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SEPTEMBER 2010, Vol. 28

Goodbye “Biomedical News,” and hello “UMMS Research News!” In the interest of clarity, we’ve renamed the monthly online publication that’s your comprehensive source for updates, events, and happenings in research at the University of Michigan Medical School (UMMS).

For more information about what’s going on across the UM Medical Campus:

  • Health System Headlines connects you to what's happening daily throughout the Medical School, the Health System and the University.
  • UMHS Newsroom lists breaking news from the Health System.

Media inquiries about research at the UMMS? CLICK HERE


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HEADLINES

Researchpalooza – Connect with the labs and offices which are here to serve YOU!
Researchpalooza

Wednesday, September 15, 2010
11:00 AM - 2:00 PM
Circle Drive in front of Med Sci I

Games! Prizes! Ice Cream! Fun!

Join the UMMS Office of Research for our first-ever Researchpalooza during the annual Ice Cream Social. In addition to ice cream, popcorn, and lots of fun giveaways, the Office of Research is sponsoring prize drawings for…

  • Grand Prize – $2,000 for a trip to attend a research or professional development conference
  • 2nd  Prize – $1,000 toward hosting a research seminar, journal club, or invited speaker
  • 3rd Prize – $500 toward any one BRCF Core Service

PLUS great prizes from MICHR! One lucky faculty researcher will win $350 for registration at the FDA Clinical Investigator Training Course in November in Maryland, and a staff study coordinator will win the cost of certification for either the SoCRA or ACRP exams - up to a $440 value!

Join colleagues and friends as we meet, mingle, and learn more about many of the labs and offices that offer their stellar services to faculty, students, and staff, all at one convenient time and location! Exhibiting groups with tables on Circle Drive will include…

Affymetrix and cDNA Microarray Core
Biomedical Research Core Facilities
Biomedical Research Council
Biomedical Research Store
Business Development
Business Engagement Center
Center for Chemical Genomics
Center for Integrative Genomics
Center for Research on Learning and Teaching
Clinical Research Calendar Review & Analysis
Collexis Research Profiles
Division of Research Development & Administration
Electron Microbeam Analysis
ITS eResearch
Grant Review & Analysis
Hybridoma Core
Institutional Review Board
Life Sciences Institute
Medical Innovation Center
Medical School Information Services
Michigan Clinical Research Unit
Michigan Institute for Clinical & Health Research
Michigan Society for Medical Research
Microscopy & Image Analysis
North Campus Research Complex
Office of Research
Public Relations & Marketing Communications
Protein Structure Facility
Regulatory Affairs
Tech Transfer
Transgenic Animal Model Core
UM Clinical Studies
Undergraduate Research Opportunity Program
Unit for Laboratory Animal Medicine
University Committee on Use and Care of Animals
Vahlteich Medicinal Chemistry Core
Women in Science & Engineering

View the event flyer.

Need more info? Contact Ann Curtis in the Office of Research.

NIH SBIR/STTR Grants and Contracts: Interested but Not Sure What, Why and How?

Wednesday, September 8, 2010
8:00 a.m. and 4:00 p.m. (The same session is offered at two different times.)
M3330 Med Sci I

The UMMS Office of Research is sponsoring a one-hour overview session that will:

  • Provide an overview of SBIR/STTR grants and contracts and what they fund.
  • Discuss the similarities and differences between SBIR/STTR grants and basic research grants, such as NIH R01 and R21.
  • Describe a variety of different ways that faculty members can participate in SBIR/STTR funded projects.
  • Explain how investigators can receive additional State-funded assistance to help pursue SBIR/STTR funding.

This session will help you decide whether to consider these NIH funding mechanisms, and also whether to attend a more intensive two-day workshop to follow on September 30 - October 1, 2010 (http://www.bbcetc.com/training.html). The overview session is presented by Lisa M. Kurek, Managing Partner, BBCetc.  Contact Lisa at 734-930-9741 with any questions.

A Message from Dr. Ken Pienta on Clinical Research at UMHS: Strategic Assessment and Town Hall (September 29, 2010)

Dear Faculty and Staff,

I wanted to provide you with an update on the Strategic Assessment of the Clinical Research Enterprise (SACRE) that many of you participated in over the past year, and invite you to an interactive Town Hall on September 29, 2010 for more details.

As you may recall, SACRE was conducted from July 2009 through January 2010, involving interviews with 125 employees who are engaged in the clinical research process, and a web-based survey with 651 research faculty and staff respondents. The SACRE document, linked below, includes two sections: Phase I includes the assessment results, and Phase II presents recommendations and an implementation plan.

The assessment clearly identified eight key issues that need to be addressed, and the Michigan Institute for Clinical & Health Research (MICHR) is playing a lead role in addressing them. With the support of Dean Woolliscroft and EVPMA Ora Pescovitz, MICHR has made implementation of the SACRE recommendations an integral part of our overall FY2011 Strategic Plan.

The eight issues we are actively pursuing based on the assessment are:

  • Expedite the study approval/contracting process
  • Establish a clinical research support unit (CRSU) and "franchisable" best practices and tools
  • Develop end-to-end, user-friendly financial system for clinical researchers (budget, billing, and account reconciliation)
  • Improve regulatory processes
  • Create a home for study coordinators to promote education and sharing of best practices
  • Increase patient participation in clinical studies
  • Improve IT infrastructure
  • Change the clinical research culture

The full SACRE document, including the assessment results and implementation plan, is available on MICHR's website. I encourage you to review it and then attend the Town Hall where I'll provide a progress update and answer your questions.

Clinical Research Town Hall
Wednesday, September 29, 2010
12:00 - 1:00 PM
Ford Auditorium, Main Hospital

We look forward to working with you on making these improvements to the clinical research enterprise, and hope to see you at the Town Hall.

Best,

Ken Pienta, M.D.
Director, Michigan Institute for Clinical & Health Research
Associate Dean, Clinical & Translational Research

UMHS Clinical Research Position Statement and Template Language

The Medical School Office of Research is pleased to announce the release of a new position statement regarding the payment of research related injuries resulting from a clinical trial. The “UMHS Clinical Research Position Statement and Template Language” is effective as of September 1, 2010. The Office of Research has worked together with IRBMED and the Division for Research Development and Administration (DRDA) in drafting this statement. This is an important step in ensuring the financial safety of our valued research participants. It is essential that study teams understand and adopt this position as part of their interaction and negotiation with Industry sponsors. It is UMHS’s position that Industry sponsors should bear the costs for research related injuries, not only to avoid Medicare Secondary Payer (MSP) implications, but to relieve research participants of the financial burdens such as co-payments and deductibles that can be associated with clinical trial injury expenses. Federally funded projects do not provide provisions for subject injury; therefore, UMHS will pay for research related injury costs.

The Calendar Review & Analysis Office (CRAO) will continue reviewing for appropriate language in the draft Informed Consent and draft Contract. However, it is DRDA that will play a key role in negotiating contract language with Industry sponsors. DRDA will work with the study teams and sponsors to make sure the contract language reflects this position statement.

Please note that the UMHS Clinical Research Position Statement and Template Languag document can be accessed via U-M computers only and computers that are logged in via a VPN (Virtual Private Network).

Making the Cut: Research Proposal Writing from the Reviewers’ Perspectives

Wednesday, October 13, 2010
8:30 AM - 12:00 PM
Dow Auditorium, Towsley Center

Presenter: Christine K. Black, Assistant Director of Research Services, Medical School Office of Research

This workshop is an overview of research grant proposal development. Topics include:  funding opportunity databases and matching funders’ priorities; considerations in project design; and writing for relevancy, persuasion, and rave reviews. Proposals to both federal and foundation sources will be covered. During the last half-hour, a panel of successfully-funded faculty members will join us and answer questions about proposal writing.

If you have a question in advance of the workshop, you may include it on the registration form.

This workshop is sponsored by the Medical School Office of Research. Please note that if this date is inconvenient for you, a similar workshop sponsored by DRDA will be presented by Chris Black on Tuesday, November 2, 2010 (view details here).

Contact Kathryn Ridner (kridner@umich.edu or 734-763-4086) with any questions.

BMRC Bridging Support Program for Biomedical Research
Deadline: Wednesday, September 15, 2010

The Medical School’s Office of Research brings your attention to a re-prioritization of the BMRC Bridging Support Program for Biomedical Research.  Bridging Support provides funding for federally funded biomedical research projects with a demonstrated likelihood of continued funding after resubmission (up to $40,000 for one year from the BMRC with required matching from the PI's department).  In consideration of the reduction of NIH resubmission opportunities (from two to one), the program will focus on bridging a non-funded gap of time during preparation of an A1 application, will cease to support any new grants, and will not consider previous special circumstances (e.g., first R01s following a non-renewable award, such as a K08 or R21; or R01s that spun off independently from a Program Project).

To be eligible, the PI must have submitted the renewal grant and received the reviewers' summary statement in preparation of a resubmission.  Eligibility is also limited to full-time, on-campus instructional and research faculty with primary appointments in the Medical School.  Grants to be bridged must reside in the Medical School.

The bridging application deadlines are January 15, June 15, and September 15.  Please refer to the website for more details.  If you have questions, please contact Camille Mrozowski.


SEMINARS + MAJOR EVENTS AND CONFERENCES

Please visit the calendar links on the right side menu to make sure you're "in the loop" with current events!


RESEARCH COMPLIANCE TRAINING AND EDUCATION


Animal Research

Public Opinion and the Use of Animals in Research

Wednesday, September 22, 2010
1:00 - 2:30 PM
Kahn Auditorium - Biomedical Science Research Building (BSRB)

Please join us for a special grand rounds presentation on the topic of “Public Opinion and the Use of Animals in Research” to be given by Paul McKellips, Executive Vice President, Foundation for Biomedical Research, Washington, DC.  This presentation is hosted by the Michigan Society for Medical Research (MISMR), and the University of Michigan Medical School’s Office of Research, Office of Regulatory Affairs, and Unit for Laboratory Animal Medicine (ULAM).

eRAM Is Coming – Complete Your Amendments and Applications

With the upcoming move into eResearch Animal Management (eRAM), we would like to encourage everyone to submit and complete UCUCA amendments and renewal applications as soon as possible to prevent delays in approval. The University Committee on Use and Care of Animals (UCUCA) requests that protocols be submitted a minimum of three months prior to the expiration date to ensure that there is adequate time to prevent lapses in approval. Conducting animal activities – including housing, breeding, interventions/ experimental manipulations, and euthanasia – after a protocol has expired is a violation of National Institutes of Health (NIH) grants Policy, as well as the Public Health Service (PHS) Policy.

UCUCA – Check Us Out at Researchpalooza!

The University Committee on Use and Care of Animals (UCUCA) will be participating in the Researchpalooza on September 15, 2010 from 11:00 a.m. - 2:00 p.m. in the circle drive in front of Med Sci I.  Come meet your compliance associates and the ITS eResearch Animal Management Team!

AAALAC Is on the Horizon – Help Us Achieve Excellence

The University Committee on Use and Care of Animals (UCUCA) is scheduled to have their triennial inspection by the Association for Assessment and Accreditation of Laboratory Animal Care, International in the first quarter of 2011.  AAALAC's voluntary accreditation process allows research programs to demonstrate that they meet the minimum standards required by law, and are also going the extra step to achieve excellence in animal care and use. Please let us know as soon as possible if any changes need to be made to your protocol. More information regarding the site visit will be made available in the coming months.

If you ever have any questions regarding the UCUCA or anything else related to your animal work or compliance, please do not hesitate to contact the UCUCA Office (ucuca.office@umich.edu or 734-763-8028).


EDUCATIONAL OPPORTUNITIES


FDA Clinical Investigator Training Course

November 8 - 10, 2010
National Labor College
10000 New Hampshire Avenue
Silver Spring, Maryland  20903

Course Fee: $ 350

The second annual FDA Clinical Investigator Training Course, co-sponsored by the Food and Drug Administration's (FDA) Office of Critical Path Programs and the Clinical Trials Transformation Initiative (CTTI), is now open for registration.

This intensive, three-day course will enable clinical investigators to gain a greater appreciation of the scientific, ethical, and regulatory issues relating to clinical trial data that may be submitted to regulatory bodies. Attendees will have the unique opportunity of hearing directly from FDA's nationally renowned experts on issues critical to successful clinical research.

Topics to be discussed include the design, conduct, and analysis of clinical trials; regulatory considerations essential for clinical research; the role of the DSMB and IRB in clinical studies; preclinical and pharmacological issues in clinical studies; safety assessment during clinical trials; inclusion of special populations such as pregnant women in clinical studies; and the role of personalized medicine in the future of medical product development. The course has been designed with the goal of enabling investigators to improve the quality of clinical trials and to enhance the safety of trial participants.

Visit the website for more information and to register.


GRADUATE AND POSTDOC STUDIES


Graduate Student Awards Ceremony and Ice Cream Social

Thursday, September 23, 2010
3:00 - 4:30 PM
MSRB III / Med Sci II Courtyard (In case of rain: 2955 Taubman Medical Library-GAPS Conference Room/Lounge)

The Graduate Student Council (GSC) cordially invites you to the Graduate Student Awards Ceremony and Ice Cream Social. The Graduate Student Awards for Excellence in (1) Research and (2) Teaching and Service will be presented. Please contact PIBS at 734-647-7005 for further information.


KUDOS


Massimo Pietropaolo Garners a $3.3M NIH Grant for Type 1 Diabetes Research
Pietropaolo

Congratulations go to Massimo Pietropaolo, M.D., Professor of Internal Medicine and Professor of Pediatrics and Communicable Diseases, who is the PI on an R01 grant titled "Enhancement of Biomarkers for Type 1 Diabetes.”  The grant was funded to the tune of $3.3 million dollars to develop new studies on Type 1 diabetes at the University of Michigan in collaboration with other institutions.

“I believe that this is very important news for the Brehm Center for Diabetes Research, in its infancy,” says Dr. Pietropaolo. “I think that this achievement could give the opportunity to create new collaborations, and new grants, for the community as a whole.”

Project Summary / Abstract

The proposed research, based on our prior eight-year achievements, will investigate the role of new immunologic biomarkers in the largest population-based cohort of first degree relatives of T1DM patients with and without T1DM from the same geographical area. Growing number of pilot trials for T1DM are being conducted by international collaborative clinical research networks, such as TrialNet (http://www.diabetestrialnet.org) and the Immune Tolerance Network (http://www.immunetolerance.org) in an effort to find the cure for T1DM. There are many prevention trials in the pipeline that cannot be performed because the currently available biomarkers cannot identify a sufficient number of individuals to be enrolled in these trials. Endless discussions have taken place on how to develop new strategies to enhance sensitivity of multiple markers and in turn effectively enroll first-degree relatives in T1DM prevention trials.

Based on our most recent preliminary data, a major hypothesis of the present application is that a combination of novel biomarkers detecting antibodies directed to IA-2, GAD65 specific epitopes and the newly discovered antigen ZnT8 will further enhance sensitivity and the predictive value of T1DM progression as compared to conventional islet autoantibody markers. The proposed research will be performed at the University of Michigan using the Children’s Hospital of Pittsburgh cohort, which currently has 161 first degree relatives, who converted to insulin-requiring diabetes during follow-up (converters) from a pool of over 10,000 relatives of T1DM probands. This unique serum sample archive is ideal to test our immunologic hypotheses.  This represents the largest number of converters of any center and as such, more than 200 converters should be available by the end of the next grant period. Because it is impossible to have access to pancreatic tissue and pancreatic lymph nodes from subjects at risk of developing T1DM, we feel that it is entirely appropriate to develop predictive models of pancreatic b cell destruction to understand the role of pathogenic T cell responses during the natural history of human disease. We have constructed mathematical models taking into consideration new and conventional islet autoantibody biomarkers (Specific Aim I) and high avidity T cells which leads to b cell destruction during T1DM progression (Specific Aim II). We have coupled laboratory-based methodology with mathematical modeling of T1DM progression and have assembled an unprecedented team of leading experts in immunology research and mathematical predictive models of b cell destruction. Modeling key elements of T1DM progression (islet autoantibodies, T cell avidity, ER stress and UPR interactions) fits well with the experimental design and may ultimately validate a subset of T cells and/or the UPR pathway as drug targets and prove useful in guiding drug discovery to treat T1DM. The outcome of the proposed investigation should allow for the development of new biomarkers, modeling of key elements associated with T1DM progression and facilitate major clinical trials aimed at evaluating new approaches for understanding, preventing and treating Type 1 diabetes.

