promega Corporation
Project Dates and Amount of Award: 11/01/10-10/31/11; $4,914

Dermatology

PI: *Fisher,Gary
Title: Therapeutic Implications of Immunologic Alterations in Rash Caused by EGFR Inhibitors
Sponsor: Dermatology Foundation
Project Dates and Amount of Award: 07/01/11-06/30/12; $20,000

PI: *Li,Yong
Title: Improving Appearance of Aged Skin by Limiting Intracellular Collagen Degradation
Sponsor: Dermatology Foundation
Project Dates and Amount of Award: 07/01/11-06/30/12; $55,000

Emergency Medicine

PI: *Younger,John
Title: Healthy Futures: Improving Health Outcomes for Young Children Curriculum for Managing Infectious Diseases in Early Education and Child Care Settings
Sponsor: American Academy of Pediatrics
Project Dates and Amount of Award: 03/22/11-04/30/12; $5,375

Family Medicine

PI: *Green,Lee
Title: University of Michigan and The Governors of the University Alberta Secondment Agreement
Sponsor: University of Alberta
Project Dates and Amount of Award: 05/01/11-06/30/12; $49,076

Human Genetics

PI: *Glover,Thomas
Title: Identifying Genes for Progeria and Premature Aging by Exome Sequencing
Sponsor: Progeria Research Foundation, Inc., The
Project Dates and Amount of Award: 05/01/11-04/30/12; $16,800

PI: *Rosenberg,Noah
Title: Collaborative Research: Novel Methodologies for Genome-Scale Evolutionary Analysis of Multi-Locus Data
Sponsor: NSF
Project Dates and Amount of Award: 07/01/11-06/30/14; $467,429

Internal Medicine

PI: *Arvan,Peter
Co-I: Liu, Ming (Metabolism, Endo & Diabetes)
Title: How Mutations in Proinsulin cause Neonatal Diabetes: a Protein-Misfolding Disease
Sponsor: NIH - Subcontracts TO Case Western Reserve Univ  R01 DK 069764
Project Dates and Amount of Award: 04/01/11-05/31/12; $61,977

PI: *Baptist,Alan
Title: A Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled Safety Study of Xolair (Omalizumab) in Patients with Chronic Idiopathic Urticaria (CIU) Who Remain Sympotmatic Despite Treatment with H1 Antihistamines, H2 Blockers and/or Leukotriene Receptor Antagonists
Sponsor: Genentech, Inc.
Project Dates and Amount of Award: 03/10/11-04/22/13; $163,550

PI: *Brook,Robert / Dvonch,Joseph / Mukherjee,Bhramar / Spino,Catherine
Co-I: Kaplan, Mariana (Int Med-Rheumatology) / Keeler, Gerald (Environmental Health Sciences) / Oral, Elif (Metabolism, Endo & Diabetes) / Sanchez Loya, Brisa (Biostatistics Department) / Wang, Lu (Biostatistics Department)
Title: Great Lakes Air Center for Integrative Environmental Research (GLACIER)
Sponsor: Environmental Protection Agency-Subcontracts TO Michigan State University
Project Dates and Amount of Award: 01/01/11-12/31/15; $1,543,442

PI: *Chun,Tae-Hwa
Title: CSCR's Early Career Development Award (ECDA)
Sponsor: Central Society for Clinical Research (CSCR)
Project Dates and Amount of Award: 01/01/11-12/31/11; $10,000

PI: *Eitzman,Daniel
Title: Determination of Thrombogenicity of the LepR Phe1077 Mouse
Sponsor: American Heart Association, Midwest Affiliate
Project Dates and Amount of Award: 06/01/11-08/31/11; $4,000

PI: *Halter,Jeffrey
Co-I: Lee, Pearl (Int Med-Geriatric Medicine) / Min, Lillian (Int Med-Geriatric Medicine) / Ruff, Tanya (Int Med-Geriatric Medicine) / Solomon, Gabriel (Int Med-General Medicine)
Title: Hartford Center of Excellence in Geriatrics
Sponsor: Hartford, John A. Foundation TO American Federation for Aging Research
Project Dates and Amount of Award: 07/01/11-06/30/12; $120,000

PI: *Higgins,Peter
Title: Protocol CCX114157, Entitled "A 52 week Randomised, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy and Safety of GSK1605786A in the Maintenance of Remission in Subjects with Crohn's Disease"
Sponsor: Glaxosmithkline TO Robarts Clinical Trials - Robarts Research Institute
Project Dates and Amount of Award: 06/01/11-05/31/13; $116,139

PI: *Hussain,Maha
Title: 2010.108:  A Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase II Trial Investigating Two Doses of EMD 525797 in Subjects with Asymptomatic or Mildly Symptomatic Metastatic Castrate-Resistant Prostate Cancer (mCRPC)
Sponsor: EMD Serono, Inc
Project Dates and Amount of Award: 05/05/11-05/31/13; $542,984

PI: *Hussain,Maha
Title: Millennium Prostate Cancer TAK700 C21006 Steering Committee Contract
Sponsor: Millennium Pharm, Inc.
Project Dates and Amount of Award: 04/12/11-04/01/13; $20,000

PI: *Hyzy,Robert
Title: A RANDOMIZED PHASE II TRIAL OF CMV PREVENTION IN ACUTE LUNG INJURY
Sponsor: NIH - Subcontracts TO Hutchinson, Fred, Cancer Research Center  U01 HL 102547
Project Dates and Amount of Award: 06/01/10-05/31/11; $38,653

PI: *Lama,Vibha
Title: Cellular and Biochemical Modulation of Inflammation and Fibrosis in Systemic Sclerosis
Sponsor: Scleroderma Foundation
Project Dates and Amount of Award: 05/01/11-04/30/12; $60,000

PI: *Peters-Golden,Marc
Title: Inhibition of Phagocyte Oxidase in Alveolar Macrophages by Prostaglandin E2
Sponsor: American Lung Association
Project Dates and Amount of Award: 07/01/11-06/30/12; $32,500

PI: *Peters-Golden,Marc / Martinez,Fernando
Co-I: Flaherty, Kevin (Int Med-Pulm./Critical Care) / Hogaboam, Cory (Pathology Department) / Huang, Steven (Int Med-Pulm./Critical Care) / Lama, Vibha (Int Med-Pulm./Critical Care) / Sisson, Thomas (Int Med-Pulm./Critical Care)
Title: Prostanoids, Plasminogen Activation, and Personalized Therapeutics in IPF
Sponsor: NIH  1 P50 HL 107177 01
Project Dates and Amount of Award: 05/01/11-04/30/13; $876,142

PI: *Redman,Bruce
Title: 2011.019:  A Randomized, Blinded, Phase 2 Dose-Ranging Study of BMS-936558 (MDX-1106) in Subjects With Progressive Advanced/Metastatic Clear-Cell Renal Cell Carcinoma Who Have Received Prior Anti-Angiogenic Therapy
Sponsor: Bristol-Myers Squibb
Project Dates and Amount of Award: 05/19/11-05/18/13; $153,951

PI: *Sood,Suman
Title: Risk Factors and Biomarkers for Venous Thrombosis in Acute Myelogenous Leukemia
Sponsor: American Society of Hematology
Project Dates and Amount of Award: 06/01/11-01/31/12; $4,000

PI: *Young,Vincent
Title: Immune System-Microbiota Interations and IBD
Sponsor: Centocor, Inc.
Project Dates and Amount of Award: 05/16/11-05/15/13; $171,990

Michigan Nanotechnology Institute for Medicine and Biological Sciences

PI: *Baker Jr,James
Co-I: Bielinska, Anna (MI Nanotechnology Institute) / Makidon, Paul (MI Nanotechnology Institute) / Myc, Andrzej (MI Nanotechnology Institute) / Smith, Douglas (MI Nanotechnology Institute) / Wang, Su (MI Nanotechnology Institute)
Title: RSV VACCINE
Sponsor: Gates, Bill and Melinda, Foundation TO NanoBio Corporation
Project Dates and Amount of Award: 12/01/10-11/30/12; $1,997,507

Microbiology and Immunology

PI: *King,Philip
Title: RASA1 as a Potential Therapeutic Target for Treatment of Lymphedema
Sponsor: American Heart Association, Midwest Affiliate
Project Dates and Amount of Award: 07/01/11-06/30/13; $95,224

Neurology

PI: *Morgenstern,Lewis
Title: A Community Partnership to Treat Stroke
Sponsor: NIH  1 K23 NS 073685 01
Project Dates and Amount of Award: 09/01/11-08/31/16; $866,700

PI: *Stacey,William
Title: Modeling Seizure Precursors and Antiepileptic Brain Stimulation
Sponsor: NIH  7 K08 NS 069783 01
Project Dates and Amount of Award: 07/01/11-06/30/16; $866,700

Neurosurgery

PI: *Fan,Xing
Title: The Notch Signaling Pathway in Glioblastoma
Sponsor: NIH  1 F32 NS 074744 01
Project Dates and Amount of Award: 09/01/11-08/31/13; $105,964

PI: *La Marca,Frank
Title: Neurosurgery Fellowship
Sponsor: Neurosurgery Research and Education Foundation (NREF)
Project Dates and Amount of Award: 07/01/11-06/30/12; $75,000

PI: *Muraszko,Karin
Title: American Association of Neurological Surgeons Fellowship-David Altshuler
Sponsor: American Association of Neurological Surgeons (AANS)
Project Dates and Amount of Award: 05/05/11-07/31/11; $2,500

PI: *Muraszko,Karin
Title: Characterization of Regional Expression in Recurrent High Grade Astroblastoma
Sponsor: American Brain Tumor Assoc
Project Dates and Amount of Award: 05/09/11-07/29/11; $3,000

Otolaryngology

PI: *Altschuler,Richard
Co-I: Dolan, David (Kresge Hearing Research Inst) / Miller, Josef (Otorhinolaryngology Department) / Shore, Susan (Kresge Hearing Research Inst)
Title: Prevention and Treatment of Noise-Induced Tinnitus
Sponsor: US DOD-Army, Department of the
Project Dates and Amount of Award: 07/01/11-07/31/14; $1,127,375

PI: *Schacht,Jochen
Title: Tuning Aminoglycosides for Treatment of Human Genetic Diseases
Sponsor: NIH - Subcontracts TO Technion - Israel Institute of Technology  R01 GM 094792
Project Dates and Amount of Award: 04/01/11-03/31/12; $93,440

Pathology

PI: *Chinnaiyan,Arul
Co-I: Maher, Christopher (Ctr fr Translational Pathology)
Title: Discovery of Novel Gene Elements Associated with Prostate Cancer Progression
Sponsor: US DOD-Army, Department of the
Project Dates and Amount of Award: 09/30/11-10/29/14; $699,736

PI: *Chinnaiyan,Arul
Title: High Throughput Next-Gen Sequencing to Investigate the Somatic Genetics of Prostate Cancer
Sponsor: US DOD-Army, Department of the
Project Dates and Amount of Award: 04/15/11-05/14/13; $122,529

PI: *Hogaboam,Cory
Title: Testing an Axikin Compound in a SCID Model of Idiopathic Pulmonary Fibrosis
Sponsor: Axikin Pharmaceuticals
Project Dates and Amount of Award: 06/01/11-06/30/12; $57,438

PI: *Lim,Megan
Title: Effectiveness of Tailored Activity Pacing for Symptomatic Osteoarthritis
Sponsor: Veterans Affairs, Dept. of
Project Dates and Amount of Award: 06/01/11-09/30/13; $9,609

PI: *Varani,James
Co-I: Bhagavathula, Narasimharao (Pathology Department) / Dame, Michael (Pathology Department)
Title: Dietary Trace Metals and Colon Cancer Prevention
Sponsor: Association for International Cancer Research (AICR)
Project Dates and Amount of Award: 06/01/11-05/31/13; $260,638

Pediatrics & Communicable Diseases

PI: *Gurney,James
Title: Predictors of Adolescent Sperm Banking: Development of a Profiling and Referral Tool Per Patient Reimbursement
Sponsor: NIH - Subcontracts TO St. Jude Children's Research Hospital  R21 HD 061296
Project Dates and Amount of Award: 07/15/10-06/30/11; $12,750

PI: *Hershenson,Marc
Co-I: Bentley, John (Pediatrics-Pulmonary Medicine)
Title: Mechanisms of Airway Smooth Muscle Hypertrophy
Sponsor: NIH  2 R01 HL 079339 06
Project Dates and Amount of Award: 07/01/11-06/30/16; $1,943,126

PI: *Hildebrandt,Friedhelm
Title: Mesonephric Model of Podocyte Injury and Regeneration
Sponsor: NIH  1 K99 DK 091405 01
Project Dates and Amount of Award: 06/01/11-05/31/13; $180,000

PI: *Lee,Joyce
Co-I: Kaciroti, Niko (Center for Human Growth & Dev) / Lumeng, Julie (Child Behavioral Health)
Title: Rate of Weight Gain, Linear Growth, and Development During Childhood
Sponsor: NIH  1 R03 HD 061438 01 A2
Project Dates and Amount of Award: 12/27/10-11/30/12; $167,786

PI: *Nasr,Samya
Co-I: Hassan, Fauziya (Pediatrics-Pulmonary Medicine)
Title: A Phase 3, Open-Label, Randomized Trial to Evaluate the Safety and Efficacy of MP-376 Inhalation Solution (Aeroquin) versus Tobramycin Inhalation Solution (TIS) in Stable Cystic Fibrosis Patients
Sponsor: Mpex Pharmaceuticals, Inc
Project Dates and Amount of Award: 05/06/11-05/31/13; $73,863

PI: *Shavit,Jordan
Title: Determinining Modifier Genes of PROC Deficiency
Sponsor: American Society of Hematology
Project Dates and Amount of Award: 06/01/11-09/01/11; $4,000

Pharmacology

PI: *Ko,Mei-Chuan
Title: Effects of NOP Receptor Agonists Following Spinal Administration in Monkeys
Sponsor: Purdue Pharma L.P.
Project Dates and Amount of Award: 03/03/11-04/12/12; $68,000

PI: *Martens,Jeffrey
Title: Therapeutic Rescue of an Olfactory Ciliopathy
Sponsor: NIH  1 F32 DC 011990 01
Project Dates and Amount of Award: 07/01/11-06/30/13; $99,724

Psychiatry

PI: *Giordani,Bruno
Title: Computerized Cognitive Rehabilitation in Ugandan Children After Severe Malaria
Sponsor: NIH - Subcontracts TO Michigan State University  R01 HD 064416
Project Dates and Amount of Award: 04/01/11-01/31/16; $149,241

Radiation Oncology

PI: *Sun,Yi
Co-I: Schipper, Matthew (Radiation Oncology - Ann Arbor)
Title: Mechanistic Validation of SCF E3 Ligase as a Cancer and Radiosensitizing Target
Sponsor: NIH  1 R01 CA 156744 01
Project Dates and Amount of Award: 05/11/11-03/31/16; $1,604,779

Radiology

PI: *Corbett,James
Co-I: Chetcuti, Stanley (Int Med-Cardiology)
Title: A Phase 3, Open-Label, Multicenter Study for the Assessment of Myocardial Perfusion using Positron Emission Tomography (PET) Imaging of Flurpiridaz F 18 Injection in Patients with Suspected or Known Coronary Artery Disease (CAD)
Sponsor: Lantheus Medical Imaging
Project Dates and Amount of Award: 05/11/11-05/10/13; $159,704

PI: *Dewaraja,Yuni
Co-I: Avram, Anca (Department of Radiology) / Fessler, Jeffrey (COE EECS - ECE Division) / Goodsitt, Mitchell (Department of Radiology) / Kaminski, Mark (Int Med-Hematology/Oncology) / Morgan, Meredith (Radiation Oncology - Ann Arbor) / Roberson, Peter (Radiation Oncology - Ann Arbor) / Schipper, Matthew (Radiation Oncology - Ann Arbor) / Smith, Lauren (Pathology Department) / Wilderman, Scott (Nuclear Eng & Radiological Sci)
Title: Imaging Based Dosimetry for Individualized Internal Emitter Therapy
Sponsor: NIH  2 R01 EB 001994 12
Project Dates and Amount of Award: 05/01/11-04/30/15; $1,953,817

Surgery

PI: *Eliason,Jonathan
Title: Treatment of Non-Compressible Torso Hemorrhage and Shock with a Novel Thoracic Aortic Balloon Occlusion System that is Rapidly Deployable and Fluoroscopy-Free
Sponsor: Defense, Department of-Air Force, Department of the
Project Dates and Amount of Award: 05/09/11-05/09/13; $899,902

PI: *Liu,Yang
Title: A Forward Genetic Screening for Prostate Cancer Progression Genes
Sponsor: US DOD-Army, Department of the
Project Dates and Amount of Award: 09/30/11-10/29/14; $583,125

PI: *Pagani,Francis
Title: Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) Renewal
Sponsor: NIH - Subcontracts TO University of Alabama at Birmingham (UAB)
Project Dates and Amount of Award: 12/01/10-11/30/11; $39,867

PI: *Simeone,Diane
Co-I: Pasca Di Magliano, Marina (General Surgery Section)
Title: The Effects of Compound 18R5 (anti-FZD) on PANIN Formation and Pancreatic Cancer
Sponsor: American Italian Cancer Foundation TO OncoMed Pharmaceuticals, Inc.
Project Dates and Amount of Award: 01/06/11-01/06/12; $104,978

Unit for Laboratory Animal Medicine

PI: *Dysko,Robert
Title: ULAM Services at NCRC
Sponsor: NIH - Subcontracts TO Phrixus Pharmaceuticals, Inc
Project Dates and Amount of Award: 04/20/11-04/19/12; $34,922

Urology

PI: *Keller,Evan
Title: Effects of Reparixin and Ladarixin on Bladder Cancer Stem Cells
Sponsor: Dompe Farmaceutici S.p.A.
Project Dates and Amount of Award: 04/01/11-03/31/12; $167,310

PI: *Macoska,Jill
Title: Chemokine Prostate Cancer Biomarkers
Sponsor: NIH - Subcontracts TO University of Texas  U01 CA 084986
Project Dates and Amount of Award: 07/01/10-09/30/11; $39,407


UMMS RESEARCH PUBLICATIONS

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Books – Chapters or Volumes of Books – Contributions to Books

Cell & Developmental Biology

Wu, William; Zhang, Helen H.; Welsh, Michael J., et al.  Gene Biotechnology, Third Edition.  Boca Raton: CRC Press, 2011.  575 p.