Project Narrative

The use of molecular immunology-based  research can be applied to reliably identify the earliest signs of islet autoantibodies which indicates that the autoimmune process leading to pancreatic beta cell injury has already initiated. It is likely that the appearance of these white cells contribute to the destructive process of pancreatic beta cells, a prelude of clinically overt Type 1 diabetes mellitus. Our research has major public health implications and together with modeling of key elements of Type 1 diabetes progression these studies will also provide a conceptual framework for designing new algorithms used for enrolling new subjects at risk in major clinical trials aimed at preventing Type 1 diabetes.


FUNDING / AWARD OPPORTUNITIES

Abstracts listed here are general information about these funding programs. We strongly urge interested applicants to visit the listed website to verify complete eligibility, program information, and application procedures before submitting an application.

Follow this link to search for other funding and recognition opportunities. This webpage contains information on email alert groups, internal grant programs, upcoming limited submissions, and links to extramural funding search engines.


Internal Submissions

UM Comprehensive Cancer Center Grants
Deadline: First Thursday of each month (4:00 PM) as funds are available.

(Grants may not be reviewed in a given month if too few are received. Grants are not reviewed in July and August.)

The UM Comprehensive Cancer Center's Cancer Research Committee invites applications from faculty requesting support for investigator-initiated research proposals that focus on the cancer problem or that have clear cancer relevance. For further information, visit (http://sitemaker.umich.edu/cccresearchgrants/home).

  • Research Grants are available for an investigator for cancer-related research, or for any interesting and innovative collaboration between scientists. The fund is available for faculty in any unit of the University. The total amount requested must not exceed $40,000.
  • Idea Grants are available for an investigator who has a novel and innovative idea for cancer research. Preliminary data to support the feasibility of the proposed studies are not required. However, preliminary data may be helpful in assessing the merits of the application and applicants are encouraged to include preliminary data if they are available. Funding will not exceed $30,000.


External Limited Submissions


These are opportunities in which the sponsor has limited the number of proposals allowed from an institution. These competitions require an internal review to select the proposals to submit to the sponsor from the University of Michigan.

Fred Hutchinson Cancer Research Center Harold M. Weintraub Graduate Student Award
Deadline: December 15, 2010

The Harold M. Weintraub Graduate Student Award recognizes outstanding achievement during graduate studies in the biological sciences. Awardees will participate in a scientific symposium honoring Hal Weintraub and his commitment to innovative science. The award symposium will consist of scientific presentations by the graduate student awardees and informal gatherings of students and faculty. The graduate student awardees are expected to be advanced students near the completion of their studies. Nominated students should not have graduated before September 2010. The Fred Hutchinson Weintraub and Groudine Fund, established to foster intellectual exchange through the promotion of programs for graduate students, fellows and visiting scholars, will cover expenses for the graduate student awardees. Only one nomination may be submitted per department or program. Visit the website for complete information.


Deadline Watch

Click here to view.

Hartwell Foundation Postdoctoral Fellowship
Internal Deadline: September 15, 2010

website
Contact Kathryn Ridner at 734-763-4086 or (kridner@umich.edu) with any questions.


Center for Organogenesis - Research Team Program - New Pilot Funding
Deadline: September 15, 2010 (Letter of Intent)

website


The Greenwall Foundation Faculty Scholars Program in Bioethics
Internal Deadline: October 1, 2010
Foundation Deadline: November 1, 2010 (Preliminary Application)

website
Direct any questions to Jane Ritter at (ritterj@umich.edu) or 734-763-1290.


Grants for Early Medical/Surgical Subspecialists’ Transition to Aging Research (R03)
Deadline: October 3, 2010 (Letter of Intent)

website
Jeffrey Halter, Director of the Geriatrics Center and Institute of Gerontology at UM, can answer questions about this program, facilitate applications, etc. He can be reached at (jhalter@umich.edu).


University Research Corridor Funding Opportunity in Environmental Health Science
Deadline: October 11, 2010 (5:00 PM) – Letter of Intent

website
Please direct any questions to Vince Nystrom (vincenystrom@urcmich.org).


Michigan Society of Fellows Postdoctoral Fellowships
Deadline: October 18, 2010 (1:00 PM EDT)

website


UMMS AWARDED GRANTS

External Awarded Grants

An asterisk next to a name means that they are the Contact PI for the program, since some projects are awarded with multiple PIs.

Click here to view.

Biological Chemistry

PI: *Fuller,Robert
Title: Purification and biochemical function of yeast Vps13 protein
Sponsor: Advocacy for Neuroacanthocytosis Patients
Project Dates and Amount of Award: 08/01/10-07/31/11; $42,000

Cell & Developmental Biology

PI: *Engel,James
Title: Development of Molecular Intervention Therapy for Sickle Cell Disease
Sponsor: American Heart Association, Midwest Affiliate
Project Dates and Amount of Award: 07/01/10-06/30/12; $90,772

PI: *Engel,James
Title: 5th International Conference on GATA Factors: GATA Factors in Development and Disease
Sponsor: The Company Biologists Limited
Project Dates and Amount of Award: 08/01/10-07/31/11; $4,580

PI: *Fingar,Diane
Title: Role of Raptor Phosphorylation in mTORC1 Signaling
Sponsor: American Heart Association, Midwest Affiliate
Project Dates and Amount of Award: 07/01/10-06/30/12; $143,000

Comprehensive Cancer Center

PI: *Khan,Gazala
Title: A Phase 1 Dose-Escalation Study of Oral ARRY-438162 in Patients with Advanced Solid Tumors Followed by an Expansion Cohort in Patients with Advanced or Metastatic Biliary Cancer
Sponsor: Array BioPharma
Project Dates and Amount of Award: 06/07/10-02/29/12; $577,813

PI: *Talpaz,Moshe
Co-I: Lebovic, Daniel (Int Med-Hematology/Oncology)
Title: AN OPEN-LABEL, MULTICENTER, PHASE I TRIAL OF THE SAFETY AND PHARMACOKINETICS OF ESCALATING DOSES OF DCDT2980S IN PATIENTS WITH RELAPSED OR REFRACTORY B-CELL NON-HODGKIN'S LYMPHOMA AND CHRONIC LYMPHOCYTIC LEUKEMIA
Sponsor: Genentech, Inc.
Project Dates and Amount of Award: 06/30/10-01/31/13; $2,669,395

PI: *Talpaz,Moshe
Co-I: Bixby, Dale (Int Med-Hematology/Oncology)
Title: An Open Label, Time-To-Event Continuous Reassessment Method, Phase I/II  Study of the Mammalian Target of Rapamycin (mTOR) Inhibitor RAD001 in Combination with Imatinib (Gleevec) in Patients with Chronic Phase Chronic Myeloid Leukemia (CML) with Persistent Molecular Disease.
Sponsor: Novartis
Project Dates and Amount of Award: 08/11/10-12/31/13; $349,999

Dermatology

PI: *Anderson,Thomas
Title: Phase IV Randomized, Study of Two Dose Levels of Targretin Capsules in Patients with Refractory Cutaneous T-Cell Lymphoma (Derm 621)
Sponsor: Premier Research TO Eisai, Inc
Project Dates and Amount of Award: 08/04/10-11/30/11; $95,334

PI: *Fisher,Gary
Co-I: Wang, Frank (Dermatology Department)
Title: Molecular pathogenesis of Striae Gravidarum
Sponsor: Dermatology Foundation
Project Dates and Amount of Award: 07/01/10-06/30/11; $30,000

Emergency Medicine

PI: *Rogers,Alexander
Title: CCS- CONSENT CONSTRUCT SURVEY
Sponsor: Blue Cross Blue Shield of Michigan Foundation TO Spectrum Health
Project Dates and Amount of Award: 01/01/10-12/31/10; $5,001

Internal Medicine

PI: *Aronoff,David
Title: Reglation of Uterine Epithelial Cell Antimicrobial Peptide Expression by Lipid Mediators
Sponsor: Infectious Diseases Society of America
Project Dates and Amount of Award: 07/01/10-06/30/11; $2,000

PI: *Bates,Eric
Title: A Clinical Outcomes Study of Darapladib Versus Placebo in Subjects Following Acute Coronary Syndrome to Compare the Incidence of Major Adverse Cardiovascular Events
Sponsor: Glaxosmithkline TO Brigham and Women's Hospital
Project Dates and Amount of Award: 06/29/10-01/31/14; $117,780

PI: *Bernal-Mizrachi,Ernesto
Co-I: Cras-Meneur, Corentin (Metabolism, Endo & Diabetes)
Title: In Vivo Reprogramming of Acinar Cells to Beta-Cells
Sponsor: Juvenile Diabetes Research Foundation International (JDRF)
Project Dates and Amount of Award: 09/01/10-08/31/13; $750,000

PI: *Chen,Yuqing
Title: TheProtective Role of KLF11 as a PPARgamma Co-Factor in Vascular Lesion Formation
Sponsor: American Heart Association, Midwest Affiliate
Project Dates and Amount of Award: 07/01/10-06/30/12; $95,224

PI: *Chetcuti,Stanley
Title: A Randomized, Partially-Blinded, Multi-Center, Active-Controlled, Dose-Ranging Study Assessing the Safety, Efficacy, and Pharmacodynamics of the REG1 Anticoagulation System Compared to Unfractionated Heparin or Low Molecular Heparin in Subjects with Acute Coronary Syndrome
Sponsor: Regado Biosciences, Inc. TO Clinsys Clinical Research, Inc.
Project Dates and Amount of Award: 05/26/10-06/30/11; $59,616

PI: *Conjeevaram,Hari
Title: A Phase II Double-Blind, Placebo-Controlled Study of Two Doses of EPA-E in Patients with NASH Protocol# MCH-02-001
Sponsor: Mochida Pharmaceutical Co., Lt TO Medpace, Inc
Project Dates and Amount of Award: 08/05/10-08/31/12; $169,000

PI: *Donato,Nicholas
Co-I: Jakubowiak, Andrzej (Int Med-Hematology/Oncology)
Title: Targeted Inhibition of Deubiquitinase Activity for Multiple Myeloma Therapy
Sponsor: Leukemia and Lymphoma Society
Project Dates and Amount of Award: 10/01/10-09/30/13; $600,000

PI: *Erba,Harry
Title: 2010.028:  The TOPAZ Study: A Long Term Extension Study in Elderly Subjects with Relapsed/Refractory Acute Myeloid Leukemia to Allow Continued Therapy with Tosedostat
Sponsor: Chroma Therapeutics, Ltd
Project Dates and Amount of Award: 07/19/10-07/31/14; $75,135

PI: *Erba,Harry
Title: 2009.022:  A Single Arm Phase II, Open-Label Study to Determine the Efficacy of 100mg Twice Daily Oral Dosing of Midostaurin Administered to patients with Aggressive Systemic Mastocytosis or Mast Cell Leukemia +/- an Associated Hematological Clonal Non-M
Sponsor: NOVARTIS PHARMA, INC.
Project Dates and Amount of Award: 08/13/10-12/01/12; $253,072

PI: *Ganesh,Santhi
Title: Genetics of Vascular Remodeling
Sponsor: NIH  4 R00 HL 089413 02
Project Dates and Amount of Award: 08/02/10-06/30/13; $746,998

PI: *Grossman,Paul
Title: ENGINEERING CAPILLARIES NETWORK
Sponsor: NIH - Subcontracts TO Harvard University  R01 HL 069957 05
Project Dates and Amount of Award: 05/13/10-04/30/11; $157,454

PI: *Gruber,Stephen
Co-I: Mukherjee, Bhramar (Biostatistics Department)
Title: TRANSDISCIPLINARY STUDIES OF GENETIC VARIATION IN COLORECTAL CANCER
Sponsor: NIH  1 U19 CA 148107 01
Project Dates and Amount of Award: 08/01/10-06/30/14; $9,974,055

PI: *Hayes,Daniel
Title: Financial Support for the Breast Cancer Intergroup Correlative Science Studies
Sponsor: Breast Cancer Research Fdn
Project Dates and Amount of Award: 10/01/10-09/30/11; $350,000

PI: *Herman,William
Co-I: Kim, Catherine (Int Med-General Medicine)
Title: Translating Research Into Action for Diabetes (TRIAD) Legacy Study (U58)
Sponsor: CDC 1 U58 DP 002645 01
Project Dates and Amount of Award: 07/12/10-07/11/13; $429,998

PI: *James,Mary
Co-I: Fries, Brant (Health Management and Policy)
Title: Arkansas Universal Assessment Project
Sponsor: Health and Human Services, Department of-Centers for Medicare and Medicaid Services-Subcontracts TO Arkansas, State of
Project Dates and Amount of Award: 10/01/10-06/30/11; $161,689

PI: *Keshamouni,Venkateshwar
Co-I: Fox, David (Int Med-Rheumatology) / Hogaboam, Cory (Pathology Department) / Kunkel, Steven (Pathology Department) / Lukacs, Nicholas (Pathology Department) / Lundy, Steven (Int Med-Rheumatology) / Moore, Bethany (Int Med-Pulm./Critical Care) / Standiford, Theodore (Int Med-Pulm./Critical Care)
Title: INCUCYTE: A LIVE-CELL IMAGING SYSTEM THAT FITS INTO STANDARD CO2-INCUBATOR
Sponsor: NIH  1 S10 RR 027525 01
Project Dates and Amount of Award: 07/01/10-06/30/11; $155,465

PI: *Koenig,Ronald
Co-I: Burant, Charles (Metabolism, Endo & Diabetes) / Giordano, Thomas (Pathology Department) / Sartor, Maureen (Computational Medicine and Bio)
Title: PAX8-PPARGAMMA REGULATION OF TRANSCRIPTION AND METABOLISM IN THYROID CANCER
Sponsor: NIH  1 R01 CA 151842 01
Project Dates and Amount of Award: 08/01/10-06/30/15; $1,717,289

PI: *Kolias,Theodore
Title: Radiofrequency-Based Speckle Tracking Echocardiography to Evaluate Diastolic Function
Sponsor: NIH - Subcontracts TO Pixel Velocity
Project Dates and Amount of Award: 05/01/10-10/31/10; $100,198

PI: *Kretzler,Matthias
Title: TARGETING RENAL INFLAMMATORY PATHWAYS OF SLE NEPHRITIS IN MOUSE AND MAN
Sponsor: NIH - Subcontracts TO North Shore-Long Island Jewish Health System  R01 DK 085241
Project Dates and Amount of Award: 08/01/10-03/31/11; $191,940

PI: *Lama,Vibha
Title: Cellular and Biochemical Modulation of Inflammation and Fibrosis in Systemic Sclerosis
Sponsor: Scleroderma Foundation
Project Dates and Amount of Award: 05/01/10-04/30/11; $50,000

PI: *Levine,John
Title: A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study of the Safety and Efficacy of orBec (Oral Beclomethasone 17,21-Dipropionate) in Conjunction with Ten Days of High-Dose Prednisone Therapy in the Treatment of Patients with Gastrointestinal Graft vs. Host Disease: UMCC 2010.038
Sponsor: Soligenix, Inc
Project Dates and Amount of Award: 08/20/10-07/31/13; $162,393

PI: *Merajver,Sofia
Title: Targeting RhoC in Breast Cancer: Novel Drugs, Mathematical Models and Epidemiological Studies in North Africa
Sponsor: Breast Cancer Research Fdn
Project Dates and Amount of Award: 10/01/10-09/30/11; $223,000

PI: *Merchant,Juanita
Title: Mechanisms of Gastrointestinal Growth and Transformation
Sponsor: NIH  2 R56 DK 055732 11
Project Dates and Amount of Award: 08/01/10-07/31/11; $368,861

PI: *Miller,Richard
Co-I: Cartee, Gregory (School of Kinesiology) / Galecki, Andrzej (Int Med-Geriatric Medicine) / Herzog, Susan (Molec & Integrative Physiology) / Keller, Evan (Urology Surgery) / Lombard, David (Pathology Department) / Pletcher, Scott (Molec & Integrative Physiology) / Wessells, Robert (Int Med-Geriatric Medicine)
Title: CELLULAR AND MOLECULAR BIOLOGY OF AGING
Sponsor: NIH  2 P30 AG 013283 16
Project Dates and Amount of Award: 08/15/10-06/30/15; $3,072,403

PI: *Moore,Bethany
Title: Alpha3Beta1 Integrin Function in Epithelial-Mesenchymal Transition and Fibrosis
Sponsor: NIH  7 K08 HL 085290 04
Project Dates and Amount of Award: 09/01/10-06/30/12; $248,858

PI: *Pelosi Jr,Frank
Title: Boston Scientific Foundation 2010 EP Fellowship Program
Sponsor: Boston Scientific Foundation
Project Dates and Amount of Award: 07/01/10-06/30/11; $40,000

PI: *Pelosi Jr,Frank
Title: Medtronic 2010 EP Fellowship Program
Sponsor: Medtronic, Inc.
Project Dates and Amount of Award: 07/01/10-06/30/11; $40,000

PI: *Peters-Golden,Marc
Title: Role of Leukotrienes in Mediating MyD88-Induced NFkappaB Activation: from the Plasma Membrane to the Nucleus.
Sponsor: American Heart Assoc, Inc.
Project Dates and Amount of Award: 07/01/10-06/30/14; $308,000

PI: *Peters-Golden,Marc
Co-I: Linderman, Jennifer (Biomedical Engineering) / Neubig, Richard (Pharmacology Department) / Nunez, Gabriel (Pathology Department) / Serezani, Carlos (Int Med-Pulm./Critical Care)
Title: Regulation of Toll-like receptor-induced NFkB activation by Gai-coupled receptors
Sponsor: NIH  1 K99 HL 103777 01
Project Dates and Amount of Award: 09/01/10-06/30/12; $242,108

PI: *Petty,Elizabeth
Co-I: Nejedlik, Laura (Int Med-Molecular Med&Genetics)
Title: NUCLEAR SEPT9 AND JNK REGULATION IN BREAST CANCER
Sponsor: US DOD-Army, Department of the
Project Dates and Amount of Award: 04/17/10-08/14/13; $237,128

PI: *Pietropaolo,Massimo
Co-I: Nelson, Patrick (Comp Med and Bioinformatics) / Schnell, Santiago (Molec & Integrative Physiology) / Towns, Roberto (Metabolism, Endo & Diabetes)
Title: Enhancement of Biomarkers for Type 1 Diabetes
Sponsor: NIH  2 R01 DK 053456 09 A2
Project Dates and Amount of Award: 07/19/10-06/30/15; $3,237,402

PI: *Pop-Busui,Rodica
Title: Targeting Inflammation to Improve Endothelial Function in Type 2 Diabetes: A Substudy of TINSAL-T2D
Sponsor: NIH - Subcontracts TO Brigham and Women's Hospital
Project Dates and Amount of Award: 01/01/10-12/31/10; $16,841

PI: *Rae,James
Co-I: Hayes, Daniel (Int Med-Hematology/Oncology)
Title: Pharmacogenomic Predictors of Breast Cancer Endocrine Response
Sponsor: Breast Cancer Research Fdn
Project Dates and Amount of Award: 10/01/10-09/30/11; $223,000

PI: *Redman,Bruce
Title: A Multicenter, Open-Label, Dose-Escalation, Phase 1 Study of TAK-733, an Oral MEK Inhibitor, in Adult Patients with Advanced Nonhematologic Malignancies
Sponsor: Millennium Pharm, Inc.
Project Dates and Amount of Award: 07/01/10-07/01/12; $411,080

PI: *Rubenstein,Joel
Co-I: Beecher, Christopher (Ctr fr Translational Pathology) / Kim, Sinae (Biostatistics Department)
Title: Metabolome Risk Factors for Barrett's Esophagus
Sponsor: NIH  1 R03 DK 089150 01
Project Dates and Amount of Award: 08/01/10-06/30/12; $155,000

PI: *Saran,Rajiv
Co-I: Gillespie, Brenda (Ctr Statistical Consul & Res) / Hummel, Scott (Int Med-Cardiology) / Perlman, Rachel (Int Med-Nephrology)
Title: ESTABLISHMENT OF A COLLABORATIVE FOR CLINICAL TRANSLATIONAL RESEARCH BETWEEN THE RENAL RESEARCH INSTITUTE (RRI) AND THE UM-KIDNEY EPIDEMIOLOGY AND COST
Sponsor: Renal Research Institute, LLC
Project Dates and Amount of Award: 01/01/10-12/31/10; $237,400

PI: *Schiopu,Elena
Title: Raynaud's Phenomenon Phosphodiersterase 5 Inhibitor PF-00489791(VAMPS).
Sponsor: Pfizer Incorporated TO ICON Clinical Research, Inc.
Project Dates and Amount of Award: 07/27/10-07/31/12; $183,875

PI: *Urba,Susan
Title: Schwartz Center Rounds
Sponsor: Schwartz, Kenneth B., Center
Project Dates and Amount of Award: 07/01/10-06/30/11; $7,121

PI: *Wang,Shaomeng
Title: Development of Novel Anticancer Drugs
Sponsor: Ascenta Therapeutics
Project Dates and Amount of Award: 10/01/09-12/31/09; $50,000

PI: *Wang,Shaomeng
Co-I: Lu, Jianfeng (Int Med-Hematology/Oncology) / Mceachern, Donna (Int Med-Hematology/Oncology) / Sun, Haiying (Int Med-Hematology/Oncology)
Title: Design and Development of New Therapy for the Treatment of Human Breast Cancer by Overcoming Apoptosis Resistance of Breast Cancer Cells
Sponsor: Breast Cancer Research Fdn
Project Dates and Amount of Award: 10/01/10-09/30/11; $223,000

PI: *Wicha,Max
Title: Targeting the Breast Cancer Stem Cell Microenvironment
Sponsor: Breast Cancer Research Fdn
Project Dates and Amount of Award: 10/01/10-09/30/11; $222,997

PI: *Young,Vincent
Co-I: Aronoff, David (Int Med-Infectious Diseases) / Galecki, Andrzej (Int Med-Geriatric Medicine) / Hanna, Philip (Microbiology and Immunology) / Huffnagle, Gary (Int Med-Pulm./Critical Care) / Janes, Brian (Microbiology and Immunology) / Kao, John (Int Med-Gastroenterology) / Li, Jun (Human Genetics Department) / Schloss, Patrick (Microbiology and Immunology) / Washer, Laraine (Int Med-Infectious Diseases)
Title: Clostridium Difficile Cooperative Research Center
Sponsor: NIH  1 U19 AI 090871 01
Project Dates and Amount of Award: 08/02/10-07/31/15; $7,614,615

PI: *Yung,Raymond
Co-I: Grolleau-Julius, Annabelle (Int Med-Geriatric Medicine) / Richardson, Bruce (Int Med-Rheumatology)
Title: LEUKOCYTE-ENDOTHELIAL CELL INTERACTION IN AGAIN
Sponsor: NIH  2 R01 AG 0206288 06 A2
Project Dates and Amount of Award: 09/01/10-08/31/15; $1,534,972

Medical Education

PI: *Gruppen,Larry
Title: AMA ISTEP
Sponsor: Amer. Medical Association
Project Dates and Amount of Award: 06/16/10-05/31/13; $45,000

Microbiology and Immunology

PI: *Mobley,Harry
Title: MOLECULAR PATHOGENESIS OF E. COLI UTI
Sponsor: NIH  3 R01 AI 043363 13 S1
Project Dates and Amount of Award: 08/09/10-08/08/11; $67,527

PI: *Swanson,Joel
Title: SOFTWARE AND INSTRUMENTATION FOR 3D-IMAGING OF MULTIPLE MOLECULAR INTERACTIONS IN LIVING CELLS
Sponsor: National Science Foundation-Subcontracts TO South Dakota State University
Project Dates and Amount of Award: 08/01/10-07/31/12; $15,000

PI: *Telesnitsky,Alice
Co-I: King, Steven (Microbiology and Immunology)
Title: NMR STUDIES OF RETROVIRAL NUCLEIC ACID BINKING PROTEINS
Sponsor: NIH - Subcontracts TO University Of Maryland  R01 GM 042561
Project Dates and Amount of Award: 05/01/10-04/30/11; $281,377

PI: *Wobus,Christiane
Title: Mechanism of Norovirus Entry
Sponsor: American Heart Association, Midwest Affiliate
Project Dates and Amount of Award: 07/01/10-06/30/12; $52,000

Molecular & Behavioral Neuroscience Institute

PI: *Burmeister,Margit
Title: A Role for Diaphanous Homolog 3 in the Mammalian Auditory System
Sponsor: NIH  1 F31 DC 011428 01
Project Dates and Amount of Award: 09/01/10-08/31/12; $63,600

PI: *Luma,Jill
Co-I: Cummings, Jennifer (Molecular & Behav Neurosc Inst)
Title: Protective Benefits of Maternal Behavior on Susceptibility for Drug Abuse
Sponsor: NIH  1 R21 DA 027924 01 A1
Project Dates and Amount of Award: 08/01/10-06/30/12; $394,072

PI: *Umemori,Hisashi
Co-I: Sutton, Michael (Molecular & Behav Neurosc Inst)
Title: Excitatory and Inhibitory Synaptogenesis by FGFs and their Role in Epilepsy
Sponsor: NIH  1 R01 NS 070005 01 A1
Project Dates and Amount of Award: 09/01/10-06/30/15; $1,569,695

Molecular & Integrative Physiology

PI: *Pletcher,Scott
Title: Modulation of Lifespan by the Transsulfuration Pathway
Sponsor: Ellison Medical Foundation TO American Federation for Aging Research
Project Dates and Amount of Award: 07/01/10-06/30/11; $50,210

PI: *Schnell,Santiago
Co-I: Macdougald, Ormond (Molec & Integrative Physiology) / Omary, Bishr (Molec & Integrative Physiology)
Title: INTERFACING COMPUTATIONAL AND ENGINEERING WITH DIGESTIVE AND METABOLIC PHYSIOLOGY
Sponsor: NIH  1 R25 DK 088752 01
Project Dates and Amount of Award: 07/01/10-05/31/15; $539,408

MSA Enabling Technologies

PI: *Hanss Jr,Theodore
Title: VOSS: Successful Collaboration between Researchers from Developing and Developed Countries in Virtual Organizations
Sponsor: NSF
Project Dates and Amount of Award: 09/01/10-08/31/13; $282,662

Neurology

PI: *Irani,David
Title: Biomarkers of Acute Multiple Sclerosis
Sponsor: Pfizer Incorporated
Project Dates and Amount of Award: 05/12/10-11/12/10; $9,275

PI: *Paulson,Henry
Title: Targeting Physiologic Changes as a Route Towards Therapy for Degenerative Ataxias
Sponsor: NIH  1 K08 NS 072158 01
Project Dates and Amount of Award: 09/01/10-08/31/15; $848,340

PI: *Segal,Benjamin
Title: Multiple Sclerosis: A Heterogeneous Syndrome
Sponsor: Biogen Idec
Project Dates and Amount of Award: 05/01/10-03/31/11; $51,170

Neurosurgery

PI: *Pandey,Aditya
Title: PAC Large & Giant Aneurysms REGISTRY
Sponsor: Micrus Endovascular Corporation
Project Dates and Amount of Award: 07/02/10-07/31/11; $18,050

Obstetrics & Gynecology

PI: *DeLancey,John
Co-I: Ashton-Miller, James (Mechanical Engineering) / Brandon, Catherine (Radiology Department) / Fenner, Dee (Obstetrics and Gynecology Dept) / Guire, Kenneth (Biostatistics Department)
Title: MECHANISMS OF ANTERIOR VAGINAL WALL SUPPORT FAILURE
Sponsor: NIH  2 R01 HD 038665 11 A1
Project Dates and Amount of Award: 08/16/10-05/31/15; $1,498,829

Ophthalmology & Visual Sciences

PI: *Demb,Jonathan
Title: NMDA Receptor Contributions to Visual Processing in the Mouse
Sponsor: NIH  1 F32 EY 021063 01
Project Dates and Amount of Award: 09/01/10-08/31/12; $98,080

PI: *Gage,Philip
Title: Testing Post-Natal Models of Pitx2-Related Glaucoma
Sponsor: Midwest Eye Banks and Transplantation Center
Project Dates and Amount of Award: 07/01/10-06/30/11; $15,000

PI: *Heckenlively,John
Co-I: Khan, Naheed (Ophthalmology & Visual Science) / Khanna, Hemant (Ophthalmology & Visual Science) / Thompson, Debra (Ophthalmology & Visual Science) / Zacks, David (Ophthalmology & Visual Science)
Title: The Foundation Fighting Blindness (FFB) Research Center for the Study of Retinal Degenerative Diseases at the W.K. Kellogg Eye Center, University of Michigan
Sponsor: Foundation Fighting Blindness
Project Dates and Amount of Award: 07/01/10-06/30/15; $1,810,840

PI: *Hitchcock,Peter
Title: Regulation of Retina-Specific Gene Expression
Sponsor: Midwest Eye Banks and Transplantation Center
Project Dates and Amount of Award: 07/01/10-06/30/11; $15,000

PI: *Hitchcock,Peter
Title: Neuronal Development, Injury and Repair in the Retina
Sponsor: NIH  2 R01 EY 007060 21 A1
Project Dates and Amount of Award: 09/01/10-08/31/15; $2,737,208

PI: *Kahana,Alon
Title: Developing Genomic Technologies to Study Extraocular Muscle Organization and Strabismus Using A Zebrafish Mode
Sponsor: Fight for Sight, Inc.
Project Dates and Amount of Award: 08/01/10-07/31/11; $20,000

PI: *Kahana,Alon
Title: Development and Regeneration of Extraocular Muscles in Zebrafish
Sponsor: Fight for Sight, Inc.
Project Dates and Amount of Award: 06/15/10-08/31/10; $2,100

PI: *Kahana,Alon
Title: The Role of IGF Signaling in Zebrafish Orbital Development and Extraocular Muscle Organization
Sponsor: Knights Templar Eye Foundation
Project Dates and Amount of Award: 07/01/10-06/30/11; $40,000

PI: *Kahana,Alon
Title: Zebrafish and EOM
Sponsor: Midwest Eye Banks and Transplantation Center
Project Dates and Amount of Award: 07/01/10-06/30/11; $2,500

PI: *Mian,Shahzad
Title: Outcomes of Refractive Surgery Performed by Trainees
Sponsor: Midwest Eye Banks and Transplantation Center
Project Dates and Amount of Award: 07/01/10-06/30/11; $2,500

PI: *Petty,Howard
Co-I: Elner, Victor (Ophthalmology & Visual Science)
Title: Novel Immunofluorescence Methods for Retinal Research
Sponsor: NIH  1 R21 EY 019986 01 A1
Project Dates and Amount of Award: 08/05/10-07/31/11; $213,188

PI: *Richards,Julia
Title: Ocular effects of Metformin
Sponsor: NIH  1 R21 EY 021000 01
Project Dates and Amount of Award: 08/01/10-06/30/12; $425,875

PI: *Shtein,Roni
Title: Diagnostic Imaging for Intraoperative Floppy Iris Syndrome
Sponsor: Midwest Eye Banks and Transplantation Center
Project Dates and Amount of Award: 07/01/10-06/30/11; $14,338

PI: *Thompson,Debra
Title: CHROMOPHORE THERAPY IN RETINAL DEGENERATION
Sponsor: Midwest Eye Banks and Transplantation Center
Project Dates and Amount of Award: 07/01/10-06/30/11; $15,000

PI: *Thompson,Debra
Title: MERTK Signaling Pathways in RPE Phagocytosis
Sponsor: Midwest Eye Banks and Transplantation Center
Project Dates and Amount of Award: 07/01/10-06/30/11; $2,500

PI: *Wong,Kwoon
Title: 2010 RPB CAREER-DEVELOPMENT AWARD
Sponsor: Research To Prevent Blindness
Project Dates and Amount of Award: 07/01/10-06/30/14; $200,000

PI: *Zacks,David
Title: Effect of Chemokine Interleukin-8 and its Receptor CXCR2 on Glial Cell Activation in the Retina in an Animal Model of Choroidal Neovascularization
Sponsor: Midwest Eye Banks and Transplantation Center
Project Dates and Amount of Award: 07/01/10-06/30/11; $2,500

PI: *Zacks,David
Title: AUTOPHAGY AND CONTROL OF PHOTORECEPTOR APOPTOSIS
Sponsor: NIH  1 R01 EY 02823 01
Project Dates and Amount of Award: 09/01/10-07/31/15; $1,875,072

Orthopaedic Surgery

PI: *Miller,Bruce
Title: Sports Medicine and Shoulder Surgery Fellowship
Sponsor: DePuy Mitek, Inc
Project Dates and Amount of Award: 08/01/10-07/31/11; $25,000

PI: *Wojtys,Edward
Co-I: Ashton-Miller, James (Mechanical Engineering) / Guire, Kenneth (Biostatistics Department)
Title: EFFECT OF 3-D COMPOUND IMPULSIVE LOADING ON RELATIVE ACL STRAIN
Sponsor: NIH  2 R01 AR 054821 04
Project Dates and Amount of Award: 08/19/10-06/30/13; $809,883