Psychiatry

Nesse RM, Jackson ED. Evolutionary foundations for psychiatric diagnosis: Making DSM-V valid  In: De Block A, Adriaens P, editors. Maladapting Minds: Philosophy, Psychiatry, and Evolutionary Theory. Oxford: Oxford University Press; 2011. p. 167-91.

Journal Articles

Anesthesiology

Green Carmen R. Being present: The role of narrative medicine in reducing the unequal burden of pain. Pain. 2011 May. 152(5): 965-6. PMID# 21310530

Mashour George A. Dreaming during anesthesia and sedation. Anesthesia and analgesia. 2011 May. 112(5): 1008-10. PMID# 21515647

Ramachandran Satya Krishna. Simple math or aberrant physiology: the complex question of modified metabolic syndrome. Anesthesiology. 2011 May. 114(5): 1252. PMID# 21521982

Green Carmen R, Hart-Johnson Tamera, Loeffler Deena R. Cancer-related chronic pain: examining quality of life in diverse cancer survivors. Cancer. 2011 May 1. 117(9): 1994-2003. PMID# 21509777

Nafiu Olubukola O, Burke Constance C, Chimbira Wilson T, Ackwerh Ray, Reynolds Paul I, Malviya Shobha. Prevalence of habitual snoring in children and occurrence of peri-operative adverse events. European journal of anaesthesiology. 2011 May. 28(5): 340-5. PMID# 21499199

Biological Chemistry

Kanki Tomotake, Klionsky Daniel J, Okamoto Koji. Mitochondria autophagy in yeast. Antioxidants&redox signaling. 2011 May 15. 14(10): 1989-2001. PMID# 21194379

Cedervall Peder E, Dey Mishtu, Li Xianghui, Sarangi Ritimukta, Hedman Britt, Ragsdale Stephen W, Wilmot Carrie M. Structural Analysis of a Ni-Methyl Species in Methyl-Coenzyme M Reductase from Methanothermobacter marburgensis. Journal of the American Chemical Society. 2011 Apr 20. 133(15): 5626-8. PMID# 21438550

Cao Stewart Siyan, Kaufman Randal J. iRhoms: ERADicating the Messenger in Growth Control Signaling. Developmental cell. 2011 Apr 19. 20(4): 414-6. PMID# 21497754

Sanishvili Ruslan, Yoder Derek W, Pothineni Sudhir Babu, Rosenbaum Gerd, Xu Shenglan, Vogt Stefan, Stepanov Sergey, Makarov Oleg A, Corcoran Stephen, Benn Richard, Nagarajan Venugopalan, Smith Janet L, Fischetti Robert F. Radiation damage in protein crystals is reduced with a micron-sized X-ray beam. Proceedings of the National Academy of Sciences of the United States of America. 2011 Apr 12. 108(15): 6127-32. PMID# 21444772

Cell & Developmental Biology

Hosoya-Ohmura Sakie, Lin Yu-Hsuan, Herrmann Mary, Kuroha Takashi, Rao Arvind, Moriguchi Takashi, Lim Kim-Chew, Hosoya Tomonori, Engel James Douglas. An NK and T cell enhancer lies 280 kilobase pairs 3' to the gata3 structural gene. Molecular and cellular biology. 2011 May. 31(9): 1894-904. PMID# 21383068

Center for Computational Medicine and Bioinformatics

Senthamaraikannan Paranthaman, Sartor Maureen A, O'Connor Kyle T, Neumann Jonathan C, Klyza James P, Succop Paul A, Wagner Brad D, Karyala Saikumar, Medvedovic Mario, Menon Anil G. Identification of maternally regulated fetal gene networks in the placenta with a novel embryo transfer system in mice. Physiological genomics. 2011 Apr 12. 43(7): 317-24. PMID# 21205871

Dermatology

Shuman Andrew G, Light Emily, Olsen Stephen H, Pynnonen Melissa A, Taylor Jeremy M G, Johnson Timothy M, Bradford Carol R. Mucosal melanoma of the head and neck: predictors of prognosis. Archives of otolaryngology--head&neck surgery. 2011 Apr. 137(4): 331-7. PMID# 21502471

Wong Sandra L, Sabel Michael S, Johnson Timothy M. Sentinel lymph node biopsy for melanoma: one procedure but many questions: comment on "prognostic usefulness of sentinel lymph node biopsy for patients who have clinically node negative, localized, primary invasive cutaneous melanoma". Archives of dermatology. 2011 Apr. 147(4): 415-6. PMID# 21482891

Rittié Laure, Perbal Bernard, Castellot John J, Orringer Jeffrey S, Voorhees John J, Fisher Gary J. Spatial-temporal modulation of CCN proteins during wound healing in human skin in vivo. Journal of cell communication and signaling. 2011 Mar. 5(1): 69-80. PMID# 21484592

Emergency Medicine

El-Sayed A M, Scarborough P, Galea S. Ethnic inequalities in obesity among children and adults in the UK: a systematic review of the literature. Obesity reviews : an official journal of the International Association for the Study of Obesity. 2011 May. 12(5): e516-34. PMID# 21348920

Family Medicine

Adhikari Amita, Sen Ananda, Brumbaugh Robert C, Schwartz Jessica. Altered growth patterns of a mountain Ok population of Papua New Guinea over 25 years of change. American journal of human biology : the official journal of the Human Biology Council. 2011 May. 23(3): 325-32. PMID# 21484912

Khodaee Morteza, Fetters Michael D, Gorenflo Daniel W. Football (soccer) safety equipment use and parental attitudes toward safety equipment in a community youth sports program. Research in sports medicine (Print). 2011 Apr. 19(2): 129-43. PMID# 21480059

Human Genetics

Kalantry Sundeep. Recent advances in X-chromosome inactivation. Journal of cellular physiology. 2011 Jul. 226(7): 1714-8. PMID# 21344379

Williams Lucy H, Kalantry Sundeep, Starmer Joshua, Magnuson Terry. Transcription precedes loss of Xist coating and depletion of H3K27me3 during X-chromosome reprogramming in the mouse inner cell mass. Development (Cambridge, England). 2011 May. 138(10): 2049-57. PMID# 21471155

Katona Istvan, Zhang Xuebao, Bai Yunhong, Shy Michael E, Guo Jiasong, Yan Qing, Hatfield James, Kupsky William J, Li Jun. Distinct pathogenic processes between Fig4-deficient motor and sensory neurons. The European journal of neuroscience. 2011 Apr. 33(8): 1401-10. PMID# 21410794

Internal Medicine – Allergy and Clinical Immunology

Mullen Douglas G, McNerny Daniel Q, Desai Ankur, Cheng Xue-Min, Dimaggio Stassi C, Kotlyar Alina, Zhong Yueyang, Qin Suyang, Kelly Christopher V, Thomas Thommey P, Majoros Istvan, Orr Bradford G, Baker James R, Banaszak Holl Mark M. Design, synthesis, and biological functionality of a dendrimer-based modular drug delivery platform. Bioconjugate chemistry. 2011 Apr 20. 22(4): 679-89. PMID# 21425790

Zhang Yuehua, Thomas Thommey P, Lee Kyung-Hoon, Li Minghsin, Zong Hong, Desai Ankur M, Kotlyar Alina, Huang Baohua, Banaszak Holl Mark M, Baker James R. Polyvalent saccharide-functionalized generation 3 poly(amidoamine) dendrimer-methotrexate conjugate as a potential anticancer agent. Bioorganic&medicinal chemistry. 2011 Apr 15. 19(8): 2557-64. PMID# 21459000

Internal Medicine – Cardiovascular Medicine

Brook Robert D, Brook Jeffrey R. A road forward to improve public health. Circulation. 2011 Apr 26. 123(16): 1705-8. PMID# 21482961