Otolaryngology

PI: *Arts,H
Title: Otonomy - Single Intratympanic Injection in Subjects with Unilateral Meniere's Disease
Sponsor: Otonomy, Inc
Project Dates and Amount of Award: 08/01/10-07/31/11; $53,150

PI: *King,William
Title: Vestibular Control of Head Movements in Guinea Pig
Sponsor: NIH  1 F31 DC 010947 01 A1
Project Dates and Amount of Award: 09/01/10-08/31/11; $31,166

PI: *Zwolan,Teresa
Title: Clinical Evaluation of the Nucleus 5 Cochlear Implant System
Sponsor: Cochlear Corporation
Project Dates and Amount of Award: 08/01/10-07/31/13; $42,454

Pathology

PI: *Bhagavathula,Narasimharao
Title: RESEARCH PROPOSAL FOR EVALUATING TWO COMPOUNDS IN THE HUMAN SKIN - SCID MOUSE TRANSPLANT MODEL
Sponsor: JV Biolabs
Project Dates and Amount of Award: 08/05/10-08/31/11; $145,935

PI: *Chinnaiyan,Arul
Title: THE ROLE OF MICRORNA MIR-101 IN PROSTATE CANCER PROGRESSION
Sponsor: US DOD-Army, Department of the
Project Dates and Amount of Award: 09/01/10-09/30/12; $123,921

PI: *Chinnaiyan,Arul
Co-I: Prensner, John (Ctr fr Translational Pathology)
Title: THE ROLE OF SOX4 IN PROSTATE CANCER METASTASES
Sponsor: US DOD-Army, Department of the
Project Dates and Amount of Award: 09/01/10-09/30/12; $98,091

PI: *Dou,Yali
Title: Targeting MLL in Acute Myeloid Leukemia
Sponsor: Amer Assoc for Cancer Research
Project Dates and Amount of Award: 09/01/10-08/31/11; $50,000

PI: *Duckett,Colin
Co-I: Edwards, Chris (Cell and Developmental Biology) / Elenitoba-Johnson, Kojo (Pathology Department) / Lim, Megan (Pathology Department)
Title: SIGNAL TRANSDUCTION PATHWAYS IN CD30-POSITIVE LYMPHOMAS
Sponsor: NIH  1 R01 CA 142809 01 A1
Project Dates and Amount of Award: 07/12/10-12/31/14; $1,415,635

PI: *Elenitoba-Johnson,Kojo
Co-I: Basrur, Venkatesha (Pathology Department)
Title: RECHARGE:  Protein ID by LTQ-Oribtrap XL
Sponsor: NIH - Subcontracts TO Cornell University
Project Dates and Amount of Award: 04/27/10-09/30/10; $10,026

PI: *Elenitoba-Johnson,Kojo
Co-I: Basrur, Venkatesha (Pathology Department)
Title: RECHARGE:  Protein ID by LTQ-Oribtrap XL
Sponsor: NIH - Subcontracts TO University of Toledo
Project Dates and Amount of Award: 05/05/10-09/30/10; $418

PI: *Elenitoba-Johnson,Kojo
Co-I: Basrur, Venkatesha (Pathology Department)
Title: RECHARGE: Protein ID by LTQ-Oribtrap XL
Sponsor: University of Toledo
Project Dates and Amount of Award: 04/19/10-06/30/11; $279

PI: *Franchi,Luigi
Title: Role of the Inflammasome in Models of Colitis
Sponsor: Crohn's and Colitis Foundation
Project Dates and Amount of Award: 07/01/10-06/30/13; $267,764

PI: *Hogaboam,Cory
Title: Role of IL-25 and IL-33/ST2 in Experimental Fungal Asthma
Sponsor: Centocor, Inc.
Project Dates and Amount of Award: 08/01/10-07/31/11; $262,203

PI: *Jentzen,Jeffrey
Title: FY09 Coverdell Forensic Science Improvement Grants Program
Sponsor: SubK-DoJ-US TO Washtenaw County
Project Dates and Amount of Award: 10/01/09-12/31/10; $36,500

PI: *Liu,Yifan
Title: POLYCOMB-MEDIATED HETEROCHROMATIN FORMATION IN TETRAHYMENA
Sponsor: NIH  1 R01 GM 087343 01 A2
Project Dates and Amount of Award: 08/01/10-07/31/15; $1,465,138

PI: *Lukacs,Nicholas
Co-I: Duckett, Colin (Pathology Department) / Hogaboam, Cory (Pathology Department)
Title: ROLE OF SCF IN AIRWAY EOSINOPHIL INFLAMMATION
Sponsor: NIH  2 R01 HL 059178 09 A2
Project Dates and Amount of Award: 07/12/10-04/30/14; $1,540,858

PI: *Nunez,Gabriel
Title: ROLE OF MAST CELLS IN NLRP3-MEDIATED SKIN INFLAMMATION
Sponsor: NIH  1 R01 AR 059688 01
Project Dates and Amount of Award: 07/10/10-06/30/15; $1,747,125

PI: *Ward,Peter
Co-I: Sarma, J (Pathology Department) / Zetoune, Firas (Pathology Department)
Title: PROTECTIVE EFFECTS ONF ANTI-C51 IN SEPSIS
Sponsor: NIH  2 R01 GM 061656 09
Project Dates and Amount of Award: 09/01/10-08/31/14; $1,248,716

Pediatrics & Communicable Diseases

PI: *Armstrong,Aimee
Title: Melody Transcatheter Pulmonary Valve Post-Approval Study
Sponsor: Medtronic, Inc.
Project Dates and Amount of Award: 07/19/10-07/31/15; $42,200

PI: *Barks,John
Co-I: Joshi, Sucheta (Pediatrics-Neurology)
Title: Prophylactic Phenobarbital after Resolution of Neonatal Seizures
Sponsor: NIH - Subcontracts TO University of Rochester  R01 HD 057977
Project Dates and Amount of Award: 07/01/10-06/30/11; $349,453

PI: *Castle,Valerie
Title: Normal and Neoplastic Stem Cell Niches in the Hematopoietic System
Sponsor: NIH - Subcontracts TO Yale University  K12 HD 000850
Project Dates and Amount of Award: 07/01/10-08/31/10; $19,125

PI: *Dempsey,Amanda / Mendez,David
Co-I: Riolo, Rick (LSA Study of Complex Systems)
Title: School Mandates for Human Papillomavirus Vaccination: Use of an Agent-Based Model
Sponsor: NIH  1 R21 HD 062929 01 A1
Project Dates and Amount of Award: 08/11/10-07/31/12; $382,435

PI: *Hildebrandt,Friedhelm
Co-I: Airik, Rannar (Pediatrics-Nephrology) / Otto, Edgar (Pediatrics-Nephrology) / Zhou, Weibin (Pediatrics-Nephrology)
Title: NEW GENES AND PATHOMECHANISMS OF CONGENITAL ABNORMALITIES OF THE KIDNEY (CAKUT)
Sponsor: NIH  1 R01 DK 088767 01
Project Dates and Amount of Award: 07/05/10-06/30/14; $1,338,821

PI: *Keegan,Catherine
Title: MOUSE MODELS OF GENOMIC INSTABILITY AND BIRTH DEFECTS
Sponsor: NIH  3 R01 HD 058606 02 S1
Project Dates and Amount of Award: 07/20/10-06/30/11; $157,528

PI: *Nasr,Samya
Title: Cystic Fibrosis Center Grant 2010-2011
Sponsor: Cystic Fibrosis Foundation
Project Dates and Amount of Award: 07/01/10-06/30/11; $189,200

PI: *Schiller,Jocelyn
Title: Parental Assessment of Medical Students' E-Mails
Sponsor: Council on Medical Student Education in Pediatrics (COMSEP)
Project Dates and Amount of Award: 04/01/10-03/31/11; $2,500

PI: *Shavit,Jordan
Title: Determinining Modifier Genes of PROC Deficiency
Sponsor: American Society of Hematology
Project Dates and Amount of Award: 06/01/10-09/01/10; $4,000

PI: *Vazquez,Delia / Padmanabhan,Vasantha
Title: DEVELOPMENT ORIGINS OF ENDOCRINE DYSFUNCTIONS
Sponsor: NIH  2 T32 DK 071212 06
Project Dates and Amount of Award: 07/01/10-06/30/15; $1,279,895

Pharmacology

PI: *Beg,Asim
Title: Alfred P. Sloan Research Fellowship for Dr. Asim Beg Neuroscience
Sponsor: Sloan, Alfred P., Foundation
Project Dates and Amount of Award: 09/15/10-09/15/12; $50,000

Physical Medicine & Rehabilitation

PI: *Gordon,Paul
Title: The Metabolic Cost of Recumbent Exercise at Self Selected and Specifiied Intensity in Overweight Individuals
Sponsor: NuStep, Inc
Project Dates and Amount of Award: 07/14/10-03/31/11; $63,660

PI: *Hurvitz,Edward
Co-I: Ashton-Miller, James (Mechanical Engineering) / Eckner, James () / Richardson, James (Physical Medicine & Rehab Dept)
Title: THE ROLE OF BECK STRENGTH AND REACTION TIME ON PROTECTIVE HEAD MANEUVERS AND BRACING: EFFECT OF AGE AND GENDER
Sponsor: NIH  TO University of Pittsburgh  K12
Project Dates and Amount of Award: 07/01/10-08/31/10; $116,100

PI: *Murphy,Susan
Co-I: Hurvitz, Edward (Physical Medicine & Rehab Dept) / Kalpakjian, Claire (Physical Medicine & Rehab Dept)
Title: Assessing Real-World Impact of Clinical Interventions and Outcomes: The Science of Ambulatory Assessment
Sponsor: NIH  1 R13 HD 066812 01
Project Dates and Amount of Award: 09/01/10-08/31/11; $15,000

Psychiatry

PI: *Blow,Frederic
Co-I: Barry, Kristen (Psychiatry Department) / Chermack, Stephen (Psychiatry Department) / Cunningham, Rebecca (Emergency Medicine UM Adult) / Ilgen, Mark (Psychiatry Department) / Walton, Maureen (Psychiatry Department)
Title: OPTIMIZING ALCOHOL BRIEF INTERVENTIONS IN THE ED: COMPUTER VS. THERAPIST DELIVERY
Sponsor: NIH  1 R01 AA 018659 01 A1
Project Dates and Amount of Award: 07/20/10-06/30/15; $3,711,918

PI: *Deldin,Patricia
Co-I: Greden, John (Psychiatry Department)
Title: Developing a Sustainable Consumer Clearinghouse for Translational Depression and Bipolar Disorder Research
Sponsor: NIH  1 RC4 MH 091975 01
Project Dates and Amount of Award: 07/15/10-06/14/13; $905,298

PI: *Kales,Helen
Co-I: Blow, Frederic (Psychiatry Department)
Title: PERSONALIZED ANTIDEPRESSANT ADHERENCE STRATEGIES FOR DEPRESSED ELDERS
Sponsor: NIH  1 R01 MH 087557 01 A1
Project Dates and Amount of Award: 08/10/10-07/31/15; $1,537,427

PI: *Robinson,Elizabeth
Title: RECOVERY: VARIETIES AND DIMENSIONS
Sponsor: NIH  1 R21 AA 019723 01
Project Dates and Amount of Award: 07/20/10-06/30/12; $426,625

Radiation Oncology

PI: *Cao,Yue
Co-I: Chenevert, Thomas (Radiology Department) / Frey, Kirk (Radiology Department) / Hussain, Hero (Radiology Department) / Johnson, Timothy (Biostatistics Department) / Lawrence, Theodore (Radiation Oncology - Ann Arbor) / Pan, Charlie (Radiation Oncology - Ann Arbor) / Ten Haken, Randall (Radiation Oncology - Ann Arbor)
Title: PREDICTING RADIATION LIVER INJURY USING MRI PERFUSION
Sponsor: NIH  1 R01 CA 132834 01 A1
Project Dates and Amount of Award: 08/01/10-05/31/15; $1,885,293

PI: *Kong,Fengming
Co-I: Arenberg, Douglas (Int Med-Pulm./Critical Care) / Cao, Yue (Radiation Oncology - Ann Arbor) / Frey, Kirk (Radiology Department) / Hayman, James (Radiation Oncology - Ann Arbor) / Kessler, Marc (Radiation Oncology - Ann Arbor) / Lawrence, Theodore (Radiation Oncology - Ann Arbor) / Normolle, Daniel (Radiation Oncology - Ann Arbor) / Orringer, Mark (Thoracic Surgery Section) / Pan, Charlie (Radiation Oncology - Ann Arbor) / Piert, Morand (Radiology Department) / Quint, Leslie (Radiology Department) / Ten Haken, Randall (Radiation Oncology - Ann Arbor)
Title: FUNCTIONAL IMAGE AND MOLECULAR MARKER TO INDIVIDUALIZE ADAPTIVE RADIATION DOSE ESCALATION IN PATIENTS WITH NON-SMALL CELL LUNG CANCER
Sponsor: NIH  1 R01 CA 142840 01
Project Dates and Amount of Award: 07/01/10-04/30/15; $2,251,487

PI: *Rehemtulla,Alnawaz
Title: Characterization of Anti-Neoplastic FADD Kinase Inhibitors Identified Utilizing a Molecular Imaging-Based High Throughput Screen
Sponsor: Radiological Society of North America
Project Dates and Amount of Award: 07/01/10-06/30/11; $30,000

Radiology

PI: *Carson,Paul
Co-I: Kripfgans, Oliver (Radiology Department)
Title: NOVEL ELECTROMAGNETIC-ULTRASOUND SYNERGISTIC TECHNIQUE FOR TREATMENT OF CANCER
Sponsor: US DOD-Army, Department of the
Project Dates and Amount of Award: 06/30/10-09/30/12; $338,976

PI: *Hadjiyski,Lubomir
Co-I: Caoili, Elaine (Radiology Department) / Chan, Heang-Ping (Radiology Department) / Cohan, Richard (Radiology Department) / Montie, James (Urology Surgery) / Sahiner, Berkman (Radiology Department) / Shah, Rajal (Pathology Department) / Weizer, Alon (Urology Surgery)
Title: COMPUTER-AIDED DETECTION OF URINARY TRACT CANCER ON MDCT UROGRAPHY
Sponsor: NIH  1 R01 CA 134688 01 A2
Project Dates and Amount of Award: 08/02/10-05/31/15; $1,666,074

Surgery

PI: *Bolling,Steven
Title: Comparison of Analysis Methods for Tart Cherry Paste
Sponsor: Cherry Capital Services, Inc/FruitFast
Project Dates and Amount of Award: 08/15/10-02/15/11; $3,631

PI: *Chung,Kevin
Co-I: Song, Jae (Plastic Surgery Section)
Title: AN OUTCOME STUDY FOR ULNAR NEUROPATHY AT THE ELBOW
Sponsor: NIH  1 F32 AR 058105 01
Project Dates and Amount of Award: 08/05/10-08/04/12; $107,128

PI: *Englesbe,Michael
Title: Sarcopenia and Waitlist Mortality in Liver Transplant Candidates
Sponsor: American Society of Transplant Surgeons (ASTS)
Project Dates and Amount of Award: 05/31/10-08/06/10; $3,500

PI: *Liu,Yang
Title: Checkpoints of Host Response to Cellular Injuries
Sponsor: NIH  3 R01 AI 064350 04 S1
Project Dates and Amount of Award: 07/19/10-07/18/11; $231,149

PI: *Magee,John
Title: Childhood Liver Disease Research and Education Network Data Coordinating Center
Sponsor: NIH  3 U01 DK 062456 09 S1
Project Dates and Amount of Award: 08/10/10-07/31/11; $399,611

PI: *Patel,Himanshu
Co-I: Upchurch Jr, Gilbert (Vascular Surgery Section) / Williams, David (Department of Radiology)
Title: Evaluation of the Clinical Performance of the Valiant Thoracic Stent Graft with Captivia Delivery System for the Treatment of Acute, Complicated Type B Aortic Dissections
Sponsor: Medtronic Vascular, Inc
Project Dates and Amount of Award: 05/27/10-12/31/16; $134,600

PI: *Patel,Himanshu
Co-I: Upchurch Jr, Gilbert (Vascular Surgery Section) / Williams, David (Department of Radiology)
Title: RESCUE
Sponsor: Medtronic Vascular, Inc
Project Dates and Amount of Award: 06/10/10-12/30/16; $108,200

PI: *Teitelbaum,Daniel
Title: Evalution of Lipid Emulsions
Sponsor: Baxter Healthcare Corporation
Project Dates and Amount of Award: 08/02/10-08/02/11; $377,331

PI: *Welling Iii,Theodore
Title: HUMAN HEPATOCELLULAR CARCINOMA AND THE MICROENVIRONMENTAL IMMUNOSUPPRESSIVE NETWORK
Sponsor: Society of University Surgeons
Project Dates and Amount of Award: 07/01/10-06/30/11; $30,000

Unit for Laboratory Animal Medicine

PI: *Nemzek,Jean
Title: Immunological Impact of Buprenorphine Analgesia on a Model of Sepsis: Influences of Strain, Sex and Disease Severity
Sponsor: American College of Laboratory Animal Medicine Foundation (ACLAM)
Project Dates and Amount of Award: 07/01/10-06/30/11; $30,000

Urology

PI: *Kasina,Sathish
Title: CXCL12/CXCR4 Axis Promotion of BPH in the Aging Prostate
Sponsor: Ellison Medical Foundation TO American Federation for Aging Research
Project Dates and Amount of Award: 07/01/10-06/30/11; $51,854

PI: *Roberts,William
Co-I: Cain, Charles (Biomedical Engineering) / Fowlkes, J (Radiology Department)
Title: HISTOTRIPSY TISSUE INTERACTIONS FOR BPH THERAPY
Sponsor: NIH  1 R01 DK 087871 01
Project Dates and Amount of Award: 08/01/10-06/30/15; $1,664,019


UMMS RESEARCH PUBLICATIONS

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Books – Chapters or Volumes of Books – Contributions to Books

Pediatrics & Communicable Diseases

Borregaard N and Boxer LA.  Disorders of neutrophil function.   In Hematology 8th edition.  Kaushansky K, Lichtman MA, Bentler E, Kipps T, Seligsohn V, Prchal JT (eds). New York, McGraw-Hill, pp 951-986.

Journal Articles

Anesthesiology

Clauw Daniel J. Pain management: Fibromyalgia drugs are 'as good as it gets' in chronic pain. Nature reviews. Rheumatology. 2010 Aug. 6(8): 439-40. PMID# 20676122

Green Carmen R, Hart-Johnson Tamera. The adequacy of chronic pain management prior to presenting at a tertiary care pain center: the role of patient socio-demographic characteristics. The journal of pain : official journal of the American Pain Society. 2010 Aug. 11(8): 746-54. PMID# 20399710

Nafiu Olubukola O, Burke Constance, Lee Joyce, Voepel-Lewis Terri, Malviya Shobha, Tremper Kevin K. Neck circumference as a screening measure for identifying children with high body mass index. Pediatrics. 2010 Aug. 126(2): e306-10. PMID# 20603254

Napadow Vitaly, Lacount Lauren, Park Kyungmo, As-Sanie Sawsan, Clauw Daniel J, Harris Richard E. Intrinsic brain connectivity in fibromyalgia is associated with chronic pain intensity. Arthritis and rheumatism. 2010 Aug. 62(8): 2545-55. PMID# 20506181

Xu Jiadi, Soong Ronald, Im Sang-Choul, Waskell Lucy, Ramamoorthy Ayyalusamy. INEPT-based separated-local-field NMR spectroscopy: a unique approach to elucidate side-chain dynamics of membrane-associated proteins. Journal of the American Chemical Society. 2010 Jul 28. 132(29): 9944-7. PMID# 20593897

Tait Alan R, Voepel-Lewis Terri, Zikmund-Fisher Brian J, Fagerlin Angela. The effect of format on parents' understanding of the risks and benefits of clinical research: a comparison between text, tables, and graphics. Journal of health communication. 2010 Jul. 15(5): 487-501. PMID# 20677054

Williams Arthur, Hagerty Bonnie M, Brasington Steve J, Clem Joseph B, Williams David A. Stress Gym: Feasibility of deploying a web-enhanced behavioral self-management program for stress in a military setting. Military medicine. 2010 Jul. 175(7): 487-93. PMID# 20684452

Clauw Daniel J. Perspectives on fatigue from the study of chronic fatigue syndrome and related conditions. PM&R : the journal of injury, function, and rehabilitation. 2010 May. 2(5): 414-30. PMID# 20656623

Biological Chemistry

Li Xianghui, Telser Joshua, Kunz Ryan C, Hoffman Brian M, Gerfen Gary, Ragsdale Stephen W. Observation of organometallic and radical intermediates formed during the reaction of methyl-coenzyme M reductase with bromoethanesulfonate. Biochemistry. 2010 Aug 17. 49(32): 6866-76. PMID# 20597483

Khare Dheeraj, Wang Bo, Gu Liangcai, Razelun Jamie, Sherman David H, Gerwick William H, Håkansson Kristina, Smith Janet L. Conformational switch triggered by {alpha}-ketoglutarate in a halogenase of curacin A biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 2010 Aug 10. 107(32): 14099-104. PMID# 20660778

Purcell Erin B, McDonald Claudia A, Palfey Bruce A, Crosson Sean. An analysis of the solution structure and signaling mechanism of LovK, a sensor histidine kinase integrating light and redox signals. Biochemistry. 2010 Aug 10. 49(31): 6761-70. PMID# 20593779

Klionsky Daniel J. The autophagy connection. Developmental cell. 2010 Jul 20. 19(1): 11-2. PMID# 20643346

Cell & Developmental Biology

Sun Xiankui, Fontaine Jean-Marc, Hoppe Adam D, Carra Serena, DeGuzman Cheryl, Martin Jody L, Simon Stephanie, Vicart Patrick, Welsh Michael J, Landry Jacques, Benndorf Rainer. Abnormal interaction of motor neuropathy-associated mutant HspB8 (Hsp22) forms with the RNA helicase Ddx20 (gemin3). Cell stress&chaperones. 2010 Sep. 15(5): 567-82. PMID# 20157854

Gurda Grzegorz T, Crozier Stephen J, Ji Baoan, Ernst Stephen A, Logsdon Craig D, Rothermel Beverly A, Williams John A. Regulator of calcineurin 1 controls growth plasticity of adult pancreas. Gastroenterology. 2010 Aug. 139(2): 609-19, 619.e1-6. PMID# 20438729

Schoen Cynthia J, Emery Sarah B, Thorne Marc C, Ammana Hima R, Sliwerska Elzbieta, Arnett Jameson, Hortsch Michael, Hannan Frances, Burmeister Margit, Lesperance Marci M. Increased activity of Diaphanous homolog 3 (DIAPH3)/diaphanous causes hearing defects in humans with auditory neuropathy and in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 2010 Jul 27. 107(30): 13396-401. PMID# 20624953

Center for Behavioral and Decision Sciences in Medicine

Lewis Carmen L, Couper Mick P, Levin Carrie A, Pignone Michael P, Zikmund-Fisher Brian J. Plans to stop cancer screening tests among adults who recently considered screening. Journal of general internal medicine. 2010 Aug. 25(8): 859-64. PMID# 20407841

Tait Alan R, Voepel-Lewis Terri, Zikmund-Fisher Brian J, Fagerlin Angela. The effect of format on parents' understanding of the risks and benefits of clinical research: a comparison between text, tables, and graphics. Journal of health communication. 2010 Jul. 15(5): 487-501. PMID# 20677054

Center for Computational Medicine and Bioinformatics

Cobey Sarah, Pascual Mercedes, Dieckmann Ulf. Ecological factors driving the long-term evolution of influenza's host range. Proceedings. Biological sciences / The Royal Society. 2010 Sep 22. 277(1695): 2803-10. PMID# 20444714

Emergency Medicine

Walton Maureen A, Chermack Stephen T, Shope Jean T, Bingham C Raymond, Zimmerman Marc A, Blow Frederic C, Cunningham Rebecca M. Effects of a brief intervention for reducing violence and alcohol misuse among adolescents: a randomized controlled trial. JAMA : the journal of the American Medical Association. 2010 Aug 4. 304(5): 527-35. PMID# 20682932

Ding Ru, McCarthy Melissa L, Desmond Jeffrey S, Lee Jennifer S, Aronsky Dominik, Zeger Scott L. Characterizing waiting room time, treatment time, and boarding time in the emergency department using quantile regression. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine. 2010 Aug. 17(8): 813-23. PMID# 20670318

Frye Victoria, Koblin Beryl, Chin John, Beard John, Blaney Shannon, Halkitis Perry, Vlahov David, Galea Sandro. Neighborhood-level correlates of consistent condom use among men who have sex with men: a multi-level analysis. AIDS and behavior. 2010 Aug. 14(4): 974-85. PMID# 18712593

Bohnert Amy S B, Prescott Marta R, Vlahov David, Tardiff Kenneth J, Galea Sandro. Ambient temperature and risk of death from accidental drug overdose in New York City, 1990-2006. Addiction (Abingdon, England). 2010 Jun. 105(6): 1049-54. PMID# 20219056

Family Medicine

Joseph C L M, Havstad S L, Johnson D, Saltzgaber J, Peterson E L, Resnicow K, Ownby D R, Baptist A P, Johnson C C, Strecher V J. Factors associated with nonresponse to a computer-tailored asthma management program for urban adolescents with asthma. The Journal of asthma : official journal of the Association for the Care of Asthma. 2010 Aug. 47(6): 667-73. PMID# 20642376

Human Genetics

Jankovic Ivana, Vonholdt Bridgett M, Rosenberg Noah A. Heterozygosity of the Yellowstone wolves. Molecular ecology. 2010 Aug. 19(16): 3246-9. PMID# 20670367

Institute of Gerontology

Hsu Yvonne, Chen Luyun, Tumbarello Julie, Ashton-Miller James A, DeLancey John O L. In vivo assessment of anterior compartment compliance and its relation to prolapse. International urogynecology journal and pelvic floor dysfunction. 2010 Sep. 21(9): 1111-5. PMID# 20440477

Larson Kindra A, Hsu Yvonne, Chen Luyun, Ashton-Miller James A, DeLancey John O L. Magnetic resonance imaging-based three-dimensional model of anterior vaginal wall position at rest and maximal strain in women with and without prolapse. International urogynecology journal and pelvic floor dysfunction. 2010 Sep. 21(9): 1103-9. PMID# 20449568

Saint Sanjay, Kowalski Christine P, Banaszak-Holl Jane, Forman Jane, Damschroder Laura, Krein Sarah L. The importance of leadership in preventing healthcare-associated infection: results of a multisite qualitative study. Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America. 2010 Sep. 31(9): 901-7. PMID# 20658939

Internal Medicine – Cardiovascular Medicine

Brook Robert D, Rajagopalan Sanjay. Particulate matter air pollution and atherosclerosis. Current atherosclerosis reports. 2010 Sep. 12(5): 291-300. PMID# 20617466

Russo Hana M, Wickenheiser Kevin J, Luo Wei, Ohman Miina K, Franchi Luigi, Wright Andrew P, Bodary Peter F, Gabriel Núñez, Eitzman Daniel T. P-selectin glycoprotein ligand-1 regulates adhesive properties of the endothelium and leukocyte trafficking into adipose tissue. Circulation research. 2010 Aug 6. 107(3): 388-97. PMID# 20558823

Booher Anna M, Bach David S. Acquired pulmonary vein stenosis: one problem, two mechanisms. Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography. 2010 Aug. 23(8): 904.e1-3. PMID# 20138470

Duvernoy Claire S, Yeo Adeline A, Wong Mayme, Cox David A, Kim Hyungjin M. Antiplatelet therapy use and the risk of venous thromboembolic events in the Raloxifene Use for the Heart (RUTH) trial. Journal of women's health (2002). 2010 Aug. 19(8): 1459-65. PMID# 20626269

Herron Todd J, Milstein Michelle L, Anumonwo Justus, Priori Silvia G, Jalife José. Purkinje cell calcium dysregulation is the cellular mechanism that underlies catecholaminergic polymorphic ventricular tachycardia. Heart rhythm : the official journal of the Heart Rhythm Society. 2010 Aug. 7(8): 1122-8. PMID# 20538074

Hiratzka Loren F, Bakris George L, Beckman Joshua A, Bersin Robert M, Carr Vincent F, Casey Donald E, Eagle Kim A, Hermann Luke K, Isselbacher Eric M, Kazerooni Ella A, Kouchoukos Nicholas T, Lytle Bruce W, Milewicz Dianna M, Reich David L, Sen Souvik, Sh Special Article: 2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM Guidelines for the diagnosis and management of patients with thoracic aortic disease: Executive summary: A report of the American College of Cardiology Foundation/American Heart Association Anesthesia and analgesia. 2010 Aug. 111(2): 279-315. PMID# 20664093

Popescu Ioana, Nallamothu Brahmajee K, Vaughan-Sarrazin Mary S, Cram Peter. Racial differences in admissions to high-quality hospitals for coronary heart disease. Archives of internal medicine. 2010 Jul 26. 170(14): 1209-15. PMID# 20660838

Chae Sanders H, Koelling Todd M. Patient and physician determinants of implantable cardioverter defibrillator use in the heart failure population. Congestive heart failure (Greenwich, Conn.). 2010 Jul. 16(4): 141-6. PMID# 20662865

Eagle Kim A, Taubman A Alfred. Sophomore season on the Laxa i'Adolol: a trout fisherman's search for Atlantic salmon. Methodist DeBakey cardiovascular journal. 2010 Apr-Jun. 6(2): 27-30. PMID# 20661190

Internal Medicine – Gastroenterology

Pausawasdi Nonthalee, Scheiman James M. Pancreatic cystic lesions. Current opinion in gastroenterology. 2010 Sep. 26(5): 506-12. PMID# 20625288

Camilleri M, Thorne N K, Ringel Y, Hasler W L, Kuo B, Esfandyari T, Gupta A, Scott S M, McCallum R W, Parkman H P, Soffer E, Wilding G E, Semler J R, Rao S S C. Wireless pH-motility capsule for colonic transit: prospective comparison with radiopaque markers in chronic constipation. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2010 Aug. 22(8): 874-82, e233. PMID# 20465593

DiMagno Matthew J, Lee Sae-Hong, Owyang Chung, Zhou Shi-yi. Inhibition of acinar apoptosis occurs during acute pancreatitis in the human homologue DeltaF508 cystic fibrosis mouse. American journal of physiology. Gastrointestinal and liver physiology. 2010 Aug. 299(2): G400-12. PMID# 20522641

Fontana Robert J, Seeff Leonard B, Andrade Raúl J, Björnsson Einar, Day Christopher P, Serrano Jose, Hoofnagle Jay H. Standardization of nomenclature and causality assessment in drug-induced liver injury: summary of a clinical research workshop. Hepatology (Baltimore, Md.). 2010 Aug. 52(2): 730-42. PMID# 20564754

Khan Asra S, Hussain Hero K, Johnson Timothy D, Weadock William J, Pelletier Shawn J, Marrero Jorge A. Value of delayed hypointensity and delayed enhancing rim in magnetic resonance imaging diagnosis of small hepatocellular carcinoma in the cirrhotic liver. Journal of magnetic resonance imaging : JMRI. 2010 Aug. 32(2): 360-6. PMID# 20677263

Lok Anna S F. Drug therapy: tenofovir. Hepatology (Baltimore, Md.). 2010 Aug. 52(2): 743-7. PMID# 20597070

Wang Thomas D. Targeted imaging of flat and depressed colonic neoplasms. Gastrointestinal endoscopy clinics of North America. 2010 Jul. 20(3): 579-83. PMID# 20656254

Internal Medicine – General Medicine

Meddings Jennifer, Rogers Mary A M, Macy Michelle, Saint Sanjay. Systematic review and meta-analysis: reminder systems to reduce catheter-associated urinary tract infections and urinary catheter use in hospitalized patients. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2010 Sep 1. 51(5): 550-60. PMID# 20673003

Saint Sanjay, Kowalski Christine P, Banaszak-Holl Jane, Forman Jane, Damschroder Laura, Krein Sarah L. The importance of leadership in preventing healthcare-associated infection: results of a multisite qualitative study. Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America. 2010 Sep. 31(9): 901-7. PMID# 20658939

Hollingsworth John M, Zhang Yun, Krein Sarah L, Ye Zaojun, Hollenbeck Brent K. Understanding the variation in treatment intensity among patients with early stage bladder cancer. Cancer. 2010 Aug 1. 116(15): 3587-94. PMID# 20564128

Schuster Nathaniel M, Rogers Mary A M, McMahon Laurence M. Using search engine query data to track pharmaceutical utilization: a study of statins. The American journal of managed care. 2010 Aug. 16(8): e215-9. PMID# 20690788