Reed Michael C, Dhaliwal Gurpreet, Saint Sanjay, Nallamothu Brahmajee K. Clinical problem-solving. The right angle. The New England journal of medicine. 2011 Apr 7. 364(14): 1350-6. PMID# 21470013

Share David A, Campbell Darrell A, Birkmeyer Nancy, Prager Richard L, Gurm Hitinder S, Moscucci Mauro, Udow-Phillips Marianne, Birkmeyer John D. How a regional collaborative of hospitals and physicians in michigan cut costs and improved the quality of care. Health affairs (Project Hope). 2011 Apr. 30(4): 636-45. PMID# 21471484

Gakenheimer Lindsey, Lange Dave C, Romero Joshua, Kirkpatrick James N, Sovitch Patricia, Oral Hakan, Eagle Kim A, Baman Timir S. Societal views of pacemaker reutilization for those with untreated symptomatic bradycardia in underserved nations. Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing. 2011 Apr. 30(3): 261-6. PMID# 21249438

Latchamsetty Rakesh, Morady Fred. Complex fractionated atrial electrograms: a worthwhile target for ablation of atrial fibrillation? Circulation. Arrhythmia and electrophysiology. 2011 Apr 1. 4(2): 117-8. PMID# 21505172

Internal Medicine – Gastroenterology

Volk M L, Reichert H A, Lok A S F, Hayward R A. Variation in Organ Quality between Liver Transplant Centers. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2011 May. 11(5): 958-64. PMID# 21466651

Carethers John M, Goel Ajay. Our new president-C. Richard boland, MD. Gastroenterology. 2011 May. 140(5): 1675-9. PMID# 21443882

Tack Jan, Carethers John M. This month in gastroenterology. Gastroenterology. 2011 May. 140(5): 1365-8. PMID# 21440583

Jorgensen Jennifer E, Waljee Akbar K, Volk Michael L, Sonnenday Christopher J, Elta Grace H, Al-Hawary Mahmoud M, Singal Amit G, Taylor Jason R, Elmunzer B Joseph. Is MRCP equivalent to ERCP for diagnosing biliary obstruction in orthotopic liver transplant recipients? A meta-analysis. Gastrointestinal endoscopy. 2011 May. 73(5): 955-62. PMID# 21316670

Scheiman James M, Devereaux P J, Herlitz Johan, Katelaris Peter H, Lanas Angel, Veldhuyzen van Zanten Sander, Nauclér Emma, Svedberg Lars-Erik. Prevention of peptic ulcers with esomeprazole in patients at risk of ulcer development treated with low-dose acetylsalicylic acid: a randomised, controlled trial (OBERON). Heart (British Cardiac Society). 2011 May. 97(10): 797-802. PMID# 21415072

Al-Hawary Mahmoud M, Zimmermann Ellen M. Choosing the right cross-sectional imaging technique: Trading image quality for radiation risk. Inflammatory bowel diseases. 2011 May. 17(5): 1089-91. PMID# 21484960

Ramcharran D, Wahed A S, Conjeevaram H S, Evans R W, Wang T, Belle S H, Yee L J. Serum lipids and their associations with viral levels and liver disease severity in a treatment-naïve chronic hepatitis C type 1-infected cohort. Journal of viral hepatitis. 2011 Apr. 18(4): e144-52. PMID# 21070504

Internal Medicine – General Medicine

Janz Nancy K, Hawley Sarah T, Mujahid Mahasin S, Griggs Jennifer J, Alderman Amy, Hamilton Ann S, Graff John J, Jagsi Reshma, Katz Steven J. Correlates of worry about recurrence in a multiethnic population-based sample of women with breast cancer. Cancer. 2011 May 1. 117(9): 1827-36. PMID# 21445916

Volk M L, Reichert H A, Lok A S F, Hayward R A. Variation in Organ Quality between Liver Transplant Centers. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2011 May. 11(5): 958-64. PMID# 21466651

Reed Michael C, Dhaliwal Gurpreet, Saint Sanjay, Nallamothu Brahmajee K. Clinical problem-solving. The right angle. The New England journal of medicine. 2011 Apr 7. 364(14): 1350-6. PMID# 21470013

Fisher Gwenith G, Franks Melissa M, Plassman Brenda L, Brown Stephanie L, Potter Guy G, Llewellyn David, Rogers Mary A M, Langa Kenneth M. Caring for individuals with dementia and cognitive impairment, not dementia: findings from the aging, demographics, and memory study. Journal of the American Geriatrics Society. 2011 Mar. 59(3): 488-94. PMID# 21391939

Internal Medicine – Hematology and Oncology

Sun Xueqing, Cheng Guangcun, Hao Mingang, Zheng Jianghua, Zhou Xiaoming, Zhang Jian, Taichman Russell S, Pienta Kenneth J, Wang Jianhua. Erratum to: CXCL12 / CXCR4 / CXCR7 chemokine axis and cancer progression. Cancer metastasis reviews. 2011 Jun. 30(2): 269-70. PMID# 21072678

Hosing Chitra, Nash Richard, McSweeney Peter, Mineishi Shin, Seibold James, Griffith Linda M, Shulman Howard, Goldmuntz Ellen, Mayes Maureen, Parikh Chirag R, Crofford Leslie, Keyes-Elstein Lynette, Furst Daniel, Steen Virginia, Sullivan Keith M. Acute kidney injury in patients with systemic sclerosis participating in hematopoietic cell transplantation trials in the United States. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 2011 May. 17(5): 674-81. PMID# 20708086

Janz Nancy K, Hawley Sarah T, Mujahid Mahasin S, Griggs Jennifer J, Alderman Amy, Hamilton Ann S, Graff John J, Jagsi Reshma, Katz Steven J. Correlates of worry about recurrence in a multiethnic population-based sample of women with breast cancer. Cancer. 2011 May 1. 117(9): 1827-36. PMID# 21445916

Cai Qian, Sun Haiying, Peng Yuefeng, Lu Jianfeng, Nikolovska-Coleska Zaneta, McEachern Donna, Liu Liu, Qiu Su, Yang Chao-Yie, Miller Rebecca, Yi Han, Zhang Tao, Sun Duxin, Kang Sanmao, Guo Ming, Leopold Lance, Yang Dajun, Wang Shaomeng. A Potent and Orally Active Antagonist (SM-406/AT-406) of Multiple Inhibitor of Apoptosis Proteins (IAPs) in Clinical Development for Cancer Treatment. Journal of medicinal chemistry. 2011 Apr 28. 54(8): 2714-26. PMID# 21443232

Moore Helen M, Kelly Andrea B, Jewell Scott D, McShane Lisa M, Clark Douglas P, Greenspan Renata, Hayes Daniel F, Hainaut Pierre, Kim Paula, Mansfield Elizabeth A, Potapova Olga, Riegman Peter, Rubinstein Yaffa, Seijo Edward, Somiari Stella, Watson Peter, Biospecimen reporting for improved study quality (BRISQ). Cancer cytopathology. 2011 Apr 25. 119(2): 92-102. PMID# 21433001

Wicha Max S, Hayes Daniel F. Circulating tumor cells: not all detected cells are bad and not all bad cells are detected. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2011 Apr 20. 29(12): 1508-11. PMID# 21422428

Shiozawa Yusuke, Pedersen Elisabeth A, Havens Aaron M, Jung Younghun, Mishra Anjali, Joseph Jeena, Kim Jin Koo, Patel Lalit R, Ying Chi, Ziegler Anne M, Pienta Michael J, Song Junhui, Wang Jingcheng, Loberg Robert D, Krebsbach Paul H, Pienta Kenneth J, Ta Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow. The Journal of clinical investigation. 2011 Apr 1. 121(4): 1298-312. PMID# 21436587

Yang Jie, McEachern Donna, Li Wenyan, Davis Mary A, Li Hua, Morgan Meredith A, Bai Longchuan, Sebolt Jonathan T, Sun Haiying, Lawrence Theodore S, Wang Shaomeng, Sun Yi. Radiosensitization of Head and Neck Squamous Cell Carcinoma by a SMAC-Mimetic Compound, SM-164, Requires Activation of Caspases. Molecular cancer therapeutics. 2011 Apr. 10(4): 658-69. PMID# 21282353

Filson Christopher P, Redman Bruce G, Dunn Rodney L, Miller David C. Initial patterns of care with oral targeted therapies for patients with renal cell carcinoma. Urology. 2011 Apr. 77(4): 825-830.e1. PMID# 21256539

Kalemkerian Gregory P. Advances in the treatment of small-cell lung cancer. Seminars in respiratory and critical care medicine. 2011 Feb. 32(1): 94-101. PMID# 21500128

Internal Medicine – Infectious Diseases

Kauffman Carol A, Fisher John F, Sobel Jack D, Newman Cheryl A. Candida urinary tract infections--diagnosis. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2011 May. 52 Suppl 6(): S452-6. PMID# 21498838