Tait Alan R, Voepel-Lewis Terri, Zikmund-Fisher Brian J, Fagerlin Angela. The effect of format on parents' understanding of the risks and benefits of clinical research: a comparison between text, tables, and graphics. Journal of health communication. 2010 Jul. 15(5): 487-501. PMID# 20677054

Zivin Kara, Ratliff Scott, Heisler Michele M, Langa Kenneth M, Piette John D. Factors influencing cost-related nonadherence to medication in older adults: a conceptually based approach. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research. 2010 Jun-Jul. 13(4): 338-45. PMID# 20070641

Ching Tsui-Ting, Paal Alisha B, Mehta Avni, Zhong Linda, Hsu Ao-Lin. drr-2 encodes an eIF4H that acts downstream of TOR in diet-restriction-induced longevity of C. elegans. Aging cell. 2010 Aug. 9(4): 545-57. PMID# 20456299

Patterson Jan E, Malani Preeti N, Maragakis Lisa L. Infection control in the intensive care unit: progress and challenges in systems and accountability. Critical care medicine. 2010 Aug. 38(8 Suppl): S265-8. PMID# 20647783

Internal Medicine – Hematology and Oncology

Yamashita Junro, McCauley Laurie K, Van Poznak Catherine. Updates on osteonecrosis of the jaw. Current opinion in supportive and palliative care. 2010 Sep. 4(3): 200-6. PMID# 20657284

Richardson Paul G, Weller Edie, Lonial Sagar, Jakubowiak Andrzej J, Jagannath Sundar, Raje Noopur S, Avigan David E, Xie Wanling, Ghobrial Irene M, Schlossman Robert L, Mazumder Amitabha, Munshi Nikhil C, Vesole David H, Joyce Robin, Kaufman Jonathan L, D Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma. Blood. 2010 Aug 5. 116(5): 679-86. PMID# 20385792

Henry N L, Pchejetski D, A'Hern R, Nguyen A T, Charles P, Waxman J, Li L, Storniolo A M, Hayes D F, Flockhart D A, Stearns V, Stebbing J. Inflammatory cytokines and aromatase inhibitor-associated musculoskeletal syndrome: a case-control study. British journal of cancer. 2010 Jul 27. 103(3): 291-6. PMID# 20606683

Karatas Hacer, Townsend Elizabeth C, Bernard Denzil, Dou Yali, Wang Shaomeng. Analysis of the binding of mixed lineage leukemia 1 (MLL1) and histone 3 peptides to WD repeat domain 5 (WDR5) for the design of inhibitors of the MLL1-WDR5 interaction. Journal of medicinal chemistry. 2010 Jul 22. 53(14): 5179-85. PMID# 20575550

Magenau John M, Qin Xuemei, Tawara Isao, Rogers Clare E, Kitko Carrie, Schlough Matthew, Bickley Daniel, Braun Thomas M, Jang Pil-Sang, Lowler Kathleen P, Jones Dawn M, Choi Sung W, Reddy Pavan, Mineishi Shin, Levine John E, Ferrara James L M, Paczesny So Frequency of CD4(+)CD25(hi)FOXP3(+) regulatory T cells has diagnostic and prognostic value as a biomarker for acute graft-versus-host-disease. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 2010 Jul. 16(7): 907-14. PMID# 20302964

Internal Medicine – Infectious Diseases

Yeh Norman, Glosson Nicole L, Wang Nan, Guindon Lynette, McKinley Carl, Hamada Hiromasa, Li Qingsheng, Dutton Richard W, Shrikant Protul, Zhou Baohua, Brutkiewicz Randy R, Blum Janice S, Kaplan Mark H. Tc17 cells are capable of mediating immunity to vaccinia virus by acquisition of a cytotoxic phenotype. Journal of immunology (Baltimore, Md. : 1950). 2010 Aug 15. 185(4): 2089-98. PMID# 20624947

Gandhi Tejal N, DePestel Daryl D, Collins Curtis D, Nagel Jerod, Washer Laraine L. Managing antimicrobial resistance in intensive care units. Critical care medicine. 2010 Aug. 38(8 Suppl): S315-23. PMID# 20647789

Shuman Emily K, Chenoweth Carol E. Recognition and prevention of healthcare-associated urinary tract infections in the intensive care unit. Critical care medicine. 2010 Aug. 38(8 Suppl): S373-9. PMID# 20647795

Smith Jeannina A, Kauffman Carol A. Recognition and prevention of nosocomial invasive fungal infections in the intensive care unit. Critical care medicine. 2010 Aug. 38(8 Suppl): S380-7. PMID# 20647796

Internal Medicine – Metabolism, Endocrinology & Diabetes

Ismail-Beigi Faramarz, Craven Timothy, Banerji Mary Ann, Basile Jan, Calles Jorge, Cohen Robert M, Cuddihy Robert, Cushman William C, Genuth Saul, Grimm Richard H, Hamilton Bruce P, Hoogwerf Byron, Karl Diane, Katz Lois, Krikorian Armand, O'Connor Patrick Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial. Lancet. 2010 Aug 7. 376(9739): 419-30. PMID# 20594588

Heinrich Garrett, Ghosh Sumona, Deangelis Anthony M, Schroeder-Gloeckler Jill M, Patel Payal R, Castaneda Tamara R, Jeffers Shane, Lee Abraham D, Jung Dae Young, Zhang Zhiyou, Opland Darren M, Myers Martin G, Kim Jason K, Najjar Sonia M. Carcinoembryonic antigen-related cell adhesion molecule 2 controls energy balance and peripheral insulin action in mice. Gastroenterology. 2010 Aug. 139(2): 644-52, 652.e1. PMID# 20381490

Perry Maura L, Leinninger Gina M, Chen Rong, Luderman Kathryn D, Yang Hongyan, Gnegy Margaret E, Myers Martin G, Kennedy Robert T. Leptin promotes dopamine transporter and tyrosine hydroxylase activity in the nucleus accumbens of Sprague-Dawley rats. Journal of neurochemistry. 2010 Aug. 114(3): 666-74. PMID# 20412389

Internal Medicine – Molecular Medicine & Genetics

Roberts J S, Karlawish J H, Uhlmann W R, Petersen R C, Green R C. Mild cognitive impairment in clinical care: a survey of American Academy of Neurology members. Neurology. 2010 Aug 3. 75(5): 425-31. PMID# 20679636

Castellsagué Ester, González Sara, Guinó Elisabet, Stevens Kristen N, Borràs Ester, Raymond Victoria M, Lázaro Conxi, Blanco Ignacio, Gruber Stephen B, Capellá Gabriel. Allele-specific expression of APC in adenomatous polyposis families. Gastroenterology. 2010 Aug. 139(2): 439-47, 447.e1. PMID# 20434453

Mallo Moises, Wellik Deneen M, Deschamps Jacqueline. Hox genes and regional patterning of the vertebrate body plan. Developmental biology. 2010 Aug 1. 344(1): 7-15. PMID# 20435029

Zhai Yali, Bommer Guido T, Feng Ying, Wiese Alexandra B, Fearon Eric R, Cho Kathleen R. Loss of estrogen receptor 1 enhances cervical cancer invasion. The American journal of pathology. 2010 Aug. 177(2): 884-95. PMID# 20581058

Internal Medicine – Nephrology

Pennathur Subramaniam, Maitra Dhiman, Byun Jaeman, Sliskovic Inga, Abdulhamid Ibrahim, Saed Ghassan M, Diamond Michael P, Abu-Soud Husam M. Potent antioxidative activity of lycopene: A potential role in scavenging hypochlorous acid. Free radical biology&medicine. 2010 Jul 15. 49(2): 205-13. PMID# 20388538

Gillespie B W, Merion R M, Ortiz-Rios E, Tong L, Shaked A, Brown R S, Ojo A O, Hayashi P H, Berg C L, Abecassis M M, Ashworth A S, Friese C E, Hong J C, Trotter J F, Everhart J E. Database comparison of the adult-to-adult living donor liver transplantation cohort study (A2ALL) and the SRTR U.S. Transplant Registry. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2010 Jul. 10(7): 1621-33. PMID# 20199501

Internal Medicine – Pulmonary and Critical Care

Schneider Dina, Ganesan Shyamala, Comstock Adam T, Meldrum Catherine A, Mahidhara Raja, Goldsmith Adam M, Curtis Jeffrey L, Martinez Fernando J, Hershenson Marc B, Sajjan Umadevi. Increased cytokine response of rhinovirus-infected airway epithelial cells in chronic obstructive pulmonary disease. American journal of respiratory and critical care medicine. 2010 Aug 1. 182(3): 332-40. PMID# 20395558

Zhang Yanmei, Wang Fuyuan, Bhan Urvashi, Huffnagle Gary B, Toews Galen B, Standiford Theodore J, Olszewski Michal A. TLR9 signaling is required for generation of the adaptive immune protection in Cryptococcus neoformans-infected lungs. The American journal of pathology. 2010 Aug. 177(2): 754-65. PMID# 20581055

Internal Medicine – Rheumatology

Patel Dipak R, Richardson Bruce C. Epigenetic mechanisms in lupus. Current opinion in rheumatology. 2010 Sep. 22(5): 478-82. PMID# 20445453

De Almeida Denise E, Ling Song, Pi Xiujun, Hartmann-Scruggs Anne M, Pumpens Paul, Holoshitz Joseph. Immune dysregulation by the rheumatoid arthritis shared epitope. Journal of immunology (Baltimore, Md. : 1950). 2010 Aug 1. 185(3): 1927-34. PMID# 20592276

Rabquer Bradley J, Amin Mohammad A, Teegala Nanditha, Shaheen Matthew K, Tsou Pei-Suen, Ruth Jeffrey H, Lesch Charles A, Imhof Beat A, Koch Alisa E. Junctional adhesion molecule-C is a soluble mediator of angiogenesis. Journal of immunology (Baltimore, Md. : 1950). 2010 Aug 1. 185(3): 1777-85. PMID# 20592283

Ruth Jeffrey H, Arendt Monica D, Amin M Asif, Ahmed Salahuddin, Marotte Hubert, Rabquer Bradley J, Lesch Charles, Lee Solhee, Koch Alisa E. Expression and function of CXCL16 in a novel model of gout. Arthritis and rheumatism. 2010 Aug. 62(8): 2536-44. PMID# 20506383

Medical Education

Andreatta Pamela B, Bullough Alexandra S, Marzano David. Simulation and team training. Clinical obstetrics and gynecology. 2010 Sep. 53(3): 532-44. PMID# 20661038

Andreatta Pamela B, Maslowski Eric, Petty Sean, Shim Woojin, Marsh Michael, Hall Theodore, Stern Susan, Frankel Jen. Virtual reality triage training provides a viable solution for disaster-preparedness. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine. 2010 Aug. 17(8): 870-6. PMID# 20670325

Michigan Nanotechnology Institute for Medicine and Biological Sciences

Ho C-S, Lunney J K, Lee J-H, Franzo-Romain M H, Martens G W, Rowland R R R, Smith D M. Molecular characterization of swine leucocyte antigen class II genes in outbred pig populations. Animal genetics. 2010 Aug. 41(4): 428-32. PMID# 20121817

Microbiology and Immunology

Khare Dheeraj, Wang Bo, Gu Liangcai, Razelun Jamie, Sherman David H, Gerwick William H, Håkansson Kristina, Smith Janet L. Conformational switch triggered by {alpha}-ketoglutarate in a halogenase of curacin A biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 2010 Aug 10. 107(32): 14099-104. PMID# 20660778

Molecular & Behavioral Neuroscience Institute

Wei Qiang, Zhang Li, Liu Xinghui. Clinical diagnosis and treatment of acute fatty liver of pregnancy: a literature review and 11 new cases. The journal of obstetrics and gynaecology research. 2010 Aug. 36(4): 751-6. PMID# 20666940

Schoen Cynthia J, Emery Sarah B, Thorne Marc C, Ammana Hima R, Sliwerska Elzbieta, Arnett Jameson, Hortsch Michael, Hannan Frances, Burmeister Margit, Lesperance Marci M. Increased activity of Diaphanous homolog 3 (DIAPH3)/diaphanous causes hearing defects in humans with auditory neuropathy and in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 2010 Jul 27. 107(30): 13396-401. PMID# 20624953

Molecular & Integrative Physiology

Morris David L, Cho Kae Won, Rui Liangyou. Critical role of the Src homology 2 (SH2) domain of neuronal SH2B1 in the regulation of body weight and glucose homeostasis in mice. Endocrinology. 2010 Aug. 151(8): 3643-51. PMID# 20484460

Neurology

Makhaeva G F, Aksinenko A Y, Sokolov V B, Baskin I I, Palyulin V A, Zefirov N S, Hein N D, Kampf J W, Wijeyesakere S J, Richardson R J. Kinetics and mechanism of inhibition of serine esterases by fluorinated aminophosphonates. Chemico-biological interactions. 2010 Sep 6. 187(1-3): 177-84. PMID# 20035729

Sigolaeva Larisa, Makhaeva Galina, Rudakova Elena, Boltneva Natalia, Porus Marya, Dubacheva Galina, Eremenko Arkadi, Kurochkin Ilya, Richardson Rudy J. Biosensor analysis of blood esterases for organophosphorus compounds exposure assessment: approaches to simultaneous determination of several esterases. Chemico-biological interactions. 2010 Sep 6. 187(1-3): 312-7. PMID# 20097186

Perry Giselle M, Tallaksen-Greene Sara, Kumar Ashish, Heng Mary Y, Kneynsberg Andrew, van Groen Thomas, Detloff Peter J, Albin Roger L, Lesort Mathieu. Mitochondrial calcium uptake capacity as a therapeutic target in the R6/2 mouse model of Huntington's disease. Human molecular genetics. 2010 Sep 1. 19(17): 3354-71. PMID# 20558522

Ramchandren Sindhu, Gruis Kirsten L, Chervin Ronald D, Lisabeth Lynda D, Concannon Maryann, Wolfe James, Albers James W, Brown Devin L. Hypoglossal nerve conduction findings in obstructive sleep apnea. Muscle&nerve. 2010 Aug. 42(2): 257-61. PMID# 20544939

Lalor Stephen J, Segal Benjamin M. Lymphoid chemokines in the CNS. Journal of neuroimmunology. 2010 Jul 27. 224(1-2): 56-61. PMID# 20605642

Vilensky Joel A, Gilman Sid, McCall Sherman. A historical analysis of the relationship between encephalitis lethargica and postencephalitic parkinsonism: a complex rather than a direct relationship. Movement disorders : official journal of the Movement Disorder Society. 2010 Jul 15. 25(9): 1116-23. PMID# 20629120

Vilensky Joel A, Gilman Sid, McCall Sherman. Does the historical literature on encephalitis lethargica support a simple (direct) relationship with postencephalitic Parkinsonism? Movement disorders : official journal of the Movement Disorder Society. 2010 Jul 15. 25(9): 1124-30. PMID# 20629127

Neurosurgery

Xiang Jianming, Jiang Huidi, Hu Yongjun, Smith David E, Keep Richard F. Kyotorphin transport and metabolism in rat and mouse neonatal astrocytes. Brain research. 2010 Aug 6. 1347: 11-8. PMID# 20537989

Obstetrics & Gynecology

Dalton Vanessa. Perioperative venous thromboembolism and antibiotic prophylaxis in obstetrics and gynecology. Clinical obstetrics and gynecology. 2010 Sep. 53(3): 521-31. PMID# 20661037

Hsu Yvonne, Chen Luyun, Tumbarello Julie, Ashton-Miller James A, DeLancey John O L. In vivo assessment of anterior compartment compliance and its relation to prolapse. International urogynecology journal and pelvic floor dysfunction. 2010 Sep. 21(9): 1111-5. PMID# 20440477

Larson Kindra A, Hsu Yvonne, Chen Luyun, Ashton-Miller James A, DeLancey John O L. Magnetic resonance imaging-based three-dimensional model of anterior vaginal wall position at rest and maximal strain in women with and without prolapse. International urogynecology journal and pelvic floor dysfunction. 2010 Sep. 21(9): 1103-9. PMID# 20449568

Sowers MaryFran R, Karvonen-Gutierrez Carrie A. The evolving role of obesity in knee osteoarthritis. Current opinion in rheumatology. 2010 Sep. 22(5): 533-7. PMID# 20485173

Hamama Lydia, Rauch Sheila A M, Sperlich Mickey, Defever Erin, Seng Julia S. Previous experience of spontaneous or elective abortion and risk for posttraumatic stress and depression during subsequent pregnancy. Depression and anxiety. 2010 Aug. 27(8): 699-707. PMID# 20577979

Napadow Vitaly, Lacount Lauren, Park Kyungmo, As-Sanie Sawsan, Clauw Daniel J, Harris Richard E. Intrinsic brain connectivity in fibromyalgia is associated with chronic pain intensity. Arthritis and rheumatism. 2010 Aug. 62(8): 2545-55. PMID# 20506181

Ophthalmology & Visual Sciences

Roger Jerome E, Nellissery Jacob, Kim Douglas S, Swaroop Anand. Sumoylation of bZIP transcription factor NRL modulates target gene expression during photoreceptor differentiation. The Journal of biological chemistry. 2010 Aug 13. 285(33): 25637-44. PMID# 20551322

Manookin Michael B, Weick Michael, Stafford Benjamin K, Demb Jonathan B. NMDA receptor contributions to visual contrast coding. Neuron. 2010 Jul 29. 67(2): 280-93. PMID# 20670835

Moroi Sayoko E. Eyelash preservation during chemotherapy and topical prostaglandin therapy. Archives of internal medicine. 2010 Jul 26. 170(14): 1269-70. PMID# 20660849

Orthopaedic Surgery

Bedi Asheesh, Dines Joshua, Warren Russell F, Dines David M. Massive tears of the rotator cuff. The Journal of bone and joint surgery. American volume. 2010 Aug 4. 92(9): 1894-908. PMID# 20686065

Schilling Peter L, Hallstrom Brian R, Birkmeyer John D, Carpenter James E. Prioritizing perioperative quality improvement in orthopaedic surgery. The Journal of bone and joint surgery. American volume. 2010 Aug 4. 92(9): 1884-9. PMID# 20686063

Bowman Karl F, Fox Jeremy, Sekiya Jon K. A clinically relevant review of hip biomechanics. Arthroscopy : the journal of arthroscopic&related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association. 2010 Aug. 26(8): 1118-29. PMID# 20678712

Kozloff Kenneth M, Volakis Leo I, Marini Joan C, Caird Michelle S. Near-infrared fluorescent probe traces bisphosphonate delivery and retention in vivo. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2010 Aug. 25(8): 1748-58. PMID# 20200982

Musahl Volker, Citak Musa, O'Loughlin Padhraig F, Choi Daniel, Bedi Asheesh, Pearle Andrew D. The effect of medial versus lateral meniscectomy on the stability of the anterior cruciate ligament-deficient knee. The American journal of sports medicine. 2010 Aug. 38(8): 1591-7. PMID# 20530720

Srinivasan Ramesh C, Shah Apurva S, Jebson Peter J L. New treatment options for Dupuytren's surgery: collagenase and percutaneous aponeurotomy. The Journal of hand surgery. 2010 Aug. 35(8): 1362-4. PMID# 20434276

Otolaryngology

Attar Esra, Dey Subhojit, Hablas Ahmad, Seifeldin Ibrahim A, Ramadan Mohamed, Rozek Laura S, Soliman Amr S. Head and neck cancer in a developing country: a population-based perspective across 8 years. Oral oncology. 2010 Aug. 46(8): 591-6. PMID# 20619719

Moyer Jeffrey S. Reconstruction of extensive nasal defects with staged bilateral paramedian forehead flaps. Annals of plastic surgery. 2010 Aug. 65(2): 188-92. PMID# 20606589

Sakai V T, Zhang Z, Dong Z, Neiva K G, Machado M A A M, Shi S, Santos C F, Nör J E. SHED differentiate into functional odontoblasts and endothelium. Journal of dental research. 2010 Aug. 89(8): 791-6. PMID# 20395410

Schoen Cynthia J, Emery Sarah B, Thorne Marc C, Ammana Hima R, Sliwerska Elzbieta, Arnett Jameson, Hortsch Michael, Hannan Frances, Burmeister Margit, Lesperance Marci M. Increased activity of Diaphanous homolog 3 (DIAPH3)/diaphanous causes hearing defects in humans with auditory neuropathy and in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 2010 Jul 27. 107(30): 13396-401. PMID# 20624953

Pathology

Fortna Ryan R, Gudjonsson Johann E, Seidel Gregory, Dicostanzo Damian, Jacobson Mark, Kopelman Margaret, Patel Rajiv M. Persistent pruritic papules and plaques: a characteristic histopathologic presentation seen in a subset of patients with adult-onset and juvenile Still's disease. Journal of cutaneous pathology. 2010 Sep. 37(9): 932-7. PMID# 20546088

Harms Paul W, Bandarchi Bizhan, Ma Linglei. CD163 expression in leukemia cutis. Journal of cutaneous pathology. 2010 Sep. 37(9): 953-7. PMID# 20175823

Patel Risha M, VAN Kan Jan A L, Bailey Andy M, Foster Gary D. Inadvertent gene silencing of argininosuccinate synthase (bcass1) in Botrytis cinerea by the pLOB1 vector system. Molecular plant pathology. 2010 Sep 1. 11(5): 613-24. PMID# 20696000

Yamashita Junro, McCauley Laurie K, Van Poznak Catherine. Updates on osteonecrosis of the jaw. Current opinion in supportive and palliative care. 2010 Sep. 4(3): 200-6. PMID# 20657284

Lukacs Nicholas W, Smit Joost J, Mukherjee Sumanta, Morris Susan B, Nunez Gabriel, Lindell Dennis M. Respiratory virus-induced TLR7 activation controls IL-17-associated increased mucus via IL-23 regulation. Journal of immunology (Baltimore, Md. : 1950). 2010 Aug 15. 185(4): 2231-9. PMID# 20624950

Nagarkar Deepti R, Bowman Emily R, Schneider Dina, Wang Qiong, Shim Jee, Zhao Ying, Linn Marisa J, McHenry Christina L, Gosangi Babina, Bentley J Kelley, Tsai Wan C, Sajjan Umadevi S, Lukacs Nicholas W, Hershenson Marc B. Rhinovirus infection of allergen-sensitized and -challenged mice induces eotaxin release from functionally polarized macrophages. Journal of immunology (Baltimore, Md. : 1950). 2010 Aug 15. 185(4): 2525-35. PMID# 20644177

Lieber Michael R, Wilson Thomas E. SnapShot: Nonhomologous DNA end joining (NHEJ). Cell. 2010 Aug 6. 142(3): 496-496.e1. PMID# 20691907

Annesley Thomas M. Put your best figure forward: line graphs and scattergrams. Clinical chemistry. 2010 Aug. 56(8): 1229-33. PMID# 20551381

Hashimoto Naozumi, Phan Sem H, Imaizumi Kazuyoshi, Matsuo Masaki, Nakashima Harunori, Kawabe Tsutomu, Shimokata Kaoru, Hasegawa Yoshinori. Endothelial-mesenchymal transition in bleomycin-induced pulmonary fibrosis. American journal of respiratory cell and molecular biology. 2010 Aug. 43(2): 161-72. PMID# 19767450

Maine Gabriel N, Li Haiying, Zaidi Iram W, Basrur Venkatesha, Elenitoba-Johnson Kojo S J, Burstein Ezra. A bimolecular affinity purification method under denaturing conditions for rapid isolation of a ubiquitinated protein for mass spectrometry analysis. Nature protocols. 2010 Aug. 5(8): 1447-59. PMID# 20671728

Monte Nicolas M, Webster Kaitlyn A, Neuberg Donna, Dressler Gregory R, Mutter George L. Joint loss of PAX2 and PTEN expression in endometrial precancers and cancer. Cancer research. 2010 Aug 1. 70(15): 6225-32. PMID# 20631067

Schmidt Lindsay A, Olsen Stephen H, McHugh Jonathan B. Cutaneous adnexal differentiation and stromal metaplasia in palate pleomorphic adenomas: a potential diagnostic pitfall that may be mistaken for malignancy. The American journal of surgical pathology. 2010 Aug. 34(8): 1205-10. PMID# 20661019

Zhai Yali, Bommer Guido T, Feng Ying, Wiese Alexandra B, Fearon Eric R, Cho Kathleen R. Loss of estrogen receptor 1 enhances cervical cancer invasion. The American journal of pathology. 2010 Aug. 177(2): 884-95. PMID# 20581058

Pradipta Ambara R, Fujimoto Yukari, Hasegawa Mizuho, Inohara Naohiro, Fukase Koichi. Characterization of natural human nucleotide-binding oligomerization domain protein 1 (Nod1) ligands from bacterial culture supernatant for elucidation of immune modulators in the environment. The Journal of biological chemistry. 2010 Jul 30. 285(31): 23607-13. PMID# 20519512

Park Kyung, Tomlins Scott A, Mudaliar Kumaran M, Chiu Ya-Lin, Esgueva Raquel, Mehra Rohit, Suleman Khalid, Varambally Sooryanarayana, Brenner John C, MacDonald Theresa, Srivastava Abhishek, Tewari Ashutosh K, Sathyanarayana Ubaradka, Nagy Dea, Pestano Gar Antibody-based detection of ERG rearrangement-positive prostate cancer. Neoplasia (New York, N.Y.). 2010 Jul. 12(7): 590-8. PMID# 20651988

Pediatrics & Communicable Diseases

Houle Christy R, Leo Harvey L, Clark Noreen M. A developmental, community, and psychosocial approach to food allergies in children. Current allergy and asthma reports. 2010 Sep. 10(5): 381-6. PMID# 20464533

Woolford Susan J, Clark Sarah J, Gebremariam Achamyeleh, Davis Matthew M, Freed Gary L. Physicians' perspectives on referring obese adolescents to pediatric multidisciplinary weight management programs. Clinical pediatrics. 2010 Sep. 49(9): 871-5. PMID# 20522620

Nagarkar Deepti R, Bowman Emily R, Schneider Dina, Wang Qiong, Shim Jee, Zhao Ying, Linn Marisa J, McHenry Christina L, Gosangi Babina, Bentley J Kelley, Tsai Wan C, Sajjan Umadevi S, Lukacs Nicholas W, Hershenson Marc B. Rhinovirus infection of allergen-sensitized and -challenged mice induces eotaxin release from functionally polarized macrophages. Journal of immunology (Baltimore, Md. : 1950). 2010 Aug 15. 185(4): 2525-35. PMID# 20644177

Yoon Esther Y, Clark Sarah J, Gorman Richard, Nelson Sheryl, O'Connor Karen G, Freed Gary L. Differences in pediatric drug information sources used by general versus subspecialist pediatricians. Clinical pediatrics. 2010 Aug. 49(8): 743-9. PMID# 20522611

Shih Terry, Gurney James G, Bove Edward L, Devaney Eric J, Hirsch Jennifer C, Ohye Richard G. Performance of bicuspidized pulmonary allografts compared with standard trileaflet allografts. The Annals of thoracic surgery. 2010 Aug. 90(2): 610-3. PMID# 20667359

Veiga-Lopez Almudena, Lee James S, Padmanabhan Vasantha. Developmental programming: insulin sensitizer treatment improves reproductive function in prenatal testosterone-treated female sheep. Endocrinology. 2010 Aug. 151(8): 4007-17. PMID# 20555028

Raghavan Shreya, Miyasaka Eiichi A, Hashish Mohamed, Somara Sita, Gilmont Robert R, Teitelbaum Daniel H, Bitar Khalil N. Successful implantation of physiologically functional bioengineered mouse internal anal sphincter. American journal of physiology. Gastrointestinal and liver physiology. 2010 Aug. 299(2): G430-9. PMID# 20558766

Schneider Dina, Ganesan Shyamala, Comstock Adam T, Meldrum Catherine A, Mahidhara Raja, Goldsmith Adam M, Curtis Jeffrey L, Martinez Fernando J, Hershenson Marc B, Sajjan Umadevi. Increased cytokine response of rhinovirus-infected airway epithelial cells in chronic obstructive pulmonary disease. American journal of respiratory and critical care medicine. 2010 Aug 1. 182(3): 332-40. PMID# 20395558

Carter R Colin, Jacobson Joseph L, Burden Matthew J, Armony-Sivan Rinat, Dodge Neil C, Angelilli Mary Lu, Lozoff Betsy, Jacobson Sandra W. Iron deficiency anemia and cognitive function in infancy. Pediatrics. 2010 Aug. 126(2): e427-34. PMID# 20660551

Peirano Patricio D, Algarín Cecilia R, Chamorro Rodrigo A, Reyes Sussanne C, Durán Samuel A, Garrido Marcelo I, Lozoff Betsy. Sleep alterations and iron deficiency anemia in infancy. Sleep medicine. 2010 Aug. 11(7): 637-42. PMID# 20620103

Magenau John M, Qin Xuemei, Tawara Isao, Rogers Clare E, Kitko Carrie, Schlough Matthew, Bickley Daniel, Braun Thomas M, Jang Pil-Sang, Lowler Kathleen P, Jones Dawn M, Choi Sung W, Reddy Pavan, Mineishi Shin, Levine John E, Ferrara James L M, Paczesny So Frequency of CD4(+)CD25(hi)FOXP3(+) regulatory T cells has diagnostic and prognostic value as a biomarker for acute graft-versus-host-disease. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 2010 Jul. 16(7): 907-14. PMID# 20302964

Davis Matthew M, Wortley Pascale M, Ndiaye Serigne M, Cowan Anne E, Osta Amanda D, Clark Sarah J. Influenza vaccine for high-risk non-elderly adults: A national survey of subspecialists. Human vaccines. 2010 May. 4(3): 229-33. PMID# 18414061

Pharmacology

Diaz José A, Hawley Angela E, Alvarado Christine M, Berguer Alexandra M, Baker Nichole K, Wrobleski Shirley K, Wakefield Thomas W, Lucchesi Benedict R, Myers Daniel D. Thrombogenesis with continuous blood flow in the inferior vena cava. A novel mouse model. Thrombosis and haemostasis. 2010 Aug 2. 104(2): 366-75. PMID# 20589322

Perry Maura L, Leinninger Gina M, Chen Rong, Luderman Kathryn D, Yang Hongyan, Gnegy Margaret E, Myers Martin G, Kennedy Robert T. Leptin promotes dopamine transporter and tyrosine hydroxylase activity in the nucleus accumbens of Sprague-Dawley rats. Journal of neurochemistry. 2010 Aug. 114(3): 666-74. PMID# 20412389

Merrins Matthew J, Fendler Bernard, Zhang Min, Sherman Arthur, Bertram Richard, Satin Leslie S. Metabolic oscillations in pancreatic islets depend on the intracellular Ca2+ level but not Ca2+ oscillations. Biophysical journal. 2010 Jul 7. 99(1): 76-84. PMID# 20655835

Narasimhan Diwahar, Nance Mark R, Gao Daquan, Ko Mei-Chuan, Macdonald Joanne, Tamburi Patricia, Yoon Dan, Landry Donald M, Woods James H, Zhan Chang-Guo, Tesmer John J G, Sunahara Roger K. Structural analysis of thermostabilizing mutations of cocaine esterase. Protein engineering, design&selection : PEDS. 2010 Jul. 23(7): 537-47. PMID# 20436035

Psychiatry

Walton Maureen A, Chermack Stephen T, Shope Jean T, Bingham C Raymond, Zimmerman Marc A, Blow Frederic C, Cunningham Rebecca M. Effects of a brief intervention for reducing violence and alcohol misuse among adolescents: a randomized controlled trial. JAMA : the journal of the American Medical Association. 2010 Aug 4. 304(5): 527-35. PMID# 20682932

Hamama Lydia, Rauch Sheila A M, Sperlich Mickey, Defever Erin, Seng Julia S. Previous experience of spontaneous or elective abortion and risk for posttraumatic stress and depression during subsequent pregnancy. Depression and anxiety. 2010 Aug. 27(8): 699-707. PMID# 20577979

Heitzeg Mary M, Nigg Joel T, Yau Wai-Ying Wendy, Zucker Robert A, Zubieta Jon-Kar. Striatal dysfunction marks preexisting risk and medial prefrontal dysfunction is related to problem drinking in children of alcoholics. Biological psychiatry. 2010 Aug 1. 68(3): 287-95. PMID# 20416863

Labuschagne I, Croft R J, Phan K L, Nathan P J. Augmenting serotonin neurotransmission with citalopram modulates emotional expression decoding but not structural encoding of moderate intensity sad facial emotional stimuli: an event-related potential (ERP) investigation. Journal of psychopharmacology (Oxford, England). 2010 Aug. 24(8): 1153-64. PMID# 18832432

Zivin Kara, Ratliff Scott, Heisler Michele M, Langa Kenneth M, Piette John D. Factors influencing cost-related nonadherence to medication in older adults: a conceptually based approach. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research. 2010 Jun-Jul. 13(4): 338-45. PMID# 20070641