Sobel Jack D, Fisher John F, Kauffman Carol A, Newman Cheryl A. Candida urinary tract infections--epidemiology. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2011 May. 52 Suppl 6(): S433-6. PMID# 21498836

Kaul D R, Stoelben S, Cober E, Ojo T, Sandusky E, Lischka P, Zimmermann H, Rubsamen-Schaeff H. First Report of Successful Treatment of Multidrug-Resistant Cytomegalovirus Disease with the Novel Anti-CMV Compound AIC246. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2011 May. 11(5): 1079-84. PMID# 21521474

Nichani Satyen, Cinti Sandro, Barsuk Jeffrey H. "Making a list and checking it twice". Journal of hospital medicine : an official publication of the Society of Hospital Medicine. 2011 Apr. 6(4): 165-9. PMID# 21480497

Hage Chadi A, Kirsch Emily J, Stump Timothy E, Kauffman Carol A, Goldman Mitchell, Connolly Patricia, Johnson Philip C, Wheat L Joseph, Baddley John W. Histoplasma Antigen Clearance during Treatment of Histoplasmosis in Patients with AIDS Determined by a Quantitative Antigen Enzyme Immunoassay. Clinical and vaccine immunology : CVI. 2011 Apr. 18(4): 661-6. PMID# 21307278

Internal Medicine – Metabolism, Endocrinology & Diabetes

Glynos Emmanouil, Frieberg Bradley, Oh Hyunjoon, Liu Ming, Gidley David W, Green Peter F. Role of molecular architecture on the vitrification of polymer thin films. Physical review letters. 2011 Mar 25. 106(12): 128301. PMID# 21517356

Internal Medicine – Molecular Medicine & Genetics

Ma Teng, Keller Jennifer A, Yu Xiaochun. RNF8-dependent histone ubiquitination during DNA damage response and spermatogenesis. Acta biochimica et biophysica Sinica. 2011 May. 43(5): 339-45. PMID# 21444325

Wellik Deneen, Sun Xin, Boekhoff-Falk Grace. John F. Fallon, PhD: Fifty years of excellence in limb research and counting. Developmental dynamics : an official publication of the American Association of Anatomists. 2011 May. 240(5): 909-14. PMID# 21400634

Valle L, Capellá G, Moreno V R, Rennert G, Gruber S B. Reply: Allelic imbalance of TGFBR1 is not a major contributor to the genetic predisposition to colorectal cancer. British journal of cancer. 2011 Apr 26. 104(9): 1519-20. PMID# 21522153

Samadder N Jewel, Mukherjee Bhramar, Huang Shu-Chen, Ahn Jaeil, Rennert Hedy S, Greenson Joel K, Rennert Gad, Gruber Stephen B. Risk of colorectal cancer in self-reported inflammatory bowel disease and modification of risk by statin and NSAID use. Cancer. 2011 Apr 15. 117(8): 1640-8. PMID# 21472711

Omenn Gilbert S. An omics perspective on cancer research. Expert review of proteomics. 2011 Apr. 8(2): 147-8. PMID# 21501006

Internal Medicine – Nephrology

Zhu Yunxiang, Gumlaw Nathan, Karman Jozsef, Zhao Hongmei, Zhang Jinhua, Jiang Ji-Lei, Maniatis Pete, Edling Andrea, Chuang Wei-Lien, Siegel Craig, Shayman James A, Kaplan Johanne, Jiang Canwen, Cheng Seng H. Lowering Glycosphingolipid Levels in CD4+ T Cells Attenuates T Cell Receptor Signaling, Cytokine Production, and Differentiation to the Th17 Lineage. The Journal of biological chemistry. 2011 Apr 29. 286(17): 14787-94. PMID# 21402703

Leichtman Alan B, McCullough Keith P, Wolfe Robert A. Improving the allocation system for deceased-donor kidneys. The New England journal of medicine. 2011 Apr 7. 364(14): 1287-9. PMID# 21410390

Internal Medicine – Pulmonary and Critical Care

Higgins M, Galvin D, McAuliffe F, Coffey M, Firth R, Daly S, Coleman E, Kinsley B, Geary M, Byrne M, Coulter-Smyth S, Foley M. Pregnancy in women with Type 1 and Type 2 diabetes in Dublin. Irish journal of medical science. 2011 Jun. 180(2): 469-73. PMID# 21312001

Reka Ajaya Kumar, Goswami Moloy T, Krishnapuram Rashmi, Standiford Theodore J, Keshamouni Venkateshwar G. Molecular cross-regulation between PPAR-¿ and other signaling pathways: Implications for lung cancer therapy. Lung cancer (Amsterdam, Netherlands). 2011 May. 72(2): 154-9. PMID# 21354647

Arora Shikha, Olszewski Michal A, Tsang Tiffany M, McDonald Roderick A, Toews Galen B, Huffnagle Gary B. Effect of Cytokine Interplay on Macrophage Polarization during Chronic Pulmonary Infection with Cryptococcus neoformans. Infection and immunity. 2011 May. 79(5): 1915-26. PMID# 21383052

Badri Linda, Murray Susan, Liu Lyrica X, Walker Natalie M, Flint Andrew, Wadhwa Anish, Chan Kevin M, Toews Galen B, Pinsky David J, Martinez Fernando J, Lama Vibha N. Mesenchymal stromal cells in bronchoalveolar lavage as predictors of bronchiolitis obliterans syndrome. American journal of respiratory and critical care medicine. 2011 Apr 15. 183(8): 1062-70. PMID# 21169468

Arenberg Douglas. Bronchioloalveolar carcinoma. Seminars in respiratory and critical care medicine. 2011 Feb. 32(1): 52-61. PMID# 21500124

Michigan Nanotechnology Institute for Medicine and Biological Sciences

Mullen Douglas G, McNerny Daniel Q, Desai Ankur, Cheng Xue-Min, Dimaggio Stassi C, Kotlyar Alina, Zhong Yueyang, Qin Suyang, Kelly Christopher V, Thomas Thommey P, Majoros Istvan, Orr Bradford G, Baker James R, Banaszak Holl Mark M. Design, synthesis, and biological functionality of a dendrimer-based modular drug delivery platform. Bioconjugate chemistry. 2011 Apr 20. 22(4): 679-89. PMID# 21425790

Zhang Yuehua, Thomas Thommey P, Lee Kyung-Hoon, Li Minghsin, Zong Hong, Desai Ankur M, Kotlyar Alina, Huang Baohua, Banaszak Holl Mark M, Baker James R. Polyvalent saccharide-functionalized generation 3 poly(amidoamine) dendrimer-methotrexate conjugate as a potential anticancer agent. Bioorganic&medicinal chemistry. 2011 Apr 15. 19(8): 2557-64. PMID# 21459000

Microbiology and Immunology

Strozen Timothy G, Stanley Heather, Gu Yuqi, Boyd Jessica, Bagdasarian Michael, Sandkvist Maria, Howard S Peter. Involvement of the GspAB Complex in Assembly of the Type II Secretion System Secretin of Aeromonas and Vibrio Species. Journal of bacteriology. 2011 May. 193(9): 2322-31. PMID# 21378198

Swulius Matthew T, Chen Songye, Jane Ding H, Li Zhuo, Briegel Ariane, Pilhofer Martin, Tocheva Elitza I, Lybarger Suzanne R, Johnson Tanya L, Sandkvist Maria, Jensen Grant J. Long helical filaments are not seen encircling cells in electron cryotomograms of rod-shaped bacteria. Biochemical and biophysical research communications. 2011 Apr 22. 407(4): 650-5. PMID# 21419100

Molecular & Integrative Physiology

Maures Travis J, Su Hsiao-Wen, Argetsinger Lawrence S, Grinstein Sergio, Carter-Su Christin. Phosphorylation controls a dual-function polybasic nuclear localization sequence in the adapter protein SH2B1{beta} to regulate its cellular function and distribution. Journal of cell science. 2011 May 1. 124(Pt 9): 1542-52. PMID# 21486950

Low Malcolm J. Agnostic about in Vivo Inverse Agonism of Agouti-Related Peptide. Endocrinology. 2011 May. 152(5): 1731-3. PMID# 21511984

Adhikari Amita, Sen Ananda, Brumbaugh Robert C, Schwartz Jessica. Altered growth patterns of a mountain Ok population of Papua New Guinea over 25 years of change. American journal of human biology : the official journal of the Human Biology Council. 2011 May. 23(3): 325-32. PMID# 21484912

Williams Antionette L, Bielopolski Noa, Meroz Daphna, Lam Alice D, Passmore Daniel R, Ben-Tal Nir, Ernst Stephen A, Ashery Uri, Stuenkel Edward L. Structural and functional analysis of tomosyn identifies domains important in exocytotic regulation. The Journal of biological chemistry. 2011 Apr 22. 286(16): 14542-53. PMID# 21330375

Sandefur Conner I, Schnell Santiago. A model of threshold behavior reveals rescue mechanisms of bystander proteins in conformational diseases. Biophysical journal. 2011 Apr 20. 100(8): 1864-73. PMID# 21504722

Adams Gregory N, Larusch Gretchen A, Stavrou Evi, Zhou Yihua, Nieman Marvin T, Jacobs Gretta H, Cui Yingjie, Lu Yuan, Jain Mukesh K, Mahdi Fakhri, Shariat-Madar Zia, Okada Yoshio, D'Alecy Louis G, Schmaier Alvin H. Murine prolylcarboxypeptidase depletion induces vascular dysfunction with hypertension and faster arterial thrombosis. Blood. 2011 Apr 7. 117(14): 3929-37. PMID# 21297000

Weerasinghe Sujith V W, Moons David S, Altshuler Peter J, Shah Yatrik M, Omary M Bishr. Fibrinogen-¿ proteolysis and solubility dynamics during apoptotic mouse liver injury: heparin prevents and treats liver damage. Hepatology (Baltimore, Md.). 2011 Apr. 53(4): 1323-32. PMID# 21480334

Ramaswamy Krishnan S, Palmer Mark L, van der Meulen Jack H, Renoux Abigail, Kostrominova Tatiana Y, Michele Daniel E, Faulkner John A. Lateral transmission of force is impaired in skeletal muscles of dystrophic mice and very old rats. The Journal of physiology. 2011 Mar 1. 589(Pt 5): 1195-208. PMID# 21224224

Neurology

Kim Bhumsoo, Sullivan Kelli A, Backus Carey, Feldman Eva L. Cortical neurons develop insulin resistance and blunted akt signaling: a potential mechanism contributing to enhanced ischemic injury in diabetes. Antioxidants&redox signaling. 2011 May 15. 14(10): 1829-39. PMID# 21194385

Gruis Kirsten L, Wren Patricia A, Huggins Jane E. Amyotrophic lateral sclerosis patients' self-reported satisfaction with assistive technology. Muscle&nerve. 2011 May. 43(5): 643-7. PMID# 21462207

Kutcher Jeffrey S, Giza Christopher C. Sideline assessment of sports concussion: The lure of simplicity. Neurology. 2011 Apr 26. 76(17): 1450-1. PMID# 21451153

Hassan Fauziya, Davis Matthew M, Chervin Ronald D. No Independent Association between Insufficient Sleep and Childhood Obesity in the National Survey of Children's Health. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. 2011 Apr 15. 7(2): 153-7. PMID# 21509329

Meng He, Chen Guoan, Zhang Xiaojie, Wang Zhuwen, Thomas Dafydd G, Giordano Thomas J, Beer David G, Wang Michael M. Stromal LRP1 in Lung Adenocarcinoma Predicts Clinical Outcome. Clinical cancer research : an official journal of the American Association for Cancer Research. 2011 Apr 15. 17(8): 2426-33. PMID# 21325077

Neurosurgery

Shah H, Gemmete J J, Chaudhary N, Pandey A S, Ansari S A. Acute life-threatening hemorrhage in patients with head and neck cancer presenting with carotid blowout syndrome: follow-up results after initial hemostasis with covered-stent placement. AJNR. American journal of neuroradiology. 2011 Apr. 32(4): 743-7. PMID# 21436338

Obstetrics & Gynecology

Sowers Maryfran R, Randolph John F, Zheng Huiyong, Jannausch Mary, McConnell Daniel, Kardia Sharon R, Crandall Carolyn J, Nan Bin. Genetic polymorphisms and obesity influence estradiol decline during the menopause. Clinical endocrinology. 2011 May. 74(5): 618-23. PMID# 21198743

Ophthalmology & Visual Sciences

Chavali Venkata R M, Khan Naheed W, Cukras Catherine A, Bartsch Dirk-Uwe, Jablonski Monica M, Ayyagari Radha. A CTRP5 gene S163R mutation knock-in mouse model for late-onset retinal degeneration. Human molecular genetics. 2011 May 15. 20(10): 2000-14. PMID# 21349921

Zhang Fuxiang, Sugar Alan, Jacobsen Gordon, Collins Melissa. Visual function and spectacle independence after cataract surgery: Bilateral diffractive multifocal intraocular lenses versus monovision pseudophakia. Journal of cataract and refractive surgery. 2011 May. 37(5): 853-8. PMID# 21511153

Collin Rob W J, van den Born L Ingeborgh, Klevering B Jeroen, de Castro-Miró Marta, Littink Karin W, Arimadyo Kentar, Azam Maleeha, Yazar Volkan, Zonneveld Marijke N, Paun Codrut C, Siemiatkowska Anna M, Strom Tim M, Hehir-Kwa Jayne Y, Kroes Hester Y, de High-resolution homozygosity mapping is a powerful tool to detect novel mutations causative of autosomal recessive RP in the Dutch population. Investigative ophthalmology&visual science. 2011 Apr. 52(5): 2227-39. PMID# 21217109

Shtein Roni M, Newton Duane W, Elner Victor M. Actinomyces infectious crystalline keratopathy. Archives of ophthalmology. 2011 Apr. 129(4): 515-7. PMID# 21482881

Kish Phillip E, Bohnsack Brenda L, Gallina Donika, Kasprick Daniel S, Kahana Alon. The eye as an organizer of craniofacial development. Genesis (New York, N.Y. : 2000). 2011 Apr. 49(4): 222-30. PMID# 21309065

Orthopaedic Surgery

Fox Alice J S, Bedi Asheesh, Deng Xiang-Hua, Ying Liang, Harris Paul E, Warren Russell F, Rodeo Scott A. Diabetes mellitus alters the mechanical properties of the native tendon in an experimental rat model. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2011 Jun. 29(6): 880-5. PMID# 21246619

Otolaryngology

Kondo Takako, Matsuoka Akihiro J, Shimomura Atsushi, Koehler Karl R, Chan Rebecca J, Miller Josef M, Srour Edward F, Hashino Eri. Wnt signaling promotes neuronal differentiation from mesenchymal stem cells through activation of tlx3. Stem cells (Dayton, Ohio). 2011 May. 29(5): 836-46. PMID# 21374761

Shuman Andrew G, Light Emily, Olsen Stephen H, Pynnonen Melissa A, Taylor Jeremy M G, Johnson Timothy M, Bradford Carol R. Mucosal melanoma of the head and neck: predictors of prognosis. Archives of otolaryngology--head&neck surgery. 2011 Apr. 137(4): 331-7. PMID# 21502471

Pathology

Banerjee Rajat, Henson Bradley S, Russo Nickole, Tsodikov Alex, D'Silva Nisha J. Rap1 mediates galanin receptor 2-induced proliferation and survival in squamous cell carcinoma. Cellular signalling. 2011 Jul. 23(7): 1110-8. PMID# 21345369

Varani J. Calcium, calcium-sensing receptor and growth control in the colonic mucosa. Histology and histopathology. 2011 Jun. 26(6): 769-79. PMID# 21472691

Evans Christopher G, Smith Matthew C, Carolan James P, Gestwicki Jason E. Improved synthesis of 15-deoxyspergualin analogs using the Ugi multi-component reaction. Bioorganic&medicinal chemistry letters. 2011 May 1. 21(9): 2587-90. PMID# 21420295

Liu Zhiping, Sun Liou Y. Complex roles of Sirtuin 1 in cancer and aging. Translational research : the journal of laboratory and clinical medicine. 2011 May. 157(5): 273-5. PMID# 21497774

Cai Qian, Sun Haiying, Peng Yuefeng, Lu Jianfeng, Nikolovska-Coleska Zaneta, McEachern Donna, Liu Liu, Qiu Su, Yang Chao-Yie, Miller Rebecca, Yi Han, Zhang Tao, Sun Duxin, Kang Sanmao, Guo Ming, Leopold Lance, Yang Dajun, Wang Shaomeng. A Potent and Orally Active Antagonist (SM-406/AT-406) of Multiple Inhibitor of Apoptosis Proteins (IAPs) in Clinical Development for Cancer Treatment. Journal of medicinal chemistry. 2011 Apr 28. 54(8): 2714-26. PMID# 21443232

Meng He, Chen Guoan, Zhang Xiaojie, Wang Zhuwen, Thomas Dafydd G, Giordano Thomas J, Beer David G, Wang Michael M. Stromal LRP1 in Lung Adenocarcinoma Predicts Clinical Outcome. Clinical cancer research : an official journal of the American Association for Cancer Research. 2011 Apr 15. 17(8): 2426-33. PMID# 21325077

Alhazzazi Turki Y, Kamarajan Pachiyappan, Joo Nam, Huang Jing-Yi, Verdin Eric, D'Silva Nisha J, Kapila Yvonne L. Sirtuin-3 (SIRT3), a novel potential therapeutic target for oral cancer. Cancer. 2011 Apr 15. 117(8): 1670-8. PMID# 21472714