Zucker Robert A. Addiction research centres and the nurturing of creativity. University of Michigan Addiction Research Center (UMARC): development, evolution, and direction. Addiction (Abingdon, England). 2010 Jun. 105(6): 966-73. PMID# 20331547

Radiation Oncology

Galbán Stefanie, Brisset Jean-Christophe, Rehemtulla Alnawaz, Chenevert Thomas L, Ross Brian D, Galbán Craig J. Diffusion-weighted MRI for assessment of early cancer treatment response. Current pharmaceutical biotechnology. 2010 Sep 1. 11(6): 701-8. PMID# 20504274

Zhang L, Zhang M, Yang S, Cao Y, Bingrong Zhang S, Yin L, Tian Y, Ma Y, Zhang A, Okunieff P, Zhang L. A new biodosimetric method: branched DNA-based quantitative detection of B1 DNA in mouse plasma. The British journal of radiology. 2010 Aug. 83(992): 694-701. PMID# 20675464

Radiology

Harvey John A, Haverland Nathan P, Kearfott Kimberlee J. Characterization of the glow-peak fading properties of six common thermoluminescent materials. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 2010 Oct. 68(10): 1988-2000. PMID# 20554212

Carlos Ruth C. Comparative effectiveness research: what does it mean for imaging? Academic radiology. 2010 Sep. 17(9): 1071-2. PMID# 20692618

Galbán Stefanie, Brisset Jean-Christophe, Rehemtulla Alnawaz, Chenevert Thomas L, Ross Brian D, Galbán Craig J. Diffusion-weighted MRI for assessment of early cancer treatment response. Current pharmaceutical biotechnology. 2010 Sep 1. 11(6): 701-8. PMID# 20504274

Borden Bradley A, Yockman James, Kim Sung Wan. Thermoresponsive hydrogel as a delivery scaffold for transfected rat mesenchymal stem cells. Molecular pharmaceutics. 2010 Aug 2. 7(4): 963-8. PMID# 20583814

Dave Maneesh, Elmunzer B Joseph, Dwamena Ben A, Higgins Peter D R. Primary sclerosing cholangitis: meta-analysis of diagnostic performance of MR cholangiopancreatography. Radiology. 2010 Aug. 256(2): 387-96. PMID# 20656832

Hiratzka Loren F, Bakris George L, Beckman Joshua A, Bersin Robert M, Carr Vincent F, Casey Donald E, Eagle Kim A, Hermann Luke K, Isselbacher Eric M, Kazerooni Ella A, Kouchoukos Nicholas T, Lytle Bruce W, Milewicz Dianna M, Reich David L, Sen Souvik, Sh Special Article: 2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM Guidelines for the diagnosis and management of patients with thoracic aortic disease: Executive summary: A report of the American College of Cardiology Foundation/American Heart Association Anesthesia and analgesia. 2010 Aug. 111(2): 279-315. PMID# 20664093

Hiratzka Loren F, Bakris George L, Beckman Joshua A, Bersin Robert M, Carr Vincent F, Casey Donald E, Eagle Kim A, Hermann Luke K, Isselbacher Eric M, Kazerooni Ella A, Kouchoukos Nicholas T, Lytle Bruce W, Milewicz Dianna M, Reich David L, Sen Souvik, Sh 2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM guidelines for the diagnosis and management of patients with thoracic aortic disease: executive summary. A report of the American College of Cardiology Foundation/American Heart Association Task Force on Pra Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography&Interventions. 2010 Aug 1. 76(2): E43-86. PMID# 20687249

Khan Asra S, Hussain Hero K, Johnson Timothy D, Weadock William J, Pelletier Shawn J, Marrero Jorge A. Value of delayed hypointensity and delayed enhancing rim in magnetic resonance imaging diagnosis of small hepatocellular carcinoma in the cirrhotic liver. Journal of magnetic resonance imaging : JMRI. 2010 Aug. 32(2): 360-6. PMID# 20677263

Lehnert A L, Kearfott K J. An equilibrium-based model for measuring environmental radon using charcoal canisters. Health physics. 2010 Aug. 99 Suppl 2: S154-63. PMID# 20622564

Sundaram B, Robbins J B, Zeglis M D, Scheiman J M, Simeone D M, Francis I R. Mesenteric venous collateral vessels mimicking cystic pancreatic neoplasm. The British journal of radiology. 2010 Aug. 83(992): e175-8. PMID# 20675462

Davenport Matthew S, Caoili Elaine M, Cohan Richard H, Hoff Carrie N, Ellis James H. Pancreatic manifestations of von Hippel-Lindau disease-effect of imaging on clinical management. Journal of computer assisted tomography. 2010 Jul. 34(4): 517-22. PMID# 20657218

Elsayes Khaled M, Menias Christine O, Siegel Cary L, Narra Vamsidhar R, Kanaan Yassine, Hussain Hero K. Magnetic resonance characterization of pheochromocytomas in the abdomen and pelvis: imaging findings in 18 surgically proven cases. Journal of computer assisted tomography. 2010 Jul. 34(4): 548-53. PMID# 20657223

Trout Andrew T, Elsayes Khaled M, Ellis James H, Francis Isaac R. Imaging of acute pancreatitis: prognostic value of computed tomographic findings. Journal of computer assisted tomography. 2010 Jul. 34(4): 485-95. PMID# 20657214

Surgery

Birkmeyer Nancy J O, Share David, Baser Onur, Carlin Arthur M, Finks Jonathan F, Pesta Carl M, Genaw Jeffrey A, Birkmeyer John D. Preoperative placement of inferior vena cava filters and outcomes after gastric bypass surgery. Annals of surgery. 2010 Aug. 252(2): 313-8. PMID# 20622663

Birkmeyer Nancy J O, Dimick Justin B, Share David, Hawasli Abdelkader, English Wayne J, Genaw Jeffrey, Finks Jonathan F, Carlin Arthur M, Birkmeyer John D. Hospital complication rates with bariatric surgery in Michigan. JAMA : the journal of the American Medical Association. 2010 Jul 28. 304(4): 435-42. PMID# 20664044

Surgery – Cardiac Surgery

Shih Terry, Gurney James G, Bove Edward L, Devaney Eric J, Hirsch Jennifer C, Ohye Richard G. Performance of bicuspidized pulmonary allografts compared with standard trileaflet allografts. The Annals of thoracic surgery. 2010 Aug. 90(2): 610-3. PMID# 20667359

Surgery – General Surgery

Liu Yang, Wu Xiao, He Cheng, Li Zhongyi, Duan Chunying. Metal-organic polyhedra for selective sensing of ribonucleosides through the cooperation of hydrogen-bonding interactions. Dalton transactions (Cambridge, England : 2003). 2010 Sep 7. 39(33): 7727-32. PMID# 20652198

Schilling Peter L, Hallstrom Brian R, Birkmeyer John D, Carpenter James E. Prioritizing perioperative quality improvement in orthopaedic surgery. The Journal of bone and joint surgery. American volume. 2010 Aug 4. 92(9): 1884-9. PMID# 20686063

Birkmeyer Nancy J O, Share David, Baser Onur, Carlin Arthur M, Finks Jonathan F, Pesta Carl M, Genaw Jeffrey A, Birkmeyer John D. Preoperative placement of inferior vena cava filters and outcomes after gastric bypass surgery. Annals of surgery. 2010 Aug. 252(2): 313-8. PMID# 20622663

Englesbe Michael J, Patel Shaun P, He Kevin, Lynch Raymond J, Schaubel Douglas E, Harbaugh Calista, Holcombe Sven A, Wang Stewart C, Segev Dorry L, Sonnenday Christopher J. Sarcopenia and mortality after liver transplantation. Journal of the American College of Surgeons. 2010 Aug. 211(2): 271-8. PMID# 20670867

Englesbe Michael J, Schaubel Douglas E, Cai Shijie, Guidinger Mary K, Merion Robert M. Portal vein thrombosis and liver transplant survival benefit. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2010 Aug. 16(8): 999-1005. PMID# 20677291

Ghaferi Amir A, Mathur Amit K, Sonnenday Christopher J, Dimick Justin B. Adverse outcomes in patients with chronic liver disease undergoing colorectal surgery. Annals of surgery. 2010 Aug. 252(2): 345-50. PMID# 20622652

Hu Bin, Colletti Lisa M. CXC receptor-2 knockout genotype increases X-linked inhibitor of apoptosis protein and protects mice from acetaminophen hepatotoxicity. Hepatology (Baltimore, Md.). 2010 Aug. 52(2): 691-702. PMID# 20683965

Ingraham Angela M, Xiong Wei, Hemmila Mark R, Shafi Shahid, Goble Sandra, Neal Melanie L, Nathens Avery B. The attributable mortality and length of stay of trauma-related complications: a matched cohort study. Annals of surgery. 2010 Aug. 252(2): 358-62. PMID# 20622658

Khan Asra S, Hussain Hero K, Johnson Timothy D, Weadock William J, Pelletier Shawn J, Marrero Jorge A. Value of delayed hypointensity and delayed enhancing rim in magnetic resonance imaging diagnosis of small hepatocellular carcinoma in the cirrhotic liver. Journal of magnetic resonance imaging : JMRI. 2010 Aug. 32(2): 360-6. PMID# 20677263

Mathur Amit K, Ghaferi Amir A, Osborne Nicholas H, Pawlik Timothy M, Campbell Darrell A, Englesbe Michael J, Welling Theodore H. Body mass index and adverse perioperative outcomes following hepatic resection. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 2010 Aug. 14(8): 1285-91. PMID# 20532666

Miller Barbra S. Fine needle aspiration--is there a difference in indication for use based on gender? The Journal of surgical research. 2010 Aug. 162(2): 165-7. PMID# 20189587

Napolitano Lena M. Use of severity scoring and stratification factors in clinical trials of hospital-acquired and ventilator-associated pneumonia. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2010 Aug 1. 51 Suppl 1: S67-80. PMID# 20597675

Osborne Nicholas H, Ko Clifford Y, Upchurch Gilbert R, Dimick Justin B. Evaluating parsimonious risk-adjustment models for comparing hospital outcomes with vascular surgery. Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter. 2010 Aug. 52(2): 400-5. PMID# 20670776

Birkmeyer Nancy J O, Dimick Justin B, Share David, Hawasli Abdelkader, English Wayne J, Genaw Jeffrey, Finks Jonathan F, Carlin Arthur M, Birkmeyer John D. Hospital complication rates with bariatric surgery in Michigan. JAMA : the journal of the American Medical Association. 2010 Jul 28. 304(4): 435-42. PMID# 20664044

Gillespie B W, Merion R M, Ortiz-Rios E, Tong L, Shaked A, Brown R S, Ojo A O, Hayashi P H, Berg C L, Abecassis M M, Ashworth A S, Friese C E, Hong J C, Trotter J F, Everhart J E. Database comparison of the adult-to-adult living donor liver transplantation cohort study (A2ALL) and the SRTR U.S. Transplant Registry. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2010 Jul. 10(7): 1621-33. PMID# 20199501

Moote Marc, Englesbe Michael, Bahl Vinita, Hu Hsou Mei, Thompson Maureen, Kubus James, Campbell Darrell. PA-driven VTE risk assessment improves compliance with recommended prophylaxis. JAAPA : official journal of the American Academy of Physician Assistants. 2010 Jun. 23(6): 27-30, 32-5. PMID# 20653258

Sarkar B, Napolitano L M. Necrotizing soft tissue infections. Minerva chirurgica. 2010 Jun. 65(3): 347-62. PMID# 20668422

Surgery – Oral & Maxillofacial Surgery

Saito Eiji, Kang Heesuk, Taboas Juan M, Diggs Alisha, Flanagan Colleen L, Hollister Scott J. Experimental and computational characterization of designed and fabricated 50:50 PLGA porous scaffolds for human trabecular bone applications. Journal of materials science. Materials in medicine. 2010 Aug. 21(8): 2371-83. PMID# 20524047

Surgery – Pediatric Surgery

Raghavan Shreya, Miyasaka Eiichi A, Hashish Mohamed, Somara Sita, Gilmont Robert R, Teitelbaum Daniel H, Bitar Khalil N. Successful implantation of physiologically functional bioengineered mouse internal anal sphincter. American journal of physiology. Gastrointestinal and liver physiology. 2010 Aug. 299(2): G430-9. PMID# 20558766

Surgery – Plastic Surgery

Burns Patricia B, Chung Kevin C. Developing good clinical questions and finding the best evidence to answer those questions. Plastic and reconstructive surgery. 2010 Aug. 126(2): 613-8. PMID# 20679843

Pannucci Christopher J, Wilkins Edwin G. Identifying and avoiding bias in research. Plastic and reconstructive surgery. 2010 Aug. 126(2): 619-25. PMID# 20679844

Schwarz Daniel A, Arman Krikor G, Kakwan Mehreen S, Jamali Ameen M, Buchman Steven R. Analysis of the biomechanical properties of the mandible after unilateral distraction osteogenesis. Plastic and reconstructive surgery. 2010 Aug. 126(2): 533-42. PMID# 20375764

Streu Rachel, Hawley Sarah, Gay Ashley, Salem Barbara, Abrahamse Paul, Alderman Amy K. Satisfaction with career choice among U.S. plastic surgeons: results from a national survey. Plastic and reconstructive surgery. 2010 Aug. 126(2): 636-42. PMID# 20375767

Surgery – Thoracic Surgery

Schneider Dina, Ganesan Shyamala, Comstock Adam T, Meldrum Catherine A, Mahidhara Raja, Goldsmith Adam M, Curtis Jeffrey L, Martinez Fernando J, Hershenson Marc B, Sajjan Umadevi. Increased cytokine response of rhinovirus-infected airway epithelial cells in chronic obstructive pulmonary disease. American journal of respiratory and critical care medicine. 2010 Aug 1. 182(3): 332-40. PMID# 20395558

Surgery – Vascular Surgery

Diaz José A, Hawley Angela E, Alvarado Christine M, Berguer Alexandra M, Baker Nichole K, Wrobleski Shirley K, Wakefield Thomas W, Lucchesi Benedict R, Myers Daniel D. Thrombogenesis with continuous blood flow in the inferior vena cava. A novel mouse model. Thrombosis and haemostasis. 2010 Aug 2. 104(2): 366-75. PMID# 20589322

Criado Enrique, Berguer Ramon, Greenfield Lazar. The spectrum of arterial compression at the thoracic outlet. Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter. 2010 Aug. 52(2): 406-11. PMID# 20541346

Osborne Nicholas H, Ko Clifford Y, Upchurch Gilbert R, Dimick Justin B. Evaluating parsimonious risk-adjustment models for comparing hospital outcomes with vascular surgery. Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter. 2010 Aug. 52(2): 400-5. PMID# 20670776

Trimarchi Santi, Jonker Frederik H W, Muhs Bart E, Grassi Viviana, Righini Paolo, Upchurch Gilbert R, Rampoldi Vincenzo. Long-term outcomes of surgical aortic fenestration for complicated acute type B aortic dissections. Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter. 2010 Aug. 52(2): 261-6. PMID# 20573474

Unit for Laboratory Animal Medicine

Harper James M, Wilkinson J Erby, Miller Richard A. Macrophage migration inhibitory factor-knockout mice are long lived and respond to caloric restriction. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2010 Jul. 24(7): 2436-42. PMID# 20219983

Urology

Evans Blake, Montie James E, Gilbert Scott M. Incontinent or continent urinary diversion: how to make the right choice. Current opinion in urology. 2010 Sep. 20(5): 421-5. PMID# 20616739

Clemens J Quentin. Afferent neurourology: an epidemiological perspective. The Journal of urology. 2010 Aug. 184(2): 432-9. PMID# 20620394

Hollingsworth John M, Zhang Yun, Krein Sarah L, Ye Zaojun, Hollenbeck Brent K. Understanding the variation in treatment intensity among patients with early stage bladder cancer. Cancer. 2010 Aug 1. 116(15): 3587-94. PMID# 20564128

Weizer Alon Z, Montgomery Jeffrey S. The role of lymphadenectomy in minimally invasive urologic oncology. Journal of endourology / Endourological Society. 2010 Aug. 24(8): 1229-40. PMID# 20629570

Berry Sandra H, Bogart Laura M, Pham Chau, Liu Karin, Nyberg Leroy, Stoto Michael, Suttorp Marika, Clemens J Quentin. Development, validation and testing of an epidemiological case definition of interstitial cystitis/painful bladder syndrome. The Journal of urology. 2010 May. 183(5): 1848-52. PMID# 20303099