Samadder N Jewel, Mukherjee Bhramar, Huang Shu-Chen, Ahn Jaeil, Rennert Hedy S, Greenson Joel K, Rennert Gad, Gruber Stephen B. Risk of colorectal cancer in self-reported inflammatory bowel disease and modification of risk by statin and NSAID use. Cancer. 2011 Apr 15. 117(8): 1640-8. PMID# 21472711

Tao Jiong, Deng Nian Tao, Ramnarayanan Kalpana, Huang Baohua, Oh Hue Kian, Leong Siew Hong, Lim Seong Soo, Tan Iain Beehuat, Ooi Chia Huey, Wu Jeanie, Lee Minghui, Zhang Shenli, Rha Sun Young, Chung Hyun Cheol, Smoot Duane T, Ashktorab Hassan, Kon Oi Lian CD44-SLC1A2 Gene Fusions in Gastric Cancer. Science translational medicine. 2011 Apr 6. 3(77): 77ra30. PMID# 21471434

Shuman Andrew G, Light Emily, Olsen Stephen H, Pynnonen Melissa A, Taylor Jeremy M G, Johnson Timothy M, Bradford Carol R. Mucosal melanoma of the head and neck: predictors of prognosis. Archives of otolaryngology--head&neck surgery. 2011 Apr. 137(4): 331-7. PMID# 21502471

Shtein Roni M, Newton Duane W, Elner Victor M. Actinomyces infectious crystalline keratopathy. Archives of ophthalmology. 2011 Apr. 129(4): 515-7. PMID# 21482881

Warren Jeffrey S, Zhao Ying, Yung Raymond, Desai Anjali. Recombinant human erythropoietin suppresses endothelial cell apoptosis and reduces the ratio of bax to bcl-2 proteins in the aortas of apolipoprotein e-deficient mice. Journal of cardiovascular pharmacology. 2011 Apr. 57(4): 424-33. PMID# 21242808

Skarra Dana V, Goudreault Marilyn, Choi Hyungwon, Mullin Michael, Nesvizhskii Alexey I, Gingras Anne-Claude, Honkanen Richard E. Label-free quantitative proteomics and SAINT analysis enable interactome mapping for the human Ser/Thr protein phosphatase 5. Proteomics. 2011 Apr. 11(8): 1508-16. PMID# 21360678

Pediatrics & Communicable Diseases

Hoefele Julia, Nayir Ahmet, Chaki Moumita, Imm Anita, Allen Susan J, Otto Edgar A, Hildebrandt Friedhelm. Pseudodominant inheritance of nephronophthisis caused by a homozygous NPHP1 deletion. Pediatric nephrology (Berlin, Germany). 2011 Jun. 26(6): 967-71. PMID# 21258817

Zheng Kai, Mei Qiaozhu, Hanauer David A. Collaborative search in electronic health records. Journal of the American Medical Informatics Association : JAMIA. 2011 May 1. 18(3): 282-91. PMID# 21486887

Eisenberg Daniel, Freed Gary L, Davis Matthew M, Singer Dianne, Prosser Lisa A. Valuing Health at Different Ages: Evidence from a Nationally Representative Survey in the US. Applied health economics and health policy. 2011 May 1. 9(3): 149-56. PMID# 21506621

Sheppard K M, Padmanabhan V, Coolen L M, Lehman M N. Prenatal programming by testosterone of hypothalamic metabolic control neurones in the ewe. Journal of neuroendocrinology. 2011 May. 23(5): 401-11. PMID# 21418339

Olivadoti Melissa D, Weinberg Jason B, Toth Linda A, Opp Mark R. Sleep and fatigue in mice infected with murine gammaherpesvirus 68. Brain, behavior, and immunity. 2011 May. 25(4): 696-705. PMID# 21272632

Nasr Samya Z. Inducing sputum in patients with cystic fibrosis could be helpful, but is time-consuming and expensive. The Journal of pediatrics. 2011 May. 158(5): 862. PMID# 21482251

Hildebrandt Friedhelm, Benzing Thomas, Katsanis Nicholas. Ciliopathies. The New England journal of medicine. 2011 Apr 21. 364(16): 1533-43. PMID# 21506742

Hassan Fauziya, Davis Matthew M, Chervin Ronald D. No Independent Association between Insufficient Sleep and Childhood Obesity in the National Survey of Children's Health. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. 2011 Apr 15. 7(2): 153-7. PMID# 21509329

Gadepalli Samir K, Selewski David T, Drongowski Robert A, Mychaliska George B. Acute kidney injury in congenital diaphragmatic hernia requiring extracorporeal life support: an insidious problem. Journal of pediatric surgery. 2011 Apr. 46(4): 630-5. PMID# 21496529

Ness Kirsten K, Armenian Saro H, Kadan-Lottick Nina, Gurney James G. Adverse effects of treatment in childhood acute lymphoblastic leukemia: general overview and implications for long-term cardiac health. Expert review of hematology. 2011 Apr. 4(2): 185-97. PMID# 21495928

Pharmacology

Ohmura Yu, Jutkiewicz Emily M, Domino Edward F. L-DOPA attenuates nicotine withdrawal-induced behaviors in rats. Pharmacology, biochemistry, and behavior. 2011 Jun. 98(4): 552-8. PMID# 21354201

Kim Myung N, Jutkiewicz Emily M, Zhang Minjia, Gnegy Margaret E. The sensitizing effect of acute nicotine on amphetamine-stimulated behavior and dopamine efflux requires activation of ß2 subunit-containing nicotinic acetylcholine receptors and glutamate N-methyl-d-aspartate receptors. Neuropharmacology. 2011 Jun. 60(7-8): 1126-34. PMID# 20971124

Sridar Chitra, Snider Natasha T, Hollenberg Paul F. Anandamide Oxidation by Wild-Type and Polymorphically Expressed CYP2B6 and CYP2D6. Drug metabolism and disposition: the biological fate of chemicals. 2011 May. 39(5): 782-8. PMID# 21289075

Blazer Levi L, Zhang Haoming, Casey Emma M, Husbands Stephen M, Neubig Richard R. A nanomolar-potency small molecule inhibitor of regulator of g-protein signaling proteins. Biochemistry. 2011 Apr 19. 50(15): 3181-92. PMID# 21329361

Physical Medicine & Rehabilitation

Gruis Kirsten L, Wren Patricia A, Huggins Jane E. Amyotrophic lateral sclerosis patients' self-reported satisfaction with assistive technology. Muscle&nerve. 2011 May. 43(5): 643-7. PMID# 21462207

Seip Richard L, Zoeller Robert F, Angelopoulos Theodore J, Salonia James, Bilbie Cherie, Moyna Niall M, Miles Mary P, Visich Paul S, Pescatello Linda S, Gordon Paul M, Tsongalis Gregory J, Bausserman Linda, Thompson Paul D. Interactive effects of APOE haplotype, sex, and exercise on postheparin plasma lipase activities. Journal of applied physiology (Bethesda, Md. : 1985). 2011 Apr. 110(4): 1021-8. PMID# 21252218

Murphy Susan L. Update on geriatric research in productive aging. The American journal of occupational therapy. : official publication of the American Occupational Therapy Association. 2011 Mar-Apr. 65(2): 197-206. PMID# 21476367

Psychiatry

Fitzpatrick Christopher J, Knox Dayan, Liberzon Israel. Inactivation of the prelimbic cortex enhances freezing induced by trimethylthiazoline, a component of fox feces. Behavioural brain research. 2011 Aug. 221(1): 320-3. PMID# 21420435

Stein Karen Farchaus, Wing Jeffrey, Lewis Adam, Raghunathan Trivellore. An eating disorder randomized clinical trial and attrition: Profiles and determinants of dropout. The International journal of eating disorders. 2011 May. 44(4): 356-68. PMID# 21472754

Bohnert Amy S B, Zivin Kara, Welsh Deborah E, Kilbourne Amy M. Ratings of patient-provider communication among veterans: serious mental illnesses, substance use disorders, and the moderating role of trust. Health communication. 2011 Apr. 26(3): 267-74. PMID# 21390974

Swanson Leslie M, Pickett Scott M, Flynn Heather, Armitage Roseanne. Relationships among depression, anxiety, and insomnia symptoms in perinatal women seeking mental health treatment. Journal of women's health (2002). 2011 Apr. 20(4): 553-8. PMID# 21417746

Radiation Oncology

Janz Nancy K, Hawley Sarah T, Mujahid Mahasin S, Griggs Jennifer J, Alderman Amy, Hamilton Ann S, Graff John J, Jagsi Reshma, Katz Steven J. Correlates of worry about recurrence in a multiethnic population-based sample of women with breast cancer. Cancer. 2011 May 1. 117(9): 1827-36. PMID# 21445916

Xiong X, Zhao Y, He H, Sun Y. Ribosomal protein S27-like and S27 interplay with p53-MDM2 axis as a target, a substrate and a regulator. Oncogene. 2011 Apr 14. 30(15): 1798-811. PMID# 21170087

Radiology

Rauen Katherine A, Banerjee Anuradha, Bishop W Robert, Lauchle Jennifer O, McCormick Frank, McMahon Martin, Melese Teri, Munster Pamela N, Nadaf Sorena, Packer Roger J, Sebolt-Leopold Judith, Viskochil David H. Costello and cardio-facio-cutaneous syndromes: Moving toward clinical trials in RASopathies. American journal of medical genetics. Part C, Seminars in medical genetics. 2011 May 15. 157(2): 136-46. PMID# 21495172

Chung S-H, Choi S H, Cho K J, Joo C-K. Toll-like receptor 4 signalling attenuates experimental allergic conjunctivitis. Clinical and experimental immunology. 2011 May. 164(2): 275-81. PMID# 21391988

Kumon Ronald E, Deng Cheri X, Wang Xueding. Frequency-domain analysis of photoacoustic imaging data from prostate adenocarcinoma tumors in a murine model. Ultrasound in medicine&biology. 2011 May. 37(5): 834-9. PMID# 21376447

Al-Hawary Mahmoud M, Zimmermann Ellen M. Choosing the right cross-sectional imaging technique: Trading image quality for radiation risk. Inflammatory bowel diseases. 2011 May. 17(5): 1089-91. PMID# 21484960

Holloway Benjamin J, Agarwal Prachi P. Incidental cor triatriatum discovered on multidetector computed tomography. Journal of thoracic imaging. 2011 May. 26(2): W45-7. PMID# 20634761

Smith Ethan A, Dillman Jonathan R, Strouse Peter J. Xanthogranulomatous pyelonephritis: reply to Rao et al. Pediatric radiology. 2011 May. 41(5): 673-4. PMID# 21416221

Jorgensen Jennifer E, Waljee Akbar K, Volk Michael L, Sonnenday Christopher J, Elta Grace H, Al-Hawary Mahmoud M, Singal Amit G, Taylor Jason R, Elmunzer B Joseph. Is MRCP equivalent to ERCP for diagnosing biliary obstruction in orthotopic liver transplant recipients? A meta-analysis. Gastrointestinal endoscopy. 2011 May. 73(5): 955-62. PMID# 21316670

Pai Deepa R, Strouse Peter J. MRI of the pediatric knee. AJR. American journal of roentgenology. 2011 May. 196(5): 1019-27. PMID# 21512066

Srinivasan A, Mukherji S K. Tositumomab and iodine I 131 tositumomab (bexaar). AJNR. American journal of neuroradiology. 2011 Apr. 32(4): 637-8. PMID# 21436340

Shah H, Gemmete J J, Chaudhary N, Pandey A S, Ansari S A. Acute life-threatening hemorrhage in patients with head and neck cancer presenting with carotid blowout syndrome: follow-up results after initial hemostasis with covered-stent placement. AJNR. American journal of neuroradiology. 2011 Apr. 32(4): 743-7. PMID# 21436338

Sisson James C, Freitas John, McDougall Iain Ross, Dauer Lawrence T, Hurley James R, Brierley James D, Edinboro Charlotte H, Rosenthal David, Thomas Michael J, Wexler Jason A, Asamoah Ernest, Avram Anca M, Milas Mira, Greenlee Carol. Radiation safety in the treatment of patients with thyroid diseases by radioiodine 131i: practice recommendations of the american thyroid association. Thyroid : official journal of the American Thyroid Association. 2011 Apr. 21(4): 335-46. PMID# 21417738

Surgery

Surti S, Zou W, Daube-Witherspoon M E, McDonough J, Karp J S. Design study of an in situ PET scanner for use in proton beam therapy. Physics in medicine and biology. 2011 May 7. 56(9): 2667-85. PMID# 21464528

Wang Yin, Liu Yan, Malek Sami N, Zheng Pan, Liu Yang. Targeting HIF1¿ Eliminates Cancer Stem Cells in Hematological Malignancies. Cell stem cell. 2011 Apr 8. 8(4): 399-411. PMID# 21474104

Surgery – General Surgery

Breslin Tara M. Neoadjuvant chemotherapy for breast cancer: a surgeon's checklist. Breast cancer research and treatment. 2011 May. 127(1): 129-31. PMID# 21293920

Yu L-H, Lin Z-F, Liu Y, Hu F-Y, He X-H, Liu Z-L, Xu Y-M. The transcription factor Pitx3 is a risk modifier for Parkinson's disease in a Chinese Han population. European journal of neurology : the official journal of the European Federation of Neurological Societies. 2011 May. 18(5): 778-83. PMID# 21138504

Wang Yin, Liu Yan, Malek Sami N, Zheng Pan, Liu Yang. Targeting HIF1¿ Eliminates Cancer Stem Cells in Hematological Malignancies. Cell stem cell. 2011 Apr 8. 8(4): 399-411. PMID# 21474104

Wong Sandra L, Sabel Michael S, Johnson Timothy M. Sentinel lymph node biopsy for melanoma: one procedure but many questions: comment on "prognostic usefulness of sentinel lymph node biopsy for patients who have clinically node negative, localized, primary invasive cutaneous melanoma". Archives of dermatology. 2011 Apr. 147(4): 415-6. PMID# 21482891

Etzioni David A, Finlayson Samuel R, Ricketts Thomas C, Lynge Dana C, Dimick Justin B. Getting the science right on the surgeon workforce issue. Archives of surgery (Chicago, Ill. : 1960). 2011 Apr. 146(4): 381-4. PMID# 21502445

Surgery – Thoracic Surgery

Meng He, Chen Guoan, Zhang Xiaojie, Wang Zhuwen, Thomas Dafydd G, Giordano Thomas J, Beer David G, Wang Michael M. Stromal LRP1 in Lung Adenocarcinoma Predicts Clinical Outcome. Clinical cancer research : an official journal of the American Association for Cancer Research. 2011 Apr 15. 17(8): 2426-33. PMID# 21325077

Lau Darryl, Lin Jules, Park Paul. Cranial nerve III palsy resulting from intracranial hypotension caused by cerebrospinal fluid leak after paraspinal tumor resection: etiology and treatment options. The spine journal : official journal of the North American Spine Society. 2011 Apr. 11(4): e10-3. PMID# 21474076

Travis William D, Brambilla Elisabeth, Noguchi Masayuki, Nicholson Andrew G, Geisinger KimR, Yatabe Yasushi, Beer David G, Powell Charles A, Riely Gregory J, Van Schil Paul E, Garg Kavita, Austin John H M, Asamura Hisao, Rusch Valerie W, Hirsch Fred R, Sc International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2011 Feb. 6(2): 244-85. PMID# 21252716

Surgery – Transplantation Surgery

Jorgensen Jennifer E, Waljee Akbar K, Volk Michael L, Sonnenday Christopher J, Elta Grace H, Al-Hawary Mahmoud M, Singal Amit G, Taylor Jason R, Elmunzer B Joseph. Is MRCP equivalent to ERCP for diagnosing biliary obstruction in orthotopic liver transplant recipients? A meta-analysis. Gastrointestinal endoscopy. 2011 May. 73(5): 955-62. PMID# 21316670

Surgery – Vascular Surgery

Alvarado Christine M, Diaz Jose A, Hawley Angela E, Wrobleski Shirley K, Sigler Robert E, Myers Daniel D. Male mice have increased thrombotic potential: Sex differences in a mouse model of venous thrombosis. Thrombosis research. 2011 May. 127(5): 478-86. PMID# 21296387

Urology

Latini Jerilyn M, Giannantoni Antonella. Pharmacotherapy of overactive bladder: epidemiology and pathophysiology of overactive bladder. Expert opinion on pharmacotherapy. 2011 May. 12(7): 1017-27. PMID# 21473706

Johnson Emilie K, Hedgepeth Ryan C, He Chang, Wood David P. The impact of anterior urethropexy during robotic prostatectomy on urinary and sexual outcomes. Journal of endourology / Endourological Society. 2011 Apr. 25(4): 615-9. PMID# 21126190

Weizer Alon Z, Palella Gaetano V, Montgomery Jeffrey S, Miller David C, Hafez Khaled S. Robot-assisted retroperitoneal partial nephrectomy: technique and perioperative results( * ). Journal of endourology / Endourological Society. 2011 Apr. 25(4): 553-7. PMID# 21381954

Filson Christopher P, Redman Bruce G, Dunn Rodney L, Miller David C. Initial patterns of care with oral targeted therapies for patients with renal cell carcinoma. Urology. 2011 Apr. 77(4): 825-830.e1. PMID# 21256539

 


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